Compounds > 4-butyrolactone
Page last updated: 2024-08-18

4-butyrolactone and Breast Cancer

4-butyrolactone has been researched along with Breast Cancer in 79 studies

Research

Studies (79)

TimeframeStudies, this research(%)All Research%
pre-19903 (3.80)18.7374
1990's8 (10.13)18.2507
2000's33 (41.77)29.6817
2010's33 (41.77)24.3611
2020's2 (2.53)2.80

Authors

AuthorsStudies
Becher, H; Behrens, S; Chang-Claude, J; Gonzalez-Maldonado, S; Hell, R; Huebner, M; Hüsing, A; Jaskulski, S; Jung, AY; Obi, N; Poschet, G1
Chen, WY; Cuyàs, E; Lupu, R; Menendez, JA; Papadimitropoulou, A; Peirce, SK; Steen, TV; Vellon, L; Verdura, S1
Dou, G; He, H; Li, J; Li, L; Ma, H; Qi, H; Wang, C; Wu, M1
He, H; Jiang, Z; Li, L; Qi, H; Wang, C; Yang, Y; Yu, Z1
Balhouse, BN; Patterson, L; Schmelz, EM; Slade, DJ; Verbridge, SS1
Chang-Claude, J; Herpel, E; Jaskulski, S; Johnson, T; Jung, AY; Rudolph, A; Sinn, P; Thöne, K1
Bach Knudsen, KE; Eriksen, AK; Frederiksen, K; Hansen, L; Holm, M; Kyrø, C; Nørskov, NP; Olsen, A; Tjønneland, A1
Behrens, S; Chang-Claude, J; Flesch-Janys, D; Jaskulski, S; Johnson, T; Jung, AY; Kaaks, R; Sookthai, D; Thöne, K1
Abrahamsson, A; Dabrosin, C; Lindahl, G1
Engel, N; Falodun, A; Kragl, U; Langer, P; Nebe, B1
Ishiguro, H; Takeuchi, M; Tanaka, S; Toi, M; Tsuji, W; Ueno, T1
Eliassen, AH; Franke, AA; Hankinson, SE; Rice, MS; Rosner, BA; Terry, KL; Tworoger, SS; Willett, WC; Xie, J1
Behrens, S; Buck, K; Chang-Claude, J; Flesch-Janys, D; Heinz, J; Johnson, TS; Kaaks, R; Linseisen, J; Obi, N; Seibold, P; Vrieling, A1
Alhammady, MA; El-Beih, AA; Elkhateeb, A; Gamal-Eldeen, AM; Hegazy, ME; Ohta, S; Paré, PW1
Bessadóttir, M; Eccles, S; Gowan, S; Ogmundsdóttir, HM; Ögmundsdóttir, S; Skúladóttir, EÁ1
Hu, XJ; Li, Y; Liu, CM; Xiong, XY1
Cunha, NL; Dos Santos, RA; Gonçalves, Ndos S; Martins, TD; Oliveira, PF; Rezende, KC; Silva, ML; Símaro, GV; Souza, AR; Souza, DG; Tavares, DC; Teixeira, GM1
Albanell, J; Arenas, EJ; Beltran, A; García-Rocha, M; Gomis, RR; Guinovart, JJ; Guiu, M; Lluch, A; Planet, E; Rojo, F; Rovira, A; Salvatella, X; Samino, S; Slebe, F; Testoni, G; Vinaixa, M; Yanes, O1
Goswami, S; Sharma-Walia, N1
Fu, Q; Hu, Y; Lv, Q; Qiu, J; Tan, Q; Tang, S; Yang, J; Zhang, J; Zhou, Y1
Buxó, M; Corominas-Faja, B; Cuyàs, E; García, J; Lupu, R; Martin-Castillo, B; Menendez, JA; Serra, D; Vellon, L1
Bigdeli, B; Goliaei, B; Haghparast, A; Jooyan, N; Mamashli, F; Masoudi-Khoram, N; Nikoofar, A; Rouhani, M1
Adlercreutz, H; Borgquist, S; Ericson, U; Gullberg, B; Landberg, G; Olsson, H; Sonestedt, E; Wirfält, E1
Adlercreutz, H; Carlson, J; Ericson, U; Gullberg, B; Harlid, S; Ivarsson, MI; Olsson, H; Sonestedt, E; Wirfält, E1
Abrahamsson, A; Dabrosin, C; Saarinen, NM1
Baek, JM; Boulbes, D; Esteva, FJ; Gomez-Cabello, D; Hawke, DH; Hortobagyi, GN; Hung, MC; Jin, Q; Lee, MH; Wang, YN; Yeung, SC; Yuan, LX1
Abrahamsson, A; Dabrosin, C; Lindahl, G; Saarinen, N1
Christensen, J; Johnsen, NF; Knudsen, KE; Olsen, A; Overvad, K; Tjønneland, A1
Cufí, S; Del Barco, S; Martin-Castillo, B; Menendez, JA; Oliveras-Ferraros, C; Sauri-Nadal, T; Vazquez-Martin, A1
Becker, S; Buck, K; Chang-Claude, J; Flesch-Janys, D; Kaaks, R; Linseisen, J; Vrieling, A; Zaineddin, AK1
El Sayed, KA; Hassan, HM; Hifnawy, MS; Mohammed, R; Sallam, AA; Youssef, DT1
Patterson, RE1
Becker, S; Buck, K; Chang-Claude, J; Flesch-Janys, D; Hüsing, A; Kaaks, R; Linseisen, J; Vrieling, A; Zaineddin, AK1
Abarzua, S; Briese, V; Piechulla, B; Richter, DU; Serikawa, T; Szewczyk, M1
Ghidoni, R; Khalilzadeh, MA; Rajabi, M; Santaniello, E; Signorelli, P; Tavakolinia, F1
Boccardo, F; Guglielmini, P; Rubagotti, A1
Buck, K; Chang-Claude, J; Flesch-Janys, D; Heinz, J; Linseisen, J; Vrieling, A; Zaineddin, AK1
Adlercreutz, H; Hallmans, G; Hultén, K; Johansson, R; Lenner, P; Winkvist, A1
Ambrosone, CB; Freudenheim, JL; McCann, SE; Moysich, KB; Shields, PG1
Arisaka, O; Evans, BA; Miyake, N; Morgan, LD; Morton, MS1
Grobbee, DE; Keinan-Boker, L; Peeters, PH; van der Schouw, YT1
Boccardo, F; Lunardi, GL; Petti, AR; Rubagotti, A1
Chen, J; Thompson, LU1
Kuhajda, FP; McFadden, JM; Medghalchi, SM; Pinn, ML; Ronnett, GV; Simpson, PJ; Townsend, CA; Vadlamudi, A; Zhou, W1
Adlercreutz, H; Kilkkinen, A; Pietinen, P; Sankila, R; Vartiainen, E; Virtamo, J; Virtanen, MJ1
Boccardo, F; Guglielmini, P; Lunardi, G; Murialdo, R; Parodi, M; Rubagotti, A; Schettini, G1
Chhabra, SR; Hooi, D; Li, L; Pritchard, D; Shaw, PE1
Adlercreutz, H; Arslan, AA; Kato, I; Koenig, KL; Shore, RE; Toniolo, P; Zeleniuch-Jacquotte, A1
Colomer, R; Lupu, R; Mehmi, I; Menendez, JA; Oza, BP; Ropero, S; Vellon, L1
Lupu, R; Mehmi, I; Menendez, JA; Teng, PK; Verma, VA1
Knudsen, KE; Loft, S; Møller, S; Olsen, A; Overvad, K; Stripp, C; Thomsen, BL; Tjønneland, A1
Brooks, JD; Thompson, LU1
Boccardo, F; Guglielmini, P; Puntoni, M; Rubagotti, A1
Adlercreutz, H; Bremnes, Y; Gram, IT; Stuedal, A; Ursin, G; Veierød, MB1
Chang-Claude, J; Linseisen, J; Piller, R1
Chang-Claude, J; Linseisen, J; Piller, R; Verla-Tebit, E; Wang-Gohrke, S1
Bergman Jungeström, M; Dabrosin, C; Thompson, LU1
Bombelli, R; Cosentino, M; Crema, F; Delle Canne, MG; Ferrari, M; Lecchini, S; Legnaro, M; Luini, A; Luzzani, M; Marino, F; Paracchini, S; Rasini, E1
Airio, M; Mäkelä, S; Saarinen, NM; Smeds, A; Wärri, A1
Brunet, J; Colomer, R; Menendez, JA; Vazquez-Martin, A1
Brunet, J; Casals, G; Colomer, R; Haro, D; Marrero, PF; Menéndez, JA; Pétriz, J; Porta, R; Puig, T; Relat, J; Vázquez-Martín, A1
Antignac, JP; Dip, R; Gmuender, H; Le Bizec, B; Lenz, S; Naegeli, H1
Chen, CY; Hsu, YL; Kuo, PL; Lin, CC; Tzeng, TF1
Bennetau-Pelissero, C; Carreau, C; Flouriot, G; Potier, M1
Adlercreutz, H; Dwyer, JT; Fotsis, T; Goldin, BR; Gorbach, SL; Heikkinen, R; Woods, M1
Adlercreutz, H2
Fang, XP; Gu, ZM; McLaughlin, JL; Rieser, MJ; Wood, KV; Zeng, L1
Gu, Z; Hopp, DC; McLaughlin, JL; Zeng, L1
Ingram, D; Kolybaba, M; Lopez, D; Sanders, K1
Kurzer, MS; Wang, C1
Adlercreutz, H; Akhmedkhanov, A; Toniolo, P; Zeleniuch-Jacquotte, A1
Fu, LW; Huang, HB; Liang, YJ; Pan, QC1
Adlercreut, H; Hallmans, G; Hultén, K; Kilkkinen, A; Mazur, W; Pietinen, P; Stumpf, K1
Adlercreutz, H; Arts, CJ; den Tonkelaar, I; Keinan-Boker, L; Peeters, PH; Thijssen, JH; Veer, PV1
Adlercreutz, H; Kataja, V; Männistö, S; Pietinen, P; Stumpf, K; Uusitupa, M1
Adlercreutz, H; Mousavi, Y1
Fukuoka, K; Hirano, T; Hosaka, K; Matsumoto, Y; Mitsuhashi, H; Naito, T; Oka, K1
Calaf, G; Jordan, VC; Koch, R; Murphy, CS; Welshons, WV1

