Compounds > 4-butyrolactone
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4-butyrolactone and Cancer of Prostate

4-butyrolactone has been researched along with Cancer of Prostate in 40 studies

Research

Studies (40)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (7.50)18.2507
2000's16 (40.00)29.6817
2010's18 (45.00)24.3611
2020's3 (7.50)2.80

Authors

AuthorsStudies
Chen, YJ; Chung, CH; Hsueh, TY; Huang, TF; Lai, YW; Lin, CC; Lin, CH; Liu, SC; Wang, SW1
Bhupathiraju, NVSDK; Gonzalez Periche, P; Johnson, DS; Kalidindi, T; Mootoo, DR; Pillarsetty, N; Ramdular, A1
Hu, M; Long, H; Lu, J; Ma, F; Ma, J; Mei, J; Qin, Z; Tao, N; Wang, Y1
Bolvig, AK; Christensen, J; Eriksen, AK; Kyrø, C; Landberg, R; Nørskov, N; Olsen, A; Overvad, K; Tjønneland, A1
Adlercreutz, H; Bjartell, A; Drake, I; Gullberg, B; Olsson, H; Sonestedt, E; Tikkanen, MJ; Wallström, P; Wirfält, E1
Bryan, JN; Eaton, AM; Gajagowni, S; Kumar, SR; Robinson, KL1
Hu, M; Long, H; Ma, F; Ma, J; Qin, Z; Tao, N; Wang, Y; Xu, Y; Zheng, Q1
Conney, AH; Huang, Y; Khor, TO; Kong, AN; Lee, JH; Saw, CL; Shu, L; Su, ZY; Suh, N; Wu, Q; Wu, TY; Yang, CS1
Azrad, M; Brenner, DE; Demark-Wahnefried, W; Dewhirst, M; Madden, J; Moul, JW; Polascik, TJ; Ruffin, MT; Snyder, DC; Vollmer, RT1
Gunter, JH; Lubik, AA; Nelson, CC; Pouwer, RH; Quinn, RJ; Sadowski, MC1
McCann, MJ; Rowland, IR; Roy, NC2
Babich, JW; Haberkorn, U; Mairs, RJ; Rae, C1
Adlercreutz, H; Dillner, J; Gislefoss, R; Hakama, M; Hallmans, G; Langseth, H; Lumme, S; Luostarinen, T; Saikku, P; Stattin, P; Stenman, UH; Tenkanen, L; Tuohimaa, P1
Fuks, Z; Haimovitz-Friedman, A; Kang, JH; Kolesnick, R; Lerman, G; Marquez, VE; Rotenberg, SA; Truman, JP1
Chen, LH; Demark-Wahnefried, W; Fang, J; Li, H; Lin, X; Sun, Z; Wu, Y1
Chen, SP; Chen, YL; Chiu, SC; Harn, HJ; Huang, SY; Lin, SZ; Pang, CY; Wang, MJ; Yang, HH1
Bandey, AH; Chashoo, G; Mondhe, D; Qazi, GN; Qazi, NA; Reddy, DM; Sampath Kumar, HM; Sawant, SD; Saxena, A; Saxena, AK; Sethi, VK; Shankar, M; Singh, SK; Srinivas, J; Taneja, SC; Verma, M1
El Sayed, KA; Hassan, HM; Hifnawy, MS; Mohammed, R; Sallam, AA; Youssef, DT1
Caggia, S; Cardile, V; Garbarino, J; Piovano, M; Russo, A1
Habib, FK; Halley, L; Ho, CK; Wei, J1
Chen, XG; Huang, WB; Jia, RP; Li, WC; Qian, M; Wu, JP; Xu, LW; Xu, Z1
Chiou, TW; Chou, YW; Harn, HJ; Huang, MH; Lin, CT; Lin, PC; Lin, SZ; Liu, PY; Sheu, JJ1
Arisaka, O; Evans, BA; Miyake, N; Morgan, LD; Morton, MS1
Adlercreutz, H; Albanes, D; Kilkkinen, A; Pietinen, P; Virtamo, J; Virtanen, MJ1
Juang, JL; Lin, H; Wang, PS1
Adlercreutz, H; Auprich, M; Brössner, C; Fink, K; Madersbacher, S; Petritsch, K; Petritsch, P; Rehak, P1
Adlercreutz, H; Biessy, C; Bylund, A; Hallmans, G; Kaaks, R; Stattin, P1
Adami, HO; Adlercreutz, H; Andersson, SO; Bälter, KA; Bellocco, R; Chang, ET; Grönberg, H; Hedelin, M; Heinonen, SM; Johansson, JE; Klint, A1
Alexander, FE; Bolton-Smith, C; Heald, CL; Morton, MS; Ritchie, MR1
Chen, LH; Demark-Wahnefried, W; Fang, J; Li, H; Lin, X1
Adlercreutz, H2
Lewis, JS; Vāvere, AL1
Berrar, D; Gill, CI; Linton, T; McCann, MJ; McGlynn, H; Rowland, IR1
Gu, Z; Hopp, DC; McLaughlin, JL; Zeng, L1
Alali, F; Kim, GS; McLaughlin, JL; Rogers, LL; Sastrodihardjo, S; Wu, FE; Zeng, L1
Goto, T; Hosaka, Y; Kawabe, K; Kitamura, T; Matsushima, H; Suzuki, M1
Bova, GS; Han, WF; Nelson, JB; Pflug, BR; Pizer, ES; Udan, MS1
Adlercreutz, H; Dillner, J; Hakama, M; Hallmans, G; Harvei, S; Jellum, E; Lehtinen, M; Lumme, S; Luostarinen, T; Stattin, P; Stumpf, K; Tenkanen, L; Teppo, L1

