4-cresol has been researched along with Diabetes Mellitus, Type 2 in 3 studies
4-cresol: RN given refers to parent cpd
p-cresol : A cresol that consists of toluene substituted by a hydroxy group at position 4. It is a metabolite of aromatic amino acid metabolism produced by intestinal microflora in humans and animals.
Diabetes Mellitus, Type 2: A subclass of DIABETES MELLITUS that is not INSULIN-responsive or dependent (NIDDM). It is characterized initially by INSULIN RESISTANCE and HYPERINSULINEMIA; and eventually by GLUCOSE INTOLERANCE; HYPERGLYCEMIA; and overt diabetes. Type II diabetes mellitus is no longer considered a disease exclusively found in adults. Patients seldom develop KETOSIS but often exhibit OBESITY.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Fifty-five patients with type II diabetes mellitus were divided into two groups: case and control." | 1.91 | Serum Levels of Indoxyl Sulfate and P-cresol in Type II Diabetic Patients With and Without Nephropathy. ( Aliasgharzadeh, A; Jouyban, A; Moradi, M; Oladi-Ghadikolaei, R; Shayanfar, A; Soleymani, J; Tayebi Khosroshahi, H, 2023) |
| " The chronic administration of non-toxic doses of 4-cresol in complementary preclinical models of CMD reduces adiposity, glucose intolerance, and liver triglycerides, enhances insulin secretion in vivo, stimulates islet density and size, and pancreatic β-cell proliferation, and increases vascularization, suggesting activated islet enlargement." | 1.56 | The Natural Metabolite 4-Cresol Improves Glucose Homeostasis and Enhances β-Cell Function. ( Alzaid, F; Brial, F; Dumas, ME; Gauguier, D; Hedjazi, L; Kamatani, Y; Lathrop, M; Le Lay, A; Magnan, C; Matsuda, F; Meneyrol, K; Péan, N; Sato, TA; Sonomura, K; Venteclef, N; Zalloua, P, 2020) |
| "The rat model of type II diabetes mellitus was constructed by an injection of streptozocin (40 mg/kg), along with diets of fat emulsion." | 1.38 | [Exploring the mechanism of rhizoma coptidis in treating type II diabetes mellitus based on metabolomics by gas chromatography-mass spectrometry]. ( Kong, H; Li, Y; Lu, X; Wang, J; Xu, G; Yuan, Z, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 2 (66.67) | 2.80 |
| Authors | Studies |
|---|---|
| Oladi-Ghadikolaei, R | 1 |
| Aliasgharzadeh, A | 1 |
| Shayanfar, A | 1 |
| Soleymani, J | 1 |
| Moradi, M | 1 |
| Jouyban, A | 1 |
| Tayebi Khosroshahi, H | 1 |
| Brial, F | 1 |
| Alzaid, F | 1 |
| Sonomura, K | 1 |
| Kamatani, Y | 1 |
| Meneyrol, K | 1 |
| Le Lay, A | 1 |
| Péan, N | 1 |
| Hedjazi, L | 1 |
| Sato, TA | 1 |
| Venteclef, N | 1 |
| Magnan, C | 1 |
| Lathrop, M | 1 |
| Dumas, ME | 1 |
| Matsuda, F | 1 |
| Zalloua, P | 1 |
| Gauguier, D | 1 |
| Wang, J | 1 |
| Yuan, Z | 1 |
| Kong, H | 1 |
| Li, Y | 1 |
| Lu, X | 1 |
| Xu, G | 1 |
3 other studies available for 4-cresol and Diabetes Mellitus, Type 2
| Article | Year |
|---|---|
Serum Levels of Indoxyl Sulfate and P-cresol in Type II Diabetic Patients With and Without Nephropathy.
Topics: Creatinine; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Humans; Indican; Proteinuria; Uric Ac | 2023 |
The Natural Metabolite 4-Cresol Improves Glucose Homeostasis and Enhances β-Cell Function.
Topics: Animals; B-Lymphocytes; Blood Glucose; Cell Proliferation; Cresols; Diabetes Mellitus, Type 2; Homeo | 2020 |
[Exploring the mechanism of rhizoma coptidis in treating type II diabetes mellitus based on metabolomics by gas chromatography-mass spectrometry].
Topics: Animals; Antioxidants; Benzoic Acid; Blood Glucose; Coptis chinensis; Cresols; Diabetes Complication | 2012 |