Page last updated: 2024-08-18

4-butyrolactone and Body Weight

4-butyrolactone has been researched along with Body Weight in 30 studies

Research

Studies (30)

Timeframe	Studies, this research(%)	All Research%
pre-1990	7 (23.33)	18.7374
1990's	4 (13.33)	18.2507
2000's	16 (53.33)	29.6817
2010's	3 (10.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Andreoli, R; Archetti, I; Biasiotto, G; Cadei, M; De Palma, G; Di Lorenzo, D; Luzzani, M; Monti, E; Mozzoni, P; Pacchetti, B; Predolini, F; Serana, F; Smeds, A; Zanella, I	1
Franke, AA; Hu, FB; Hu, Y; Song, Y; Sun, Q; van Dam, RM	1
Ariza, X; Asins, G; Bentebibel, A; Cordente, AG; García, J; Gómez-Puertas, P; Gurunathan, C; Hegardt, FG; Herrero, L; López-Viñas, E; Mera, P; Sebastián, D; Serra, D; Vázquez, I	1
Bommareddy, A; Chen, W; Dwivedi, C; Fahmy, H; Hildreth, MB; Kaushik, RS; Khalifa, S; Zeman, D; Zhang, X	1
Mathur, R	1
Benoit, SC; Clegg, DJ; McOsker, CC; Seeley, RJ; Wortman, MD	1
Bettler, B; Bräuner-Osborne, H; Cryan, JF; Froestl, W; Kaupmann, K; Klebs, K; Mombereau, C; Mosbacher, J; Sansig, G; Schmutz, M; van der Putten, H; Waldmeier, P; Wellendorph, P	1
Kim, EK; Kuhajda, FP; Moran, TH; Ronnett, GV; Thupari, JN	1
Cha, SH; Hu, Z; Lane, MD	1
Aja, S; Miller, I; Moran, TH; Ronnett, GV	1
Kim, EK; Kuhajda, FP; Moran, TH; Pinn, ML; Ronnett, GV; Thupari, JN; Tu, Y	1
Korte, H; Lina, B; Nyman, L; Unkila, M	1
Kim, EK; Landree, LE; Ronnett, GV; Tu, Y	1
Chen, JM; Power, KA; Saarinen, NM; Thompson, LU	1
Aja, S; Bi, S; Knipp, SB; Kuhajda, FP; McFadden, JM; Moran, TH; Ronnett, GV	1
Bügel, S; Ferrari, M; Hallund, J; Kjaer, A; Teerlink, T; Tetens, I; Tholstrup, T; Wiinberg, N	1
Aja, S; Aplasca, A; Daniels, K; Hyun, J; Kemm, M; Kleman, AM; Kuhajda, FP; Landree, LE; McFadden, JM; Medghalchi, SM; Moran, TH; Plummer, E; Ronnett, GV; Thupari, JN; Townsend, CA; Vadlamudi, A	1
Debeljuk, L; Díaz, MD; Maines, VM; Seilicovich, A	1
Burmeister, HR; Grove, MD; Kwolek, WF	1
Hara, A; Hirose, Y; Kawamori, T; Mori, H; Satoh, K; Tamai, Y; Tanaka, T; Torihara, M; Yamahara, J	1
Manchanda, SK; Mathur, R; Nayar, U; Oomura, Y	1
Kawabata, K; Matsunaga, K; Mori, H; Morishita, Y; Sugie, S; Tanaka, T; Yoshimi, N	1
Kumar, MV; Lane, MD; Shimokawa, T	1
Kumar, MV; Lane, MD; Nagy, TR; Shimokawa, T	1
Feron, VJ; Immel, HR; Kruysse, A; Til, HP	1
Aono, T; Azuma, K; Irahara, M; Kanematsu, T; Shitsukawa, K	1
Arvidsson, S; Holmberg, B; Kronevi, T	1
Oomura, Y; Plata-Salamán, CR; Shimizu, N	1
Hidaka, T; Hosoe, K; Watanabe, K; Yamashita, T	1
Scalzo, FM; Spear, LP	1

