4-butyrolactone has been researched along with Colonic Neoplasms in 24 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (4.17) | 18.7374 |
| 1990's | 6 (25.00) | 18.2507 |
| 2000's | 6 (25.00) | 29.6817 |
| 2010's | 11 (45.83) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Araújo, AJ; Costa-Lotufo, LV; Lima, KSB; Marinho-Filho, JDB; Moraes, MO; Moura, AF; Pessoa, C; Pessoa, ODL; Silveira, ER; Sousa, TS | 1 |
| Bach Knudsen, KE; Herzig, KH; Klintrup, K; Mäkelä, J; Mäkinen, MJ; Mutt, SJ; Nørskov, NP; Sirniö, P; Tuomisto, A; Väyrynen, JP | 1 |
| Baghy, K; Boldizsár, I; Kovalszky, I; Mervai, Z; Molnár-Perl, I; Noszál, B; Sólyomváry, A; Tóth, G | 1 |
| Liu, J; Luo, Y; Ni, Y; Qian, X; Tao, S; Zhao, R | 1 |
| Bach Knudsen, KE; Christensen, J; Egeberg, R; Johnsen, NF; Loft, S; Olsen, A; Overvad, K; Thomsen, BL; Tjønneland, A | 1 |
| Chopade, BA; Ghosh, S; Pawar, VU; Shinde, VS | 1 |
| Ayella, A; Iwamoto, T; Jiang, Y; Lim, S; Lin, D; Tomich, J; Wang, W | 1 |
| Bandey, AH; Chashoo, G; Mondhe, D; Qazi, GN; Qazi, NA; Reddy, DM; Sampath Kumar, HM; Sawant, SD; Saxena, A; Saxena, AK; Sethi, VK; Shankar, M; Singh, SK; Srinivas, J; Taneja, SC; Verma, M | 1 |
| Avila, J; Cerda-García-Rojas, CM; García-Mauriño, S; Gómez-Hurtado, MA; Hernández-Hernández, JD; Joseph-Nathan, P; Manríquez-Torres, JJ; Motilva, V; Román-Marín, LU; Talero, E; Torres-Valencia, JM; Valdez-Calderón, A; Velázquez-Jiménez, R | 1 |
| Bocca, C; Bozzo, F; Ievolella, M; Miglietta, A | 1 |
| Ghidoni, R; Khalilzadeh, MA; Rajabi, M; Santaniello, E; Signorelli, P; Tavakolinia, F | 1 |
| Marshall, JA; Paige, MA; Piettre, A; Valeriote, F | 1 |
| Ireland, CM; Richardson, AD | 1 |
| Angelino, NJ; Chow, KC; Dolnick, BJ; Dolnick, R; Stephanie, LV; Sufrin, JR; Wu, Q | 1 |
| Das, SK; Horinaka, M; Kanazawa, K; Maoka, T; Nishino, H; Sakai, T; Satomi, Y; Wakada, M; Yoshida, T | 1 |
| Accioly, MT; Bozza, PT; Carrossini, N; Kaufmann, C; Maya-Monteiro, CM; Morgado-Diaz, JA; Oliveira, SS; Pacheco, P; Robbs, BK; Viola, JP | 1 |
| Adlercreutz, H | 1 |
| Hara, A; Hirose, Y; Kawamori, T; Mori, H; Satoh, K; Tamai, Y; Tanaka, T; Torihara, M; Yamahara, J | 1 |
| Ramírez, C; Rodríguez, AD | 1 |
| Gu, Z; Hopp, DC; McLaughlin, JL; Zeng, L | 1 |
| Akiyama, T; Nakajima, M; Okuyama, A | 1 |
| Kawabata, K; Matsunaga, K; Mori, H; Morishita, Y; Sugie, S; Tanaka, T; Yoshimi, N | 1 |
| Ikeda, K; Izawa, H; Miyoshi, H; Monden, M; Monden, T; Ohnishi, T; Sekimoto, M; Tomita, N; Tsujie, M; Yamamoto, H | 1 |
| Boyd, MR; McKee, TC; Meragelman, KM | 1 |
1 review(s) available for 4-butyrolactone and Colonic Neoplasms
| Article | Year |
|---|---|
[CDK and MMP inhibitors].
