4-carboxy-3-hydroxyphenylglycine has been researched along with Catatonic Rigidity in 2 studies
4-carboxy-3-hydroxyphenylglycine: weak agonist at metabotropic glutamate receptors; occludes the action of 1-aminocyclopentyl-1,3-dicarboxylate in hippocampus
| Excerpt | Relevance | Reference |
|---|---|---|
| "The aim of the present study was to determine whether S-4-carboxy-3-hydroxyphenylglycine (S)-4C3HPG, a mixed group I glutamate metabotropic receptor antagonist and a group II agonist, attenuated parkinsonian-like muscle rigidity in rats." | 3.71 | (S)-4C3HPG, a mixed group I mGlu receptor antagonist and a group II agonist, administered intrastriatally, counteracts parkinsonian-like muscle rigidity in rats. ( Lorenc-Koci, E; Pilc, A; Wardas, J; Wolfarth, S, 2001) |
| "In the search for a therapy of Parkinson's disease, ionotropic, mainly NMDA, receptor antagonists were found to have moderately beneficial, yet also some undesirable side-effects." | 1.31 | The role of metabotropic glutamate receptor (mGluR) ligands in parkinsonian muscle rigidity. ( Konieczny, J; Lorenc-Koci, E; Ossowska, K; Pilc, A; Wolfarth, S, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wolfarth, S | 2 |
| Konieczny, J | 1 |
| Lorenc-Koci, E | 2 |
| Ossowska, K | 1 |
| Pilc, A | 2 |
| Wardas, J | 1 |
2 other studies available for 4-carboxy-3-hydroxyphenylglycine and Catatonic Rigidity
| Article | Year |
|---|---|
The role of metabotropic glutamate receptor (mGluR) ligands in parkinsonian muscle rigidity.
Topics: Animals; Bridged Bicyclo Compounds; Electromyography; Glycine; Ligands; Male; Muscle Rigidity; Parki | 2000 |
(S)-4C3HPG, a mixed group I mGlu receptor antagonist and a group II agonist, administered intrastriatally, counteracts parkinsonian-like muscle rigidity in rats.
Topics: Animals; Anti-Dyskinesia Agents; Corpus Striatum; Disease Models, Animal; Electromyography; Glycine; | 2001 |