Reviews

8 review(s) available for 4-butyrolactone and Breast Cancer

ArticleYear
Enterolactone concentrations and prognosis after postmenopausal breast cancer: assessment of effect modification and meta-analysis.
    International journal of cancer, 2014, Aug-15, Volume: 135, Issue:4

    Topics: 4-Butyrolactone; Aged; Biomarkers, Tumor; Body Mass Index; Breast Neoplasms; Diet; Disease Progression; Disease-Free Survival; Female; Germany; Humans; Life Style; Lignans; Middle Aged; Postmenopause; Prognosis; Proportional Hazards Models; Prospective Studies; Risk Factors

2014
Gastrointestinal microbiome and breast cancer: correlations, mechanisms and potential clinical implications.
    Breast cancer (Tokyo, Japan), 2017, Volume: 24, Issue:2

    Topics: 4-Butyrolactone; Animals; Breast Neoplasms; Diet; Estrogens; Female; Gastrointestinal Microbiome; Humans; Lignans; Obesity

2017
Serum enterolactone and postmenopausal breast cancer risk by estrogen, progesterone and herceptin 2 receptor status.
    International journal of cancer, 2012, Mar-15, Volume: 130, Issue:6

    Topics: 4-Butyrolactone; Breast Neoplasms; Case-Control Studies; Cohort Studies; Estrogens; Humans; Lignans; Logistic Models; Middle Aged; Postmenopause; Progesterone; Prospective Studies; Receptor, ErbB-2; Receptors, Estrogen; Receptors, Progesterone; Risk Factors

2012
Phytoestrogens and breast cancer risk. Review of the epidemiological evidence.
    Breast cancer research and treatment, 2003, Volume: 77, Issue:2

    Topics: 4-Butyrolactone; Adolescent; Adult; Age Factors; Breast Neoplasms; Case-Control Studies; Climacteric; Diet; Estrogens; Estrogens, Non-Steroidal; Female; Glycine max; Humans; Isoflavones; Lignans; Male; Phytoestrogens; Plant Preparations; Plants; Prospective Studies; Risk

2003
Enterolactone as a risk factor for breast cancer: a review of the published evidence.
    Clinica chimica acta; international journal of clinical chemistry, 2006, Volume: 365, Issue:1-2

