Page last updated: 2024-08-18

4-butyrolactone and Obesity

4-butyrolactone has been researched along with Obesity in 25 studies

Research

Studies (25)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	17 (68.00)	29.6817
2010's	7 (28.00)	24.3611
2020's	1 (4.00)	2.80

Authors

Authors	Studies
Guo, S; Wang, G; Yang, Z	1
Tsujino, Y	1
Andreoli, R; Archetti, I; Biasiotto, G; Cadei, M; De Palma, G; Di Lorenzo, D; Luzzani, M; Monti, E; Mozzoni, P; Pacchetti, B; Predolini, F; Serana, F; Smeds, A; Zanella, I	1
Frankenfeld, CL	2
Gu, A; Jiang, ZY; Liu, Q; Xu, C; Zhang, Q	1
Fu, Q; Hu, Y; Lv, Q; Qiu, J; Tan, Q; Tang, S; Yang, J; Zhang, J; Zhou, Y	1
Adlercreutz, H; Borgquist, S; Ericson, U; Gullberg, B; Landberg, G; Olsson, H; Sonestedt, E; Wirfält, E	1
Adlercreutz, H; Håkansson, N; Lagergren, J; Lin, Y; Lu, Y; Peñalvo, JL; Wolk, A	1
Adlercreutz, H; Jacobs, DR; Pereira, MA; Pins, JJ; Stumpf, K	1
Borisy-Rudin, FF; Brown, P; Kim, EK; Kuhajda, FP; Landree, LE; Miller, I; Moran, TH; Ronnett, GV; Tihan, T; Townsend, CA; Witters, LA	1
Kim, EK; Kuhajda, FP; Moran, TH; Ronnett, GV; Thupari, JN	1
Cha, SH; Hu, Z; Lane, MD	1
Kim, EK; Kuhajda, FP; Moran, TH; Pinn, ML; Ronnett, GV; Thupari, JN; Tu, Y	1
Adlercreutz, H; Biessy, C; Bylund, A; Hallmans, G; Kaaks, R; Stattin, P	1
Kim, EK; Landree, LE; Ronnett, GV; Tu, Y	1
Kuhajda, FP; Landree, LE; Ronnett, GV	1
Kim, EK; Kleman, AM; Landree, LE; Ronnett, GV; Tu, Y	1
Du, XM; Furusho, N; Hayashi, J; Irino, N; Shoyama, Y	1
Bouchard, C	1
Kumar, MV; Lane, MD; Nagy, TR; Shimokawa, T	1
Senior, K	1
Makimura, H; Mobbs, CV	1
Kuhajda, FP; Landree, LE; Ronnett, GV; Thupari, JN	1
Hirsch, J	1

Reviews

5 review(s) available for 4-butyrolactone and Obesity

Article	Year
Gastrointestinal microbiome and breast cancer: correlations, mechanisms and potential clinical implications. Breast cancer (Tokyo, Japan), 2017, Volume: 24, Issue:2 Topics: 4-Butyrolactone; Animals; Breast Neoplasms; Diet; Estrogens; Female; Gastrointestinal Microbiome; Humans; Lignans; Obesity	2017
Fatty acid metabolism as a target for obesity treatment. Physiology & behavior, 2005, May-19, Volume: 85, Issue:1 Topics: 4-Butyrolactone; Animals; Body Weight; Carnitine O-Palmitoyltransferase; Cerulenin; Eating; Energy Metabolism; Fatty Acid Synthases; Fatty Acids; Gene Expression; Humans; Models, Biological; Obesity	2005
Fatty acid metabolism, the central nervous system, and feeding. Obesity (Silver Spring, Md.), 2006, Volume: 14 Suppl 5 Topics: 4-Butyrolactone; Central Nervous System; Eating; Energy Intake; Energy Metabolism; Fatty Acid Synthases; Fatty Acids; Gene Expression; Humans; Obesity; Oxidation-Reduction; Weight Loss	2006
Pharmacologically active compounds in the Anoectochilus and Goodyera species. Journal of natural medicines, 2008, Volume: 62, Issue:2 Topics: 4-Butyrolactone; Adipose Tissue; Animals; Carbon Tetrachloride Poisoning; Glycosides; Hepatocytes; Humans; Hyperlipidemias; Hypolipidemic Agents; Lipid Metabolism; Liver; Monosaccharides; Obesity; Orchidaceae; Phytotherapy; Plant Extracts; Plant Preparations; Protective Agents; Stereoisomerism	2008
Inhibition of food intake by inhibitors of fatty acid synthase. The New England journal of medicine, 2000, Dec-21, Volume: 343, Issue:25 Topics: 4-Butyrolactone; Acetyl-CoA Carboxylase; Animals; Eating; Enzyme Inhibitors; Fatty Acid Synthases; Humans; Mice; Neuropeptide Y; Obesity; Triglycerides; Weight Loss	2000