Reviews

1 review(s) available for 4-butyrolactone and Body Weight

Article	Year
Fatty acid metabolism as a target for obesity treatment. Physiology & behavior, 2005, May-19, Volume: 85, Issue:1 Topics: 4-Butyrolactone; Animals; Body Weight; Carnitine O-Palmitoyltransferase; Cerulenin; Eating; Energy Metabolism; Fatty Acid Synthases; Fatty Acids; Gene Expression; Humans; Models, Biological; Obesity	2005

Trials

1 trial(s) available for 4-butyrolactone and Body Weight

Article	Year
Daily consumption for six weeks of a lignan complex isolated from flaxseed does not affect endothelial function in healthy postmenopausal women. The Journal of nutrition, 2006, Volume: 136, Issue:9 Topics: 4-Butyrolactone; Aged; Arginine; Blood Pressure; Body Weight; Cross-Over Studies; Diet; Double-Blind Method; Endothelin-1; Endothelium, Vascular; Female; Flax; Humans; Lignans; Middle Aged; Nitrates; Nitrites; Nitroglycerin; Patient Compliance; Placebos; Postmenopause; Vasodilation	2006

Article

Year

Daily consumption for six weeks of a lignan complex isolated from flaxseed does not affect endothelial function in healthy postmenopausal women.

The Journal of nutrition, 2006, Volume: 136, Issue:9

Topics: 4-Butyrolactone; Aged; Arginine; Blood Pressure; Body Weight; Cross-Over Studies; Diet; Double-Blind Method; Endothelin-1; Endothelium, Vascular; Female; Flax; Humans; Lignans; Middle Aged; Nitrates; Nitrites; Nitroglycerin; Patient Compliance; Placebos; Postmenopause; Vasodilation

