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4-butyrolactone and Epilepsy, Absence

4-butyrolactone has been researched along with Epilepsy, Absence in 20 studies

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19901 (5.00)18.7374
1990's7 (35.00)18.2507
2000's6 (30.00)29.6817
2010's6 (30.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Arcaro, JA; Leung, LS; Mirsattari, SM; Mousavi, SR; Tenney, JR1
Chen, CC; Cheong, E; Choi, EJ; Latchoumane, C; Lee, B; Lee, CJ; Lee, J; Lee, SE; Oh, SJ; Park, C; Saud, ZA; Shin, HS; Sun, N1
Bonifácio, MJ; Pires, NM; Soares-da-Silva, P1
Arcaro, J; Chu, L; Kuo, M; Ma, J; Mirsattari, SM; Stan Leung, L1
Ahmed, M; Burnham, WM; Chan, KF; Chieverton, L; Liu, RR; Scott, BW; Wong, G; Wood, J1
Cheong, E; Choi, JH; Lee, CJ; Lee, K; Park, C; Paydar, A; Shin, HS; Zaman, T1
Kato, S; Koriyama, Y; Liu, Z; Matsukawa, T; Takizawa, N; Tanaka, M1
Ferris, CF; King, JA; Marshall, PC; Tenney, JR1
Kang, UB; Kim, D; Kim, J; Lee, C; Ryu, MJ; Shin, HS; Yu, MH1
Dominguez, LG; Huo, JZ; Leshchenko, Y; Snead, OC; Velazquez, JL1
Covey, DF; Ferrendelli, JA; Klunk, WE; McKeon, A1
Snead, OC2
Baba, H; Ono, K; Sugai, S1
Aizawa, M; Fukuda, H; Ito, Y1
Fukuda, H; Ishige, K; Ito, Y1
Banerjee, PK; Brailowsky, S; Olsen, RW; Snead, OC; Tillakaratne, NJ; Tobin, AJ1
Banerjee, PK; Hu, RQ; Snead, OC1
Jeong, MJ; Keum, S; Kim, D; Kim, SS; Lee, T; McEnery, MW; Shin, HS; Song, I1
Bernasconi, R; Bittiger, H; Lauber, J; Leonhardt, T; Marescaux, C; Martin, P; Reymann, N; Rubio, V; Vergnes, M1

Other Studies

20 other study(ies) available for 4-butyrolactone and Epilepsy, Absence

ArticleYear
Functional connectivity of the hippocampus to the thalamocortical circuitry in an animal model of absence seizures.
    Epilepsy research, 2017, Volume: 137

    Topics: 4-Butyrolactone; Animals; Cerebral Cortex; Cerebrovascular Circulation; Disease Models, Animal; Epilepsy, Absence; Functional Laterality; Hippocampus; Male; Neural Pathways; Oxygen; Rats, Sprague-Dawley; Rest; Thalamus; Time Factors

2017
Rebound burst firing in the reticular thalamus is not essential for pharmacological absence seizures in mice.
    Proceedings of the National Academy of Sciences of the United States of America, 2014, Aug-12, Volume: 111, Issue:32

    Topics: 4-Butyrolactone; Action Potentials; Animals; Calcium Channels, T-Type; Disease Models, Animal; Electrophysiological Phenomena; Epilepsy, Absence; Mice; Mice, 129 Strain; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Patch-Clamp Techniques; Thalamic Nuclei

2014
Carbamazepine aggravates absence seizures in two dedicated mouse models.
    Pharmacological reports : PR, 2015, Volume: 67, Issue:5

    Topics: 4-Butyrolactone; Animals; Anticonvulsants; Calcium Channels, T-Type; Carbamazepine; Dose-Response Relationship, Drug; Electroencephalography; Epilepsy, Absence; Ethosuximide; Male; Mice; Mice, Inbred Strains; Motor Activity; Patch-Clamp Techniques; Psychomotor Performance; Receptors, GABA-A

2015
The hippocampus participates in a pharmacological rat model of absence seizures.
    Epilepsy research, 2016, Volume: 120

    Topics: 4-Butyrolactone; Animals; Cerebral Cortex; Cortical Synchronization; Disease Models, Animal; Electrodes, Implanted; Epilepsy, Absence; GABA-A Receptor Agonists; Hippocampus; Male; Muscimol; Neural Pathways; Neurons; Rats, Long-Evans; Receptors, GABA-A; Seizures; Thalamus; Theta Rhythm

