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4-butyrolactone and Drug Withdrawal Symptoms

4-butyrolactone has been researched along with Drug Withdrawal Symptoms in 31 studies

Research

Studies (31)

TimeframeStudies, this research(%)All Research%
pre-19901 (3.23)18.7374
1990's1 (3.23)18.2507
2000's12 (38.71)29.6817
2010's14 (45.16)24.3611
2020's3 (9.68)2.80

Authors

AuthorsStudies
Lu, HQ; Wang, WJ1
Brett, J; Ezard, N; Freeman, G; Lindsey, R; Roberts, DM; Rodgers, C; Siefried, KJ1
Bargel, S; Bonnet, A; Boukerma, AK; Chevallier, C; Dufayet, L; Evrard, M; Guillotin, S; Loeuillet, E; Paradis, C; Pouget, AM; Reynoard, J; Vaucel, JA1
Delic, M1
Choudhuri, D; Cross, S; Dargan, PI; Ranjith, G; Wood, DM1
Amore, M; Belvederi Murri, M; Cervetti, A; Ghio, L; Respino, M1
Bosch, OG; Seifritz, E1
Beurmanjer, H; Dijkstra, BA; Kamal, RM; Schellekens, A; van Noorden, MS; Wannet, W1
Hohl-Radke, F; Staedt, J; Voss, M1
Busch, HJ; Schwab, T; Supady, A1
Duketis, E; Holtmann, M; Maier, J; Poustka, F; Radeloff, D; Wagner, A; Wöckel, L; Zepf, FD1
Duketis, E; Holtmann, M; Maier, J; Poustka, F; Radeloff, D; Schirman, S; Wagner, A; Wöckel, L; Zepf, FD1
Kravos, M1
Bell, J; Collins, R1
Bhattacharya, IS; Bruce, M; Watson, F1
Blayac, JP; Boulenger, JP; Capdevielle, D; Deddouche, C; Eiden, C; Peyrière, H1
Kashyap, GL; Patel, AG1
Chwaluk, P; Rejmak, G1
Bramness, JG; Haugland, S1
Batalla, A; González, J; Ilzarbe, D; Soler, V1
Knudsen, K; Mégarbane, B; Schep, LJ; Slaughter, RJ; Vale, JA1
Palmer, RB1
Nelson, LS; Tarabar, AF1
Gibson, KM; Snead, OC1
Brown, PR; Froestl, W; Gibson, KM; Goodwin, AK; Griffiths, RR; Jakobs, C; Weerts, EM1
Carai, MA; Colombo, G; Gessa, GL; Lobina, C; Maccioni, P; Maher, TJ; Orru, A; Quang, LS1
Wax, PM; Wojtowicz, JM; Yarema, MC1
Castagna, F; Ferrara, SD; Frison, G; Gallimberti, L; Gessa, GL; Giorgetti, R; Palatini, P; Tedeschi, L1
Clark, RF; Ly, BT; Schneir, AB1
Aaron, CK; Burns, MJ; Greenberg, MJ; Sivilotti, ML1
Engel, J; Liljequist, S1

Reviews

12 review(s) available for 4-butyrolactone and Drug Withdrawal Symptoms

ArticleYear
Gamma-hydroxybutyrate (GHB), 1,4-butanediol (1,4BD), and gamma-butyrolactone (GBL) intoxication: A state-of-the-art review.
    Regulatory toxicology and pharmacology : RTP, 2023, Volume: 142

    Topics: 4-Butyrolactone; gamma-Aminobutyric Acid; Humans; Sodium Oxybate; Substance Withdrawal Syndrome

2023
Management and treatment of gamma butyrolactone withdrawal syndrome: a case report and review.
    Journal of psychiatric practice, 2014, Volume: 20, Issue:4

    Topics: 4-Butyrolactone; Adult; Barbiturates; Humans; Male; Phenobarbital; Solvents; Substance Withdrawal Syndrome; Treatment Outcome

2014
The behavioural profile of gamma-hydroxybutyrate, gamma-butyrolactone and 1,4-butanediol in humans.
    Brain research bulletin, 2016, Volume: 126, Issue:Pt 1

    Topics: 4-Butyrolactone; Animals; Butylene Glycols; Central Nervous System Depressants; Circadian Rhythm; Eating; Humans; Sexual Behavior; Social Behavior; Sodium Oxybate; Substance Withdrawal Syndrome

