4-butyrolactone has been researched along with Lung Neoplasms in 17 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (5.88) | 18.7374 |
| 1990's | 3 (17.65) | 18.2507 |
| 2000's | 5 (29.41) | 29.6817 |
| 2010's | 6 (35.29) | 24.3611 |
| 2020's | 2 (11.76) | 2.80 |
| Authors | Studies |
|---|---|
| An, H; Bai, X; Guo, S; Kang, X; Li, S; Liu, X; Shi, S | 1 |
| Bai, J; Ding, X; Jiang, X; Qian, M; Wu, H; Zhang, X; Zhao, W; Zhu, F | 1 |
| Bidoli, P; Cho, BC; Chouaid, C; Corral Jaime, J; Dennis, PA; Garassino, MC; Gray, JE; Huang, Y; Kim, JH; Lena, H; Mazières, J; Park, K; Powderly, J; Rizvi, NA; Soo, RA; Vansteenkiste, J; Wadsworth, C; Wheatley-Price, P | 1 |
| Lambert, IH; Thorsteinsdottir, M; Thorsteinsdottir, UA | 1 |
| Burlison, JA; Li, C; Lu, H; Machen, TE; Neely, AM; Schwarzer, C; Stivers, NS; White, C; Whitt, AG; Zhao, G | 1 |
| Borowicz, P; Chikara, S; Christofidou-Solomidou, M; Lindsey, K; Reindl, KM | 1 |
| Chen, CJ; Chen, YL; Harn, HJ; Lin, CJ; Lin, SZ; Su, KJ; Wei, CW; Yiang, GT; Yu, YL | 1 |
| Blancafort, A; Cufí, S; Haro, D; Marrero, PF; Oliveras, G; Puig, T; Relat, J | 1 |
| Alvey, S; Gabrielson, E; Gabrielson, K; Hagemann, RL; Kuhajda, FP; Lee, JS; Orita, H; Pomper, MG | 1 |
| Chen, CY; Chen, YY; Hsu, YL; Huang, MS; Hung, JY; Kuo, PL | 1 |
| Chang, WL; Chen, SP; Chen, YL; Cheng, YL; Harn, HJ; Lin, CC; Lin, PC; Lin, SZ; Tsai, NM | 1 |
| Fang, XP; Gu, ZM; McLaughlin, JL; Rieser, MJ; Wood, KV; Zeng, L | 1 |
| Gu, Z; Hopp, DC; McLaughlin, JL; Zeng, L | 1 |
| Kawabata, K; Matsunaga, K; Mori, H; Nishikawa, A; Sugie, S; Tanakamaru, Y; Yamada, Y | 1 |
| Aoyagi, K; Basaki, Y; Chikahisa, L; Hashimoto, A; Miyadera, K; Okabe, S; Yamada, Y; Yonekura, K | 1 |
| Chang, J; Xu, YM; Xuan, LJ; Zhang, JS | 1 |
| Apiou, F; Boyland, E; Castegarno, M; Rudali, G | 1 |
1 trial(s) available for 4-butyrolactone and Lung Neoplasms
| Article | Year |
|---|---|
Durvalumab as third-line or later treatment for advanced non-small-cell lung cancer (ATLANTIC): an open-label, single-arm, phase 2 study.
Topics: 4-Butyrolactone; Aged; Anaplastic Lymphoma Kinase; Antibodies, Monoclonal; Antineoplastic Agents, Immunological; Aspartate Aminotransferases; B7-H1 Antigen; Carcinoma, Non-Small-Cell Lung; Diarrhea; ErbB Receptors; Fatigue; Female; gamma-Glutamyltransferase; Humans; Injection Site Reaction; Lung Neoplasms; Male; Middle Aged; Mutation; Pneumonia; Progression-Free Survival; Response Evaluation Criteria in Solid Tumors | 2018 |
16 other study(ies) available for 4-butyrolactone and Lung Neoplasms
| Article | Year |
|---|---|
Multi-target tracheloside and doxorubicin combined treatment of lung adenocarcinoma.
Topics: 4-Butyrolactone; Adenocarcinoma of Lung; Apoptosis; Cell Line, Tumor; Doxorubicin; Glucosides; Humans; Lung Neoplasms; Molecular Docking Simulation | 2022 |
Ligustilide inhibits the proliferation of non-small cell lung cancer via glycolytic metabolism.
Topics: 4-Butyrolactone; A549 Cells; Animals; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Glycolysis; Humans; Lung Neoplasms; Mice; Mice, Inbred BALB C; Mice, Nude; Random Allocation | 2021 |
Protolichesterinic Acid, Isolated from the Lichen Cetraria islandica, Reduces LRRC8A Expression and Volume-Sensitive Release of Organic Osmolytes in Human Lung Epithelial Cancer Cells.
Topics: 4-Butyrolactone; Apoptosis; Arachidonate 5-Lipoxygenase; bcl-2-Associated X Protein; Cell Cycle; Cell Line, Tumor; Cell Survival; Cisplatin; Cyclin-Dependent Kinase Inhibitor p21; Humans; Hydroxyeicosatetraenoic Acids; Lichens; Lung Neoplasms; Membrane Proteins; Parmeliaceae; Taurine | 2016 |
N-(3-oxo-acyl) homoserine lactone inhibits tumor growth independent of Bcl-2 proteins.
Topics: 4-Butyrolactone; Animals; Apoptosis; Aryldialkylphosphatase; Carcinoma, Lewis Lung; Carcinoma, Non-Small-Cell Lung; Cell Proliferation; Female; Flow Cytometry; Fluorescent Antibody Technique; Homoserine; Humans; Immunoenzyme Techniques; Lung Neoplasms; Mice; Mice, Inbred C57BL; Mice, Nude; Mitochondria; Proto-Oncogene Proteins c-bcl-2; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2016 |
Enterolactone alters FAK-Src signaling and suppresses migration and invasion of lung cancer cell lines.