    Topics: 4-Butyrolactone; Breast Neoplasms; Diet; Humans; Lignans; Risk Factors

2006
Role of dietary lignans in the reduction of breast cancer risk.
    Molecular nutrition & food research, 2007, Volume: 51, Issue:7

    Topics: 4-Butyrolactone; Animals; Anticarcinogenic Agents; Bacteria; Breast Neoplasms; Cell Division; Diet; Female; Humans; Intestines; Lignans; Mammary Neoplasms, Animal; Plants, Edible; Risk Factors

2007
Food containing phytoestrogens, and breast cancer.
    BioFactors (Oxford, England), 2000, Volume: 12, Issue:1-4

    Topics: 4-Butyrolactone; Animals; Breast Neoplasms; Edible Grain; Estrogens; Estrogens, Non-Steroidal; Female; Finland; Food; Humans; Isoflavones; Japan; Lignans; Phytoestrogens; Plant Preparations; Pregnancy; Prenatal Exposure Delayed Effects

2000
Phyto-oestrogens and cancer.
    The Lancet. Oncology, 2002, Volume: 3, Issue:6

    Topics: 4-Butyrolactone; Animals; Breast Neoplasms; Diet; Estrogens, Non-Steroidal; Female; Glycine max; Humans; Isoflavones; Lignans; Male; Neoplasms; Phytoestrogens; Plant Preparations; Prostatic Neoplasms; Tumor Cells, Cultured

2002

Trials

2 trial(s) available for 4-butyrolactone and Breast Cancer

ArticleYear
Orally administered S-1 suppresses circulating endothelial cell counts in metastatic breast cancer patients.
    International journal of clinical oncology, 2014, Volume: 19, Issue:3

    Topics: 4-Butyrolactone; Administration, Oral; Adult; Aged; Antigens, CD34; Antimetabolites, Antineoplastic; Breast Neoplasms; Cell Count; Chemokine CCL2; Drug Combinations; Endothelial Cells; Female; Fluorouracil; Humans; Middle Aged; Neovascularization, Pathologic; Oxonic Acid; Tegafur; Thrombospondin 1; Treatment Outcome; Vascular Endothelial Growth Factor A

2014
Enterolactone in breast cyst fluid: correlation with EGF and breast cancer risk.
    Breast cancer research and treatment, 2003, Volume: 79, Issue:1

    Topics: 4-Butyrolactone; Adult; Aged; Breast Neoplasms; Epidermal Growth Factor; Exudates and Transudates; Female; Fibrocystic Breast Disease; Humans; Lignans; Middle Aged; Odds Ratio; Predictive Value of Tests; Risk Factors; Statistics as Topic

2003

Other Studies

69 other study(ies) available for 4-butyrolactone and Breast Cancer

ArticleYear
Prognostic associations of circulating phytoestrogens and biomarker changes in long-term survivors of postmenopausal breast cancer.
    Nutrition and cancer, 2020, Volume: 72, Issue:7

    Topics: 4-Butyrolactone; Aged; Biomarkers, Tumor; Breast Neoplasms; Case-Control Studies; Cohort Studies; Female; Genistein; Germany; Humans; Lignans; Middle Aged; Phytoestrogens; Postmenopause; Prognosis; Proportional Hazards Models; Prospective Studies; Survival Analysis; Survivors

2020
Progesterone receptor isoform-dependent cross-talk between prolactin and fatty acid synthase in breast cancer.
    Aging, 2020, 12-10, Volume: 12, Issue:24

    Topics: 4-Butyrolactone; Breast Neoplasms; Carcinoma, Ductal, Breast; Cell Line, Tumor; Databases, Genetic; Fatty Acid Synthase, Type I; Humans; Interleukin-6; Prolactin; Promoter Regions, Genetic; Protein Isoforms; Receptor Cross-Talk; Receptors, Progesterone; Receptors, Prolactin; RNA, Messenger; Up-Regulation

2020
Z-ligustilide restores tamoxifen sensitivity of ERa negative breast cancer cells by reversing MTA1/IFI16/HDACs complex mediated epigenetic repression of ERa.
    Oncotarget, 2017, Apr-25, Volume: 8, Issue:17

    Topics: 4-Butyrolactone; Breast Neoplasms; Cell Line, Tumor; Epigenesis, Genetic; Epigenetic Repression; Female; Gene Expression Regulation, Neoplastic; Histone Deacetylase 1; Humans; Tamoxifen

2017
Sensitization of tamoxifen-resistant breast cancer cells by Z-ligustilide through inhibiting autophagy and accumulating DNA damages.
    Oncotarget, 2017, Apr-25, Volume: 8, Issue:17

    Topics: 4-Butyrolactone; Autophagy; Breast Neoplasms; Cell Line, Tumor; DNA Damage; Female; Humans; MCF-7 Cells

2017
N-(3-oxododecanoyl)-L-homoserine lactone interactions in the breast tumor microenvironment: Implications for breast cancer viability and proliferation in vitro.
    PloS one, 2017, Volume: 12, Issue:7

    Topics: 4-Butyrolactone; Breast Neoplasms; Cell Hypoxia; Cell Line, Tumor; Cell Proliferation; Cell Survival; Female; Homoserine; Humans; Necrosis; Tumor Microenvironment

2017
Genistein and enterolactone in relation to Ki-67 expression and HER2 status in postmenopausal breast cancer patients.
    Molecular nutrition & food research, 2017, Volume: 61, Issue:11

    Topics: 4-Butyrolactone; Aged; Breast Carcinoma In Situ; Breast Neoplasms; Case-Control Studies; Cell Proliferation; Female; Genistein; Germany; Humans; Isoflavones; Ki-67 Antigen; Lignans; Middle Aged; Neoplasm Grading; Neoplasm Invasiveness; Phytoestrogens; Postmenopause; Prognosis; Receptor, ErbB-2; Tumor Burden

2017
Pre-diagnostic plasma enterolactone concentrations and breast cancer prognosis among postmenopausal women - The Danish Diet, Cancer and Health cohort.
    Clinical nutrition (Edinburgh, Scotland), 2018, Volume: 37, Issue:6 Pt A

    Topics: 4-Butyrolactone; Aged; Breast Neoplasms; Cohort Studies; Denmark; Female; Humans; Lignans; Middle Aged; Phytoestrogens; Postmenopause; Prognosis

2018
Circulating enterolactone concentrations and prognosis of postmenopausal breast cancer: assessment of mediation by inflammatory markers.
    International journal of cancer, 2018, 12-01, Volume: 143, Issue:11