Reviews

2 review(s) available for 4-butyrolactone and Cancer of Prostate

ArticleYear
Lignans and human health.
    Critical reviews in clinical laboratory sciences, 2007, Volume: 44, Issue:5-6

    Topics: 4-Butyrolactone; Animals; Cardiovascular Diseases; Colorectal Neoplasms; Dietary Fiber; Edible Grain; Endometrial Neoplasms; Feeding Behavior; Female; Health Status; Humans; Isoflavones; Lignans; Male; Phytoestrogens; Plants, Edible; Prostatic Neoplasms; Seeds; Vegetables

2007
Phyto-oestrogens and cancer.
    The Lancet. Oncology, 2002, Volume: 3, Issue:6

    Topics: 4-Butyrolactone; Animals; Breast Neoplasms; Diet; Estrogens, Non-Steroidal; Female; Glycine max; Humans; Isoflavones; Lignans; Male; Neoplasms; Phytoestrogens; Plant Preparations; Prostatic Neoplasms; Tumor Cells, Cultured

2002

Trials

1 trial(s) available for 4-butyrolactone and Cancer of Prostate

ArticleYear
Flaxseed-derived enterolactone is inversely associated with tumor cell proliferation in men with localized prostate cancer.
    Journal of medicinal food, 2013, Volume: 16, Issue:4

    Topics: 4-Butyrolactone; Aged; Antineoplastic Agents, Phytogenic; Biomarkers; Cell Proliferation; Dietary Supplements; Flax; Humans; Ki-67 Antigen; Lignans; Male; Middle Aged; Phytotherapy; Plant Extracts; Prostatic Neoplasms; Vascular Endothelial Growth Factor A

2013

Other Studies

37 other study(ies) available for 4-butyrolactone and Cancer of Prostate

ArticleYear
4-Acetylantroquinonol B Suppresses Prostate Cancer Growth and Angiogenesis via a VEGF/PI3K/ERK/mTOR-Dependent Signaling Pathway in Subcutaneous Xenograft and In Vivo Angiogenesis Models.
    International journal of molecular sciences, 2022, Jan-27, Volume: 23, Issue:3