Topics: 4-Butyrolactone; Animals; Antineoplastic Agents; Colonic Neoplasms; Cyclin-Dependent Kinases; Dipeptides; Doxorubicin; Enzyme Inhibitors; Fibrosarcoma; Humans; Metalloendopeptidases; Mice; Mice, Nude; Protease Inhibitors; Succinates | 1997 |
23 other study(ies) available for 4-butyrolactone and Colonic Neoplasms
| Article | Year |
|---|---|
In vitro antitumor effect of a lignan isolated from Combretum fruticosum, trachelogenin, in HCT-116 human colon cancer cells.
Topics: 4-Butyrolactone; Antineoplastic Agents, Phytogenic; Autophagosomes; Autophagy; Beclin-1; Brazil; Cell Line; Cell Line, Tumor; Cell Survival; Colonic Neoplasms; Combretum; Drug Discovery; Ethnopharmacology; HCT116 Cells; Humans; Inhibitory Concentration 50; Medicine, Traditional; Microtubule-Associated Proteins; Molecular Structure; Neoplasm Proteins; Plant Stems; Vacuoles | 2018 |
Serum enterolactone concentrations are low in colon but not in rectal cancer patients.
Topics: 4-Butyrolactone; Aged; Case-Control Studies; Colon; Colonic Neoplasms; Diet, Western; Dietary Fiber; Feeding Behavior; Female; Gastrointestinal Microbiome; Healthy Volunteers; Humans; Intestinal Mucosa; Lignans; Male; Middle Aged; Rectal Neoplasms; Rectum; Risk Factors | 2019 |
Endogenous enzyme-hydrolyzed fruit of Cirsium brachycephalum: optimal source of the antiproliferative lignan trachelogenin regulating the Wnt/β-catenin signaling pathway in the SW480 colon adenocarcinoma cell line.
Topics: 4-Butyrolactone; Adenocarcinoma; Antineoplastic Agents, Phytogenic; beta Catenin; Cell Line, Tumor; Cirsium; Colonic Neoplasms; Fruit; Glycogen Synthase Kinase 3; Humans; Lignans; Molecular Structure; Proto-Oncogene Proteins c-myc; Wnt Signaling Pathway | 2015 |
Paraoxonase 2 modulates a proapoptotic function in LS174T cells in response to quorum sensing molecule N-(3-oxododecanoyl)-L-homoserine lactone.
Topics: 4-Butyrolactone; Acetylcysteine; Apoptosis; Aryldialkylphosphatase; beta-Cyclodextrins; Cell Line, Tumor; Cell Survival; Colonic Neoplasms; Gene Expression Regulation, Neoplastic; HCT116 Cells; Homoserine; Humans; Microscopy, Electron, Transmission; Mitochondria; Mucin-2; Quorum Sensing | 2016 |
Plasma enterolactone and risk of colon and rectal cancer in a case-cohort study of Danish men and women.
Topics: 4-Butyrolactone; Case-Control Studies; Cohort Studies; Colonic Neoplasms; Denmark; Feeding Behavior; Female; Humans; Life Style; Lignans; Male; Middle Aged; Phytoestrogens; Rectal Neoplasms; Risk Factors | 2010 |
Design and synthesis of harzialactone analogues: promising anticancer agents.
Topics: 4-Butyrolactone; Antineoplastic Agents; Cell Line, Tumor; Colonic Neoplasms; Drug Design; Drug Screening Assays, Antitumor; Female; Glucose; Humans; Lactones; Oxidation-Reduction; Stereoisomerism; Structure-Activity Relationship; Uterine Cervical Neoplasms | 2010 |
Cytostatic inhibition of cancer cell growth by lignan secoisolariciresinol diglucoside.