    Topics: 4-Butyrolactone; Aged; Biomarkers; Breast Neoplasms; Case-Control Studies; Disease-Free Survival; Female; Humans; Inflammation; Lignans; Middle Aged; Postmenopause; Prognosis; Proportional Hazards Models; Prospective Studies

2018
Dietary flaxseed and tamoxifen affect the inflammatory microenvironment in vivo in normal human breast tissue of postmenopausal women.
    European journal of clinical nutrition, 2019, Volume: 73, Issue:9

    Topics: 4-Butyrolactone; Breast; Breast Neoplasms; Diet; Estrogen Antagonists; Female; Flax; Humans; Inflammation; Interleukin 1 Receptor Antagonist Protein; Interleukin-18; Interleukin-1beta; Interleukin-8; Lignans; Matrix Metalloproteinase 9; Microdialysis; Middle Aged; Postmenopause; Seeds; Tamoxifen; Tumor Microenvironment

2019
Novel anticancer alkene lactone from Persea americana.
    Pharmaceutical biology, 2013, Volume: 51, Issue:6

    Topics: 4-Butyrolactone; Antineoplastic Agents, Phytogenic; Apoptosis; Breast Neoplasms; Cell Adhesion; Cell Proliferation; Dose-Response Relationship, Drug; Female; Flow Cytometry; Humans; Inhibitory Concentration 50; Integrins; MCF-7 Cells; Medicine, Traditional; Persea; Plant Bark; Plant Extracts; Plant Roots

2013
Plasma enterolactone and breast cancer risk in the Nurses' Health Study II.
    Breast cancer research and treatment, 2013, Volume: 139, Issue:3

    Topics: 4-Butyrolactone; Adult; Breast Neoplasms; Case-Control Studies; Cohort Studies; Diet; Estradiol; Female; Humans; Lignans; Multivariate Analysis; Nurses; Premenopause; Prospective Studies; Receptors, Estrogen; Receptors, Progesterone; United States; Vegetables

2013
New terpenes from the Egyptian soft coral Sarcophyton ehrenbergi.
    Marine drugs, 2014, Apr-02, Volume: 12, Issue:4

    Topics: 4-Butyrolactone; Adenocarcinoma; Animals; Anthozoa; Antineoplastic Agents; Breast Neoplasms; Carcinoma, Hepatocellular; Egypt; Hep G2 Cells; Humans; Liver Neoplasms; Magnetic Resonance Spectroscopy; MCF-7 Cells; Terpenes

2014
Effects of anti-proliferative lichen metabolite, protolichesterinic acid on fatty acid synthase, cell signalling and drug response in breast cancer cells.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2014, Oct-15, Volume: 21, Issue:12

    Topics: 4-Butyrolactone; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Drug Synergism; Fatty Acid Synthases; Female; Humans; Lapatinib; Lichens; Molecular Structure; Quinazolines; Receptor, ErbB-2; Signal Transduction

2014
Inhibitory Effects of Enterolactone on Growth and Metastasis in Human Breast Cancer.
    Nutrition and cancer, 2015, Volume: 67, Issue:8

    Topics: 4-Butyrolactone; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cyclins; Cytoskeleton; Focal Adhesion Kinase 1; Forkhead Box Protein M1; Forkhead Transcription Factors; Gene Expression; Humans; Ki-67 Antigen; Lignans; Neoplasm Invasiveness; Neoplasm Metastasis; Paxillin; Proliferating Cell Nuclear Antigen; RNA, Messenger; S Phase; Signal Transduction

2015
(-)-Hinokinin Induces G2/M Arrest and Contributes to the Antiproliferative Effects of Doxorubicin in Breast Cancer Cells.
    Planta medica, 2016, Volume: 82, Issue:6

    Topics: 4-Butyrolactone; Antineoplastic Combined Chemotherapy Protocols; Benzodioxoles; Breast Neoplasms; Caspase 3; Cell Line, Tumor; Cell Proliferation; Cell Survival; Doxorubicin; Female; G2 Phase Cell Cycle Checkpoints; Gene Expression Regulation, Neoplastic; Humans; Inhibitory Concentration 50; Lignans; M Phase Cell Cycle Checkpoints

2016
FoxA and LIPG endothelial lipase control the uptake of extracellular lipids for breast cancer growth.
    Nature communications, 2016, Apr-05, Volume: 7

    Topics: 4-Butyrolactone; Animals; Biological Transport; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Doxycycline; Enzyme Inhibitors; Female; Gene Expression Regulation, Neoplastic; Hepatocyte Nuclear Factor 3-alpha; Hepatocyte Nuclear Factor 3-beta; Humans; Lactones; Lipase; Lipid Metabolism; MCF-7 Cells; Mice; Mice, Nude; Neoplasm Invasiveness; Orlistat; RNA, Small Interfering; Signal Transduction; Xenograft Model Antitumor Assays

2016
Crosstalk between osteoprotegerin (OPG), fatty acid synthase (FASN) and, cycloxygenase-2 (COX-2) in breast cancer: implications in carcinogenesis.
    Oncotarget, 2016, Sep-13, Volume: 7, Issue:37

    Topics: 4-Butyrolactone; Breast Neoplasms; Carcinogenesis; Caspase 9; Celecoxib; Cell Line, Tumor; Cyclooxygenase 2 Inhibitors; Fatty Acid Synthases; Female; Humans; Lipid Droplets; Lipid Metabolism; Molecular Targeted Therapy; Osteoprotegerin; Protein Binding; Receptor Cross-Talk; Signal Transduction; Tumor Microenvironment

2016
Clinical and therapeutic relevance of the metabolic oncogene fatty acid synthase in HER2+ breast cancer.
    Histology and histopathology, 2017, Volume: 32, Issue:7

    Topics: 4-Butyrolactone; Antineoplastic Agents; Apoptosis; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Enzyme Inhibitors; Fatty Acid Synthase, Type I; Female; Gene Expression Regulation, Neoplastic; Humans; MCF-7 Cells; Oncogenes; Prognosis; Receptor, ErbB-2; Survival Analysis

2017
Enterolactone: A novel radiosensitizer for human breast cancer cell lines through impaired DNA repair and increased apoptosis.
    Toxicology and applied pharmacology, 2016, 12-15, Volume: 313

    Topics: 4-Butyrolactone; Apoptosis; Breast Neoplasms; Cell Line, Tumor; DNA Repair; Female; Humans; Lignans; Radiation-Sensitizing Agents