2006

Other Studies

28 other study(ies) available for 4-butyrolactone and Body Weight

Article	Year
7-Hydroxymatairesinol improves body weight, fat and sugar metabolism in C57BJ/6 mice on a high-fat diet. The British journal of nutrition, 2018, Volume: 120, Issue:7 Topics: 3T3-L1 Cells; 4-Butyrolactone; Adipogenesis; Adipose Tissue; Animals; Anti-Obesity Agents; Blood Glucose; Body Weight; Diet, High-Fat; Dietary Supplements; Fatty Liver; Gene Expression; Insulin Resistance; Lignans; Lipid Metabolism; Lipids; Male; Metabolic Syndrome; Mice; Mice, Inbred C57BL; Obesity; Picea; Plant Extracts	2018
A Prospective Investigation of the Association Between Urinary Excretion of Dietary Lignan Metabolites and Weight Change in US Women. American journal of epidemiology, 2015, Sep-15, Volume: 182, Issue:6 Topics: 4-Butyrolactone; Adult; Aged; Body Weight; Diabetes Mellitus, Type 2; Female; Follow-Up Studies; Humans; Incidence; Lignans; Middle Aged; Prospective Studies; United States; Urinalysis	2015
C75 is converted to C75-CoA in the hypothalamus, where it inhibits carnitine palmitoyltransferase 1 and decreases food intake and body weight. Biochemical pharmacology, 2009, Mar-15, Volume: 77, Issue:6 Topics: 4-Butyrolactone; Acyl Coenzyme A; Animals; Binding Sites; Body Weight; Carnitine O-Palmitoyltransferase; Eating; Female; Humans; Hypothalamus; Mice; Protein Structure, Secondary; Rats; Rats, Sprague-Dawley; Weight Loss	2009
Chemopreventive effects of sarcophine-diol on ultraviolet B-induced skin tumor development in SKH-1 hairless mice. Marine drugs, 2009, Apr-30, Volume: 7, Issue:2 Topics: 4-Butyrolactone; Animals; Antineoplastic Agents; Apoptosis; Body Weight; Carcinoma, Squamous Cell; Caspase 3; Caspase 8; DNA Fragmentation; Female; Gene Expression Regulation, Enzymologic; Mice; Mice, Hairless; Models, Animal; Neoplasms, Radiation-Induced; Skin Neoplasms; Ultraviolet Rays	2009
2-Buten-4-Olide (2-B4O) suppresses feeding in neonate and developing rat pups. Physiology & behavior, 2010, Sep-01, Volume: 101, Issue:2 Topics: 4-Butyrolactone; Age Factors; Animals; Animals, Newborn; Appetite Depressants; Body Weight; Dose-Response Relationship, Drug; Drug Administration Routes; Fasting; Feeding Behavior; Hypothalamus; Rats; Statistics, Nonparametric; Time Factors	2010
Comparison of central and peripheral administration of C75 on food intake, body weight, and conditioned taste aversion. Diabetes, 2002, Volume: 51, Issue:11 Topics: 4-Butyrolactone; Animals; Anorexia; Avoidance Learning; Body Weight; Cerebral Ventricles; Diet; Dose-Response Relationship, Drug; Energy Intake; Enzyme Inhibitors; Fatty Acid Synthases; Injections, Intraperitoneal; Injections, Intraventricular; Male; Mice; Rats; Rats, Long-Evans; Taste	2002
Specific gamma-hydroxybutyrate-binding sites but loss of pharmacological effects of gamma-hydroxybutyrate in GABA(B)(1)-deficient mice. The European journal of neuroscience, 2003, Volume: 18, Issue:10 Topics: 4-Butyrolactone; Adjuvants, Anesthesia; Animals; Anticonvulsants; Autoradiography; Baclofen; Behavior, Animal; Benzocycloheptenes; Binding, Competitive; Body Weight; Brain; Cell Membrane; Chromatography, High Pressure Liquid; Dihydroxyphenylalanine; Dose-Response Relationship, Drug; Drug Interactions; Electrochemistry; Electroencephalography; GABA-B Receptor Agonists; gamma-Aminobutyric Acid; Guanosine 5'-O-(3-Thiotriphosphate); Mice; Mice, Inbred BALB C; Mice, Knockout; Motor Activity; Organophosphorus Compounds; Phenols; Radioligand Assay; Receptors, GABA-B; Sodium Oxybate; Time Factors	2003
Chronic C75 treatment of diet-induced obese mice increases fat oxidation and reduces food intake to reduce adipose mass. American journal of physiology. Endocrinology and metabolism, 2004, Volume: 287, Issue:1 Topics: 4-Butyrolactone; Adipose Tissue; Animals; Body Weight; Carnitine O-Palmitoyltransferase; Chronic Disease; Diet; Eating; Fatty Acid Synthases; Fatty Acids; Fatty Liver; Male; Mice; Mice, Inbred C57BL; Obesity; Oxidation-Reduction; Treatment Outcome	2004
