Page last updated: 2024-08-18

4-butyrolactone and Pregnancy

4-butyrolactone has been researched along with Pregnancy in 25 studies

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-19907 (28.00)18.7374
1990's0 (0.00)18.2507
2000's7 (28.00)29.6817
2010's10 (40.00)24.3611
2020's1 (4.00)2.80

Authors

AuthorsStudies
Benson, SM; Berghaus, LJ; Berghaus, RD; Burden, CA; Giguère, S; Hart, KA; Hayna, JT; Horohov, DW; Kelleman, AA; Lyle, SK; Macpherson, ML; Mallicote, MF; Pozor, MA; Randell, SA; Varner, JC1
Alvarenga, MA; Andrade, VP; Fernandes, CB; Freitas-Dell'Aqua, CP; Nichi, M; Okada, CTC; Papa, FO1
Coetzee, JF; Cooper, VL; Jaberi-Douraki, M; Kleinhenz, K; Kleinhenz, MD; Lechtenberg, K; Mazloom, R; Schieber, T; Seagen, J; Sidhu, PK; Wulf, LW1
Alvarenga, MA; Correal, SB; Cyrino, M; Dell'Aqua, JA; Freitas-Dell'Aqua, CP; Friso, AM; Miró, J; Papa, FO; Segabinazzi, LGTM; Teoro do Carmo, M1
Barr, DB; Louis, GM; Maisog, JM; Mumford, SL; Parker, DL; Pfeiffer, CM; Rybak, ME; Schisterman, EF; Sundaram, R; Sweeney, AM1
Benson, SM; Cox, S; Giguère, S; Macpherson, ML; McNaughten, JW; Pozor, MA1
Boyd Barr, D; Buck Louis, GM; Chen, Z; Kim, S; Mumford, SL1
Zachut, M1
Abarzua, S; Chrobak, M; Jeschke, U; Kuhn, C; Piechulla, B; Richter, DU; Schröder, L; Schulze, S; Weissenbacher, T1
Aronsen, L; Fuskevåg, OM; Raknes, G1
Adona, PR; Bressan, FF; Chiaratti, MR; De Bem, TH; Fantinato-Neto, P; Leal, CL; Meirelles, FV; Miranda, MS; Perecin, F; Pimentel, JR; Pires, PR; Rochetti, R; Sampaio, RV; Sangalli, JR; Schwartz, KR; Smith, LC1
Chamorro, G; Madrigal, E; Salazar, M; Vega, F1
Chamorro, G; Madrigal, E; Mercado, E; Salazar, M; Vega, F1
Engel, SM; Kaplan, D; Levy, B; Liu, Z; Wolff, MS1
Chen, CJ; Chen, ST; Chien, CM; Hsieh, JF; Tsai, CC; Wu, TH1
Adona, PR; Leal, CL; Pires, PR; Quetglas, MD; Schwarz, KR1
Aja, S; Aplasca, A; Daniels, K; Hyun, J; Kemm, M; Kleman, AM; Kuhajda, FP; Landree, LE; McFadden, JM; Medghalchi, SM; Moran, TH; Plummer, E; Ronnett, GV; Thupari, JN; Townsend, CA; Vadlamudi, A1
Adlercreatz, H; Anderson, LC; Axelson, M; Borriello, SP; Gordon, H; Harkness, R; Kirk, DN; Lawson, AM; Morgan, DM; Setchell, KD1
Axelson, M; Setchell, KD1
Axelson, M; Conway, E; Cooley, G; Farrant, RD; Kirk, DN; Lawson, AM; Setchell, KD; Taylor, NF; Wynn, S1
Funke, CW; Groen, MB; Leemhuis, J; Stitch, SR; Toumba, JK; Vink, J; Woods, GF1
Adlercreut, H; Hallmans, G; Hultén, K; Kilkkinen, A; Mazur, W; Pietinen, P; Stumpf, K1
Beattie, CW; Corbin, A; Gluckman, MI1
Ali, SF; Gough, BJ; Holson, RR; Newport, GD; Scalzo, FM1
Arvidsson, S; Holmberg, B; Kronevi, T1

Reviews

1 review(s) available for 4-butyrolactone and Pregnancy

ArticleYear
Food containing phytoestrogens, and breast cancer.
    BioFactors (Oxford, England), 2000, Volume: 12, Issue:1-4