2016
Enterolactone is differently associated with estrogen receptor beta-negative and -positive breast cancer in a Swedish nested case-control study.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2008, Volume: 17, Issue:11

    Topics: 4-Butyrolactone; Adult; Aged; Biomarkers, Tumor; Breast Neoplasms; Case-Control Studies; Diet; Estrogen Receptor alpha; Estrogen Receptor beta; Female; Humans; Lignans; Linear Models; Microarray Analysis; Middle Aged; Obesity; Prospective Studies; Reproducibility of Results; Risk Assessment; Smoking; Surveys and Questionnaires; Sweden

2008
The protective association of high plasma enterolactone with breast cancer is reasonably robust in women with polymorphisms in the estrogen receptor alpha and beta genes.
    The Journal of nutrition, 2009, Volume: 139, Issue:5

    Topics: 4-Butyrolactone; Aged; Breast Neoplasms; Cohort Studies; Estrogen Receptor alpha; Estrogen Receptor beta; Female; Genetic Predisposition to Disease; Humans; Lignans; Middle Aged; Phytoestrogens; Polymorphism, Single Nucleotide; Prospective Studies

2009
Estrogen-induced angiogenic factors derived from stromal and cancer cells are differently regulated by enterolactone and genistein in human breast cancer in vivo.
    International journal of cancer, 2010, Aug-01, Volume: 127, Issue:3

    Topics: 4-Butyrolactone; Angiogenesis Inducing Agents; Animals; Breast Neoplasms; Cell Proliferation; Estrogens; Female; Genistein; Humans; Lignans; Mice; Mice, Nude; Stromal Cells; Vascular Endothelial Growth Factor A

2010
Fatty acid synthase phosphorylation: a novel therapeutic target in HER2-overexpressing breast cancer cells.
    Breast cancer research : BCR, 2010, Volume: 12, Issue:6

    Topics: 4-Butyrolactone; Antineoplastic Agents; Apoptosis; Blotting, Western; Breast Neoplasms; Cell Line, Tumor; Fatty Acid Synthases; Female; Fluorescent Antibody Technique; Gene Expression; Humans; Lapatinib; Mass Spectrometry; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Neuregulin-1; Phosphorylation; Protein Kinase Inhibitors; Quinazolines; Receptor, ErbB-2; RNA, Small Interfering; Signal Transduction

2010
Tamoxifen, flaxseed, and the lignan enterolactone increase stroma- and cancer cell-derived IL-1Ra and decrease tumor angiogenesis in estrogen-dependent breast cancer.
    Cancer research, 2011, Jan-01, Volume: 71, Issue:1

    Topics: 4-Butyrolactone; Animals; Antineoplastic Agents, Hormonal; Breast Neoplasms; Cell Division; Cell Line, Tumor; Estrogen Receptor alpha; Estrogens; Female; Flax; Humans; Immunohistochemistry; Interleukin 1 Receptor Antagonist Protein; Lignans; Macrophages; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasms, Hormone-Dependent; Neovascularization, Pathologic; Stromal Cells; Tamoxifen

2011
Prediagnostic plasma enterolactone levels and mortality among women with breast cancer.
    Breast cancer research and treatment, 2011, Volume: 128, Issue:3

    Topics: 4-Butyrolactone; Aged; Breast Neoplasms; Cohort Studies; Female; Humans; Lignans; Middle Aged; Neoplasm Staging; Prognosis; Receptors, Estrogen; Survival Analysis

2011
Circulating fatty acid synthase: an exploratory biomarker to predict efficacy of the dual HER1/HER2 tyrosine kinase inhibitor lapatinib.
    Breast cancer research : BCR, 2011, Jan-24, Volume: 13, Issue:1

    Topics: 4-Butyrolactone; Antineoplastic Agents; Breast Neoplasms; Fatty Acid Synthases; Female; Humans; Quinazolines; Receptor, ErbB-2

2011
Semisynthetic analogues of the marine cembranoid sarcophine as prostate and breast cancer migration inhibitors.
    Bioorganic & medicinal chemistry, 2011, Aug-15, Volume: 19, Issue:16

    Topics: 4-Butyrolactone; Animals; Anthozoa; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Migration Assays; Cell Migration Inhibition; Cell Proliferation; Diterpenes; Drug Screening Assays, Antitumor; Female; Humans; Indian Ocean; Male; Prostatic Neoplasms; Structure-Activity Relationship

2011
Flaxseed and breast cancer: what should we tell our patients?
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011, Oct-01, Volume: 29, Issue:28

    Topics: 4-Butyrolactone; Breast Neoplasms; Female; Humans; Lignans

2011
Serum enterolactone and prognosis of postmenopausal breast cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011, Oct-01, Volume: 29, Issue:28

    Topics: 4-Butyrolactone; Aged; Biomarkers, Tumor; Breast Neoplasms; Case-Control Studies; Female; Humans; Lignans; Middle Aged; Postmenopause; Prognosis

2011
Antiproliferative activity of lignans against the breast carcinoma cell lines MCF 7 and BT 20.
    Archives of gynecology and obstetrics, 2012, Volume: 285, Issue:4

    Topics: 4-Butyrolactone; Anticarcinogenic Agents; Breast Neoplasms; Butylene Glycols; Cell Line, Tumor; Cell Proliferation; Estradiol; Estrogens; Female; Furans; Humans; Lignans; Phytoestrogens; Selective Estrogen Receptor Modulators; Tamoxifen

2012
Naphthalene-fused (α-alkoxycarbonyl)methylene-γ-butyrolactones: antiproliferative activity and binding to bovine serum albumin and DNA.
    DNA and cell biology, 2012, Volume: 31, Issue:5

    Topics: 4-Butyrolactone; Animals; Antineoplastic Agents; Breast Neoplasms; Cattle; Cell Proliferation; Colonic Neoplasms; DNA; Female; Humans; Molecular Structure; Naphthalenes; Naphthols; Serum Albumin, Bovine; Structure-Activity Relationship; Tumor Cells, Cultured

2012
Serum enterolactone levels and mortality outcome in women with early breast cancer: a retrospective cohort study.
    Breast cancer research and treatment, 2012, Volume: 132, Issue:2

    Topics: 4-Butyrolactone; Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; Breast Neoplasms; Chemotherapy, Adjuvant; Female; Fluoroimmunoassay; Humans; Italy; Kaplan-Meier Estimate; Lignans; Mastectomy; Middle Aged; Proportional Hazards Models; Registries; Retrospective Studies; Risk Assessment; Risk Factors; Time Factors; Treatment Outcome; Up-Regulation