Topics: 4-Butyrolactone; Adenocarcinoma; Anticarcinogenic Agents; Butylene Glycols; Cell Cycle; Cell Line, Tumor; Chromatography, High Pressure Liquid; Colonic Neoplasms; Cyclin A; Cytostatic Agents; Dietary Carbohydrates; Dose-Response Relationship, Drug; Glucosides; Glycosides; Humans; Lignans; Mass Spectrometry | 2010 |
Design and synthesis of spiro derivatives of parthenin as novel anti-cancer agents.
Topics: 4-Butyrolactone; Animals; Antineoplastic Agents; Blotting, Western; Carcinoma, Ehrlich Tumor; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; DNA Fragmentation; Humans; Male; Mice; Neoplasm Transplantation; NF-kappa B; Nitriles; Oxides; Prostatic Neoplasms; Sesquiterpenes; Spiro Compounds; Structure-Activity Relationship | 2011 |
Absolute configuration of podophyllotoxin related lignans from Bursera fagaroides using vibrational circular dichroism.
Topics: 4-Butyrolactone; Adenocarcinoma; Antineoplastic Agents, Phytogenic; Benzofurans; Bursera; Cell Line, Tumor; Circular Dichroism; Colonic Neoplasms; Dioxoles; Drugs, Chinese Herbal; Humans; Magnetic Resonance Spectroscopy; Molecular Structure; Phytotherapy; Plant Extracts; Plant Exudates; Podophyllotoxin | 2011 |
A novel nitro-oxy substituted analogue of rofecoxib reduces human colon cancer cell growth.
Topics: 4-Butyrolactone; Antineoplastic Agents; beta Catenin; Cadherins; Cell Line, Tumor; Cell Proliferation; Cell Survival; Colonic Neoplasms; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Gene Expression; Humans; Mitogen-Activated Protein Kinases; Nitrates; Phosphorylation; Proto-Oncogene Proteins c-myc | 2012 |
Naphthalene-fused (α-alkoxycarbonyl)methylene-γ-butyrolactones: antiproliferative activity and binding to bovine serum albumin and DNA.
Topics: 4-Butyrolactone; Animals; Antineoplastic Agents; Breast Neoplasms; Cattle; Cell Proliferation; Colonic Neoplasms; DNA; Female; Humans; Molecular Structure; Naphthalenes; Naphthols; Serum Albumin, Bovine; Structure-Activity Relationship; Tumor Cells, Cultured | 2012 |
Total synthesis and structure confirmation of the annonaceous acetogenins 30(S)-hydroxybullatacin, uvarigrandin a, and 5(R)-uvarigrandin a (narumicin I?).
Topics: 4-Butyrolactone; Antineoplastic Agents, Phytogenic; Catalysis; Colonic Neoplasms; Drug Screening Assays, Antitumor; Furans; Humans; Indicators and Reagents; Lactones; Magnetic Resonance Spectroscopy; Molecular Structure; Stereoisomerism; Tumor Cells, Cultured | 2003 |
A profile of the in vitro antitumor activity of lissoclinolide.
Topics: 4-Butyrolactone; Animals; Antineoplastic Agents; Cell Division; Cell Survival; Colonic Neoplasms; Drug Screening Assays, Antitumor; HCT116 Cells; Humans; Inhibitory Concentration 50; Urochordata | 2004 |
Enhancement of 5-fluorouracil sensitivity by an rTS signaling mimic in H630 colon cancer cells.
Topics: 4-Butyrolactone; Antineoplastic Combined Chemotherapy Protocols; Biomimetic Materials; Cell Line, Tumor; Colonic Neoplasms; Down-Regulation; Drug Synergism; Fluorouracil; Homoserine; Humans; Isoenzymes; Phosphorylation; Protein Isoforms; RNA, Antisense; Signal Transduction; Thymidylate Synthase; Tubulin | 2005 |
Halocynthiaxanthin and peridinin sensitize colon cancer cell lines to tumor necrosis factor-related apoptosis-inducing ligand.
