4-chlorokynurenine has been researched along with Depressive Disorder, Treatment-Resistant in 1 studies
*Depressive Disorder, Treatment-Resistant: Failure to respond to two or more trials of antidepressant monotherapy or failure to respond to four or more trials of different antidepressant therapies. (Campbell's Psychiatric Dictionary, 9th ed.) [MeSH]
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Adeojo, LW; Evans, JW; Farmer, CA; George, JM; Gould, TD; Greenstein, D; Henter, ID; Kadriu, B; Machado-Vieira, R; Mannes, AJ; Oppenheimer, M; Park, LT; Smith, MA; Snodgrass, HR; Yuan, P; Zanos, P; Zarate, CA | 1 |
1 trial(s) available for 4-chlorokynurenine and Depressive Disorder, Treatment-Resistant
| Article | Year |
|---|---|
A Randomized Trial of the N-Methyl-d-Aspartate Receptor Glycine Site Antagonist Prodrug 4-Chlorokynurenine in Treatment-Resistant Depression.
Topics: Adolescent; Adult; Aged; Animals; Antidepressive Agents; Brain; Brain Chemistry; Cross-Over Studies; Depressive Disorder, Treatment-Resistant; Double-Blind Method; Female; Glycine; Humans; Kynurenine; Magnetic Resonance Imaging; Male; Mice; Middle Aged; Prodrugs; Psychiatric Status Rating Scales; Receptors, N-Methyl-D-Aspartate; Treatment Outcome; Young Adult | 2020 |