2012
The association between dietary lignans, phytoestrogen-rich foods, and fiber intake and postmenopausal breast cancer risk: a German case-control study.
    Nutrition and cancer, 2012, Volume: 64, Issue:5

    Topics: 4-Butyrolactone; Aged; Breast Neoplasms; Carcinoma; Case-Control Studies; Cucurbita; Diet; Dietary Fiber; Female; Germany; Glycine max; Helianthus; Humans; Lignans; Middle Aged; Phytoestrogens; Postmenopause; Risk; Seeds

2012
An incident case-referent study on plasma enterolactone and breast cancer risk.
    European journal of nutrition, 2002, Volume: 41, Issue:4

    Topics: 4-Butyrolactone; Aging; Breast Neoplasms; Cohort Studies; Dietary Fiber; Female; Humans; Lignans; Reference Values; Risk Factors; Surveys and Questionnaires

2002
The risk of breast cancer associated with dietary lignans differs by CYP17 genotype in women.
    The Journal of nutrition, 2002, Volume: 132, Issue:10

    Topics: 4-Butyrolactone; Adult; Aged; Breast Neoplasms; Case-Control Studies; Dose-Response Relationship, Drug; Female; Food Analysis; Genotype; Humans; Interviews as Topic; Lignans; Middle Aged; Odds Ratio; Premenopause; Risk Factors; Steroid 17-alpha-Hydroxylase

2002
Phytoestrogen concentrations in serum from Japanese men and women over forty years of age.
    The Journal of nutrition, 2002, Volume: 132, Issue:10

    Topics: 4-Butyrolactone; Adult; Aged; Aged, 80 and over; Breast Neoplasms; Chromans; Diet; Equol; Estrogens, Non-Steroidal; Female; Gas Chromatography-Mass Spectrometry; Genistein; Humans; Isoflavones; Japan; Lignans; Male; Middle Aged; Phytoestrogens; Plant Preparations; Prostatic Neoplasms; United Kingdom

2002
Lignans and tamoxifen, alone or in combination, reduce human breast cancer cell adhesion, invasion and migration in vitro.
    Breast cancer research and treatment, 2003, Volume: 80, Issue:2

    Topics: 4-Butyrolactone; Antineoplastic Agents; Breast Neoplasms; Cell Adhesion; Cell Line, Tumor; Cell Movement; Female; Humans; Lignans; Neoplasm Invasiveness; Neoplasm Metastasis; Phytotherapy; Receptors, Estrogen; Tamoxifen

2003
Fatty acid synthase inhibition triggers apoptosis during S phase in human cancer cells.
    Cancer research, 2003, Nov-01, Volume: 63, Issue:21

    Topics: 4-Butyrolactone; Apoptosis; Breast Neoplasms; Carnitine O-Palmitoyltransferase; Cell Division; Cell Line, Tumor; Drug Interactions; Epoxy Compounds; Fatty Acid Synthases; Furans; Humans; Membrane Lipids; Phospholipids; S Phase

2003
Serum enterolactone concentration is not associated with breast cancer risk in a nested case-control study.
    International journal of cancer, 2004, Jan-10, Volume: 108, Issue:2

    Topics: 4-Butyrolactone; Adult; Aged; Breast Neoplasms; Case-Control Studies; Cross-Sectional Studies; Estrogens; Female; Finland; Fluoroimmunoassay; Humans; Lignans; Middle Aged; Odds Ratio; Postmenopause; Premenopause; Prospective Studies; Risk Factors

2004
Serum enterolactone levels and the risk of breast cancer in women with palpable cysts.
    European journal of cancer (Oxford, England : 1990), 2004, Volume: 40, Issue:1

    Topics: 4-Butyrolactone; Adult; Aged; Biomarkers, Tumor; Breast Neoplasms; Female; Fibrocystic Breast Disease; Follow-Up Studies; Humans; Lignans; Middle Aged; Regression Analysis; Retrospective Studies; Risk Factors; Serum

2004
Bacterial N-acylhomoserine lactone-induced apoptosis in breast carcinoma cells correlated with down-modulation of STAT3.
    Oncogene, 2004, Jun-17, Volume: 23, Issue:28

    Topics: 4-Butyrolactone; Acute-Phase Proteins; Apoptosis; Breast Neoplasms; Cell Division; Cell Line, Tumor; DNA-Binding Proteins; Female; Gene Expression Regulation, Neoplastic; Humans; STAT3 Transcription Factor; Trans-Activators

2004
Circulating enterolactone and risk of breast cancer: a prospective study in New York.
    British journal of cancer, 2004, Jul-05, Volume: 91, Issue:1

    Topics: 4-Butyrolactone; Adult; Breast Neoplasms; Case-Control Studies; Estrogens; Female; Humans; Lignans; Middle Aged; New York; Odds Ratio; Postmenopause; Premenopause; Prospective Studies; Risk Factors

2004
Inhibition of fatty acid synthase (FAS) suppresses HER2/neu (erbB-2) oncogene overexpression in cancer cells.
    Proceedings of the National Academy of Sciences of the United States of America, 2004, Jul-20, Volume: 101, Issue:29

    Topics: 4-Butyrolactone; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antifungal Agents; Antineoplastic Agents; Apoptosis; Biomarkers, Tumor; Breast Neoplasms; Cell Line; Cell Size; Cell Survival; Cerulenin; Fatty Acid Synthases; Female; Gene Expression Regulation, Neoplastic; Genes, erbB-2; Humans; Ovarian Neoplasms; Receptor, ErbB-2; RNA, Small Interfering; Signal Transduction; Transcription Factors; Trastuzumab

2004
Pharmacological inhibition of fatty acid synthase (FAS): a novel therapeutic approach for breast cancer chemoprevention through its ability to suppress Her-2/neu (erbB-2) oncogene-induced malignant transformation.
    Molecular carcinogenesis, 2004, Volume: 41, Issue:3

    Topics: 4-Butyrolactone; Animals; Antifungal Agents; Apoptosis; Breast Neoplasms; Cell Adhesion; Cell Transformation, Neoplastic; Cells, Cultured; Cerulenin; Chemoprevention; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; fas Receptor; Fatty Acid Synthases; Fatty Acids; Fibroblasts; Gene Expression Regulation, Neoplastic; Humans; In Situ Nick-End Labeling; Mice; Mitogen-Activated Protein Kinases; NIH 3T3 Cells; Phosphatidylinositol 3-Kinases; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Receptor, ErbB-2; Receptors, Tumor Necrosis Factor