Long-term effects of a fatty acid synthase inhibitor on obese mice: food intake, hypothalamic neuropeptides, and UCP3. Biochemical and biophysical research communications, 2004, Apr-30, Volume: 317, Issue:2 Topics: 4-Butyrolactone; Adaptation, Physiological; Animals; Blood Glucose; Body Weight; Carrier Proteins; Dose-Response Relationship, Drug; Drinking; Drug Tolerance; Eating; Fatty Acid Synthases; Homeostasis; Hypothalamus; Ion Channels; Male; Mice; Mice, Inbred C57BL; Mitochondrial Proteins; Muscle, Skeletal; Neuropeptides; Obesity; Reference Values; Treatment Outcome; Uncoupling Protein 3	2004
Anorexigenic C75 alters c-Fos in mouse hypothalamic and hindbrain subnuclei. Neuroreport, 2004, Apr-09, Volume: 15, Issue:5 Topics: 4-Butyrolactone; Animals; Body Weight; Cell Count; Eating; Enzyme Inhibitors; Fasting; Hypothalamus; Immunohistochemistry; Male; Mice; Mice, Inbred BALB C; Proto-Oncogene Proteins c-fos; Rhombencephalon; Time Factors	2004
C75 alters central and peripheral gene expression to reduce food intake and increase energy expenditure. Endocrinology, 2005, Volume: 146, Issue:1 Topics: 4-Butyrolactone; Animals; Body Weight; Diet; Eating; Energy Metabolism; Fatty Acid Synthases; Fatty Acids; Gene Expression; Hypothalamus; Male; Mice; Mice, Inbred C57BL; Neuropeptides; Obesity; Oxidation-Reduction; Thinness	2005
A thirteen week dietary toxicity study with 7-hydroxymatairesinol potassium acetate (HMRlignan) in rats. Regulatory toxicology and pharmacology : RTP, 2005, Volume: 41, Issue:1 Topics: 4-Butyrolactone; Animals; Body Weight; Diet; Female; Lignans; Male; Motor Activity; No-Observed-Adverse-Effect Level; Organ Size; Potassium Acetate; Rats; Rats, Wistar	2005
Mammalian lignans enterolactone and enterodiol, alone and in combination with the isoflavone genistein, do not promote the growth of MCF-7 xenografts in ovariectomized athymic nude mice. International journal of cancer, 2006, Mar-01, Volume: 118, Issue:5 Topics: 4-Butyrolactone; Animals; Apoptosis; Body Weight; Cell Line, Tumor; Cell Proliferation; Drug Therapy, Combination; Feeding Behavior; Genistein; Humans; Lignans; Mice; Mice, Nude; Neoplasms; Ovariectomy; Xenograft Model Antitumor Assays	2006
Intracerebroventricular C75 decreases meal frequency and reduces AgRP gene expression in rats. American journal of physiology. Regulatory, integrative and comparative physiology, 2006, Volume: 291, Issue:1 Topics: 4-Butyrolactone; Agouti-Related Protein; Animals; Body Weight; Feeding Behavior; Gene Expression Regulation; Intercellular Signaling Peptides and Proteins; Male; Motor Activity; Peptide Hormones; Rats; Rats, Sprague-Dawley; RNA, Messenger	2006
Pharmacological stimulation of brain carnitine palmitoyl-transferase-1 decreases food intake and body weight. American journal of physiology. Regulatory, integrative and comparative physiology, 2008, Volume: 294, Issue:2 Topics: 4-Butyrolactone; Animals; Body Weight; Carnitine O-Palmitoyltransferase; Cell Line, Tumor; Dose-Response Relationship, Drug; Eating; Energy Metabolism; Enzyme Activation; Enzyme Inhibitors; Epoxy Compounds; Fatty Acid Synthesis Inhibitors; Fatty Acids; Female; Hypothalamus; Injections, Intraventricular; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Neurons; Pregnancy; Rats	2008
Prolonged treatment with gamma-aminobutyric acid (GABA)-mimetic substances in prepubertal male rats. Archives of andrology, 1983, Volume: 10, Issue:3 Topics: 4-Butyrolactone; Alkynes; Aminocaproates; Animals; Body Weight; gamma-Aminobutyric Acid; Male; Organ Size; Prolactin; Rats; Rats, Inbred Strains; Seminal Vesicles; Sexual Maturation; Testis; Time Factors	1983
Moniliformin and butenolide: effect on mice of high-level, long-term oral intake. Applied and environmental microbiology, 1980, Volume: 40, Issue:6 Topics: 4-Butyrolactone; Animals; Body Weight; Cyclobutanes; Furans; Fusarium; Lethal Dose 50; Mice; Mycotoxins	1980
Suppression of azoxymethane-induced colonic aberrant crypt foci by dietary exposure to a novel synthesized retinoidal butenolide, 5-hydroxy-4-(2-phenyl-(E)ethenyl)-2(5H)-furanone, in rats. Cancer letters, 1995, Jun-08, Volume: 92, Issue:2 Topics: 4-Butyrolactone; Animals; Anticarcinogenic Agents; Azoxymethane; Biogenic Polyamines; Biomarkers, Tumor; Body Weight; Cell Division; Colonic Neoplasms; Epithelium; Intestinal Mucosa; Liver; Male; Nucleolus Organizer Region; Organ Size; Ornithine Decarboxylase; Rats; Rats, Inbred F344; Retinoids; Silver Staining	1995
