4-diphenylacetoxy-1,1-dimethylpiperidinium has been researched along with Muscle Contraction in 74 studies
4-diphenylacetoxy-1,1-dimethylpiperidinium: muscarinic receptor antagonist; RN given refers to parent cpd; do not confuse abbreviation 4-DAMP with a similar cpd which does not contain dimethyl groups
4-DAMP(1+) : A quaternary ammonium salt obtained by formal methylation of the tertiary amino function of 4-diphenylacetoxy-N-methylpiperidine.
Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The effect of SS or normal immunoglobulin G (IgG) on smooth muscle (SM) motility was assessed by comparing the amplitude of carbachol (CCh) or electrical field stimulation (EFS) - induced muscle contraction before and after IgG application." | 3.79 | The inhibitory effects of antimuscarinic autoantibodies in the sera of primary Sjogren syndrome patients on the gastrointestinal motility. ( Jackson, MW; Park, K; Park, S, 2013) |
| "Propiverine is a commonly used antimuscarinic drug used as therapy for symptoms of an overactive bladder." | 1.33 | Propiverine and metabolites: differences in binding to muscarinic receptors and in functional models of detrusor contraction. ( Braeter, M; Hakenberg, OW; Kelly, LU; Ravens, U; Waelbroeck, M; Weiss, A; Wuest, M, 2006) |
| "Arecoline is an effective component of areca (betel nuts, a Chinese medicine named pinang or binglang)." | 1.32 | Arecoline excites the colonic smooth muscle motility via M3 receptor in rabbits. ( Chen, LB; Liu, CY; Liu, KJ; Wang, PS; Xie, DP; Zhang, CL, 2004) |
| "(3) Tetrodotoxin (TTX) was tested on the anti-ChE drugs-induced responses." | 1.30 | Contractile and phosphatidylinositol responses of rat trachea to anticholinesterase drugs. ( Hara, T; Iwanaga, S; Makita, T; Shibata, O; Shibata, S; Sumikawa, K; Tsuda, A, 1998) |
| " Oxotremorine generated dose-response curves that were similar in both the circular and longitudinal vectors and intermediate to those previously reported for carbachol and aceclidine." | 1.29 | The effect of muscarinic agonists and selective receptor subtype antagonists on the contractile response of the isolated rhesus monkey ciliary muscle. ( Gabelt, BT; Kaufman, PL; Poyer, JF, 1994) |
| "Atropine was used as a nonselective antagonist." | 1.29 | Functional characterization of muscarinic receptors in murine airways. ( Garssen, J; Gierveld, CM; Nijkamp, FP; Van der Vliet, H; Van Loveren, H, 1993) |
| " All the antagonists shifted the methacholine dose-response curve to the right in a parallel and concentration-dependent fashion, yielding Schild plots with slopes not significantly different from unity." | 1.28 | Characterization of the muscarinic receptor subtype involved in phosphoinositide metabolism in bovine tracheal smooth muscle. ( Elzinga, CR; Meurs, H; Roffel, AF; Zaagsma, J, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (8.11) | 18.7374 |