    Topics: 4-Butyrolactone; Angiogenesis Inhibitors; Cell Movement; Cell Proliferation; Cell Survival; Cyclohexanones; Gene Expression Regulation, Neoplastic; Human Umbilical Vein Endothelial Cells; Humans; Male; PC-3 Cells; Phosphatidylinositol 3-Kinase; Prostatic Neoplasms; Proto-Oncogene Proteins c-akt; Signal Transduction; TOR Serine-Threonine Kinases; Vascular Endothelial Growth Factor A; Xenograft Model Antitumor Assays

2022
Synthesis of carbohydrate analogues of the THF-acetogenin 4-deoxyannomontacin and their cytotoxicity against human prostate cancer cell lines.
    Carbohydrate research, 2022, Volume: 521

    Topics: 4-Butyrolactone; Acetogenins; Alkenes; Antineoplastic Agents; Carbohydrates; Cell Line, Tumor; Humans; Male; Mannose; Prostatic Neoplasms; Thiophenes; Trichothecenes

2022
Ligustilide promotes apoptosis of cancer-associated fibroblasts via the TLR4 pathways.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2020, Volume: 135

    Topics: 4-Butyrolactone; Animals; Apoptosis; Cancer-Associated Fibroblasts; Cell Cycle; Cell Proliferation; Heterografts; Humans; Male; Mice; Mice, Inbred C57BL; Prostatic Neoplasms; Toll-Like Receptor 4; Tumor Microenvironment

2020
Prediagnostic enterolactone concentrations and mortality among Danish men diagnosed with prostate cancer.
    European journal of clinical nutrition, 2017, Volume: 71, Issue:10

    Topics: 4-Butyrolactone; Adult; Cohort Studies; Denmark; Diet; Early Detection of Cancer; Humans; Lignans; Male; Middle Aged; Proportional Hazards Models; Prostatic Neoplasms; Registries; Risk Factors; Survival Analysis; White People

2017
Plasma enterolactone and risk of prostate cancer in middle-aged Swedish men.
    European journal of nutrition, 2018, Volume: 57, Issue:7

    Topics: 4-Butyrolactone; Case-Control Studies; Humans; Life Style; Lignans; Male; Middle Aged; Prostatic Neoplasms; Risk Factors; Sweden

2018
Differential Modulation of Transcription Factors and Cytoskeletal Proteins in Prostate Carcinoma Cells by a Bacterial Lactone.
    BioMed research international, 2018, Volume: 2018

    Topics: 4-Butyrolactone; Apoptosis; Bacterial Proteins; Carcinoma; Cell Line, Tumor; Cell Movement; Cell Survival; Cytoskeletal Proteins; Epithelial Cells; Humans; Lactones; Male; Phosphorylation; Prostatic Neoplasms; STAT1 Transcription Factor; Transcription Factors

2018
Ligustilide inhibits the activation of cancer-associated fibroblasts.
    Life sciences, 2019, Feb-01, Volume: 218

    Topics: 4-Butyrolactone; Apoptosis; Cancer-Associated Fibroblasts; Cell Proliferation; Humans; Male; Prostatic Neoplasms; Signal Transduction; Tumor Cells, Cultured

2019
Epigenetic reactivation of Nrf2 in murine prostate cancer TRAMP C1 cells by natural phytochemicals Z-ligustilide and Radix angelica sinensis via promoter CpG demethylation.
    Chemical research in toxicology, 2013, Mar-18, Volume: 26, Issue:3

    Topics: 4-Butyrolactone; Angelica sinensis; Animals; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Cell Survival; CpG Islands; DNA Methylation; Drugs, Chinese Herbal; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Male; Mice; NF-E2-Related Factor 2; Promoter Regions, Genetic; Prostate; Prostatic Neoplasms

2013
The fatty acid synthase inhibitor triclosan: repurposing an anti-microbial agent for targeting prostate cancer.
    Oncotarget, 2014, Oct-15, Volume: 5, Issue:19

