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4-diphenylacetoxy-1,1-dimethylpiperidinium and Psychotic Disorders

4-diphenylacetoxy-1,1-dimethylpiperidinium has been researched along with Psychotic Disorders in 1 studies

4-diphenylacetoxy-1,1-dimethylpiperidinium: muscarinic receptor antagonist; RN given refers to parent cpd; do not confuse abbreviation 4-DAMP with a similar cpd which does not contain dimethyl groups
4-DAMP(1+) : A quaternary ammonium salt obtained by formal methylation of the tertiary amino function of 4-diphenylacetoxy-N-methylpiperidine.

Psychotic Disorders: Disorders in which there is a loss of ego boundaries or a gross impairment in reality testing with delusions or prominent hallucinations. (From DSM-IV, 1994)

Research Excerpts

ExcerptRelevanceReference
"Neuropsychiatric behaviours in Alzheimer's disease (AD) patients have been associated with neocortical alterations of presynaptic cholinergic and muscarinic M2 receptor markers."1.35Loss of [3H]4-DAMP binding to muscarinic receptors in the orbitofrontal cortex of Alzheimer's disease patients with psychosis. ( Chen, CP; Esiri, MM; Francis, PT; Lai, MK; Tsang, SW; Wong, PT, 2008)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Tsang, SW1
Francis, PT1
Esiri, MM1
Wong, PT1
Chen, CP1
Lai, MK1

Other Studies

1 other study available for 4-diphenylacetoxy-1,1-dimethylpiperidinium and Psychotic Disorders

ArticleYear
Loss of [3H]4-DAMP binding to muscarinic receptors in the orbitofrontal cortex of Alzheimer's disease patients with psychosis.
    Psychopharmacology, 2008, Volume: 198, Issue:2

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Animals; CHO Cells; Cohort Studies; Cricetinae; Cricetul

2008