| 1990's | 32 (43.24) | 18.2507 |
| 2000's | 28 (37.84) | 29.6817 |
| 2010's | 8 (10.81) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Park, K | 1 |
| Park, S | 1 |
| Jackson, MW | 1 |
| Lai, HH | 2 |
| Smith, CP | 2 |
| Munoz, A | 2 |
| Boone, TB | 2 |
| Szigeti, GP | 1 |
| Somogyi, GT | 2 |
| Cuprian-Beltechi, AM | 2 |
| Solanki, P | 2 |
| Teramoto, N | 1 |
| Cunnane, TC | 2 |
| Singh, J | 1 |
| Mehendiratta, V | 1 |
| Del Galdo, F | 1 |
| Jimenez, SA | 1 |
| Cohen, S | 1 |
| DiMarino, AJ | 1 |
| Rattan, S | 1 |
| Moro, C | 1 |
| Uchiyama, J | 1 |
| Chess-Williams, R | 5 |
| Hu, J | 1 |
| Gao, WY | 1 |
| Ma, L | 1 |
| Man, SL | 1 |
| Huang, LQ | 1 |
| Liu, CX | 1 |
| Shahab, N | 1 |
| Kajioka, S | 1 |
| Seki, N | 1 |
| Naito, S | 1 |
| Andersson, M | 1 |
| Aronsson, P | 2 |
| Doufish, D | 1 |
| Lampert, A | 1 |
| Tobin, G | 4 |
| Romano, MR | 1 |
| Lograno, MD | 1 |
| Brown, SM | 1 |
| Koarai, A | 1 |
| Sturton, RG | 1 |
| Nicholson, AG | 1 |
| Barnes, PJ | 1 |
| Donnelly, LE | 1 |
| Sarria, B | 1 |
| Naline, E | 1 |
| Zhang, Y | 1 |
| Cortijo, J | 1 |
| Molimard, M | 1 |
| Moreau, J | 1 |
| Therond, P | 1 |
| Advenier, C | 1 |
| Morcillo, EJ | 1 |
| So, I | 1 |
| Yang, DK | 1 |
| Kim, HJ | 1 |
| Min, KW | 1 |
| Kang, TM | 1 |
| Kim, SJ | 1 |
| Kim, KW | 1 |
| Park, KH | 1 |
| Jeon, JH | 1 |
| Choi, KH | 1 |
| Kim, IG | 1 |
| Saito, M | 1 |
| Shibata, O | 2 |
| Yamaguchi, M | 1 |
| Yoshimura, M | 1 |
| Makita, T | 2 |
| Harada, N | 1 |
| Niwa, M | 1 |
| Sumikawa, K | 2 |
| James, AN | 1 |
| Ryan, JP | 2 |
| Crowell, MD | 1 |
| Parkman, HP | 2 |
| Ehlert, FJ | 3 |
| Hsu, JC | 1 |
| Leung, K | 1 |
| Lee, AG | 1 |
| Shehnaz, D | 1 |
| Griffin, MT | 1 |
| Xie, DP | 1 |
| Chen, LB | 1 |
| Liu, CY | 1 |
| Zhang, CL | 1 |
| Liu, KJ | 1 |
| Wang, PS | 1 |
| Orman, B | 1 |
| Sterin-Borda, L | 1 |
| Reina, S | 1 |
| Borda, ES | 1 |
| Giglio, D | 3 |
| Delbro, DS | 2 |
| Unno, T | 2 |
| Matsuyama, H | 1 |
| Sakamoto, T | 1 |
| Uchiyama, M | 1 |
| Izumi, Y | 1 |
| Okamoto, H | 1 |
| Yamada, M | 2 |
| Wess, J | 2 |
| Komori, S | 2 |
| Forrest, AS | 1 |
| Ordög, T | 1 |
| Sanders, KM | 1 |
| Ng, YK | 1 |
| de Groat, WC | 1 |
| Wu, HY | 1 |
| Wuest, M | 1 |
| Weiss, A | 1 |
| Waelbroeck, M | 1 |
| Braeter, M | 1 |
| Kelly, LU | 1 |
| Hakenberg, OW | 1 |
| Ravens, U | 1 |
| Kitazawa, T | 1 |
| Hashiba, K | 1 |
| Cao, J | 1 |
| Taneike, T | 1 |
| Stevens, LA | 1 |
| Chapple, CR | 4 |
| Eriksson, L | 1 |
| Pfeiffer, JB | 1 |
| Mevissen, M | 1 |
| Steiner, A | 1 |
| Portier, CJ | 1 |
| Meylan, M | 1 |
| Ren, LM | 1 |
| Nakane, T | 1 |
| Chiba, S | 1 |
| Masuda, Y | 1 |
| Yamahara, NS | 2 |
| Tanaka, M | 2 |
| Ryang, S | 1 |
