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4-diphenylacetoxy-1,1-dimethylpiperidinium and Injury, Ischemia-Reperfusion

4-diphenylacetoxy-1,1-dimethylpiperidinium has been researched along with Injury, Ischemia-Reperfusion in 2 studies

4-diphenylacetoxy-1,1-dimethylpiperidinium: muscarinic receptor antagonist; RN given refers to parent cpd; do not confuse abbreviation 4-DAMP with a similar cpd which does not contain dimethyl groups
4-DAMP(1+) : A quaternary ammonium salt obtained by formal methylation of the tertiary amino function of 4-diphenylacetoxy-N-methylpiperidine.

Research Excerpts

ExcerptRelevanceReference
"Choline treatment attenuated I/R-induced vascular dysfunction, blocked elevations in the levels of reactive oxygen species (ROS) and decreased the up-regulated expression of oxidised CaMKII and phosphorylated CaMKII."1.42Activation of M3 cholinoceptors attenuates vascular injury after ischaemia/reperfusion by inhibiting the Ca2+/calmodulin-dependent protein kinase II pathway. ( Bi, XY; He, X; Lu, XZ; Xu, M; Yu, XJ; Zang, WJ; Zhao, M; Zhao, ZH, 2015)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lu, XZ1
Bi, XY1
He, X2
Zhao, M2
Xu, M2
Yu, XJ1
Zhao, ZH1
Zang, WJ1
Bi, X1
Yu, X1
Lu, X1
Zang, W1

Other Studies

2 other studies available for 4-diphenylacetoxy-1,1-dimethylpiperidinium and Injury, Ischemia-Reperfusion

ArticleYear
Activation of M3 cholinoceptors attenuates vascular injury after ischaemia/reperfusion by inhibiting the Ca2+/calmodulin-dependent protein kinase II pathway.
    British journal of pharmacology, 2015, Volume: 172, Issue:23

    Topics: Administration, Intravenous; Animals; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Choline; C

2015
Acetylcholine ameliorates endoplasmic reticulum stress in endothelial cells after hypoxia/reoxygenation via M3 AChR-AMPK signaling.
    Cell cycle (Georgetown, Tex.), 2015, Aug-03, Volume: 14, Issue:15

    Topics: Acetylcholine; AMP-Activated Protein Kinases; Apoptosis; Caspase 12; Cell Hypoxia; Cell Line; DNA Nu

2015