Trials

1 trial(s) available for 4-butyrolactone and Obesity

Article	Year
Whole grain food intake elevates serum enterolactone. The British journal of nutrition, 2002, Volume: 88, Issue:2 Topics: 4-Butyrolactone; Adult; Avena; Cross-Over Studies; Diet; Dietary Fiber; Female; Humans; Lignans; Male; Middle Aged; Obesity; Oryza; Regression Analysis; Sex Distribution; Triticum	2002

Other Studies

19 other study(ies) available for 4-butyrolactone and Obesity

Article	Year
Ligustilide alleviates the insulin resistance, lipid accumulation, and pathological injury with elevated phosphorylated AMPK level in rats with diabetes mellitus. Journal of receptor and signal transduction research, 2021, Volume: 41, Issue:1 Topics: 4-Butyrolactone; AMP-Activated Protein Kinase Kinases; Animals; Blood Glucose; Diabetes Mellitus; Diabetes Mellitus, Experimental; Diet, High-Fat; Humans; Insulin; Insulin Resistance; Lipid Metabolism; Liver; NF-E2-Related Factor 2; Obesity; Phosphorylation; Protein Kinases; Rats	2021
A New Agonist for Peroxisome Proliferation-activated Receptor γ (PPARγ), Fraglide-1 from Zhenjiang Fragrant Vinegar: Screening and Characterization Based on Cell Culture Experiments. Journal of oleo science, 2017, Jun-01, Volume: 66, Issue:6 Topics: 4-Butyrolactone; Acetic Acid; Animals; Anti-Obesity Agents; Cells, Cultured; Chlorocebus aethiops; Chromans; Diabetes Mellitus; Dietary Supplements; Dose-Response Relationship, Drug; Insulin Resistance; Obesity; Oryza; Phytotherapy; PPAR gamma; Thiazolidinediones; Troglitazone; Uncoupling Protein 1	2017
7-Hydroxymatairesinol improves body weight, fat and sugar metabolism in C57BJ/6 mice on a high-fat diet. The British journal of nutrition, 2018, Volume: 120, Issue:7 Topics: 3T3-L1 Cells; 4-Butyrolactone; Adipogenesis; Adipose Tissue; Animals; Anti-Obesity Agents; Blood Glucose; Body Weight; Diet, High-Fat; Dietary Supplements; Fatty Liver; Gene Expression; Insulin Resistance; Lignans; Lipid Metabolism; Lipids; Male; Metabolic Syndrome; Mice; Mice, Inbred C57BL; Obesity; Picea; Plant Extracts	2018
Relationship of obesity and high urinary enterolignan concentrations in 6806 children and adults: analysis of National Health and Nutrition Examination Survey data. European journal of clinical nutrition, 2013, Volume: 67, Issue:8 Topics: 4-Butyrolactone; Adolescent; Adult; Bacteria; Biomarkers; Child; Female; Gastrointestinal Tract; Humans; Lignans; Logistic Models; Male; Microbiota; Obesity; Overweight; Risk Factors; Waist Circumference	2013
Cardiometabolic risk factors are associated with high urinary enterolactone concentration, independent of urinary enterodiol concentration and dietary fiber intake in adults. The Journal of nutrition, 2014, Volume: 144, Issue:9 Topics: 4-Butyrolactone; Adult; Aged; Aged, 80 and over; Blood Glucose; Blood Pressure; C-Reactive Protein; Cardiovascular Diseases; Cholesterol, HDL; Dietary Fiber; Female; Humans; Lignans; Logistic Models; Male; Metabolic Syndrome; Middle Aged; Nutrition Surveys; Obesity; Odds Ratio; Phytoestrogens; Risk Factors; Triglycerides	2014
