Page last updated: 2024-10-21

4-diphenylacetoxy-1,1-dimethylpiperidinium and Pain

4-diphenylacetoxy-1,1-dimethylpiperidinium has been researched along with Pain in 4 studies

4-diphenylacetoxy-1,1-dimethylpiperidinium: muscarinic receptor antagonist; RN given refers to parent cpd; do not confuse abbreviation 4-DAMP with a similar cpd which does not contain dimethyl groups
4-DAMP(1+) : A quaternary ammonium salt obtained by formal methylation of the tertiary amino function of 4-diphenylacetoxy-N-methylpiperidine.

Pain: An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS.

Research Excerpts

ExcerptRelevanceReference
"These data indicate for the first time that the clonidine-induced increase in punctuate mechanical threshold is mediated via the activation of all but M2 muscarinic receptor subtypes, and via the activation of alpha4beta2 but not alpha7 nicotinic receptor subtypes in a rodent model for human postoperative pain."7.73Spinal muscarinic and nicotinic subtypes activated by clonidine in postincisional pain. ( Boselli, E; Chassard, D; Duflo, F; Ryvlin, P, 2005)
"These data indicate for the first time that the clonidine-induced increase in punctuate mechanical threshold is mediated via the activation of all but M2 muscarinic receptor subtypes, and via the activation of alpha4beta2 but not alpha7 nicotinic receptor subtypes in a rodent model for human postoperative pain."3.73Spinal muscarinic and nicotinic subtypes activated by clonidine in postincisional pain. ( Boselli, E; Chassard, D; Duflo, F; Ryvlin, P, 2005)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (75.00)29.6817
2010's1 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Sung, SK1
Kim, SJ1
Ahn, TS1
Hong, NR1
Park, HS1
Kwon, YK1
Kim, BJ1
Koga, K1
Honda, K2
Ando, S1
Harasawa, I1
Kamiya, HO1
Takano, Y2
Duflo, F1
Boselli, E1
Ryvlin, P1
Chassard, D1
Harada, A1
Kamiya, H1

Other Studies

4 other studies available for 4-diphenylacetoxy-1,1-dimethylpiperidinium and Pain

ArticleYear
Effects of Dangkwisoo‑san, a traditional herbal medicine for treating pain and blood stagnation, on the pacemaker activities of cultured interstitial cells of Cajal.
    Molecular medicine reports, 2015, Volume: 12, Issue:4

    Topics: Animals; Calcium-Transporting ATPases; Cells, Cultured; Diamines; Female; Gastrointestinal Motility;

2015
Intrathecal clonidine inhibits mechanical allodynia via activation of the spinal muscarinic M1 receptor in streptozotocin-induced diabetic mice.
    European journal of pharmacology, 2004, Nov-28, Volume: 505, Issue:1-3

    Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Analgesics; Animals; Atropine;

2004
Spinal muscarinic and nicotinic subtypes activated by clonidine in postincisional pain.
    Anesthesiology, 2005, Volume: 103, Issue:6

    Topics: Aconitine; Adrenergic alpha-Agonists; Animals; Behavior, Animal; Clonidine; Diamines; Dihydro-beta-E

2005
Involvement of M3 muscarinic receptors of the spinal cord in formalin-induced nociception in mice.
    Brain research, 2000, Mar-17, Volume: 859, Issue:1

    Topics: Acetylcholine; Animals; Atropine; Cholinergic Agents; Cholinesterase Inhibitors; Formaldehyde; Hemic

2000