4-cresol has been researched along with Bladder Cancer in 3 studies
4-cresol: RN given refers to parent cpd
p-cresol : A cresol that consists of toluene substituted by a hydroxy group at position 4. It is a metabolite of aromatic amino acid metabolism produced by intestinal microflora in humans and animals.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Their involvement in the development of human bladder cancer has been determined by measuring the urinary excretion of indican (indoxyl sulphate) and conjugated phenols." | 3.67 | Microbial amino acid metabolites and bladder cancer: no evidence of promoting activity in man. ( George, CF; Lawrie, CA; Renwick, AG; Thakrar, A, 1988) |
| "To understand the impact of PC on bladder cancer progression, human bladder cancer TSGH8301 cells were treated PC with various concentration (25-100 μM)." | 1.51 | The uremic toxin p-cresol promotes the invasion and migration on carcinoma cells via Ras and mTOR signaling. ( Chang, HR; Hsu, YH; Huang, HP, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Oto, J | 1 |
| Fernández-Pardo, Á | 1 |
| Roca, M | 1 |
| Plana, E | 1 |
| Cana, F | 1 |
| Herranz, R | 1 |
| Pérez-Ardavín, J | 1 |
| Vera-Donoso, CD | 1 |
| Martínez-Sarmiento, M | 1 |
| Medina, P | 1 |
| Hsu, YH | 1 |
| Huang, HP | 1 |
| Chang, HR | 1 |
| Renwick, AG | 1 |
| Thakrar, A | 1 |
| Lawrie, CA | 1 |
| George, CF | 1 |
1 review available for 4-cresol and Bladder Cancer
| Article | Year |
|---|---|
LC-MS metabolomics of urine reveals distinct profiles for non-muscle-invasive and muscle-invasive bladder cancer.
Topics: Biomarkers; Biomarkers, Tumor; Chromatography, Liquid; Cresols; Glucuronides; Humans; Spermine; Tand | 2022 |
2 other studies available for 4-cresol and Bladder Cancer
| Article | Year |
|---|---|
The uremic toxin p-cresol promotes the invasion and migration on carcinoma cells via Ras and mTOR signaling.
Topics: Amides; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cresols; Everolimus; Humans; NF-kappa B | 2019 |
Microbial amino acid metabolites and bladder cancer: no evidence of promoting activity in man.
Topics: Aged; Aged, 80 and over; Carcinogens; Carcinoma, Transitional Cell; Cocarcinogenesis; Cresols; Femal | 1988 |