    Topics: 4-Butyrolactone; Animals; Breast Neoplasms; Edible Grain; Estrogens; Estrogens, Non-Steroidal; Female; Finland; Food; Humans; Isoflavones; Japan; Lignans; Phytoestrogens; Plant Preparations; Pregnancy; Prenatal Exposure Delayed Effects

2000

Trials

4 trial(s) available for 4-butyrolactone and Pregnancy

ArticleYear
The effect of flunixin meglumine, firocoxib and meloxicam on the uterine mobility of equine embryos.
    Theriogenology, 2019, Jan-01, Volume: 123

    Topics: 4-Butyrolactone; Animals; Anti-Inflammatory Agents, Non-Steroidal; Clonixin; Embryo, Mammalian; Female; Horses; Meloxicam; Pregnancy; Prostaglandins; Sulfones; Ultrasonography, Prenatal

2019
Transmammary delivery of firocoxib to piglets reduces stress and improves average daily gain after castration, tail docking, and teeth clipping1.
    Journal of animal science, 2019, Jul-02, Volume: 97, Issue:7

    Topics: 4-Butyrolactone; Animal Welfare; Animals; Anti-Inflammatory Agents, Non-Steroidal; Female; Hydrocortisone; Injections, Intramuscular; Lactation; Male; Orchiectomy; Pain; Pregnancy; Random Allocation; Sulfones; Swine; Tooth; Weaning

2019
Periovulatory administration of firocoxib did not alter ovulation rates and mitigated post-breeding inflammatory response in mares.
    Theriogenology, 2019, Oct-15, Volume: 138

    Topics: 4-Butyrolactone; Animals; Anti-Inflammatory Agents, Non-Steroidal; Breeding; Cross-Over Studies; Drug Administration Schedule; Endometritis; Estrous Cycle; Female; Horse Diseases; Horses; Inflammation; Insemination, Artificial; Male; Ovulation; Pregnancy; Pregnancy Rate; Sulfones; Treatment Outcome

2019
Disposition of firocoxib in late pregnant and early postpartum mares.
    Journal of veterinary pharmacology and therapeutics, 2016, Volume: 39, Issue:2

    Topics: 4-Butyrolactone; Animals; Area Under Curve; Cyclooxygenase 2 Inhibitors; Female; Horses; Postpartum Period; Pregnancy; Pregnancy, Animal; Sulfones; Tissue Distribution

2016

Other Studies

20 other study(ies) available for 4-butyrolactone and Pregnancy

ArticleYear
Evidence for anti-inflammatory effects of firocoxib administered to mares with experimentally induced placentitis.
    American journal of reproductive immunology (New York, N.Y. : 1989), 2021, Volume: 86, Issue:1

    Topics: 4-Butyrolactone; Animals; Anti-Inflammatory Agents; Cyclooxygenase 2 Inhibitors; Female; Horse Diseases; Horses; Inflammation; Interleukin-6; Matrix Metalloproteinase 1; Placenta; Placenta Diseases; Pregnancy; Prostaglandins; Sulfones; Tumor Necrosis Factor-alpha

2021
Higher urinary lignan concentrations in women but not men are positively associated with shorter time to pregnancy.
    The Journal of nutrition, 2014, Volume: 144, Issue:3

    Topics: 4-Butyrolactone; Adolescent; Adult; Body Mass Index; Diet; Female; Humans; Isoflavones; Lignans; Male; Phytoestrogens; Pregnancy; Prospective Studies; Socioeconomic Factors; Time-to-Pregnancy; Young Adult

2014
Urinary Phytoestrogens Are Associated with Subtle Indicators of Semen Quality among Male Partners of Couples Desiring Pregnancy.
    The Journal of nutrition, 2015, Volume: 145, Issue:11

    Topics: 4-Butyrolactone; Adult; Body Mass Index; Cholesterol; Cotinine; DNA Fragmentation; Endpoint Determination; Female; Fertility; Genistein; Humans; Isoflavones; Lignans; Linear Models; Male; Phytoestrogens; Pregnancy; Prospective Studies; Semen Analysis

2015
Short communication: Concentrations of the mammalian lignan enterolactone in preovulatory follicles and the correlation with intrafollicular estradiol in dairy cows fed extruded flaxseed.
    Journal of dairy science, 2015, Volume: 98, Issue:12