    Topics: 3T3 Cells; 4-Butyrolactone; Animals; Anti-Infective Agents, Local; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Drug Repositioning; Fatty Acid Synthase, Type I; Fatty Acid Synthesis Inhibitors; G1 Phase Cell Cycle Checkpoints; Humans; Lactones; Lipid Metabolism; Male; Mice; Orlistat; Prostatic Neoplasms; Structure-Activity Relationship; Triclosan

2014
The anti-proliferative effects of enterolactone in prostate cancer cells: evidence for the role of DNA licencing genes, mi-R106b cluster expression, and PTEN dosage.
    Nutrients, 2014, Nov-03, Volume: 6, Issue:11

    Topics: 4-Butyrolactone; Cell Line, Tumor; Cell Proliferation; Cell Survival; Gene Expression Regulation, Neoplastic; Humans; Lignans; Male; MicroRNAs; Mitochondria; Prostatic Neoplasms; PTEN Phosphohydrolase; RNA, Messenger

2014
Inhibition of Fatty Acid Synthase Sensitizes Prostate Cancer Cells to Radiotherapy.
    Radiation research, 2015, Volume: 184, Issue:5

    Topics: 4-Butyrolactone; Antioxidants; Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Movement; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fatty Acid Synthases; Humans; Male; Prostatic Neoplasms; Radiation Tolerance; Spheroids, Cellular; X-Rays

2015
Longitudinal biobanks-based study on the joint effects of infections, nutrition and hormones on risk of prostate cancer.
    Acta oncologica (Stockholm, Sweden), 2016, Volume: 55, Issue:7

    Topics: 4-Butyrolactone; Adult; Blood Banks; Case-Control Studies; Chlamydia Infections; Chlamydia trachomatis; Cohort Studies; Finland; Human papillomavirus 18; Humans; Lignans; Longitudinal Studies; Male; Middle Aged; Norway; Papillomavirus Infections; Prostatic Neoplasms; Risk Factors; Sweden; Testosterone; Vitamin D

2016
PKCalpha activation downregulates ATM and radio-sensitizes androgen-sensitive human prostate cancer cells in vitro and in vivo.
    Cancer biology & therapy, 2009, Volume: 8, Issue:1

    Topics: 4-Butyrolactone; Androgens; Apoptosis; Ataxia Telangiectasia Mutated Proteins; Cell Cycle Proteins; Cell Division; Cell Line, Tumor; DNA-Binding Proteins; Down-Regulation; Enzyme Activation; Humans; Kinetics; Male; Prostatic Neoplasms; Protein Kinase C-alpha; Protein Serine-Threonine Kinases; Tetradecanoylphorbol Acetate; Tumor Suppressor Proteins; Valerates

2009
Enterolactone inhibits insulin-like growth factor-1 receptor signaling in human prostatic carcinoma PC-3 cells.
    The Journal of nutrition, 2009, Volume: 139, Issue:4

    Topics: 4-Butyrolactone; Cell Line, Tumor; Cell Movement; Cell Proliferation; Gene Expression Regulation, Neoplastic; Humans; Insulin-Like Growth Factor I; Lignans; Male; Phosphotyrosine; Prostatic Neoplasms; Proto-Oncogene Proteins c-akt; Receptor, IGF Type 1; Signal Transduction

2009
Activation of NAG-1 via JNK signaling revealed an isochaihulactone-triggered cell death in human LNCaP prostate cancer cells.
    BMC cancer, 2011, Apr-20, Volume: 11

    Topics: 4-Butyrolactone; Anthracenes; Benzodioxoles; Blotting, Western; CDC2 Protein Kinase; cdc25 Phosphatases; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cyclin B1; Cyclin-Dependent Kinase Inhibitor p21; Dose-Response Relationship, Drug; Early Growth Response Protein 1; Growth Differentiation Factor 15; Humans; JNK Mitogen-Activated Protein Kinases; Male; Mitogen-Activated Protein Kinase 8; Mitogen-Activated Protein Kinase 9; Phosphorylation; Prostatic Neoplasms; Proto-Oncogene Proteins c-bcl-2; RNA Interference; Signal Transduction; Tumor Suppressor Protein p53

