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4-diphenylacetoxy-1,1-dimethylpiperidinium and Arrhythmia

4-diphenylacetoxy-1,1-dimethylpiperidinium has been researched along with Arrhythmia in 4 studies

4-diphenylacetoxy-1,1-dimethylpiperidinium: muscarinic receptor antagonist; RN given refers to parent cpd; do not confuse abbreviation 4-DAMP with a similar cpd which does not contain dimethyl groups
4-DAMP(1+) : A quaternary ammonium salt obtained by formal methylation of the tertiary amino function of 4-diphenylacetoxy-N-methylpiperidine.

Research Excerpts

ExcerptRelevanceReference
"This study was designed to evaluate the effects of pilocarpine and explore the underlying ionic mechanism, using both aconitine-induced rat and ouabain-induced guinea pig arrhythmia models."3.75The antiarrhythmic effect and possible ionic mechanisms of pilocarpine on animal models. ( Chen, LP; Chen, W; Han, HM; Li, DL; Liu, Y; Pan, ZY; Qi, HP; Sun, HL; Wang, LY; Xie, J; Zhao, WM, 2009)
"It is well known that choline has protective effects on ischemic arrhythmias."3.74Choline produces antiarrhythmic actions in animal models by cardiac M3 receptors: improvement of intracellular Ca2+ handling as a common mechanism. ( Du, ZM; Gao, Y; Li, DL; Liu, Y; Lu, YJ; Sun, HL; Wang, LY; Wang, YP; Yang, BF, 2008)
"In acute ischemic model of rats, the M3 receptor antagonist 4-diphenylacetoxy-N-methylpiperidine-methiodide (4DAMP) increased the occurrence of arrhythmias, and the M3 receptor agonist choline suppressed the onset and the development of arrhythmias (P < 0."3.73M3-R/IK(M3)--a new target of antiarrhythmic agents. ( Dong, DL; Jiao, JD; Liu, Y; Wang, HZ; Xu, CQ; Yang, BF, 2005)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Zhang, GX1
Pan, GP1
Sun, LH1
Zhang, YL1
Yang, BF3
Wang, L1
Liu, Y4
Sun, HL2
Li, DL2
Wang, LY2
Gao, Y1
Wang, YP1
Du, ZM1
Lu, YJ1
Zhao, WM1
Qi, HP1
Chen, W1
Xie, J1
Pan, ZY1
Han, HM1
Chen, LP1
Xu, CQ1
Jiao, JD1
Wang, HZ1
Dong, DL1

Other Studies

4 other studies available for 4-diphenylacetoxy-1,1-dimethylpiperidinium and Arrhythmia

ArticleYear
[Role of ventricular M3 receptor in arrhythmia resulted from cerebral-cardiac syndrome].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2008, Volume: 43, Issue:8

    Topics: Animals; Arrhythmias, Cardiac; Calcium; Choline; Electrocardiography; Heart Ventricles; Infarction,

2008
Choline produces antiarrhythmic actions in animal models by cardiac M3 receptors: improvement of intracellular Ca2+ handling as a common mechanism.
    Canadian journal of physiology and pharmacology, 2008, Volume: 86, Issue:12

    Topics: Aconitine; Animals; Arrhythmias, Cardiac; Calcium; Choline; Disease Models, Animal; Female; Guinea P

2008
The antiarrhythmic effect and possible ionic mechanisms of pilocarpine on animal models.
    Journal of cardiovascular pharmacology and therapeutics, 2009, Volume: 14, Issue:3

    Topics: Aconitine; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Calcium; Disease Models, Animal; F

2009
M3-R/IK(M3)--a new target of antiarrhythmic agents.
    Yao xue xue bao = Acta pharmaceutica Sinica, 2005, Volume: 40, Issue:1

    Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cell Separation; Choline; Guinea Pigs; Heart

2005