| Kawai, T | 1 |
| Imaizumi, Y | 2 |
| Watanabe, M | 2 |
| Poyer, JF | 1 |
| Gabelt, BT | 1 |
| Kaufman, PL | 1 |
| Lin, CH | 1 |
| Yang, CM | 1 |
| Ko, FN | 1 |
| Wu, YC | 1 |
| Teng, CM | 1 |
| Shiraishi, K | 1 |
| Takayanagi, I | 1 |
| Garssen, J | 1 |
| Van Loveren, H | 1 |
| Gierveld, CM | 1 |
| Van der Vliet, H | 1 |
| Nijkamp, FP | 1 |
| Kerr, PM | 1 |
| Hillier, K | 1 |
| Wallis, RM | 1 |
| Garland, CJ | 1 |
| Watson, N | 1 |
| Reddy, H | 1 |
| Eglen, RM | 2 |
| Tong, YC | 1 |
| Hung, YC | 1 |
| Lin, SN | 1 |
| Cheng, JT | 1 |
| Sawyer, GW | 1 |
| Lai, FM | 1 |
| Cobuzzi, A | 1 |
| Spinelli, W | 1 |
| Preiksaitis, HG | 1 |
| Laurier, LG | 1 |
| Inadome, A | 1 |
| Yoshida, M | 1 |
| Takahashi, W | 1 |
| Yono, M | 1 |
| Seshita, H | 1 |
| Miyamoto, Y | 1 |
| Kawano, T | 1 |
| Ueda, S | 1 |
| Tsuda, A | 1 |
| Iwanaga, S | 1 |
| Hara, T | 1 |
| Shibata, S | 1 |
| Braverman, A | 1 |
| Legos, J | 1 |
| Young, W | 1 |
| Luthin, G | 1 |
| Ruggieri, M | 1 |
| Thomas, EA | 1 |
| Krichevsky, VP | 1 |
| Pagala, MK | 1 |
| Vaydovsky, I | 1 |
| Damer, V | 1 |
| Wise, GJ | 1 |
| Pagano, AP | 1 |
| Braverman, AS | 1 |
| Ruggieri, MR | 1 |
| Preuss, JM | 1 |
| Goldie, RG | 1 |
| Shen, S | 1 |
| Huang, Y | 1 |
| Bourreau, JP | 1 |
| Yamanishi, T | 3 |
| Yasuda, K | 3 |
| Sellers, DJ | 1 |
| Couldwell, C | 1 |
| Kwon, SC | 1 |
| Kadota, H | 1 |
| Kuwahara, M | 1 |
| Nishibata, R | 1 |
| Mikami, H | 1 |
| Tsubone, H | 1 |
| Choppin, A | 1 |
| Recanatini, M | 1 |
| Minarini, A | 1 |
| Melchiorre, C | 1 |
| Budriesi, R | 1 |
| Bolognesi, ML | 1 |
| Yu, M | 1 |
| Robinson, NE | 1 |
| Wang, Z | 1 |
| Derksen, FJ | 1 |
| Mahesh, VK | 1 |
| Nunan, LM | 1 |
| Halonen, M | 1 |
| Yamamura, HI | 1 |
| Palmer, JD | 1 |
| Bloom, JW | 1 |
| Angeli, P | 1 |
| Brasili, L | 1 |
| Cingolani, ML | 1 |
| Marucci, G | 1 |
| Pigini, P | 1 |
| Tonnini, MC | 1 |
| Itabashi, S | 1 |
| Aikawa, T | 1 |
| Sekizawa, K | 1 |
| Ohrui, T | 1 |
| Sasaki, H | 1 |
| Takishima, T | 1 |
| Rivera, L | 1 |
| Prieto, D | 1 |
| Hernández, M | 1 |
| Benedito, S | 1 |
| García-Sacristán, A | 1 |
| Barocelli, E | 1 |
| Morini, G | 1 |
| Ballabeni, V | 1 |
| Lavezzo, A | 1 |
| Impicciatore, M | 1 |
| Roffel, AF | 2 |
| Elzinga, CR | 2 |
| Zaagsma, J | 2 |
| Meurs, H | 1 |
| Barlow, RB | 2 |
| Holdup, DW | 1 |
| Harris, G | 1 |
| Veale, MA | 1 |
| Williams, A | 1 |
| Brichant, JF | 1 |
| Warner, DO | 1 |
| Gunst, SJ | 2 |
| Rehder, K | 1 |
| Stropp, JQ | 1 |
| Flavahan, NA | 1 |
| Marrion, NV | 1 |
| Smart, TG | 1 |
| Marsh, SJ | 1 |
| Brown, DA | 1 |
| Gilbert, RJ | 1 |
| Dodds, WJ | 1 |
| Tomomasa, T | 1 |
| Hyman, PE | 1 |
| Hsu, CT | 1 |
| Jing, J | 1 |
| Snape, WJ | 1 |
| Grider, JR | 1 |
| Bitar, KN | 1 |
| Makhlouf, GM | 1 |
