Page last updated: 2024-10-25

4-cresol and Disease Exacerbation

4-cresol has been researched along with Disease Exacerbation in 6 studies

4-cresol: RN given refers to parent cpd
p-cresol : A cresol that consists of toluene substituted by a hydroxy group at position 4. It is a metabolite of aromatic amino acid metabolism produced by intestinal microflora in humans and animals.

Research Excerpts

ExcerptRelevanceReference
" after a cocktail of poorly absorbed antibiotics to suppress gut microbiota."1.91Atlas of gut microbe-derived products from aromatic amino acids and risk of cardiovascular morbidity and mortality. ( Bäckhed, F; Buffa, JA; Demuth, I; Fischbach, MA; Haghikia, A; Hazen, SL; König, M; Landmesser, U; Li, L; Li, XS; Nemet, I; Romano, KA; Steinhagen-Thiessen, E; Tang, WHW; Wilcox, J; Witkowski, M, 2023)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (33.33)29.6817
2010's3 (50.00)24.3611
2020's1 (16.67)2.80

Authors

AuthorsStudies
Nemet, I1
Li, XS1
Haghikia, A1
Li, L1
Wilcox, J1
Romano, KA1
Buffa, JA1
Witkowski, M1
Demuth, I1
König, M1
Steinhagen-Thiessen, E1
Bäckhed, F1
Fischbach, MA1
Tang, WHW1
Landmesser, U1
Hazen, SL1
Liu, Y1
Li, J1
Yu, J1
Wang, Y1
Lu, J1
Shang, EX1
Zhu, Z1
Guo, J1
Duan, J1
Guida, B1
Germanò, R1
Trio, R1
Russo, D1
Memoli, B1
Grumetto, L1
Barbato, F1
Cataldi, M1
Huang, ST1
Shu, KH1
Cheng, CH1
Wu, MJ1
Yu, TM1
Chuang, YW1
Chen, CH1
Bammens, B1
Evenepoel, P1
Keuleers, H1
Verbeke, K1
Vanrenterghem, Y1
Ketteler, M1

Clinical Trials (5)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Fecal Microbiota Transplantation as a Therapeutic Strategy in the Progression of Chronic Kidney Disease[NCT04361097]28 participants (Actual)Interventional2018-08-07Completed
EFFECT OF SHORT-TERM TREATMENT WITH THE SYNBIOTIC PROBINUL-NEUTRO® ON GASTROINTESTINAL SYMPTOMS AND CIRCULATING PLASMA p-CRESOL LEVEL IN PATIENTS WITH CHRONIC RENAL FAILURE: A RANDOMIZED DOUBLE BLIND PILOT STUDY.[NCT02008331]Phase 430 participants (Actual)Interventional2013-04-30Completed
Study on the Effect of Flucloxacillin on the Serum Level of P-cresol in Peritoneal Dialysis Patients[NCT00433342]Phase 19 participants (Actual)Interventional2006-03-31Terminated
A Multicentric Observational Trial on Protein Bound Uremic Toxins in Nocturnal Hemodialysis[NCT00417339]38 participants (Actual)Observational2006-12-31Completed
A Multicentric Observational Study on the Removal of Protein-Bound Uremic Retention Solutes in Nocturnal Hemodialysis: A Cross-Sectional Analysis[NCT00417105]120 participants (Actual)Observational2006-12-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for 4-cresol and Disease Exacerbation

ArticleYear
Effect of short-term synbiotic treatment on plasma p-cresol levels in patients with chronic renal failure: a randomized clinical trial.
    Nutrition, metabolism, and cardiovascular diseases : NMCD, 2014, Volume: 24, Issue:9

    Topics: Aged; Cresols; Disease Progression; Double-Blind Method; Female; Glomerular Filtration Rate; Humans;

2014
Effect of short-term synbiotic treatment on plasma p-cresol levels in patients with chronic renal failure: a randomized clinical trial.
    Nutrition, metabolism, and cardiovascular diseases : NMCD, 2014, Volume: 24, Issue:9

    Topics: Aged; Cresols; Disease Progression; Double-Blind Method; Female; Glomerular Filtration Rate; Humans;

