4-diphenylacetoxy-1,1-dimethylpiperidinium has been researched along with Arrhythmias, Cardiac in 4 studies
4-diphenylacetoxy-1,1-dimethylpiperidinium: muscarinic receptor antagonist; RN given refers to parent cpd; do not confuse abbreviation 4-DAMP with a similar cpd which does not contain dimethyl groups
4-DAMP(1+) : A quaternary ammonium salt obtained by formal methylation of the tertiary amino function of 4-diphenylacetoxy-N-methylpiperidine.
Arrhythmias, Cardiac: Any disturbances of the normal rhythmic beating of the heart or MYOCARDIAL CONTRACTION. Cardiac arrhythmias can be classified by the abnormalities in HEART RATE, disorders of electrical impulse generation, or impulse conduction.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study was designed to evaluate the effects of pilocarpine and explore the underlying ionic mechanism, using both aconitine-induced rat and ouabain-induced guinea pig arrhythmia models." | 3.75 | The antiarrhythmic effect and possible ionic mechanisms of pilocarpine on animal models. ( Chen, LP; Chen, W; Han, HM; Li, DL; Liu, Y; Pan, ZY; Qi, HP; Sun, HL; Wang, LY; Xie, J; Zhao, WM, 2009) |
| "It is well known that choline has protective effects on ischemic arrhythmias." | 3.74 | Choline produces antiarrhythmic actions in animal models by cardiac M3 receptors: improvement of intracellular Ca2+ handling as a common mechanism. ( Du, ZM; Gao, Y; Li, DL; Liu, Y; Lu, YJ; Sun, HL; Wang, LY; Wang, YP; Yang, BF, 2008) |
| "In acute ischemic model of rats, the M3 receptor antagonist 4-diphenylacetoxy-N-methylpiperidine-methiodide (4DAMP) increased the occurrence of arrhythmias, and the M3 receptor agonist choline suppressed the onset and the development of arrhythmias (P < 0." | 3.73 | M3-R/IK(M3)--a new target of antiarrhythmic agents. ( Dong, DL; Jiao, JD; Liu, Y; Wang, HZ; Xu, CQ; Yang, BF, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, GX | 1 |
| Pan, GP | 1 |
| Sun, LH | 1 |
| Zhang, YL | 1 |
| Yang, BF | 3 |
| Wang, L | 1 |
| Liu, Y | 4 |
| Sun, HL | 2 |
| Li, DL | 2 |
| Wang, LY | 2 |
| Gao, Y | 1 |
| Wang, YP | 1 |
| Du, ZM | 1 |
| Lu, YJ | 1 |
| Zhao, WM | 1 |
| Qi, HP | 1 |
| Chen, W | 1 |
| Xie, J | 1 |
| Pan, ZY | 1 |
| Han, HM | 1 |
| Chen, LP | 1 |
| Xu, CQ | 1 |
| Jiao, JD | 1 |
| Wang, HZ | 1 |
| Dong, DL | 1 |
4 other studies available for 4-diphenylacetoxy-1,1-dimethylpiperidinium and Arrhythmias, Cardiac
| Article | Year |
|---|---|
[Role of ventricular M3 receptor in arrhythmia resulted from cerebral-cardiac syndrome].
Topics: Animals; Arrhythmias, Cardiac; Calcium; Choline; Electrocardiography; Heart Ventricles; Infarction, | 2008 |
Choline produces antiarrhythmic actions in animal models by cardiac M3 receptors: improvement of intracellular Ca2+ handling as a common mechanism.
Topics: Aconitine; Animals; Arrhythmias, Cardiac; Calcium; Choline; Disease Models, Animal; Female; Guinea P | 2008 |
The antiarrhythmic effect and possible ionic mechanisms of pilocarpine on animal models.
Topics: Aconitine; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Calcium; Disease Models, Animal; F | 2009 |
M3-R/IK(M3)--a new target of antiarrhythmic agents.
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cell Separation; Choline; Guinea Pigs; Heart | 2005 |