4-diphenylacetoxy-1,1-dimethylpiperidinium has been researched along with Dementia Praecox in 3 studies
4-diphenylacetoxy-1,1-dimethylpiperidinium: muscarinic receptor antagonist; RN given refers to parent cpd; do not confuse abbreviation 4-DAMP with a similar cpd which does not contain dimethyl groups
4-DAMP(1+) : A quaternary ammonium salt obtained by formal methylation of the tertiary amino function of 4-diphenylacetoxy-N-methylpiperidine.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Having separated a sub-group of people with schizophrenia based on a marked loss of cortical [(3)H]pirenzepine binding (MRDS); we wished to determine if MRDS had lower levels of [(3)H]pirenzepine and other muscarinic receptor antagonist binding to the striatum and if this was due to loss of pre- or post-synaptic neurons or glia measured using surrogate markers (25 kilodalton synaptosomal-associated protein (SNAP 25), postsynaptic density protein 95 (PSD 95), glial fibrillary acidic protein (GFAP) 41/43) of cell number." | 3.81 | Changes in cholinergic and glutamatergic markers in the striatum from a sub-set of subjects with schizophrenia. ( Chen, WJ; Dean, B; Lai, CY; Scarr, E; Thomas, N, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Seo, MS | 1 |
| Scarr, E | 3 |
| Dean, B | 3 |
| Thomas, N | 1 |
| Lai, CY | 1 |
| Chen, WJ | 1 |
| Soulby, A | 1 |
| Evin, GM | 1 |
3 other studies available for 4-diphenylacetoxy-1,1-dimethylpiperidinium and Dementia Praecox
| Article | Year |
|---|---|
An investigation of the factors that regulate muscarinic receptor expression in schizophrenia.
Topics: Adult; Blotting, Western; Brain; Cohort Studies; Humans; Middle Aged; Piperidines; Pirenzepine; Poly | 2014 |
Changes in cholinergic and glutamatergic markers in the striatum from a sub-set of subjects with schizophrenia.
Topics: Autoradiography; Blotting, Western; Corpus Striatum; Disks Large Homolog 4 Protein; Female; Glial Fi | 2015 |
Levels of [(3)H]pirenzepine binding in Brodmann's area 6 from subjects with schizophrenia is not associated with changes in the transcription factor SP1 or BACE1.
Topics: Adult; Aged; Autoradiography; Binding Sites; Cathepsin B; Cerebral Cortex; Female; Humans; Male; Mid | 2008 |