2014
Effect of short-term synbiotic treatment on plasma p-cresol levels in patients with chronic renal failure: a randomized clinical trial.
    Nutrition, metabolism, and cardiovascular diseases : NMCD, 2014, Volume: 24, Issue:9

    Topics: Aged; Cresols; Disease Progression; Double-Blind Method; Female; Glomerular Filtration Rate; Humans;

2014
Effect of short-term synbiotic treatment on plasma p-cresol levels in patients with chronic renal failure: a randomized clinical trial.
    Nutrition, metabolism, and cardiovascular diseases : NMCD, 2014, Volume: 24, Issue:9

    Topics: Aged; Cresols; Disease Progression; Double-Blind Method; Female; Glomerular Filtration Rate; Humans;

2014

Other Studies

5 other studies available for 4-cresol and Disease Exacerbation

ArticleYear
Atlas of gut microbe-derived products from aromatic amino acids and risk of cardiovascular morbidity and mortality.
    European heart journal, 2023, 08-22, Volume: 44, Issue:32

    Topics: Amino Acids, Aromatic; Animals; Disease Progression; Gastrointestinal Microbiome; Glucuronides; Glut

2023
Disorder of gut amino acids metabolism during CKD progression is related with gut microbiota dysbiosis and metagenome change.
    Journal of pharmaceutical and biomedical analysis, 2018, Feb-05, Volume: 149

    Topics: Amino Acids; Animals; Bacteria; Bacterial Physiological Phenomena; Cresols; Disease Models, Animal;

2018
Serum total p-cresol and indoxyl sulfate correlated with stage of chronic kidney disease in renal transplant recipients.
    Transplantation proceedings, 2012, Volume: 44, Issue:3

    Topics: Adult; Cresols; Disease Progression; Female; Humans; Indican; Kidney Failure, Chronic; Kidney Transp

2012
Free serum concentrations of the protein-bound retention solute p-cresol predict mortality in hemodialysis patients.
    Kidney international, 2006, Volume: 69, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Cohort Studies; Confidence Intervals; Creatinine; Cresols; Disease P

2006
Free serum concentrations of the protein-bound retention solute p-cresol predict mortality in hemodialysis patients.
    Kidney international, 2006, Volume: 69, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Cohort Studies; Confidence Intervals; Creatinine; Cresols; Disease P

2006
Free serum concentrations of the protein-bound retention solute p-cresol predict mortality in hemodialysis patients.
    Kidney international, 2006, Volume: 69, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Cohort Studies; Confidence Intervals; Creatinine; Cresols; Disease P

2006
Free serum concentrations of the protein-bound retention solute p-cresol predict mortality in hemodialysis patients.
    Kidney international, 2006, Volume: 69, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Cohort Studies; Confidence Intervals; Creatinine; Cresols; Disease P

2006
Free serum concentrations of the protein-bound retention solute p-cresol predict mortality in hemodialysis patients.
    Kidney international, 2006, Volume: 69, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Cohort Studies; Confidence Intervals; Creatinine; Cresols; Disease P

2006
Free serum concentrations of the protein-bound retention solute p-cresol predict mortality in hemodialysis patients.
    Kidney international, 2006, Volume: 69, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Cohort Studies; Confidence Intervals; Creatinine; Cresols; Disease P

2006
Free serum concentrations of the protein-bound retention solute p-cresol predict mortality in hemodialysis patients.
    Kidney international, 2006, Volume: 69, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Cohort Studies; Confidence Intervals; Creatinine; Cresols; Disease P

2006
Free serum concentrations of the protein-bound retention solute p-cresol predict mortality in hemodialysis patients.
    Kidney international, 2006, Volume: 69, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Cohort Studies; Confidence Intervals; Creatinine; Cresols; Disease P

2006
Free serum concentrations of the protein-bound retention solute p-cresol predict mortality in hemodialysis patients.
    Kidney international, 2006, Volume: 69, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Cohort Studies; Confidence Intervals; Creatinine; Cresols; Disease P

2006
Kidney failure and the gut: p-cresol and the dangers from within.
    Kidney international, 2006, Volume: 69, Issue:6

    Topics: Colon; Cresols; Disease Progression; Humans; Kidney Failure, Chronic; Predictive Value of Tests; Ren

2006