2-buten 4 olide affects feeding behavior of rhesus monkey. Progress in neuro-psychopharmacology & biological psychiatry, 1996, Volume: 20, Issue:1 Topics: 4-Butyrolactone; Animals; Behavior, Animal; Body Weight; Dose-Response Relationship, Drug; Feeding Behavior; Furans; Immunosuppressive Agents; Macaca mulatta; Male	1996
Regressive effects of various chemopreventive agents on azoxymethane-induced aberrant crypt foci in the rat colon. Japanese journal of cancer research : Gann, 1997, Volume: 88, Issue:9 Topics: 4-Butyrolactone; Animals; Anticarcinogenic Agents; Azoxymethane; Body Weight; Carcinogens; Chemoprevention; Chlorogenic Acid; Colonic Neoplasms; Drug Administration Schedule; Male; Methyl Methanesulfonate; Piroxicam; Rats; Rats, Inbred F344; Retinoids	1997
Effect of a fatty acid synthase inhibitor on food intake and expression of hypothalamic neuropeptides. Proceedings of the National Academy of Sciences of the United States of America, 2002, Jan-08, Volume: 99, Issue:1 Topics: 4-Butyrolactone; Animals; Blood Glucose; Body Weight; Cloning, Molecular; DNA, Complementary; Dose-Response Relationship, Drug; Down-Regulation; Enzyme Inhibitors; Fatty Acid Synthases; Food Deprivation; Hypothalamic Hormones; Hypothalamus; Insulin; Melanins; Mice; Mice, Inbred BALB C; Mice, Obese; Models, Biological; Nerve Tissue Proteins; Neuropeptides; Pituitary Hormones; Pro-Opiomelanocortin; Reverse Transcriptase Polymerase Chain Reaction; Ribonucleases; RNA, Messenger; Time Factors; Up-Regulation	2002
Differential effects of a centrally acting fatty acid synthase inhibitor in lean and obese mice. Proceedings of the National Academy of Sciences of the United States of America, 2002, Feb-19, Volume: 99, Issue:4 Topics: 4-Butyrolactone; Animals; Body Weight; Down-Regulation; Enzyme Inhibitors; Fatty Acid Synthases; Hypothalamus; Mice; Mice, Inbred C57BL; Mice, Obese; Obesity; Ribonucleases; RNA, Messenger; Time Factors; Up-Regulation	2002
Repeated exposure to butenolide vapour: subacute study in Syrian golden hamsters. Toxicology, 1979, Volume: 15, Issue:1 Topics: 4-Butyrolactone; Animals; Behavior, Animal; Body Weight; Cricetinae; Environmental Exposure; Female; Furans; Male; Mesocricetus; Nasal Mucosa; Smoking; Time Factors	1979
Effect of 2-buten-4-olide, an endogenous suppressant of feeding, on reproductive function in rats. Acta endocrinologica, 1990, Volume: 123, Issue:5 Topics: 4-Butyrolactone; Animals; Body Weight; Dose-Response Relationship, Drug; Estradiol; Estrus; Female; Furans; Gonadotropin-Releasing Hormone; Hypothalamus; Injections, Intraperitoneal; Luteinizing Hormone; Organ Size; Ovary; Pituitary Gland; Rats; Rats, Inbred Strains; Reproduction; Uterus	1990
Teratogenicity test of gamma-butyrolactone in the Sprague-Dawley rat. Pharmacology & toxicology, 1988, Volume: 62, Issue:1 Topics: 4-Butyrolactone; Abnormalities, Drug-Induced; Animals; Body Weight; Female; Furans; Growth; Pregnancy; Rats; Rats, Inbred Strains	1988
Endogenous sugar acid derivative acting as a feeding suppressant. Physiology & behavior, 1986, Volume: 38, Issue:3 Topics: 4-Butyrolactone; Animals; Body Weight; Drinking Behavior; Feeding Behavior; Furans; Injections, Intraperitoneal; Injections, Intraventricular; Intubation, Gastrointestinal; Male; Motor Activity; Rats; Rats, Inbred Strains	1986
Effect of alpha-(3,5-di-tert-butyl-4-hydroxybenzylidene)-gamma-butyrolactone (KME-4), a new anti-inflammatory drug, on the established adjuvant arthritis in rats. Japanese journal of pharmacology, 1986, Volume: 42, Issue:2 Topics: 4-Butyrolactone; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Arthritis, Experimental; Blood Proteins; Blood Sedimentation; Body Weight; Bone and Bones; Furans; Indomethacin; Male; Organ Size; Radiography; Rats; Rats, Inbred Strains	1986
Chronic haloperidol during development attenuates dopamine autoreceptor function in striatal and mesolimbic brain regions of young and older adult rats. Psychopharmacology, 1985, Volume: 85, Issue:3 Topics: 4-Butyrolactone; Aging; Animals; Body Weight; Corpus Striatum; Dopamine; Female; Haloperidol; Limbic System; Male; Nucleus Accumbens; Olfactory Bulb; Rats; Rats, Inbred Strains; Receptors, Dopamine; Sex Factors	1985