2011
Design and synthesis of spiro derivatives of parthenin as novel anti-cancer agents.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:8

    Topics: 4-Butyrolactone; Animals; Antineoplastic Agents; Blotting, Western; Carcinoma, Ehrlich Tumor; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; DNA Fragmentation; Humans; Male; Mice; Neoplasm Transplantation; NF-kappa B; Nitriles; Oxides; Prostatic Neoplasms; Sesquiterpenes; Spiro Compounds; Structure-Activity Relationship

2011
Semisynthetic analogues of the marine cembranoid sarcophine as prostate and breast cancer migration inhibitors.
    Bioorganic & medicinal chemistry, 2011, Aug-15, Volume: 19, Issue:16

    Topics: 4-Butyrolactone; Animals; Anthozoa; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Migration Assays; Cell Migration Inhibition; Cell Proliferation; Diterpenes; Drug Screening Assays, Antitumor; Female; Humans; Indian Ocean; Male; Prostatic Neoplasms; Structure-Activity Relationship

2011
Effect of vicanicin and protolichesterinic acid on human prostate cancer cells: role of Hsp70 protein.
    Chemico-biological interactions, 2012, Jan-05, Volume: 195, Issue:1

    Topics: 4-Butyrolactone; Antineoplastic Agents; Apoptosis; Caspase 3; Cell Line, Tumor; Cell Survival; Comet Assay; Depsides; DNA Fragmentation; Gene Expression Regulation, Neoplastic; HSP70 Heat-Shock Proteins; Humans; Hydroxybenzoates; L-Lactate Dehydrogenase; Lactones; Male; Prostatic Neoplasms; Reactive Oxygen Species

2012
Analysis of prostate cancer association with four single-nucleotide polymorphisms from genome-wide studies and serum phyto-estrogen concentrations.
    Prostate cancer and prostatic diseases, 2012, Volume: 15, Issue:4

    Topics: 4-Butyrolactone; Aged; Alleles; Genetic Association Studies; Genetic Predisposition to Disease; Humans; Lignans; Male; Middle Aged; Polymorphism, Single Nucleotide; Prostatic Neoplasms; Risk Factors; Scotland

2012
Expression and significance of microsomal prostaglandin synthase-1 (mPGES-1) and Beclin-1 in the development of prostate cancer.
    Asian Pacific journal of cancer prevention : APJCP, 2012, Volume: 13, Issue:4

    Topics: 4-Butyrolactone; Adenocarcinoma; Age Factors; Aged; Aged, 80 and over; Analysis of Variance; Apoptosis Regulatory Proteins; Beclin-1; Cell Line, Tumor; Cell Proliferation; Cell Survival; Chi-Square Distribution; Humans; Intramolecular Oxidoreductases; Male; Membrane Proteins; Microsomes; Middle Aged; Neoplasm Grading; Neoplasm Staging; Prostaglandin-E Synthases; Prostate; Prostatic Hyperplasia; Prostatic Neoplasms; Thiophenes; Up-Regulation

2012
Regulation of androgen receptor expression by Z-isochaihulactone mediated by the JNK signaling pathway and might be related to cytotoxicity in prostate cancer.
    The Prostate, 2013, Volume: 73, Issue:5

    Topics: 4-Butyrolactone; Animals; Antineoplastic Agents; Apoptosis; Benzodioxoles; Cell Line, Tumor; Cytotoxins; Gene Expression Regulation, Neoplastic; Green Fluorescent Proteins; Humans; Male; MAP Kinase Signaling System; Mice; Mice, Inbred BALB C; Mice, Nude; Prostatic Neoplasms; Receptors, Androgen; Transcription, Genetic; Xenograft Model Antitumor Assays

2013
Anti-proliferative effects of physiological concentrations of enterolactone in models of prostate tumourigenesis.
    Molecular nutrition & food research, 2013, Volume: 57, Issue:2