2016
Cytogenesis in the adult rat dentate gyrus is increased following kindled seizures but is unaltered in pharmacological models of absence seizures.
    Epilepsy & behavior : E&B, 2010, Volume: 18, Issue:3

    Topics: 4-Butyrolactone; Animals; Animals, Newborn; Anticholesteremic Agents; Bromodeoxyuridine; Cell Count; Dentate Gyrus; Disease Models, Animal; Electroencephalography; Epilepsy, Absence; Gene Expression Regulation; Kindling, Neurologic; Male; Nerve Tissue Proteins; Neurogenesis; Rats; Rats, Long-Evans; trans-1,4-Bis(2-chlorobenzaminomethyl)cyclohexane Dihydrochloride

2010
Cav2.3 channels are critical for oscillatory burst discharges in the reticular thalamus and absence epilepsy.
    Neuron, 2011, Apr-14, Volume: 70, Issue:1

    Topics: 4-Butyrolactone; Action Potentials; Animals; Calcium Channels, R-Type; Cation Transport Proteins; Electroencephalography; Epilepsy, Absence; Mice; Mice, 129 Strain; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Reticular Formation; Thalamic Nuclei

2011
A dissociation of gamma-butyrolactone-induced absence seizure and CRE- and AP-1 DNA-binding activities in the developing rat brain.
    Neuroscience research, 2003, Volume: 45, Issue:4

    Topics: 4-Butyrolactone; Age Factors; Animals; Binding, Competitive; Brain; Cyclic AMP Response Element-Binding Protein; Electroencephalography; Epilepsy, Absence; Male; Rats; Rats, Sprague-Dawley; Transcription Factor AP-1

2003
fMRI of generalized absence status epilepticus in conscious marmoset monkeys reveals corticothalamic activation.
    Epilepsia, 2004, Volume: 45, Issue:10

    Topics: 4-Butyrolactone; Animals; Brain; Callithrix; Cerebral Cortex; Consciousness; Disease Models, Animal; Epilepsy, Absence; Magnetic Resonance Imaging; Male; Neural Pathways; Oxygen; Status Epilepticus; Thalamus

2004
Proteomic analysis of gamma-butyrolactone-treated mouse thalamus reveals dysregulated proteins upon absence seizure.
    Journal of neurochemistry, 2007, Volume: 102, Issue:3

    Topics: 4-Butyrolactone; Animals; Calcium-Binding Proteins; Convulsants; Cytoskeletal Proteins; Down-Regulation; Electrophoresis, Gel, Two-Dimensional; Epilepsy, Absence; Male; Mice; Nerve Tissue Proteins; Neurons; Neurotransmitter Agents; Presynaptic Terminals; Proteomics; Thalamus; Time Factors

2007
Typical versus atypical absence seizures: network mechanisms of the spread of paroxysms.
    Epilepsia, 2007, Volume: 48, Issue:8

    Topics: 4-Butyrolactone; Action Potentials; Animals; Cerebral Cortex; Cortical Spreading Depression; Cortical Synchronization; Disease Models, Animal; Electrodes, Implanted; Electroencephalography; Epilepsy, Absence; Hippocampus; Models, Neurological; Neural Inhibition; Neural Pathways; Rats; Rats, Long-Evans; Recruitment, Neurophysiological; Synaptic Transmission; Thalamus; trans-1,4-Bis(2-chlorobenzaminomethyl)cyclohexane Dihydrochloride

2007
Alpha-substituted gamma-butyrolactones: new class of anticonvulsant drugs.
    Science (New York, N.Y.), 1982, Sep-10, Volume: 217, Issue:4564

    Topics: 4-Butyrolactone; Animals; Anticonvulsants; Chemical Phenomena; Chemistry; Convulsants; Drug Evaluation, Preclinical; Electroencephalography; Epilepsy, Absence; Ethosuximide; Furans; Guinea Pigs; Mice; Structure-Activity Relationship; Trimethadione

1982
The ontogeny of [3H]gamma-hydroxybutyrate and [3H]GABAB binding sites: relation to the development of experimental absence seizures.
    Brain research, 1994, Oct-03, Volume: 659, Issue:1-2

    Topics: 4-Butyrolactone; Animals; Animals, Newborn; Binding Sites; Electrophysiology; Epilepsy, Absence; gamma-Aminobutyric Acid; Rats; Rats, Sprague-Dawley; Sodium Oxybate; Tritium