Urinary enterolactone is associated with obesity and metabolic alteration in men in the US National Health and Nutrition Examination Survey 2001-10. The British journal of nutrition, 2015, Feb-28, Volume: 113, Issue:4 Topics: 4-Butyrolactone; Adolescent; Adult; Age Factors; Aged; Body Mass Index; Child; Cross-Sectional Studies; Down-Regulation; Female; Humans; Lignans; Logistic Models; Male; Metabolic Syndrome; Middle Aged; Nutrition Surveys; Obesity; Phytoestrogens; Sex Characteristics; United States; Waist Circumference; Young Adult	2015
Enterolactone is differently associated with estrogen receptor beta-negative and -positive breast cancer in a Swedish nested case-control study. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2008, Volume: 17, Issue:11 Topics: 4-Butyrolactone; Adult; Aged; Biomarkers, Tumor; Breast Neoplasms; Case-Control Studies; Diet; Estrogen Receptor alpha; Estrogen Receptor beta; Female; Humans; Lignans; Linear Models; Microarray Analysis; Middle Aged; Obesity; Prospective Studies; Reproducibility of Results; Risk Assessment; Smoking; Surveys and Questionnaires; Sweden	2008
Validation of FFQ-based assessment of dietary lignans compared with serum enterolactone in Swedish women. The British journal of nutrition, 2013, May-28, Volume: 109, Issue:10 Topics: 4-Butyrolactone; Aged; Biomarkers; Diet; Female; Humans; Lignans; Middle Aged; Obesity; Phytoestrogens; Reproducibility of Results; Surveys and Questionnaires; Sweden	2013
Expression of FAS within hypothalamic neurons: a model for decreased food intake after C75 treatment. American journal of physiology. Endocrinology and metabolism, 2002, Volume: 283, Issue:5 Topics: 4-Butyrolactone; Acetyl-CoA Carboxylase; Adult; Aged; Amino Acid Sequence; Animals; Appetite; Arcuate Nucleus of Hypothalamus; Carboxy-Lyases; Conditioning, Psychological; Eating; Enzyme Inhibitors; Fasting; Fatty Acid Synthases; Female; Gene Expression Regulation, Enzymologic; Humans; Immunohistochemistry; Liver; Male; Mice; Mice, Inbred BALB C; Middle Aged; Molecular Sequence Data; Neurons; Neuropeptide Y; Obesity; Paraventricular Hypothalamic Nucleus; RNA, Messenger; Taste	2002
Chronic C75 treatment of diet-induced obese mice increases fat oxidation and reduces food intake to reduce adipose mass. American journal of physiology. Endocrinology and metabolism, 2004, Volume: 287, Issue:1 Topics: 4-Butyrolactone; Adipose Tissue; Animals; Body Weight; Carnitine O-Palmitoyltransferase; Chronic Disease; Diet; Eating; Fatty Acid Synthases; Fatty Acids; Fatty Liver; Male; Mice; Mice, Inbred C57BL; Obesity; Oxidation-Reduction; Treatment Outcome	2004
Long-term effects of a fatty acid synthase inhibitor on obese mice: food intake, hypothalamic neuropeptides, and UCP3. Biochemical and biophysical research communications, 2004, Apr-30, Volume: 317, Issue:2 Topics: 4-Butyrolactone; Adaptation, Physiological; Animals; Blood Glucose; Body Weight; Carrier Proteins; Dose-Response Relationship, Drug; Drinking; Drug Tolerance; Eating; Fatty Acid Synthases; Homeostasis; Hypothalamus; Ion Channels; Male; Mice; Mice, Inbred C57BL; Mitochondrial Proteins; Muscle, Skeletal; Neuropeptides; Obesity; Reference Values; Treatment Outcome; Uncoupling Protein 3	2004