    Topics: 4-Butyrolactone; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cell Transformation, Neoplastic; DNA Replication; Humans; Lignans; Male; Mitochondria; Prostatic Neoplasms; Real-Time Polymerase Chain Reaction

2013
Phytoestrogen concentrations in serum from Japanese men and women over forty years of age.
    The Journal of nutrition, 2002, Volume: 132, Issue:10

    Topics: 4-Butyrolactone; Adult; Aged; Aged, 80 and over; Breast Neoplasms; Chromans; Diet; Equol; Estrogens, Non-Steroidal; Female; Gas Chromatography-Mass Spectrometry; Genistein; Humans; Isoflavones; Japan; Lignans; Male; Middle Aged; Phytoestrogens; Plant Preparations; Prostatic Neoplasms; United Kingdom

2002
Serum enterolactone concentration is not associated with prostate cancer risk in a nested case-control study.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2003, Volume: 12, Issue:11 Pt 1

    Topics: 4-Butyrolactone; Aged; Case-Control Studies; Fluoroimmunoassay; Humans; Lignans; Male; Middle Aged; Odds Ratio; Prostatic Neoplasms; Risk Factors

2003
Involvement of Cdk5/p25 in digoxin-triggered prostate cancer cell apoptosis.
    The Journal of biological chemistry, 2004, Jul-09, Volume: 279, Issue:28

    Topics: 4-Butyrolactone; Apoptosis; Calcium; Caspase Inhibitors; Caspases; Cell Line, Tumor; Cyclin-Dependent Kinase 5; Cyclin-Dependent Kinases; Digoxin; Dipeptides; Enzyme Activation; Enzyme Inhibitors; Humans; Male; Nerve Tissue Proteins; Prostatic Neoplasms; Purines; RNA, Small Interfering; Roscovitine

2004
Phytoestrogen tissue levels in benign prostatic hyperplasia and prostate cancer and their association with prostatic diseases.
    Urology, 2004, Volume: 64, Issue:4

    Topics: 4-Butyrolactone; Adenocarcinoma; Aged; Aged, 80 and over; Diet; Genistein; Humans; Lignans; Male; Middle Aged; Organ Size; Phytoestrogens; Prostate; Prostatic Hyperplasia; Prostatic Neoplasms

2004
Prospective study of plasma enterolactone and prostate cancer risk (Sweden).
    Cancer causes & control : CCC, 2004, Volume: 15, Issue:10

    Topics: 4-Butyrolactone; Cohort Studies; Humans; Life Style; Lignans; Male; Middle Aged; Obesity; Phytoestrogens; Prospective Studies; Prostatic Neoplasms; Risk; Smoking; Sweden

2004
Dietary phytoestrogen, serum enterolactone and risk of prostate cancer: the cancer prostate Sweden study (Sweden).
    Cancer causes & control : CCC, 2006, Volume: 17, Issue:2

    Topics: 4-Butyrolactone; Diet; Health Behavior; Humans; Life Style; Lignans; Male; Phytoestrogens; Prostatic Neoplasms; Risk Factors; Sweden

2006
Phyto-oestrogens and risk of prostate cancer in Scottish men.
    The British journal of nutrition, 2007, Volume: 98, Issue:2

    Topics: 4-Butyrolactone; Aged; Case-Control Studies; Diet; Diet Surveys; Energy Intake; Equol; Genistein; Humans; Isoflavones; Lignans; Male; Middle Aged; Phytoestrogens; Prostatic Neoplasms; Risk Assessment; Scotland

2007
Enterolactone induces apoptosis in human prostate carcinoma LNCaP cells via a mitochondrial-mediated, caspase-dependent pathway.
    Molecular cancer therapeutics, 2007, Volume: 6, Issue:9

    Topics: 4-Butyrolactone; Apoptosis; Caspases; Cell Survival; Cytochromes c; Enzyme Activation; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Immunoblotting; In Situ Nick-End Labeling; Lignans; Male; Membrane Potential, Mitochondrial; Mitochondria; Phytoestrogens; Poly(ADP-ribose) Polymerases; Prostatic Neoplasms; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-mdm2; Tumor Cells, Cultured; Tumor Suppressor Protein p53