2016
Pharmacological Treatment in γ-Hydroxybutyrate (GHB) and γ-Butyrolactone (GBL) Dependence: Detoxification and Relapse Prevention.
    CNS drugs, 2017, Volume: 31, Issue:1

    Topics: 4-Butyrolactone; Animals; Humans; Inactivation, Metabolic; Secondary Prevention; Sodium Oxybate; Substance Withdrawal Syndrome; Substance-Related Disorders

2017
[Withdrawal syndrome after abuse of GHB (Gamma-Hydroxybutyrate) and its physiological precursors - its relevance for child and adolescent psychiatrists].
    Zeitschrift fur Kinder- und Jugendpsychiatrie und Psychotherapie, 2009, Volume: 37, Issue:5

    Topics: 4-Butyrolactone; Acute Disease; Adolescent; Anesthetics, Intravenous; Antipsychotic Agents; Benzodiazepines; Butylene Glycols; Child; Critical Care; Delusions; Diagnosis, Differential; Drug Interactions; Humans; Psychoses, Substance-Induced; Sodium Oxybate; Substance Withdrawal Syndrome; Substance-Related Disorders

2009
[Abuse of γ-hydroxybutyrate].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 2011, Nov-01, Volume: 131, Issue:21

    Topics: 4-Butyrolactone; Citric Acid Cycle; Drug Overdose; Europe; Humans; Illicit Drugs; Norway; Sodium Oxybate; Solvents; Substance Withdrawal Syndrome; Substance-Related Disorders

2011
The clinical toxicology of γ-hydroxybutyrate, γ-butyrolactone and 1,4-butanediol.
    Clinical toxicology (Philadelphia, Pa.), 2012, Volume: 50, Issue:6

    Topics: 4-Butyrolactone; Antidotes; Butylene Glycols; Charcoal; Humans; Sodium Oxybate; Substance Withdrawal Syndrome; Therapeutic Irrigation; Tissue Distribution

2012
Gamma-butyrolactone and 1,4-butanediol: abused analogues of gamma-hydroxybutyrate.
    Toxicological reviews, 2004, Volume: 23, Issue:1

    Topics: 4-Butyrolactone; Body Temperature Regulation; Butylene Glycols; GABA Modulators; Humans; Illicit Drugs; Seizures; Sodium Oxybate; Substance Withdrawal Syndrome; Substance-Related Disorders

2004
The gamma-hydroxybutyrate withdrawal syndrome.
    Toxicological reviews, 2004, Volume: 23, Issue:1

    Topics: 4-Butyrolactone; Humans; Sodium Oxybate; Substance Withdrawal Syndrome; Substance-Related Disorders

2004
Gamma-hydroxybutyric acid.
    The New England journal of medicine, 2005, Jun-30, Volume: 352, Issue:26

    Topics: 4-Butyrolactone; Animals; Butylene Glycols; Humans; Hydroxybutyrates; Receptors, Cell Surface; Receptors, Dopamine; Receptors, GABA; Substance Withdrawal Syndrome; Substance-Related Disorders

2005
Withdrawal from gamma-hydroxybutyrate, 1,4-butanediol and gamma-butyrolactone: a case report and systematic review.
    CJEM, 2008, Volume: 10, Issue:1

    Topics: 4-Butyrolactone; Adult; Butylene Glycols; Humans; Illicit Drugs; Male; Rhabdomyolysis; Seizures; Sodium Oxybate; Substance Withdrawal Syndrome

2008
The effect of chronic ethanol administration on central neurotransmitter mechanisms.
    Medical biology, 1979, Volume: 57, Issue:4

    Topics: 4-Butyrolactone; Animals; Aromatic-L-Amino-Acid Decarboxylases; Behavior, Animal; Brain; Catecholamines; Dihydroxyphenylalanine; Dopamine; Ethanol; gamma-Aminobutyric Acid; Humans; Male; Mice; Neurons; Neurotransmitter Agents; Norepinephrine; Propranolol; Rats; Receptors, Cholinergic; Receptors, Dopamine; Substance Withdrawal Syndrome; Synaptic Transmission; Time Factors

