Page last updated: 2024-10-25

4-cresol and Renal Insufficiency

4-cresol has been researched along with Renal Insufficiency in 4 studies

4-cresol: RN given refers to parent cpd
p-cresol : A cresol that consists of toluene substituted by a hydroxy group at position 4. It is a metabolite of aromatic amino acid metabolism produced by intestinal microflora in humans and animals.

Renal Insufficiency: Conditions in which the KIDNEYS perform below the normal level in the ability to remove wastes, concentrate URINE, and maintain ELECTROLYTE BALANCE; BLOOD PRESSURE; and CALCIUM metabolism. Renal insufficiency can be classified by the degree of kidney damage (as measured by the level of PROTEINURIA) and reduction in GLOMERULAR FILTRATION RATE.

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (25.00)18.2507
2000's3 (75.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
de Loor, H1
Bammens, B2
Evenepoel, P2
De Preter, V1
Verbeke, K2
Keuleers, H1
Vanrenterghem, Y1
Ketteler, M1
De Smet, R1
Glorieux, G1
Hsu, C1
Vanholder, R1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Study on the Effect of Flucloxacillin on the Serum Level of P-cresol in Peritoneal Dialysis Patients[NCT00433342]Phase 19 participants (Actual)Interventional2006-03-31Terminated
A Multicentric Observational Trial on Protein Bound Uremic Toxins in Nocturnal Hemodialysis[NCT00417339]38 participants (Actual)Observational2006-12-31Completed
A Multicentric Observational Study on the Removal of Protein-Bound Uremic Retention Solutes in Nocturnal Hemodialysis: A Cross-Sectional Analysis[NCT00417105]120 participants (Actual)Observational2006-12-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for 4-cresol and Renal Insufficiency

ArticleYear
p-cresol and uric acid: two old uremic toxins revisited.
    Kidney international. Supplement, 1997, Volume: 62

    Topics: Cresols; Humans; In Vitro Techniques; Kidney; Renal Insufficiency; Toxins, Biological; Uremia; Uric

1997

Other Studies

3 other studies available for 4-cresol and Renal Insufficiency

ArticleYear
Gas chromatographic-mass spectrometric analysis for measurement of p-cresol and its conjugated metabolites in uremic and normal serum.
    Clinical chemistry, 2005, Volume: 51, Issue:8

    Topics: Adult; Aged; Cresols; Gas Chromatography-Mass Spectrometry; Glucuronates; Glucuronides; Heating; Hum

2005
Free serum concentrations of the protein-bound retention solute p-cresol predict mortality in hemodialysis patients.
    Kidney international, 2006, Volume: 69, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Cohort Studies; Confidence Intervals; Creatinine; Cresols; Disease P

2006
Free serum concentrations of the protein-bound retention solute p-cresol predict mortality in hemodialysis patients.
    Kidney international, 2006, Volume: 69, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Cohort Studies; Confidence Intervals; Creatinine; Cresols; Disease P

2006
Free serum concentrations of the protein-bound retention solute p-cresol predict mortality in hemodialysis patients.
    Kidney international, 2006, Volume: 69, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Cohort Studies; Confidence Intervals; Creatinine; Cresols; Disease P

2006
Free serum concentrations of the protein-bound retention solute p-cresol predict mortality in hemodialysis patients.
    Kidney international, 2006, Volume: 69, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Cohort Studies; Confidence Intervals; Creatinine; Cresols; Disease P

2006
Free serum concentrations of the protein-bound retention solute p-cresol predict mortality in hemodialysis patients.
    Kidney international, 2006, Volume: 69, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Cohort Studies; Confidence Intervals; Creatinine; Cresols; Disease P

2006
Free serum concentrations of the protein-bound retention solute p-cresol predict mortality in hemodialysis patients.
    Kidney international, 2006, Volume: 69, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Cohort Studies; Confidence Intervals; Creatinine; Cresols; Disease P

2006
Free serum concentrations of the protein-bound retention solute p-cresol predict mortality in hemodialysis patients.
    Kidney international, 2006, Volume: 69, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Cohort Studies; Confidence Intervals; Creatinine; Cresols; Disease P

2006
Free serum concentrations of the protein-bound retention solute p-cresol predict mortality in hemodialysis patients.
    Kidney international, 2006, Volume: 69, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Cohort Studies; Confidence Intervals; Creatinine; Cresols; Disease P

2006
Free serum concentrations of the protein-bound retention solute p-cresol predict mortality in hemodialysis patients.
    Kidney international, 2006, Volume: 69, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Cohort Studies; Confidence Intervals; Creatinine; Cresols; Disease P

2006
Kidney failure and the gut: p-cresol and the dangers from within.
    Kidney international, 2006, Volume: 69, Issue:6

    Topics: Colon; Cresols; Disease Progression; Humans; Kidney Failure, Chronic; Predictive Value of Tests; Ren

2006