Compounds > 4-butyrolactone
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4-butyrolactone and Adjuvant Arthritis

4-butyrolactone has been researched along with Adjuvant Arthritis in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19902 (28.57)18.7374
1990's1 (14.29)18.2507
2000's2 (28.57)29.6817
2010's2 (28.57)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Beugnet, F; de Salazar Alcalá, AG; Dehman, A; Gioda, L1
Hsiao, HB; Hsieh, CC; Lin, H; Lin, WC; Wu, JB1
Aquino, M; Bruno, I; Guerrero, MD; Payá, M; Riccio, R; Terencio, MC1
Fujihara, H; Hashimoto, H; Kawasaki, M; Nakamura, T; Ohnishi, H; Okimoto, N; Onaka, T; Otsubo, H; Saito, J; Suzuki, H; Ueta, Y1
Alcaraz, MJ; De Giulio, A; De Rosa, S; García Pastor, P; Payá, M1
Fujimura, H; Hidaka, T; Hiramatsu, Y; Hosoe, K; Watanabe, K; Yamashita, T1
Hidaka, T; Hosoe, K; Watanabe, K; Yamashita, T1

Trials

1 trial(s) available for 4-butyrolactone and Adjuvant Arthritis

ArticleYear
Assessment of the efficacy of firocoxib (Previcox®) and grapiprant (Galliprant®) in an induced model of acute arthritis in dogs.
    BMC veterinary research, 2019, Aug-29, Volume: 15, Issue:1

    Topics: 4-Butyrolactone; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Dog Diseases; Dogs; Lameness, Animal; Random Allocation; Sulfones; Sulfonylurea Compounds; Uric Acid

2019

Other Studies

6 other study(ies) available for 4-butyrolactone and Adjuvant Arthritis

ArticleYear
Kinsenoside inhibits the inflammatory mediator release in a type-II collagen induced arthritis mouse model by regulating the T cells responses.
    BMC complementary and alternative medicine, 2016, Feb-25, Volume: 16

    Topics: 4-Butyrolactone; Animals; Anti-Inflammatory Agents; Antirheumatic Agents; Arthritis, Experimental; Arthritis, Rheumatoid; Collagen Type II; Cytokines; Disease Models, Animal; Edema; Inflammation Mediators; Knee Joint; Male; Mice, Inbred DBA; Monosaccharides; Orchidaceae; Phytotherapy; Plant Extracts; T-Lymphocytes

2016
Anti-inflammatory and analgesic activity of a novel inhibitor of microsomal prostaglandin E synthase-1 expression.
    European journal of pharmacology, 2009, Oct-12, Volume: 620, Issue:1-3

    Topics: 4-Butyrolactone; Acetates; Analgesics; Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Behavior, Animal; Blood Platelets; Cattle; Chronic Disease; Gene Expression Regulation, Enzymologic; Humans; Hyperalgesia; Inflammation; Intramolecular Oxidoreductases; Leukotriene B4; Male; Mice; Neutrophils; Prostaglandin-E Synthases; Thiophenes; Thromboxane B2

2009
Effects of the short chain sugar acid 2-buten-4-olide on the hypothalamo-pituitary-adrenal axis in normal and adjuvant-induced arthritic rats.
    Journal of neuroendocrinology, 2007, Volume: 19, Issue:1

    Topics: 4-Butyrolactone; Adjuvants, Immunologic; Animals; Appetite Depressants; Arginine Vasopressin; Arthritis, Experimental; Corticosterone; Corticotropin-Releasing Hormone; Hypothalamo-Hypophyseal System; Injections, Intraperitoneal; Male; Pituitary-Adrenal System; Proto-Oncogene Proteins c-fos; Rats; Rats, Inbred Lew

2007
Modulation of acute and chronic inflammatory processes by cacospongionolide B, a novel inhibitor of human synovial phospholipase A2.
    British journal of pharmacology, 1999, Volume: 126, Issue:1

    Topics: 4-Butyrolactone; Acute Disease; Animals; Anti-Infective Agents; Arthritis, Experimental; Chronic Disease; Dose-Response Relationship, Drug; Ear; Edema; Enzymes; Female; Humans; Inflammation; Leukocytes; Male; Mice; Phospholipases A; Phospholipases A2; Pyrans; Rats; Rats, Wistar; Synovial Fluid; U937 Cells

1999
Analgesic and anti-inflammatory activities in rats of alpha-(3,5-di-t-butyl-4-hydroxybenzylidene)-gamma-butyrolactone (KME-4), and its intestinal damage.
    The Journal of pharmacy and pharmacology, 1986, Volume: 38, Issue:10

    Topics: 4-Butyrolactone; Acetates; Acetic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Capillary Permeability; Edema; Furans; Ibuprofen; Indomethacin; Intestinal Diseases; Lethal Dose 50; Male; Naproxen; Rats; Rats, Inbred Strains

1986
Effect of alpha-(3,5-di-tert-butyl-4-hydroxybenzylidene)-gamma-butyrolactone (KME-4), a new anti-inflammatory drug, on the established adjuvant arthritis in rats.
    Japanese journal of pharmacology, 1986, Volume: 42, Issue:2

    Topics: 4-Butyrolactone; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Arthritis, Experimental; Blood Proteins; Blood Sedimentation; Body Weight; Bone and Bones; Furans; Indomethacin; Male; Organ Size; Radiography; Rats; Rats, Inbred Strains

1986