| Shepherd, MK | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Precision Medicine in Systemic Sclerosis Gastrointestinal Disease: Evaluating Imaging and Stool Biomarkers for Differentiating Disease Stages and Treatment Responses[NCT04630782] | 70 participants (Anticipated) | Observational | 2020-04-09 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for 4-diphenylacetoxy-1,1-dimethylpiperidinium and Muscle Contraction
| Article | Year |
|---|---|
Functional role of M2 muscarinic receptors in the guinea pig ileum.
Topics: Animals; Colforsin; Cyclic AMP; Guinea Pigs; Heart; Histamine; Ileum; Muscarinic Antagonists; Muscle | 1995 |
73 other studies available for 4-diphenylacetoxy-1,1-dimethylpiperidinium and Muscle Contraction
| Article | Year |
|---|---|
The inhibitory effects of antimuscarinic autoantibodies in the sera of primary Sjogren syndrome patients on the gastrointestinal motility.
Topics: Animals; Autoantibodies; Carbachol; Cholinergic Agonists; Colon; Diamines; Dose-Response Relationshi | 2013 |
Activation of cholinergic receptors blocks non-adrenergic non-cholinergic contractions in the rat urinary bladder.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 2008 |
High spatial resolution studies of muscarinic neuroeffector junctions in mouse isolated vas deferens.
Topics: Acetylcholine; Adrenergic alpha-2 Receptor Antagonists; Age Factors; Animals; Calcium; Cholinesteras | 2009 |
Immunoglobulins from scleroderma patients inhibit the muscarinic receptor activation in internal anal sphincter smooth muscle cells.
Topics: Adrenergic alpha-Agonists; Adult; Aged; Aged, 80 and over; Anal Canal; Animals; Autoantibodies; Benz | 2009 |
Plasticity of non-adrenergic non-cholinergic bladder contractions in rats after chronic spinal cord injury.
Topics: Acetylcholine; Adenosine Triphosphate; Animals; Carbachol; Cholinergic Agonists; Female; Muscarinic | 2011 |
Urothelial/lamina propria spontaneous activity and the role of M3 muscarinic receptors in mediating rate responses to stretch and carbachol.
Topics: Animals; Atropine; Benzhydryl Compounds; Benzofurans; Carbachol; Cresols; Diamines; Mandelic Acids; | 2011 |
Activation of M3 muscarinic receptor and Ca²⁺ influx by crude fraction from Crotonis Fructus in isolated rabbit jejunum.
Topics: Animals; Atropine; Calcium; Calcium Channel Blockers; Croton; Female; Fruit; In Vitro Techniques; Je | 2012 |
Functional role of muscarinic receptor subtypes in calcium sensitization and their contribution to rho-kinase and protein kinase C pathways in contraction of human detrusor smooth muscle.
Topics: Amides; Calcium; Carbachol; Enzyme Inhibitors; Humans; In Vitro Techniques; Indoles; Maleimides; Mus | 2012 |
Muscarinic receptor subtypes involved in urothelium-derived relaxatory effects in the inflamed rat urinary bladder.
