4-cresol has been researched along with Obesity in 3 studies
4-cresol: RN given refers to parent cpd
p-cresol : A cresol that consists of toluene substituted by a hydroxy group at position 4. It is a metabolite of aromatic amino acid metabolism produced by intestinal microflora in humans and animals.
Obesity: A status with BODY WEIGHT that is grossly above the recommended standards, usually due to accumulation of excess FATS in the body. The standards may vary with age, sex, genetic or cultural background. In the BODY MASS INDEX, a BMI greater than 30.0 kg/m2 is considered obese, and a BMI greater than 40.0 kg/m2 is considered morbidly obese (MORBID OBESITY).
| Excerpt | Relevance | Reference |
|---|---|---|
| " The chronic administration of non-toxic doses of 4-cresol in complementary preclinical models of CMD reduces adiposity, glucose intolerance, and liver triglycerides, enhances insulin secretion in vivo, stimulates islet density and size, and pancreatic β-cell proliferation, and increases vascularization, suggesting activated islet enlargement." | 1.56 | The Natural Metabolite 4-Cresol Improves Glucose Homeostasis and Enhances β-Cell Function. ( Alzaid, F; Brial, F; Dumas, ME; Gauguier, D; Hedjazi, L; Kamatani, Y; Lathrop, M; Le Lay, A; Magnan, C; Matsuda, F; Meneyrol, K; Péan, N; Sato, TA; Sonomura, K; Venteclef, N; Zalloua, P, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 2 (66.67) | 2.80 |
| Authors | Studies |
|---|---|
| Jalaleddine, N | 1 |
| Hachim, M | 1 |
| Al-Hroub, H | 1 |
| Saheb Sharif-Askari, N | 1 |
| Senok, A | 1 |
| Elmoselhi, A | 1 |
| Mahboub, B | 1 |
| Samuel Kurien, NM | 1 |
| Kandasamy, RK | 1 |
| Semreen, MH | 1 |
| Halwani, R | 1 |
| Soares, NC | 1 |
| Al Heialy, S | 1 |
| Brial, F | 1 |
| Alzaid, F | 1 |
| Sonomura, K | 1 |
| Kamatani, Y | 1 |
| Meneyrol, K | 1 |
| Le Lay, A | 1 |
| Péan, N | 1 |
| Hedjazi, L | 1 |
| Sato, TA | 1 |
| Venteclef, N | 1 |
| Magnan, C | 1 |
| Lathrop, M | 1 |
| Dumas, ME | 1 |
| Matsuda, F | 1 |
| Zalloua, P | 1 |
| Gauguier, D | 1 |
| Brinkworth, GD | 1 |
| Noakes, M | 1 |
| Clifton, PM | 1 |
| Bird, AR | 1 |
1 trial available for 4-cresol and Obesity
| Article | Year |
|---|---|
Comparative effects of very low-carbohydrate, high-fat and high-carbohydrate, low-fat weight-loss diets on bowel habit and faecal short-chain fatty acids and bacterial populations.
Topics: Adult; Analysis of Variance; Colony Count, Microbial; Cresols; Defecation; Diet, Carbohydrate-Restri | 2009 |
2 other studies available for 4-cresol and Obesity
| Article | Year |
|---|---|
N6-Acetyl-L-Lysine and p-Cresol as Key Metabolites in the Pathogenesis of COVID-19 in Obese Patients.
Topics: COVID-19; Cresols; Humans; Lysine; Metabolomics; Obesity; SARS-CoV-2 | 2022 |
The Natural Metabolite 4-Cresol Improves Glucose Homeostasis and Enhances β-Cell Function.
Topics: Animals; B-Lymphocytes; Blood Glucose; Cell Proliferation; Cresols; Diabetes Mellitus, Type 2; Homeo | 2020 |