1979

Other Studies

19 other study(ies) available for 4-butyrolactone and Drug Withdrawal Symptoms

ArticleYear
[A case of severe rhabdomyolysis after γ-butyrolactone withdrawal].
    Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases, 2022, Jul-20, Volume: 40, Issue:7

    Topics: 4-Butyrolactone; Humans; Rhabdomyolysis; Solvents; Substance Withdrawal Syndrome

2022
Inpatient GHB withdrawal management in an inner-city hospital in Sydney, Australia: a retrospective medical record review.
    Psychopharmacology, 2023, Volume: 240, Issue:1

    Topics: 4-Butyrolactone; Baclofen; Delirium; Diazepam; Female; Hospitals, Urban; Humans; Inpatients; Male; Medical Records; Prospective Studies; Retrospective Studies; Sodium Oxybate; Substance Withdrawal Syndrome

2023
Inpatient management of GHB/GBL withdrawal.
    Psychiatria Danubina, 2019, Volume: 31, Issue:Suppl 3

    Topics: 4-Butyrolactone; Humans; Inpatients; Retrospective Studies; Sodium Oxybate; Substance Withdrawal Syndrome

2019
Psychiatric aspects of acute withdrawal from gamma-hydroxybutyrate (GHB) and its analogue gamma-butyrolactone (GBL): implications for psychiatry services in the general hospital.
    International journal of psychiatry in clinical practice, 2013, Volume: 17, Issue:2

    Topics: 4-Butyrolactone; Adult; Anxiety; Disease Management; Emergency Service, Hospital; Female; Hospitals, General; Humans; Male; Mental Health Services; Psychomotor Agitation; Sodium Oxybate; Substance Withdrawal Syndrome; Symptom Assessment

2013
Severe delirium of uncertain origin in a german psychiatric unit - caused by gamma-butyrolactone withdrawal.
    Pharmacopsychiatry, 2008, Volume: 41, Issue:5

    Topics: 4-Butyrolactone; Adult; Delirium; Germany; Humans; Male; Mental Disorders; Psychiatric Department, Hospital; Solvents; Substance Withdrawal Syndrome

2008
["Liquid ecstasy": gamma-butyrolactone withdrawal delirium with rhabdomyolysis and dialysis dependent renal failure].
    Deutsche medizinische Wochenschrift (1946), 2009, Volume: 134, Issue:18

    Topics: 4-Butyrolactone; Acute Kidney Injury; Adrenergic alpha-Agonists; Benzodiazepines; Clonidine; GABA Modulators; Humans; Intubation, Intratracheal; Male; Midazolam; Myoclonus; Renal Dialysis; Respiration, Artificial; Respiratory Insufficiency; Rhabdomyolysis; Solvents; Substance Withdrawal Syndrome; Young Adult

2009
A 16-year-old boy with severe gamma-butyrolactone (GBL) withdrawal delirium.
    Pharmacopsychiatry, 2009, Volume: 42, Issue:5

    Topics: 4-Butyrolactone; Adolescent; Central Nervous System Agents; Delirium; Humans; Male; Substance Withdrawal Syndrome; Treatment Outcome

2009
Bupropion-associated premature ejaculation.
    Pharmacopsychiatry, 2010, Volume: 43, Issue:4

    Topics: 4-Butyrolactone; Adolescent; Bupropion; Dopamine Uptake Inhibitors; Ejaculation; Humans; Male; Solvents; Substance Withdrawal Syndrome

2010
Gamma-butyrolactone (GBL) dependence and withdrawal.
    Addiction (Abingdon, England), 2011, Volume: 106, Issue:2

    Topics: 4-Butyrolactone; Adult; Ambulatory Care; Baclofen; Delirium; Diazepam; Dose-Response Relationship, Drug; Female; Hospitalization; Humans; Male; Muscle Relaxants, Central; Outpatient Clinics, Hospital; Recurrence; Solvents; Substance Withdrawal Syndrome; Substance-Related Disorders; Treatment Outcome; Young Adult

2011
A case of γ-butyrolactone associated with severe withdrawal delirium and acute renal failure.
    European addiction research, 2011, Volume: 17, Issue:4

    Topics: 4-Butyrolactone; Acute Kidney Injury; Delirium; Humans; Male; Severity of Illness Index; Substance Withdrawal Syndrome; Young Adult