    Topics: 4-Butyrolactone; Animals; Cattle; Diet; Dietary Supplements; Estradiol; Female; Flax; Follicular Fluid; Follicular Phase; Lactation; Lignans; Milk; Ovarian Follicle; Pregnancy; Progesterone

2015
Effects of Phytoestrogen Extracts Isolated from Elder Flower on Hormone Production and Receptor Expression of Trophoblast Tumor Cells JEG-3 and BeWo, as well as MCF7 Breast Cancer Cells.
    Nutrients, 2016, Oct-08, Volume: 8, Issue:10

    Topics: 4-Butyrolactone; Cell Line, Tumor; Cell Proliferation; Enzyme-Linked Immunosorbent Assay; Estradiol; Female; Humans; Immunohistochemistry; Lignans; MCF-7 Cells; Phytoestrogens; Plant Extracts; Pregnancy; Progesterone; Receptors, Estrogen; Sambucus; Trophoblastic Neoplasms; Uterine Neoplasms

2016
Urinary concentrations of gamma-hydroxybutyric acid and related compounds in pregnancy.
    Journal of analytical toxicology, 2010, Volume: 34, Issue:7

    Topics: 3-Hydroxybutyric Acid; 4-Butyrolactone; Chromatography, Liquid; Cross-Sectional Studies; False Positive Reactions; Female; Forensic Toxicology; Humans; Hydroxybutyrates; Pregnancy; Reference Values; Reproducibility of Results; Tandem Mass Spectrometry

2010
Viable calves produced by somatic cell nuclear transfer using meiotic-blocked oocytes.
    Cellular reprogramming, 2011, Volume: 13, Issue:5

    Topics: 4-Butyrolactone; Animals; Blastocyst; Brain-Derived Neurotrophic Factor; Cattle; Cloning, Organism; Female; Gene Expression Regulation, Developmental; Interferon Type I; Meiosis; Nuclear Transfer Techniques; Octamer Transcription Factor-3; Oocytes; Pregnancy; Pregnancy Proteins; Protein Kinase Inhibitors

2011
Reproductive toxicity of gamma-ethyl-gamma-phenyl-butyrolactone, a new anticonvulsant and hypnotic drug, in mice. Fertility and peri- and post-natal studies.
    Arzneimittel-Forschung, 2002, Volume: 52, Issue:7

    Topics: 4-Butyrolactone; Animals; Anticonvulsants; Birth Weight; Female; Fertility; Hypnotics and Sedatives; Male; Mice; No-Observed-Adverse-Effect Level; Pregnancy; Teratogens; Weight Gain

2002
Germ cell mutagenicity of gamma-ethyl-gamma-phenyl-butyrolactone (EPBL) detected in the CF1 mouse-dominant lethal study.
    Toxicology letters, 2003, Apr-30, Volume: 142, Issue:1-2

    Topics: 4-Butyrolactone; Animals; Corpus Luteum; Embryo Implantation; Embryo Loss; Epididymis; Female; Germ Cells; Male; Mice; Mutagens; Organ Size; Pregnancy; Random Allocation; Sperm Count; Sperm Motility; Spermatozoa; Testis

2003
Xenobiotic phenols in early pregnancy amniotic fluid.
    Reproductive toxicology (Elmsford, N.Y.), 2006, Volume: 21, Issue:1

    Topics: 4-Butyrolactone; Amniotic Fluid; Benzhydryl Compounds; Estrogens, Non-Steroidal; Female; Genistein; Humans; Isoflavones; Lignans; Maternal Exposure; Maternal-Fetal Exchange; Phenols; Phytoestrogens; Pregnancy; Xenobiotics

2006
A screening platform for compounds with potential immuno-regulatory activities using human cord blood mononuclear cells.
    Combinatorial chemistry & high throughput screening, 2006, Volume: 9, Issue:10

    Topics: 4-Butyrolactone; Antigens, CD; Antigens, Surface; Biological Factors; Cell Proliferation; Cells, Cultured; Combinatorial Chemistry Techniques; Drug Design; Female; Fetal Blood; Flow Cytometry; Humans; Immunophenotyping; Leukocytes, Mononuclear; Molecular Structure; Pregnancy