2004
Plasma enterolactone and breast cancer incidence by estrogen receptor status.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2004, Volume: 13, Issue:12

    Topics: 4-Butyrolactone; Breast Neoplasms; Case-Control Studies; Cohort Studies; Diet; Female; Humans; Life Style; Lignans; Middle Aged; Postmenopause; Receptors, Estrogen; Risk Factors

2004
Mammalian lignans and genistein decrease the activities of aromatase and 17beta-hydroxysteroid dehydrogenase in MCF-7 cells.
    The Journal of steroid biochemistry and molecular biology, 2005, Volume: 94, Issue:5

    Topics: 17-Hydroxysteroid Dehydrogenases; 4-Butyrolactone; Animals; Aromatase; Aromatase Inhibitors; Breast Neoplasms; Cell Line, Tumor; Estradiol; Female; Genistein; Humans; Lignans; Mammals; Phytoestrogens

2005
Plasma levels of enterolactone and percentage mammographic density among postmenopausal women.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2005, Volume: 14, Issue:9

    Topics: 4-Butyrolactone; Aged; Biomarkers; Body Mass Index; Breast Neoplasms; Cohort Studies; Female; Humans; Lignans; Mammography; Middle Aged; Postmenopause

2005
Plasma enterolactone and genistein and the risk of premenopausal breast cancer.
    European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP), 2006, Volume: 15, Issue:3

    Topics: 4-Butyrolactone; Adult; Breast Neoplasms; Case-Control Studies; Diet; Female; Genistein; Humans; Lignans; Middle Aged; Phytoestrogens; Plant Preparations; Premenopause; Risk Factors

2006
CYP17 genotype modifies the association between lignan supply and premenopausal breast cancer risk in humans.
    The Journal of nutrition, 2006, Volume: 136, Issue:6

    Topics: 4-Butyrolactone; Adult; Anticarcinogenic Agents; Breast Neoplasms; Case-Control Studies; Female; Genistein; Genotype; Germany; Humans; Lignans; Logistic Models; Middle Aged; Premenopause; Risk Factors; Steroid 17-alpha-Hydroxylase

2006
Flaxseed and its lignans inhibit estradiol-induced growth, angiogenesis, and secretion of vascular endothelial growth factor in human breast cancer xenografts in vivo.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2007, Feb-01, Volume: 13, Issue:3

    Topics: 4-Butyrolactone; Animals; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Endothelium, Vascular; Estradiol; Female; Flax; Humans; Lignans; Mice; Neoplasm Transplantation; Neovascularization, Pathologic; Phytoestrogens; Umbilical Veins; Vascular Endothelial Growth Factor A

2007
Estrogenic activity of 7-hydroxymatairesinol potassium acetate (HMR/lignan) from Norway spruce (Picea abies) knots and of its active metabolite enterolactone in MCF-7 cells.
    Pharmacological research, 2007, Volume: 56, Issue:2

    Topics: 4-Butyrolactone; Antioxidants; Apoptosis; bcl-2-Associated X Protein; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Estradiol; Estrogen Antagonists; Female; Gene Expression Regulation, Neoplastic; Humans; Lignans; Phytoestrogens; Picea; Proto-Oncogene Proteins c-bcl-2; RNA, Messenger; Tamoxifen

2007
Pharmacological blockade of fatty acid synthase (FASN) reverses acquired autoresistance to trastuzumab (Herceptin by transcriptionally inhibiting 'HER2 super-expression' occurring in high-dose trastuzumab-conditioned SKBR3/Tzb100 breast cancer cells.
    International journal of oncology, 2007, Volume: 31, Issue:4

    Topics: 4-Butyrolactone; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Apoptosis; Breast Neoplasms; Drug Resistance, Neoplasm; ErbB Receptors; Fatty Acid Synthase, Type I; Fatty Acid Synthases; Gene Expression Regulation, Neoplastic; Humans; Receptor, ErbB-2; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Transcription, Genetic; Trastuzumab; Tumor Cells, Cultured

2007
Fatty acid metabolism in breast cancer cells: differential inhibitory effects of epigallocatechin gallate (EGCG) and C75.
    Breast cancer research and treatment, 2008, Volume: 109, Issue:3

    Topics: 4-Butyrolactone; Apoptosis; Breast Neoplasms; Carnitine O-Palmitoyltransferase; Catechin; Enzyme Inhibitors; Fatty Acid Synthases; Fatty Acids; Female; Humans; Signal Transduction

2008
Global gene expression profiles induced by phytoestrogens in human breast cancer cells.
    Endocrine-related cancer, 2008, Volume: 15, Issue:1

    Topics: 4-Butyrolactone; Animals; Biomarkers, Tumor; Breast Neoplasms; Cattle; Estradiol; Estrogen Receptor beta; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Genistein; Humans; Isoflavones; Lignans; Milk; Neoplasm Proteins; Oligonucleotide Array Sequence Analysis; Phytoestrogens; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Soy Milk; Tumor Cells, Cultured

2008
Involvement of reactive oxygen species/c-Jun NH(2)-terminal kinase pathway in kotomolide A induces apoptosis in human breast cancer cells.
    Toxicology and applied pharmacology, 2008, Jun-01, Volume: 229, Issue:2

    Topics: 4-Butyrolactone; Animals; Apoptosis; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Enzyme Activation; Female; Humans; JNK Mitogen-Activated Protein Kinases; Mice; Mice, Inbred BALB C; Mice, Nude; Reactive Oxygen Species; Stereoisomerism

2008
Enterodiol and enterolactone, two major diet-derived polyphenol metabolites have different impact on ERalpha transcriptional activation in human breast cancer cells.
    The Journal of steroid biochemistry and molecular biology, 2008, Volume: 110, Issue:1-2

    Topics: 4-Butyrolactone; Animals; Blotting, Western; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; CHO Cells; Cricetinae; Cricetulus; Estrogen Receptor alpha; Flavonoids; HeLa Cells; Humans; Lignans; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Phenols; Phytoestrogens; Polyphenols; Reverse Transcriptase Polymerase Chain Reaction; Transcriptional Activation

2008
Excretion of the lignans enterolactone and enterodiol and of equol in omnivorous and vegetarian postmenopausal women and in women with breast cancer.
    Lancet (London, England), 1982, Dec-11, Volume: 2, Issue:8311