Topics: Animals; Carbachol; Cyclophosphamide; Cystitis; Dose-Response Relationship, Drug; Enzyme Inhibitors; | 2012 |
Signaling cross-talk between cannabinoid and muscarinic systems actives Rho-kinase and increases the contractile responses of the bovine ciliary muscle.
Topics: Animals; Arachidonic Acids; Cannabinoid Receptor Agonists; Cannabinoid Receptor Antagonists; Carbach | 2013 |
A role for M(2) and M(3) muscarinic receptors in the contraction of rat and human small airways.
Topics: Animals; Carbachol; Cholinergic Agonists; Humans; In Vitro Techniques; Lung; Muscarinic Antagonists; | 2013 |
Muscarinic M2 receptors in acetylcholine-isoproterenol functional antagonism in human isolated bronchus.
Topics: Acetylcholine; Bronchi; Colforsin; Cyclic AMP; Humans; In Vitro Techniques; Isoproterenol; Lung Neop | 2002 |
Five subtypes of muscarinic receptors are expressed in gastric smooth muscles of guinea pig.
Topics: Animals; Base Sequence; Carbachol; Cations; Cholinergic Agonists; Dose-Response Relationship, Drug; | 2003 |
Metoclopramide causes airway smooth muscle relaxation through inhibition of muscarinic M3 receptor in the rat trachea.
Topics: Animals; Antiemetics; Carbachol; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Male; Metoclopra | 2004 |
Regional gastric contractility alterations in a diabetic gastroparesis mouse model: effects of cholinergic and serotoninergic stimulation.
Topics: Animals; Bethanechol; Cholinergic Agonists; Diabetes Mellitus, Experimental; Dose-Response Relations | 2004 |
Comparison of the antimuscarinic action of p-fluorohexahydrosiladifenidol in ileal and tracheal smooth muscle.
Topics: Animals; Atropine; Cattle; Guinea Pigs; Histamine Antagonists; Hydrolysis; Ileum; In Vitro Technique | 2005 |
Arecoline excites the colonic smooth muscle motility via M3 receptor in rabbits.
Topics: Animals; Arecoline; Atropine; Colon; Dose-Response Relationship, Drug; Female; Ganglionic Stimulants | 2004 |
Neuronal nitric oxide synthase activity in rat urinary bladder detrusor: participation in M3 and M4 muscarinic receptor function.
Topics: Animals; Carbachol; Cholinergic Agonists; Cyclic GMP; Dose-Response Relationship, Drug; In Vitro Tec | 2005 |
Postjunctional modulation by muscarinic M2 receptors of responses to electrical field stimulation of rat detrusor muscle preparations.
Topics: Animals; Diamines; Electric Stimulation; In Vitro Techniques; Muscarinic Antagonists; Muscle Contrac | 2005 |
M(2) and M(3) muscarinic receptor-mediated contractions in longitudinal smooth muscle of the ileum studied with receptor knockout mice.
Topics: Animals; Calcium Channel Blockers; Carbachol; Cholinergic Agonists; Diamines; Female; Ileum; In Vitr | 2005 |
Neural regulation of slow-wave frequency in the murine gastric antrum.
Topics: Acetylcholine; Androstenes; Animals; Atropine; Benzamides; Benzimidazoles; Carbachol; Electric Stimu | 2006 |
Muscarinic regulation of neonatal rat bladder spontaneous contractions.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 2006 |
Propiverine and metabolites: differences in binding to muscarinic receptors and in functional models of detrusor contraction.
Topics: Animals; Benzilates; Binding, Competitive; Calcium; Carbachol; Cell Line; Cells, Cultured; CHO Cells | 2006 |
Functional roles of muscarinic M2 and M3 receptors in mouse stomach motility: studies with muscarinic receptor knockout mice.
Topics: Animals; Carbachol; Cholinergic Agonists; Dose-Response Relationship, Drug; Electric Stimulation; En | 2007 |
Human idiopathic and neurogenic overactive bladders and the role of M2 muscarinic receptors in contraction.