2011
Neuroleptic malignant syndrome-like reaction precipitated by antipsychotics in a patient with gamma-butyrolactone withdrawal.
    Journal of addiction medicine, 2011, Volume: 5, Issue:4

    Topics: 4-Butyrolactone; Adult; Antipsychotic Agents; Clonazepam; Diagnosis, Differential; Drug Evaluation, Preclinical; Drug Therapy, Combination; Female; Hallucinations; Humans; Infusions, Intravenous; Injections, Intramuscular; Loxapine; Neuroleptic Malignant Syndrome; Psychomotor Agitation; Solvents; Substance Withdrawal Syndrome; Substance-Related Disorders

2011
Unusual presentation of a patient with GBL withdrawal: a case report.
    Psychiatria Danubina, 2011, Volume: 23 Suppl 1

    Topics: 4-Butyrolactone; Adult; Akathisia, Drug-Induced; Antipsychotic Agents; Chlorpromazine; Delirium; Hallucinations; Haloperidol; Humans; Hypnotics and Sedatives; Illicit Drugs; Lorazepam; Male; Substance Withdrawal Syndrome

2011
[Acute gamma-butyrolactone poisoning with withdrawal syndrome].
    Przeglad lekarski, 2011, Volume: 68, Issue:8

    Topics: 4-Butyrolactone; Adult; Coma; Humans; Male; Solvents; Substance Abuse Detection; Substance Withdrawal Syndrome

2011
[Withdrawal syndrome from abusive consumption of liquid ecstasy precursors].
    Medicina clinica, 2012, Jul-07, Volume: 139, Issue:4

    Topics: 4-Butyrolactone; Adult; Confusion; Humans; Illicit Drugs; Male; Psychomotor Agitation; Substance Withdrawal Syndrome

2012
Chronic intragastric administration of gamma-butyrolactone produces physical dependence in baboons.
    Psychopharmacology, 2006, Volume: 189, Issue:1

    Topics: 4-Butyrolactone; Animals; Behavior, Animal; Catheters, Indwelling; Conditioning, Operant; Dose-Response Relationship, Drug; Flumazenil; Food; GABA Antagonists; GABA-A Receptor Antagonists; GABA-B Receptor Antagonists; Male; Motor Skills; Muscle Relaxation; Organophosphorus Compounds; Papio anubis; Receptors, GABA-A; Receptors, GABA-B; Sleep; Sodium Oxybate; Substance Withdrawal Syndrome; Substance-Related Disorders; Time Factors

2006
Evaluation for the withdrawal syndrome from gamma-hydroxybutyric acid (GHB), gamma-butyrolactone (GBL), and 1,4-butanediol (1,4-BD) in different rat lines.
    Annals of the New York Academy of Sciences, 2006, Volume: 1074

    Topics: 4-Butyrolactone; Animals; Behavior, Animal; Butylene Glycols; Female; Hydroxybutyrates; Rats; Rats, Inbred Strains; Rats, Sprague-Dawley; Rats, Wistar; Seizures; Substance Withdrawal Syndrome

2006
Therapeutic gamma-hydroxybutyric acid monitoring in plasma and urine by gas chromatography-mass spectrometry.
    Journal of pharmaceutical and biomedical analysis, 1993, Volume: 11, Issue:6

    Topics: 4-Butyrolactone; Alcoholism; Drug Monitoring; Ethanol; Gas Chromatography-Mass Spectrometry; Humans; Regression Analysis; Sensitivity and Specificity; Sodium Oxybate; Substance Withdrawal Syndrome

1993
A case of withdrawal from the GHB precursors gamma-butyrolactone and 1,4-butanediol.
    The Journal of emergency medicine, 2001, Volume: 21, Issue:1

    Topics: 4-Butyrolactone; Adult; Anticonvulsants; Diazepam; Drug Therapy, Combination; Emergencies; Humans; Lorazepam; Male; Phenobarbital; Substance Withdrawal Syndrome; United States

2001
Pentobarbital for severe gamma-butyrolactone withdrawal.
    Annals of emergency medicine, 2001, Volume: 38, Issue:6

    Topics: 4-Butyrolactone; Adult; Arousal; Autonomic Nervous System Diseases; Emergency Service, Hospital; Female; Humans; Illicit Drugs; Male; Pentobarbital; Psychoses, Substance-Induced; Substance Withdrawal Syndrome; Treatment Outcome

2001