    Topics: 4-Butyrolactone; Aged; Benzopyrans; Breast Neoplasms; Butylene Glycols; Chromans; Diet; Diet, Vegetarian; Dietary Fiber; Energy Intake; Equol; Female; Furans; Humans; Isoflavones; Lignans; Menopause; Menstruation; Middle Aged; Plant Extracts

1982
Does fiber-rich food containing animal lignan precursors protect against both colon and breast cancer? An extension of the "fiber hypothesis".
    Gastroenterology, 1984, Volume: 86, Issue:4

    Topics: 4-Butyrolactone; Breast Neoplasms; Chemical Phenomena; Chemistry; Colonic Neoplasms; Dietary Fiber; Estrogens; Female; Humans; Lignans; Male; Plant Extracts

1984
Five novel mono-tetrahydrofuran ring acetogenins from the seeds of Annona muricata.
    Journal of natural products, 1996, Volume: 59, Issue:2

    Topics: 4-Butyrolactone; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Drug Screening Assays, Antitumor; HT29 Cells; Humans; Lung Neoplasms; Plant Tumors; Plants, Medicinal; Seeds; Tumor Cells, Cultured

1996
Squamotacin: an annonaceous acetogenin with cytotoxic selectivity for the human prostate tumor cell line (PC-3).
    Journal of natural products, 1996, Volume: 59, Issue:2

    Topics: 4-Butyrolactone; Animals; Antineoplastic Agents, Phytogenic; Artemia; Breast Neoplasms; Colonic Neoplasms; Humans; Kidney Neoplasms; Lung Neoplasms; Male; Pancreatic Neoplasms; Plants, Medicinal; Prostatic Neoplasms; Tumor Cells, Cultured

1996
Case-control study of phyto-oestrogens and breast cancer.
    Lancet (London, England), 1997, Oct-04, Volume: 350, Issue:9083

    Topics: 4-Butyrolactone; Breast Neoplasms; Case-Control Studies; Chromans; Diet; Equol; Estrogens, Non-Steroidal; Female; Humans; Isoflavones; Lignans; Middle Aged; Phytoestrogens; Plant Preparations; Plants; Risk Factors

1997
Effects of phytoestrogens on DNA synthesis in MCF-7 cells in the presence of estradiol or growth factors.
    Nutrition and cancer, 1998, Volume: 31, Issue:2

    Topics: 4-Butyrolactone; Anticarcinogenic Agents; Antineoplastic Agents, Hormonal; Breast Neoplasms; Chamomile; Coumestrol; DNA, Neoplasm; Epidermal Growth Factor; Estradiol; Estrogens, Non-Steroidal; Female; Flavonoids; Genistein; Humans; Insulin; Isoflavones; Lignans; Luteolin; Oils, Volatile; Phytoestrogens; Plant Preparations; Plants, Medicinal; Tamoxifen; Tumor Cells, Cultured

1998
Reliability of serum measurements of lignans and isoflavonoid phytoestrogens over a two-year period.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 1998, Volume: 7, Issue:10

    Topics: 4-Butyrolactone; Adult; Age Factors; Aged; Bias; Breast Neoplasms; Chromans; Equol; Feasibility Studies; Female; Genistein; Humans; Isoflavones; Lignans; Middle Aged; New York City; Pilot Projects; Postmenopause; Premenopause; Reference Values; Reproducibility of Results; Sensitivity and Specificity; Time Factors

1998
Circumvention of tumor multidrug resistance by a new annonaceous acetogenin: atemoyacin-B.
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1999, Volume: 20, Issue:5

    Topics: 4-Butyrolactone; Adenocarcinoma; Antineoplastic Agents, Phytogenic; Apoptosis; Breast Neoplasms; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Fatty Alcohols; Fura-2; Furans; Humans; KB Cells; Tumor Cells, Cultured

1999
Urinary phytoestrogens and postmenopausal breast cancer risk.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2001, Volume: 10, Issue:3

    Topics: 4-Butyrolactone; Aged; Biomarkers, Tumor; Breast Neoplasms; Case-Control Studies; Cohort Studies; Confidence Intervals; Estrogens, Non-Steroidal; Female; Fluoroimmunoassay; Genetic Predisposition to Disease; Genistein; Humans; Isoflavones; Lignans; Logistic Models; Mass Screening; Middle Aged; Netherlands; Odds Ratio; Phytoestrogens; Plant Preparations; Postmenopause; Predictive Value of Tests; Reference Values; Risk Assessment; Risk Factors; Sensitivity and Specificity

2001
Serum enterolactone and risk of breast cancer: a case-control study in eastern Finland.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2001, Volume: 10, Issue:4

    Topics: 4-Butyrolactone; Adult; Aged; Breast Neoplasms; Case-Control Studies; Diet; Dietary Fiber; Female; Finland; Humans; Lignans; Middle Aged; Odds Ratio; Plant Growth Regulators; Postmenopause; Premenopause; Preventive Medicine; Risk Factors; Vitamin E

2001
Enterolactone and estradiol inhibit each other's proliferative effect on MCF-7 breast cancer cells in culture.
    The Journal of steroid biochemistry and molecular biology, 1992, Volume: 41, Issue:3-8

    Topics: 4-Butyrolactone; Breast Neoplasms; Cell Division; Cell Line; DNA Replication; Estradiol; Estrogen Antagonists; Estrogens; Female; Humans; Kinetics; Lignans; Tumor Cells, Cultured

1992
Antiproliferative activity of mammalian lignan derivatives against the human breast carcinoma cell line, ZR-75-1.
    Cancer investigation, 1990, Volume: 8, Issue:6

    Topics: 4-Butyrolactone; Adenosine Triphosphatases; Animals; Benzyl Compounds; Breast Neoplasms; Butylene Glycols; Cell Division; Cell Line; Dogs; Dose-Response Relationship, Drug; Fluorouracil; Humans; Kidney Cortex; Lethal Dose 50; Lignans; Ouabain

1990
Stimulation of breast cancer cells in vitro by the environmental estrogen enterolactone and the phytoestrogen equol.
    Breast cancer research and treatment, 1987, Volume: 10, Issue:2

    Topics: 4-Butyrolactone; Benzopyrans; Breast Neoplasms; Butylene Glycols; Cell Division; Chromans; Equol; Estrogens; Female; Furans; Humans; Isoflavones; Lignans; Receptors, Progesterone; Tumor Cells, Cultured

1987