Topics: 4-Butyrolactone; Apoptosis; Carotenoids; Caspase Inhibitors; Cell Line, Tumor; Colonic Neoplasms; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Humans; Poly(ADP-ribose) Polymerases; Signal Transduction; TNF-Related Apoptosis-Inducing Ligand; Xanthophylls | 2007 |
Lipid bodies are reservoirs of cyclooxygenase-2 and sites of prostaglandin-E2 synthesis in colon cancer cells.
Topics: 4-Butyrolactone; Adenocarcinoma; Aspirin; Caco-2 Cells; Cell Growth Processes; Colonic Neoplasms; Cyclooxygenase 2; Dinoprostone; HCT116 Cells; HT29 Cells; Humans; Lipid Metabolism; Organelles; Subcellular Fractions | 2008 |
Does fiber-rich food containing animal lignan precursors protect against both colon and breast cancer? An extension of the "fiber hypothesis".
Topics: 4-Butyrolactone; Breast Neoplasms; Chemical Phenomena; Chemistry; Colonic Neoplasms; Dietary Fiber; Estrogens; Female; Humans; Lignans; Male; Plant Extracts | 1984 |
Suppression of azoxymethane-induced colonic aberrant crypt foci by dietary exposure to a novel synthesized retinoidal butenolide, 5-hydroxy-4-(2-phenyl-(E)ethenyl)-2(5H)-furanone, in rats.
Topics: 4-Butyrolactone; Animals; Anticarcinogenic Agents; Azoxymethane; Biogenic Polyamines; Biomarkers, Tumor; Body Weight; Cell Division; Colonic Neoplasms; Epithelium; Intestinal Mucosa; Liver; Male; Nucleolus Organizer Region; Organ Size; Ornithine Decarboxylase; Rats; Rats, Inbred F344; Retinoids; Silver Staining | 1995 |
Further butenolides from the Caribbean octocoral Pterogorgia citrina.
Topics: 4-Butyrolactone; Animals; Cnidaria; Colonic Neoplasms; Drug Screening Assays, Antitumor; Escherichia coli; Furans; Humans; Magnetic Resonance Spectroscopy; Microbial Sensitivity Tests; Tumor Cells, Cultured | 1994 |
Squamotacin: an annonaceous acetogenin with cytotoxic selectivity for the human prostate tumor cell line (PC-3).
Topics: 4-Butyrolactone; Animals; Antineoplastic Agents, Phytogenic; Artemia; Breast Neoplasms; Colonic Neoplasms; Humans; Kidney Neoplasms; Lung Neoplasms; Male; Pancreatic Neoplasms; Plants, Medicinal; Prostatic Neoplasms; Tumor Cells, Cultured | 1996 |
Regressive effects of various chemopreventive agents on azoxymethane-induced aberrant crypt foci in the rat colon.
Topics: 4-Butyrolactone; Animals; Anticarcinogenic Agents; Azoxymethane; Body Weight; Carcinogens; Chemoprevention; Chlorogenic Acid; Colonic Neoplasms; Drug Administration Schedule; Male; Methyl Methanesulfonate; Piroxicam; Rats; Rats, Inbred F344; Retinoids | 1997 |
Cdk2/cdc2 expression in colon carcinogenesis and effects of cdk2/cdc2 inhibitor in colon cancer cells.
Topics: 4-Butyrolactone; Adenoma; Antineoplastic Agents; Apoptosis; Carcinoma; CDC2 Protein Kinase; CDC2-CDC28 Kinases; Cell Division; Colonic Neoplasms; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinases; Enzyme Inhibitors; Humans; Protein Serine-Threonine Kinases; Tumor Cells, Cultured | 1998 |
10-Demethoxystegane, a new lignan from Steganotaenia araliacea.
Topics: 4-Butyrolactone; Antineoplastic Agents, Phytogenic; Apiaceae; Chromatography, High Pressure Liquid; Colonic Neoplasms; Female; Humans; Inhibitory Concentration 50; Lignans; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Ovarian Neoplasms; Plants, Medicinal; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet; Tumor Cells, Cultured | 2001 |