Topics: 4-Butyrolactone; Cell Adhesion; Cell Line, Tumor; Cell Movement; Cytoskeleton; Flax; Focal Adhesion Kinase 1; Humans; Lignans; Lung Neoplasms; Phosphorylation; Plant Extracts; Signal Transduction; src-Family Kinases | 2017 |
Synergistic anti-tumor activity of isochaihulactone and paclitaxel on human lung cancer cells.
Topics: 4-Butyrolactone; Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Benzodioxoles; Blotting, Western; Cell Line, Tumor; Cell Proliferation; Drug Synergism; Growth Differentiation Factor 15; Humans; Immunohistochemistry; Lung Neoplasms; MAP Kinase Signaling System; Paclitaxel | 2012 |
Different fatty acid metabolism effects of (-)-epigallocatechin-3-gallate and C75 in adenocarcinoma lung cancer.
Topics: 4-Butyrolactone; Adenocarcinoma; Adenocarcinoma of Lung; Analysis of Variance; Animals; Apoptosis; Carnitine O-Palmitoyltransferase; Catechin; Cell Line, Tumor; Fatty Acid Synthases; Fatty Acids; Female; Humans; Lung Neoplasms; Mice; Mice, Inbred BALB C; Mice, Nude; Phosphorylation; Random Allocation; Signal Transduction; Weight Loss; Xenograft Model Antitumor Assays | 2012 |
FDG-PET for pharmacodynamic assessment of the fatty acid synthase inhibitor C75 in an experimental model of lung cancer.
Topics: 4-Butyrolactone; Animals; Disease Models, Animal; Enzyme Inhibitors; Fatty Acid Synthases; Fluorodeoxyglucose F18; Lung Neoplasms; Positron-Emission Tomography; Rats | 2007 |
Isokotomolide A, a new butanolide extracted from the leaves of Cinnamomum kotoense, arrests cell cycle progression and induces apoptosis through the induction of p53/p21 and the initiation of mitochondrial system in human non-small cell lung cancer A549 c
Topics: 4-Butyrolactone; Antineoplastic Agents, Phytogenic; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cyclin-Dependent Kinase Inhibitor p21; Humans; Lung Neoplasms; Mitochondria; Tumor Suppressor Protein p53 | 2007 |
Activation of nonsteroidal anti-inflammatory drug-activated gene-1 via extracellular signal-regulated kinase 1/2 mitogen-activated protein kinase revealed a isochaihulactone-triggered apoptotic pathway in human lung cancer A549 cells.
Topics: 4-Butyrolactone; Antineoplastic Agents; Apoptosis; Benzodioxoles; Cell Line, Tumor; Cytokines; Early Growth Response Protein 1; Gene Expression Regulation; Growth Differentiation Factor 15; Humans; Lung Neoplasms; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Oligonucleotide Array Sequence Analysis; Phosphatidylinositol 3-Kinases; Promoter Regions, Genetic | 2007 |
Five novel mono-tetrahydrofuran ring acetogenins from the seeds of Annona muricata.
Topics: 4-Butyrolactone; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Drug Screening Assays, Antitumor; HT29 Cells; Humans; Lung Neoplasms; Plant Tumors; Plants, Medicinal; Seeds; Tumor Cells, Cultured | 1996 |
Squamotacin: an annonaceous acetogenin with cytotoxic selectivity for the human prostate tumor cell line (PC-3).
Topics: 4-Butyrolactone; Animals; Antineoplastic Agents, Phytogenic; Artemia; Breast Neoplasms; Colonic Neoplasms; Humans; Kidney Neoplasms; Lung Neoplasms; Male; Pancreatic Neoplasms; Plants, Medicinal; Prostatic Neoplasms; Tumor Cells, Cultured | 1996 |
Effects of protocatechuic acid, S-methylmethanethiosulfonate or 5-hydroxy-4-(2-phenyl-(E)ethenyl)-2(5H)-furanone(KYN-54) on 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced pulmonary carcinogenesis in mice.
Topics: 4-Butyrolactone; Adenoma; Animals; Anticarcinogenic Agents; Carcinogens; Drug Screening Assays, Antitumor; Female; Hydroxybenzoates; Lung Neoplasms; Methyl Methanesulfonate; Mice; Mice, Inbred A; Nitrosamines; Retinoids | 1999 |
[Anti-angiogenic activities of UFT and its metabolites, GHB and GBL, in the dorsal air sac (DAS) model in mice].
Topics: 4-Butyrolactone; Animals; Antineoplastic Combined Chemotherapy Protocols; Female; Humans; Kidney Neoplasms; Lung Neoplasms; Mice; Mice, Inbred BALB C; Neovascularization, Pathologic; Sodium Oxybate; Stomach Neoplasms; Tegafur; Tumor Cells, Cultured; Uracil | 2000 |
Cytotoxic terpenoid and immunosuppressive phenolic glycosides from the root bark of Dictamnus dasycarpus.
Topics: 4-Butyrolactone; Carbon Isotopes; Disaccharides; Furans; Glucosides; Glycosides; Humans; Immunosuppressive Agents; Lung Neoplasms; Magnetic Resonance Spectroscopy; Molecular Structure; Plant Bark; Plant Roots; Rutaceae; Terpenes; Tumor Cells, Cultured | 2002 |
[The cancerogenic activity of gamma-butyrolactone in mice].
Topics: 4-Butyrolactone; Animals; Female; Furans; Lung Neoplasms; Male; Mammary Neoplasms, Experimental; Mice; Neoplasms, Experimental | 1976 |