1994
A new chronic model of spontaneous nonconvulsive generalized seizures.
    The Japanese journal of psychiatry and neurology, 1993, Volume: 47, Issue:2

    Topics: 4-Butyrolactone; Animals; Cerebral Cortex; Corpus Callosum; Electroencephalography; Epilepsy, Absence; Epilepsy, Generalized; Ethosuximide; Evoked Potentials; Injections, Intraperitoneal; Male; Phenytoin; Rats; Rats, Wistar; Seizures; Sodium Oxybate; Valproic Acid

1993
Roles of gamma-aminobutyric acidB (GABA B) and gamma-hydroxybutyric acid receptors in hippocampal long-term potentiation and pathogenesis of absence seizures.
    Biological & pharmaceutical bulletin, 1997, Volume: 20, Issue:10

    Topics: 4-Butyrolactone; Animals; Anticonvulsants; Baclofen; Benzocycloheptenes; Electroencephalography; Epilepsy, Absence; Female; GABA Agonists; GABA Modulators; Hippocampus; Long-Term Potentiation; Male; Mice; Receptors, Cell Surface; Receptors, GABA-B

1997
Pharmacological profiles of absence seizure-induced increases in CRE- and AP-1 DNA-binding activities in gamma-butyrolactone-treated mice.
    Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology, 1998, Volume: 18, Issue:4

    Topics: 4-Butyrolactone; Activating Transcription Factor 2; Animals; Anticonvulsants; Brain; Brain Chemistry; Cerebral Cortex; Cyclic AMP Response Element-Binding Protein; Disease Models, Animal; DNA-Binding Proteins; Epilepsy, Absence; Ethosuximide; GABA Antagonists; Mice; Organophosphorus Compounds; Phosphinic Acids; Thalamus; Transcription Factor AP-1; Transcription Factors

1998
Alterations in GABAA receptor alpha 1 and alpha 4 subunit mRNA levels in thalamic relay nuclei following absence-like seizures in rats.
    Experimental neurology, 1998, Volume: 154, Issue:1

    Topics: 4-Butyrolactone; Animals; Epilepsy, Absence; GABA Antagonists; GABA Modulators; Gene Expression; Hippocampus; In Situ Hybridization; Male; Organophosphorus Compounds; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; RNA, Messenger; Thalamus; Time Factors

1998
Regulation of gamma-aminobutyric acid (GABA) release in cerebral cortex in the gamma-hydroxybutyric acid (GHB) model of absence seizures in rat.
    Neuropharmacology, 2000, Jan-28, Volume: 39, Issue:3

    Topics: 4-Butyrolactone; Animals; Cerebral Cortex; Electroencephalography; Epilepsy, Absence; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Hydroxybutyrates; Male; Microdialysis; Potassium Chloride; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; Solvents; Thalamus

2000
Lack of the burst firing of thalamocortical relay neurons and resistance to absence seizures in mice lacking alpha(1G) T-type Ca(2+) channels.
    Neuron, 2001, Jul-19, Volume: 31, Issue:1

    Topics: 4-Butyrolactone; Animals; Baclofen; Calcium Channels, T-Type; Cerebral Cortex; Electroencephalography; Epilepsy, Absence; Immunity, Innate; Membrane Potentials; Mice; Mice, Inbred C57BL; Mice, Knockout; Neurons; Protein Subunits; Receptors, GABA-B; Seizures; Thalamic Nuclei; Thalamus

2001
Evidence for G protein modulation of experimental-generalized absence seizures in rat.
    Neuroscience letters, 1992, Dec-14, Volume: 148, Issue:1-2

    Topics: 4-Butyrolactone; Animals; Cerebral Ventricles; Electroencephalography; Epilepsy, Absence; GTP-Binding Proteins; Injections, Intraventricular; Male; Pentylenetetrazole; Pertussis Toxin; Rats; Rats, Sprague-Dawley; Time Factors; Virulence Factors, Bordetella

1992
Experimental absence seizures: potential role of gamma-hydroxybutyric acid and GABAB receptors.
    Journal of neural transmission. Supplementum, 1992, Volume: 35

    Topics: 4-Butyrolactone; Animals; Baclofen; Brain; Cyclic GMP; Disease Models, Animal; Epilepsy, Absence; GABA-A Receptor Antagonists; Male; Organophosphorus Compounds; Rats; Rats, Inbred Strains; Receptors, GABA-A; Reference Values; Reproducibility of Results; Sodium Oxybate; Valproic Acid

1992