Page last updated: 2024-10-25

4-cresol and Cardiovascular Diseases

4-cresol has been researched along with Cardiovascular Diseases in 6 studies

4-cresol: RN given refers to parent cpd
p-cresol : A cresol that consists of toluene substituted by a hydroxy group at position 4. It is a metabolite of aromatic amino acid metabolism produced by intestinal microflora in humans and animals.

Cardiovascular Diseases: Pathological conditions involving the CARDIOVASCULAR SYSTEM including the HEART; the BLOOD VESSELS; or the PERICARDIUM.

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (50.00)29.6817
2010's3 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Poesen, R1
Viaene, L2
Verbeke, K3
Augustijns, P1
Bammens, B3
Claes, K2
Kuypers, D2
Evenepoel, P3
Meijers, B1
Winchester, JF1
Hostetter, TH1
Meyer, TW1
Meijers, BK2
de Loor, H1
Vanrenterghem, Y2
Neirynck, N1
Vanholder, R2
Schepers, E1
Eloot, S1
Pletinck, A1
Glorieux, G1
De Moor, B1
Lameire, N1
De Smet, R1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Single Centre Observational Cohort Study on the Prognostic Relevance of P-cresol and Related Uremic Retention Solutes in the Development and/or Progression of Renal Failure and Cardiovascular Disease in Chronic Kidney Disease Patients[NCT00441623]499 participants (Actual)Observational2005-10-31Completed
A Phase 1/2 Study on the Effects of BENEO synergy1 on the Generation Rate and Serum Concentration of P-cresol and Related Protein-fermentation Endproducts in Haemodialysis Patients[NCT00695513]Phase 1/Phase 222 participants (Anticipated)Interventional2006-03-31Completed
[NCT00888030]300 participants (Actual)Observational2006-05-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for 4-cresol and Cardiovascular Diseases

ArticleYear
An update on uremic toxins.
    International urology and nephrology, 2013, Volume: 45, Issue:1

    Topics: beta 2-Microglobulin; Biomarkers; Cardiovascular Diseases; Cresols; Dialysis Solutions; Fibroblast G

2013
Uremic toxins and peritoneal dialysis.
    Kidney international. Supplement, 2001, Volume: 78

    Topics: Animals; beta 2-Microglobulin; Cardiovascular Diseases; Cresols; Cytokines; Glycation End Products,

2001

Trials

1 trial available for 4-cresol and Cardiovascular Diseases

ArticleYear
Cardiovascular disease relates to intestinal uptake of p-cresol in patients with chronic kidney disease.
    BMC nephrology, 2014, Jun-09, Volume: 15

    Topics: Aged; Aged, 80 and over; Belgium; Biomarkers; Cardiovascular Diseases; Comorbidity; Cresols; Female;

2014

Other Studies

3 other studies available for 4-cresol and Cardiovascular Diseases

ArticleYear
p-Cresol sulfate: further understanding of its cardiovascular disease potential in CKD.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2009, Volume: 54, Issue:5

    Topics: Cardiovascular Diseases; Chronic Disease; Cresols; Humans; Kidney Diseases

2009
p-Cresol and cardiovascular risk in mild-to-moderate kidney disease.
    Clinical journal of the American Society of Nephrology : CJASN, 2010, Volume: 5, Issue:7

    Topics: Aged; Belgium; Biomarkers; Cardiovascular Diseases; Cresols; Female; Glomerular Filtration Rate; Hum

2010
Free p-cresol is associated with cardiovascular disease in hemodialysis patients.
    Kidney international, 2008, Volume: 73, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Cardiovascular Diseases; Cresols; Female; Humans; Male; Middle Aged;

2008
Free p-cresol is associated with cardiovascular disease in hemodialysis patients.
    Kidney international, 2008, Volume: 73, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Cardiovascular Diseases; Cresols; Female; Humans; Male; Middle Aged;

2008
Free p-cresol is associated with cardiovascular disease in hemodialysis patients.
    Kidney international, 2008, Volume: 73, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Cardiovascular Diseases; Cresols; Female; Humans; Male; Middle Aged;

2008
Free p-cresol is associated with cardiovascular disease in hemodialysis patients.
    Kidney international, 2008, Volume: 73, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Cardiovascular Diseases; Cresols; Female; Humans; Male; Middle Aged;

2008