Topics: Adult; Aged; Benzofurans; Carbachol; Diamines; Dose-Response Relationship, Drug; Female; Humans; In | 2007 |
In vitro characterization of parasympathetic and sympathetic responses in cyclophosphamide-induced cystitis in the rat.
Topics: Adenosine Triphosphate; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Cyclopho | 2007 |
In vitro effects of bethanechol on specimens of intestinal smooth muscle obtained from the duodenum and jejunum of healthy dairy cows.
Topics: Animals; Bethanechol; Cattle; Dairying; Dose-Response Relationship, Drug; Duodenum; Female; In Vitro | 2007 |
Cholinergic innervation of the guinea-pig isolated vas deferens.
Topics: Acetylcholine; Adrenergic alpha-Antagonists; Animals; Bretylium Compounds; Calcium; Cholinesterase I | 2007 |
Muscarinic receptor subtypes mediating vasodilation and vasoconstriction in isolated, perfused simian coronary arteries.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Acetylcholine; Animals; Corona | 1993 |
Characterization of muscarinic receptors mediating relaxation and contraction in the rat iris dilator muscle.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Acetylcholine; Alkaloids; Anim | 1995 |
The effect of muscarinic agonists and selective receptor subtype antagonists on the contractile response of the isolated rhesus monkey ciliary muscle.
Topics: Animals; Carbachol; Ciliary Body; Dose-Response Relationship, Drug; In Vitro Techniques; Macaca mula | 1994 |
Pertussis toxin-sensitive muscarinic relaxation in the rat iris dilator muscle.
Topics: Acetylcholine; Alkaloids; Animals; Atropine; Diamines; Dose-Response Relationship, Drug; Furans; GTP | 1995 |
Antimuscarinic action of liriodenine, isolated from Fissistigma glaucescens, in canine tracheal smooth muscle.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Antineoplastic Agents, Phytogenic; Aporphin | 1994 |
Subtype of muscarinic receptors mediating relaxation and contraction in the rat iris dilator smooth muscle.
Topics: Alkaloids; Animals; Atropine; Carbachol; Furans; In Vitro Techniques; Iris; Male; Muscle Contraction | 1993 |
Functional characterization of muscarinic receptors in murine airways.
Topics: Administration, Inhalation; Airway Resistance; Animals; Atropine; Bronchi; Electric Stimulation; In | 1993 |
Characterization of muscarinic receptors mediating contractions of circular and longitudinal muscle of human isolated colon.
Topics: Alkaloids; Atropine; Carbachol; Carcinoma; Colon; Colonic Neoplasms; Dose-Response Relationship, Dru | 1995 |
Pharmacological characterization of the muscarinic receptors mediating contraction of canine saphenous vein.
Topics: Animals; Dioxolanes; Dogs; Female; In Vitro Techniques; Muscarinic Agonists; Muscle Contraction; Mus | 1995 |
Pharmacological characterization of the muscarinic receptor subtypes responsible for the contractile response in the rat urinary bladder.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Acetylcholine; Analysis of Var | 1997 |
Contractile roles of the M2 and M3 muscarinic receptors in the guinea pig colon.
Topics: Animals; Colforsin; Colon; Cyclic AMP; Guinea Pigs; Histamine; In Vitro Techniques; Isoproterenol; M | 1998 |
Characterization of muscarinic receptors mediating the contraction of the urinary detrusor muscle in cynomolgus monkeys and guinea pigs.
Topics: Animals; Carbachol; Diamines; Female; Guinea Pigs; Macaca fascicularis; Male; Muscarinic Agonists; M | 1998 |
Pharmacological and molecular characterization of muscarinic receptors in cat esophageal smooth muscle.
Topics: Amino Acid Sequence; Animals; Base Sequence; Carbachol; Cats; Dioxoles; Electric Stimulation; Esopha | 1998 |
Prejunctional muscarinic receptors modulating acetylcholine release in rabbit detrusor smooth muscles.
