4-diphenylacetoxy-1,1-dimethylpiperidinium has been researched along with Pneumonia in 1 studies
4-diphenylacetoxy-1,1-dimethylpiperidinium: muscarinic receptor antagonist; RN given refers to parent cpd; do not confuse abbreviation 4-DAMP with a similar cpd which does not contain dimethyl groups
4-DAMP(1+) : A quaternary ammonium salt obtained by formal methylation of the tertiary amino function of 4-diphenylacetoxy-N-methylpiperidine.
Pneumonia: Infection of the lung often accompanied by inflammation.
| Excerpt | Relevance | Reference |
|---|---|---|
| "LPS-induced acute lung injury (ALI) was significantly improved by atropine (a non-selective mAChR antagonist) and 4-DAMP (a M3 mAChR antagonist), as indicated by the diminution of neutrophil infiltration, pulmonary vascular permeability and IL-6 and TNF-α production." | 3.78 | Role of M3 mAChR in in vivo and in vitro models of LPS-induced inflammatory response. ( Chen, HZ; Cui, YY; Hou, LN; Xu, GN; Xu, ZP; Yang, K; Zhang, WH; Zhu, L, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Xu, ZP | 1 |
| Yang, K | 1 |
| Xu, GN | 1 |
| Zhu, L | 1 |
| Hou, LN | 1 |
| Zhang, WH | 1 |
| Chen, HZ | 1 |
| Cui, YY | 1 |
1 other study available for 4-diphenylacetoxy-1,1-dimethylpiperidinium and Pneumonia
| Article | Year |
|---|---|
Role of M3 mAChR in in vivo and in vitro models of LPS-induced inflammatory response.
Topics: Acute Lung Injury; Animals; Atropine; Cell Line; Lipopolysaccharides; Macrophages, Alveolar; Male; M | 2012 |