2007
Examining the relationship between Cu-ATSM hypoxia selectivity and fatty acid synthase expression in human prostate cancer cell lines.
    Nuclear medicine and biology, 2008, Volume: 35, Issue:3

    Topics: 4-Butyrolactone; Cell Hypoxia; Cell Line, Tumor; Coordination Complexes; Copper Radioisotopes; Dose-Response Relationship, Drug; Drug Synergism; Fatty Acid Synthases; Gene Expression; Humans; Male; Organometallic Compounds; Positron-Emission Tomography; Prostatic Neoplasms; Radiopharmaceuticals; Thiosemicarbazones

2008
Enterolactone restricts the proliferation of the LNCaP human prostate cancer cell line in vitro.
    Molecular nutrition & food research, 2008, Volume: 52, Issue:5

    Topics: 4-Butyrolactone; Cell Division; Cell Line, Tumor; Cell Survival; Humans; Lignans; Male; Mitochondria; Phytoestrogens; Polymerase Chain Reaction; Prostate-Specific Antigen; Prostatic Neoplasms

2008
Squamotacin: an annonaceous acetogenin with cytotoxic selectivity for the human prostate tumor cell line (PC-3).
    Journal of natural products, 1996, Volume: 59, Issue:2

    Topics: 4-Butyrolactone; Animals; Antineoplastic Agents, Phytogenic; Artemia; Breast Neoplasms; Colonic Neoplasms; Humans; Kidney Neoplasms; Lung Neoplasms; Male; Pancreatic Neoplasms; Plants, Medicinal; Prostatic Neoplasms; Tumor Cells, Cultured

1996
Muricoreacin and murihexocin C, mono-tetrahydrofuran acetogenins, from the leaves of Annona muricata.
    Phytochemistry, 1998, Volume: 49, Issue:2

    Topics: 4-Butyrolactone; Adenocarcinoma; Antineoplastic Agents, Phytogenic; Chromatography, High Pressure Liquid; Fatty Alcohols; Furans; Humans; Lactones; Magnetic Resonance Spectroscopy; Male; Pancreatic Neoplasms; Plant Extracts; Plant Leaves; Plants, Medicinal; Prostatic Neoplasms; Spectrometry, Mass, Fast Atom Bombardment; Trees; Tumor Cells, Cultured

1998
Butyrolactone I induces cyclin B1 and causes G2/M arrest and skipping of mitosis in human prostate cell lines.
    Cancer letters, 1999, Apr-26, Volume: 138, Issue:1-2

    Topics: 4-Butyrolactone; Cell Survival; Cyclin B; Cyclin B1; Cyclin-Dependent Kinases; DNA, Neoplasm; Enzyme Inhibitors; G2 Phase; Humans; Male; Mitosis; Prostatic Neoplasms; Tumor Cells, Cultured

1999
Increased fatty acid synthase as a therapeutic target in androgen-independent prostate cancer progression.
    The Prostate, 2001, May-01, Volume: 47, Issue:2

    Topics: 4-Butyrolactone; Androgens; Animals; Antibodies, Monoclonal; Antineoplastic Agents; Blotting, Western; Chromatography, Thin Layer; Enzyme Inhibitors; Fatty Acid Synthases; Humans; Immunohistochemistry; Lipids; Male; Mice; Mice, Nude; Neoplasms, Hormone-Dependent; Prostatic Neoplasms; Random Allocation; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2001
Circulating enterolactone and prostate cancer risk: a Nordic nested case-control study.
    International journal of cancer, 2002, May-01, Volume: 99, Issue:1

    Topics: 4-Butyrolactone; Case-Control Studies; Cohort Studies; Estrogens; Finland; Fluoroimmunoassay; Humans; Lignans; Male; Middle Aged; Norway; Prospective Studies; Prostatic Neoplasms; Risk Factors; Sweden

2002