Topics: Acetylcholine; Animals; Chromatography, High Pressure Liquid; Culture Techniques; Diamines; Female; | 1998 |
Contractile and phosphatidylinositol responses of rat trachea to anticholinesterase drugs.
Topics: Animals; Carbachol; Cholinergic Agonists; Cholinesterase Inhibitors; Dimethylphenylpiperazinium Iodi | 1998 |
M2 receptors in genito-urinary smooth muscle pathology.
Topics: Animals; Binding Sites; Carbachol; Diamines; Dose-Response Relationship, Drug; Female; Hypertrophy; | 1999 |
Function of M3 muscarinic receptors in the rat urinary bladder following partial outlet obstruction.
Topics: Animals; Carbachol; Dose-Response Relationship, Drug; Male; Muscarinic Agonists; Muscarinic Antagoni | 1999 |
Subtypes of muscarinic receptors regulating gallbladder cholinergic contractions.
Topics: Acetylcholine; Animals; Atropine; Diamines; Electric Stimulation; Gallbladder; Guinea Pigs; Hexameth | 1999 |
Selective alkylation of rat urinary bladder muscarinic receptors with 4-DAMP mustard reveals a contractile function for the M2 muscarinic receptor.
Topics: Alkylation; Animals; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Piperidines; Rats; | 1999 |
Muscarinic cholinoceptor subtypes mediating tracheal smooth muscle contraction and inositol phosphate generation in guinea pig and rat.
Topics: Animals; Atropine; Diamines; Guinea Pigs; In Vitro Techniques; Inositol Phosphates; Male; Muscarinic | 1999 |
Efficacy of muscarinic stimulation and mode of excitation-contraction coupling in bovine trachealis muscle.
Topics: Acetylcholine; Animals; Calcium; Cattle; Cromakalim; Diamines; Dose-Response Relationship, Drug; Dru | 2000 |
The role of M(2)-muscarinic receptors in mediating contraction of the pig urinary bladder in vitro.
Topics: Animals; Benzofurans; Binding, Competitive; Carbachol; Diamines; Dose-Response Relationship, Drug; F | 2000 |
M3 muscarinic receptors but not M2 mediate contraction of the porcine detrusor muscle in vitro.
Topics: Animals; Carbachol; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Muscarinic Antago | 2000 |
Mechanisms of acetylcholine-induced vasorelaxation in high K+-stimulated rabbit renal arteries.
Topics: Acetylcholine; Animals; Atropine; Calcium; Calcium Channel Blockers; Cations, Monovalent; Endotheliu | 2001 |
Effect of M2 and M3 muscarinic receptors on airway responsiveness to carbachol in bronchial-hypersensitive (BHS) and bronchial-hyposensitive (BHR) guinea pigs.
Topics: Animals; Bronchial Hyperreactivity; Carbachol; Diamines; Gene Expression; Guinea Pigs; Lung; Male; M | 2001 |
Pharmacological characterization of muscarinic receptors in mouse isolated urinary bladder smooth muscle.
Topics: Acetylcholine; Animals; Carbachol; Diamines; Dioxolanes; Dose-Response Relationship, Drug; In Vitro | 2001 |
On the functional role of muscarinic M2 receptors in cholinergic and purinergic responses in the rat urinary bladder.
Topics: 2-Chloroadenosine; Adenosine; Adenosine Triphosphate; Animals; Carbachol; Diamines; Dose-Response Re | 2001 |
The role of M2 muscarinic receptor subtypes in mediating contraction of the pig bladder base after cyclic adenosine monophosphate elevation and/or selective M3 inactivation.
Topics: Animals; Cyclic AMP; Diamines; Female; In Vitro Techniques; Isoproterenol; Muscle Contraction; Muscl | 2002 |
Affinity and selectivity at M2 and M3 muscarinic receptor subtypes of cyclic and oxygenated analogues of 4-DAMP.
