Page last updated: 2024-10-25

4-cresol and Innate Inflammatory Response

4-cresol has been researched along with Innate Inflammatory Response in 7 studies

4-cresol: RN given refers to parent cpd
p-cresol : A cresol that consists of toluene substituted by a hydroxy group at position 4. It is a metabolite of aromatic amino acid metabolism produced by intestinal microflora in humans and animals.

Research Excerpts

ExcerptRelevanceReference
"Compared with the control subjects, ESRD patients had significantly lower breath-test derived indexes of protein assimilation [%max=3."1.32Impairment of small intestinal protein assimilation in patients with end-stage renal disease: extending the malnutrition-inflammation-atherosclerosis concept. ( Bammens, B; Evenepoel, P; Vanrenterghem, Y; Verbeke, K, 2004)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19901 (14.29)18.7374
1990's0 (0.00)18.2507
2000's1 (14.29)29.6817
2010's3 (42.86)24.3611
2020's2 (28.57)2.80

Authors

AuthorsStudies
Di Paola, R1
De, A1
Izhar, R1
Abate, M1
Zappavigna, S1
Capasso, A1
Perna, AF1
La Russa, A1
Capasso, G1
Caraglia, M1
Simeoni, M1
Zayed, M1
Iohara, K1
Wong, J1
Piceno, YM1
DeSantis, TZ1
Pahl, M1
Andersen, GL1
Vaziri, ND1
Riccio, E1
Cataldi, M1
Minco, M1
Argentino, G1
Russo, R1
Brancaccio, S1
Memoli, A1
Grumetto, L1
Postiglione, L1
Guida, B1
Memoli, B1
Chang, MC1
Chang, HH1
Chan, CP1
Yeung, SY1
Hsien, HC1
Lin, BR1
Yeh, CY1
Tseng, WY1
Tseng, SK1
Jeng, JH1
BUSCH, K1
Bammens, B1
Evenepoel, P1
Verbeke, K1
Vanrenterghem, Y1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effects of Synbiotics Supplementation on the Concentration of the Uremic Toxin Indoxyl Sulfate, Symptoms of Constipation, and Constipation-related Quality of Life in End-stage Renal Disease Patients Undergoing Hemodialysis[NCT04527640]60 participants (Anticipated)Interventional2020-09-15Not yet recruiting
Prebiotic Therapy to Improve Outcomes of Renal Transplant[NCT04428190]Early Phase 160 participants (Anticipated)Interventional2022-02-23Recruiting
Role of HFR Cartridge in the Removal of Mediators of Inflammation and P-cresol in Hemodialysis Patients[NCT01865773]8 participants (Actual)Interventional2011-01-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for 4-cresol and Innate Inflammatory Response

ArticleYear
Possible Effects of Uremic Toxins p-Cresol, Indoxyl Sulfate, p-Cresyl Sulfate on the Development and Progression of Colon Cancer in Patients with Chronic Renal Failure.
    Genes, 2023, 06-13, Volume: 14, Issue:6

    Topics: Colonic Neoplasms; Humans; Indican; Inflammation; Kidney Failure, Chronic; Renal Insufficiency, Chro

2023

Other Studies

6 other studies available for 4-cresol and Innate Inflammatory Response

ArticleYear
Effects of
    International journal of molecular sciences, 2020, Sep-21, Volume: 21, Issue:18

    Topics: Animals; Cell Differentiation; Cell Survival; Cellular Senescence; Cresols; Dental Pulp; Dogs; Infla

2020
Expansion of urease- and uricase-containing, indole- and p-cresol-forming and contraction of short-chain fatty acid-producing intestinal microbiota in ESRD.
    American journal of nephrology, 2014, Volume: 39, Issue:3

    Topics: Adult; Aged; Ammonia; Cresols; Diet; Fatty Acids, Volatile; Female; Humans; Indican; Indoles; Inflam

2014
Expansion of urease- and uricase-containing, indole- and p-cresol-forming and contraction of short-chain fatty acid-producing intestinal microbiota in ESRD.
    American journal of nephrology, 2014, Volume: 39, Issue:3

    Topics: Adult; Aged; Ammonia; Cresols; Diet; Fatty Acids, Volatile; Female; Humans; Indican; Indoles; Inflam

2014
Expansion of urease- and uricase-containing, indole- and p-cresol-forming and contraction of short-chain fatty acid-producing intestinal microbiota in ESRD.
    American journal of nephrology, 2014, Volume: 39, Issue:3

    Topics: Adult; Aged; Ammonia; Cresols; Diet; Fatty Acids, Volatile; Female; Humans; Indican; Indoles; Inflam

2014
Expansion of urease- and uricase-containing, indole- and p-cresol-forming and contraction of short-chain fatty acid-producing intestinal microbiota in ESRD.
    American journal of nephrology, 2014, Volume: 39, Issue:3

    Topics: Adult; Aged; Ammonia; Cresols; Diet; Fatty Acids, Volatile; Female; Humans; Indican; Indoles; Inflam

2014
Evidence that p-cresol and IL-6 are adsorbed by the HFR cartridge: towards a new strategy to decrease systemic inflammation in dialyzed patients?
    PloS one, 2014, Volume: 9, Issue:4

    Topics: Adsorption; Aged; Cresols; Female; Hemodiafiltration; Hemodialysis Solutions; Humans; Inflammation;

2014
p-Cresol affects reactive oxygen species generation, cell cycle arrest, cytotoxicity and inflammation/atherosclerosis-related modulators production in endothelial cells and mononuclear cells.
    PloS one, 2014, Volume: 9, Issue:12

    Topics: Apoptosis; Atherosclerosis; Cell Cycle Checkpoints; Cell Proliferation; Cresols; Dinoprost; Endothel

2014
[The effects of metacresol sulfonic acid on defects and inflammations of the genital mucosa].
    Munchener medizinische Wochenschrift (1950), 1955, May-20, Volume: 97, Issue:20

    Topics: Cresols; Formaldehyde; Genital Diseases, Female; Humans; Inflammation; Mucous Membrane; Sulfonic Aci

1955
Impairment of small intestinal protein assimilation in patients with end-stage renal disease: extending the malnutrition-inflammation-atherosclerosis concept.
    The American journal of clinical nutrition, 2004, Volume: 80, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Arteriosclerosis; Breath Tests; Carbon Isotopes; Case-Control Studie

2004