C75 alters central and peripheral gene expression to reduce food intake and increase energy expenditure. Endocrinology, 2005, Volume: 146, Issue:1 Topics: 4-Butyrolactone; Animals; Body Weight; Diet; Eating; Energy Metabolism; Fatty Acid Synthases; Fatty Acids; Gene Expression; Hypothalamus; Male; Mice; Mice, Inbred C57BL; Neuropeptides; Obesity; Oxidation-Reduction; Thinness	2005
Prospective study of plasma enterolactone and prostate cancer risk (Sweden). Cancer causes & control : CCC, 2004, Volume: 15, Issue:10 Topics: 4-Butyrolactone; Cohort Studies; Humans; Life Style; Lignans; Male; Middle Aged; Obesity; Phytoestrogens; Prospective Studies; Prostatic Neoplasms; Risk; Smoking; Sweden	2004
The connections between C75 and obesity drug-target pathways. Trends in pharmacological sciences, 2005, Volume: 26, Issue:11 Topics: 4-Butyrolactone; AMP-Activated Protein Kinases; Animals; Anorexia; Carnitine O-Palmitoyltransferase; Disease Models, Animal; Eating; Energy Metabolism; Enzyme Inhibitors; Fatty Acid Synthases; Fatty Acids; Feeding Behavior; Hypothalamus; Mice; Multienzyme Complexes; Obesity; Protein Serine-Threonine Kinases; Rats; Rhombencephalon	2005
Differential effects of a centrally acting fatty acid synthase inhibitor in lean and obese mice. Proceedings of the National Academy of Sciences of the United States of America, 2002, Feb-19, Volume: 99, Issue:4 Topics: 4-Butyrolactone; Animals; Body Weight; Down-Regulation; Enzyme Inhibitors; Fatty Acid Synthases; Hypothalamus; Mice; Mice, Inbred C57BL; Mice, Obese; Obesity; Ribonucleases; RNA, Messenger; Time Factors; Up-Regulation	2002
Thin mice and fat mice respond differently to appetite suppressant. Lancet (London, England), 2002, Feb-23, Volume: 359, Issue:9307 Topics: 4-Butyrolactone; Animals; Disease Models, Animal; Fatty Acid Synthases; Mice; Obesity	2002
Block the FAS, lose the fat. Nature medicine, 2002, Volume: 8, Issue:4 Topics: 4-Butyrolactone; Animals; Anti-Obesity Agents; Cerulenin; Enzyme Inhibitors; Fatty Acid Synthases; Humans; Hypothalamus; Mice; Mice, Obese; Models, Biological; Obesity	2002
C75 increases peripheral energy utilization and fatty acid oxidation in diet-induced obesity. Proceedings of the National Academy of Sciences of the United States of America, 2002, Jul-09, Volume: 99, Issue:14 Topics: 3T3 Cells; 4-Butyrolactone; Adenosine Triphosphate; Adipocytes; Animals; Carnitine O-Palmitoyltransferase; Diet; Energy Metabolism; Enzyme Inhibitors; Epoxy Compounds; Fatty Acid Synthases; Fatty Acids; Humans; Male; Malonyl Coenzyme A; Mice; Mice, Inbred C57BL; Obesity; Oxidation-Reduction; Tumor Cells, Cultured; Weight Loss	2002
The search for new ways to treat obesity. Proceedings of the National Academy of Sciences of the United States of America, 2002, Jul-09, Volume: 99, Issue:14 Topics: 4-Butyrolactone; Adipose Tissue; Animals; Carnitine O-Palmitoyltransferase; Cell Size; Cerulenin; Energy Intake; Fatty Acids; Ghrelin; Humans; Malonyl Coenzyme A; Obesity; Peptide Hormones; Peptides	2002