Topics: Animals; Chemical Phenomena; Chemistry, Physical; Electric Stimulation; Guinea Pigs; In Vitro Techni | 1992 |
Muscarinic receptor subtypes in equine tracheal smooth muscle.
Topics: Acetylcholine; Animals; Electric Stimulation; Gallamine Triethiodide; Horses; In Vitro Techniques; M | 1992 |
A minority of muscarinic receptors mediate rabbit tracheal smooth muscle contraction.
Topics: Animals; Atropine; Female; Male; Methacholine Chloride; Muscle Contraction; Muscle, Smooth; Myocardi | 1992 |
Pharmacological characterization of muscarinic receptor subtypes in rabbit isolated tissue preparations.
Topics: Animals; Aorta, Thoracic; Atropine; Diamines; Jejunum; Male; Muscarinic Antagonists; Muscle Contract | 1991 |
Pre- and postjunctional muscarinic receptor subtypes in dog airways.
Topics: Acetylcholine; Animals; Atropine; Bronchi; Dogs; Dose-Response Relationship, Drug; Electric Stimulat | 1991 |
Distribution and function of cholinergic receptors in the sheep detrusor muscle.
Topics: Acetylcholine; Acetylcholinesterase; Animals; Atropine; Carbachol; Cholinesterase Inhibitors; Gangli | 1991 |
Effects of two new pirenzepine analogs on the contractile response of the guinea-pig oesophageal muscularis mucosae to acetylcholine, bethanechol, histamine and high potassium.
Topics: Acetylcholine; Animals; Atropine; Benzodiazepinones; Bethanechol; Bethanechol Compounds; Esophagus; | 1990 |
Muscarinic M3 receptors mediate contraction of human central and peripheral airway smooth muscle.
Topics: Bronchi; Humans; In Vitro Techniques; Ipratropium; Muscle Contraction; Muscle, Smooth; Parasympathol | 1990 |
Characterization of the muscarinic receptor subtype involved in phosphoinositide metabolism in bovine tracheal smooth muscle.
Topics: Animals; Cattle; In Vitro Techniques; Inositol Phosphates; Methacholine Compounds; Muscle Contractio | 1990 |
Effects of chain-length and unsaturation on affinity and selectivity at muscarinic receptors.
Topics: Animals; Chemical Phenomena; Chemistry; Guinea Pigs; Ileum; In Vitro Techniques; Muscle Contraction; | 1990 |
Muscarinic receptor subtypes in canine trachea.
Topics: Acetylcholine; Animals; Dogs; Electric Stimulation; In Vitro Techniques; Muscle Contraction; Muscle, | 1990 |
Muscarinic receptor reserve and beta-adrenergic sensitivity in tracheal smooth muscle.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Acetylcholine; Animals; Dogs; | 1989 |
Muscarinic suppression of the M-current in the rat sympathetic ganglion is mediated by receptors of the M1-subtype.
Topics: Animals; Calcium; Gallamine Triethiodide; Ganglia, Spinal; Ganglia, Sympathetic; Ileum; In Vitro Tec | 1989 |
Effect of selective muscarinic antagonists on peristaltic contractions in opossum smooth muscle.
Topics: Animals; Atropine; Benzodiazepinones; Bethanechol; Bethanechol Compounds; Dose-Response Relationship | 1986 |
Development of the muscarinic receptor in rabbit gastric smooth muscle.
Topics: Animals; Animals, Newborn; Atropine; Bethanechol; Bethanechol Compounds; Dose-Response Relationship, | 1988 |
Identification of muscarinic M2 receptors on single muscle cells of the human and guinea pig intestine.
Topics: Acetylcholine; Animals; Atropine; Guinea Pigs; Humans; Jejunum; Muscle Contraction; Muscle, Smooth; | 1987 |
A search for selective antagonists at M2 muscarinic receptors.
Topics: Animals; Atrial Function; Carbachol; Chemical Phenomena; Chemistry; Guinea Pigs; Heart Rate; Ileum; | 1985 |