2006
Nuclear maturation kinetics and in vitro embryo development of cattle oocytes prematured with butyrolactone I combined or not combined with roscovitine.
    Animal reproduction science, 2008, Mar-03, Volume: 104, Issue:2-4

    Topics: 4-Butyrolactone; Animals; Cattle; Cell Culture Techniques; Culture Media; Embryonic Development; Female; Fertilization in Vitro; Male; Oocytes; Pregnancy; Protein Kinase Inhibitors; Purines; Roscovitine

2008
Pharmacological stimulation of brain carnitine palmitoyl-transferase-1 decreases food intake and body weight.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2008, Volume: 294, Issue:2

    Topics: 4-Butyrolactone; Animals; Body Weight; Carnitine O-Palmitoyltransferase; Cell Line, Tumor; Dose-Response Relationship, Drug; Eating; Energy Metabolism; Enzyme Activation; Enzyme Inhibitors; Epoxy Compounds; Fatty Acid Synthesis Inhibitors; Fatty Acids; Female; Hypothalamus; Injections, Intraventricular; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Neurons; Pregnancy; Rats

2008
Lignan formation in man--microbial involvement and possible roles in relation to cancer.
    Lancet (London, England), 1981, Jul-04, Volume: 2, Issue:8236

    Topics: 4-Butyrolactone; Bacteria; Butylene Glycols; Clostridium; Depression, Chemical; Female; Humans; Intestines; Lignans; Male; Menstruation; Metronidazole; Neoplasms; Oxytetracycline; Plant Extracts; Pregnancy

1981
Conjugation of lignans in human urine.
    FEBS letters, 1980, Dec-15, Volume: 122, Issue:1

    Topics: 4-Butyrolactone; Adult; Age Factors; Butylene Glycols; Chromatography, Gas; Female; Furans; Glucuronates; Humans; Lignans; Male; Mass Spectrometry; Middle Aged; Plant Extracts; Pregnancy; Sex Factors

1980
The definitive identification of the lignans trans-2,3-bis(3-hydroxybenzyl)-gamma-butyrolactone and 2,3-bis(3-hydroxybenzyl)butane-1,4-diol in human and animal urine.
    The Biochemical journal, 1981, Aug-01, Volume: 197, Issue:2

    Topics: 4-Butyrolactone; Animals; Butylene Glycols; Chemical Phenomena; Chemistry; Chlorocebus aethiops; Chromatography, Gas; Chromatography, Thin Layer; Female; Furans; Gas Chromatography-Mass Spectrometry; Humans; Lignans; Magnetic Resonance Spectroscopy; Mass Spectrometry; Pregnancy

1981
Excretion, isolation and structure of a new phenolic constituent of female urine.
    Nature, 1980, Oct-23, Volume: 287, Issue:5784

    Topics: 4-Butyrolactone; Adult; Cresols; Female; Humans; Lignans; Magnetic Resonance Spectroscopy; Mass Spectrometry; Menstruation; Ovulation; Pregnancy; Spectrophotometry, Infrared

1980
A comparison of gamma-butyrolactone and pimozide on serum gonadotrophins and ovulation in the rat.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1976, Volume: 153, Issue:1

    Topics: 4-Butyrolactone; Animals; Female; Follicle Stimulating Hormone; Furans; Luteinizing Hormone; Ovulation; Pimozide; Pregnancy; Proestrus; Rats; Receptors, Dopamine

1976
Chronic prenatal haloperidol exposure: lack of effect on presynaptic dopamine autoreceptors.
    Neurotoxicology, 1989,Fall, Volume: 10, Issue:3

    Topics: 4-Butyrolactone; Animals; Apomorphine; Brain Chemistry; Caudate Nucleus; Chromatography, High Pressure Liquid; Dihydroxyphenylalanine; Female; Haloperidol; Hydrazines; Nucleus Accumbens; Olfactory Bulb; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Inbred Strains; Receptors, Dopamine; Synapses

1989
Teratogenicity test of gamma-butyrolactone in the Sprague-Dawley rat.
    Pharmacology & toxicology, 1988, Volume: 62, Issue:1

    Topics: 4-Butyrolactone; Abnormalities, Drug-Induced; Animals; Body Weight; Female; Furans; Growth; Pregnancy; Rats; Rats, Inbred Strains

1988