Compounds > 4-boronophenylalanine
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4-boronophenylalanine and Melanoma

4-boronophenylalanine has been researched along with Melanoma in 31 studies

Research

Studies (31)

TimeframeStudies, this research(%)All Research%
pre-19903 (9.68)18.7374
1990's14 (45.16)18.2507
2000's7 (22.58)29.6817
2010's3 (9.68)24.3611
2020's4 (12.90)2.80

Authors

AuthorsStudies
Fukuda, H1
Abe, Y; Fujii, R; Igaki, H; Imahori, Y; Itami, J; Kurihara, H; Morita, T; Nakamura, M; Nakamura, S; Nakayama, Y; Nishioka, S; Okamoto, H1
Date, H; Fukunaga, H; Matsuya, Y; Omura, M1
Fukuda, H; Hiratsuka, J1
Barth, RF; Chandra, S; Haider, SA; Huo, T; Kabalka, GW; Shaikh, AL; Yang, W1
Casal, M; Dagrosa, MA; Juvenal, GJ; Navarro, A; Pisarev, MA; Portu, A; Rossini, AE; Saint Martin, G; Thorp, S1
Barth, RF1
Blaumann, H; Calzetta Larrieu, OA; Casal, MR; Feld, DB; Fernández, C; González, SJ; Jiménez Rebagliati, R; Kessler, J; Liberman, SJ; Longhino, J; Menéndez, PR; Nievas, SI; Pereira, MD; Roth, BM; Santa Cruz, GA1
Arnopolskaya, AM; Khokhlov, VF; Kozlovskaya, NG; Kulakov, VN; Mitin, VN; Portnov, AA; Sheino, IN; Zaitsev, KN1
Ichihashi, M; Mishima, Y; Tsuji, M1
Ichihashi, M; Mishima, Y; Nakanishi, T1
Honda, C; Ichihashi, M; Mishima, Y; Wadabayashi, N1
Feinendegen, LE; Müller-Gärtner, HW; Papaspyrou, M1
Fukuda, H; Ichihashi, M; Mishima, Y1
Bailey, MQ; Barth, RF; Coderre, JA; Matalka, KZ; Moeschberger, ML; Rofstad, EK; Soloway, AH; Staubus, AE2
Allen, BJ; Jones, R; Mallesch, JL; McCarthy, WH; Moore, DE; Stening, WA1
Abe, Y; Fukuda, H; Hiratsuka, J; Honda, C; Ichihashi, M; Kanda, K; Karashima, H; Kobayashi, T; Takahashi, J; Yoshino, K1
Carlsson, J; Lindström, P; Olsson, P; Pettersson, OA; Sjöberg, S1
Bartelink, H; Begg, AC; Gregoire, V; Huiskamp, R; Verrijk, R1
Ichihashi, M; Kobayashi, T; Mizuma, N; Tano, K; Utsumi, H1
Abe, Y; Akaizawa, T; Fukuda, H; Hiratsuka, J; Honda, C; Ichihashi, M; Kobayashi, T; Mishima, Y; Takahashi, J; Wadabayashi, N; Yoshino, K1
Bendel, P; Kabalka, GW; Panov, V; Salomon, Y1
Kondoh, H; Mishima, Y1
Busse, PM; Kiger, WS; Palmer, MR; Riley, KJ; Zamenhof, RG1
Cassapo, R; Castro, M; Chaveca, T; Fernandes, AP; Gonçalves, IC; Oliveira, NG; Rodrigues, AS; Rueff, J; Toscano-Rico, JM1
Barth, RF; Bartus, RT; Coderre, JA; Ferketich, AK; Moeschberger, ML; Nawrocky, MM; Rofstad, EK; Rotaru, JH; Yang, W1
Mishima, Y1
Hatta, S; Honda, C; Ichihashi, M; Mishima, Y1
Barth, RF; Fairchild, RG; Soloway, AH1
Coderre, JA; Cohen, S; Fairchild, RG; Fand, I; Glass, JD; Roy, U1

Reviews

3 review(s) available for 4-boronophenylalanine and Melanoma

ArticleYear
Boron Neutron Capture Therapy (BNCT) for Cutaneous Malignant Melanoma Using
    Cells, 2021, 10-26, Volume: 10, Issue:11

    Topics: Boron Compounds; Boron Neutron Capture Therapy; Clinical Trials as Topic; Humans; Melanoma; Melanoma, Cutaneous Malignant; Phenylalanine; Radiobiology; Relative Biological Effectiveness; Skin Neoplasms

2021
Pharmacokinetics of
    Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 2020, Volume: 166

    Topics: Boron; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Glioblastoma; Humans; Isotopes; Melanoma; Neoplasms; Phenylalanine; Positron-Emission Tomography

2020
A post melanosomal era: control of melanogenesis and melanoma growth.
    Pigment cell research, 1992, Volume: Suppl 2

    Topics: Adolescent; Animals; Boron; Boron Compounds; Cricetinae; Fatty Acids, Unsaturated; Gene Expression Regulation, Neoplastic; Hair Color; Humans; Infant, Newborn; Isotopes; Male; Melanins; Melanocytes; Melanoma; Melanoma, Experimental; Models, Biological; Monophenol Monooxygenase; Neoplasm Proteins; Neutrons; Phenylalanine; Pigmentation Disorders; Protein Processing, Post-Translational; Pyrones; Radiation-Sensitizing Agents; Skin Pigmentation; Subcellular Fractions; Swine

1992

Trials

3 trial(s) available for 4-boronophenylalanine and Melanoma

ArticleYear
BNCT for skin melanoma in extremities: updated Argentine clinical results.
    Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 2009, Volume: 67, Issue:7-8 Suppl

    Topics: Aged; Argentina; Boron Compounds; Boron Neutron Capture Therapy; Female; Humans; Leg; Male; Melanoma; Middle Aged; Phenylalanine; Radiation-Sensitizing Agents; Radiotherapy Dosage; Radiotherapy Planning, Computer-Assisted; Skin Neoplasms

2009
Boron neutron capture therapy of malignant melanoma using 10B-paraboronophenylalanine with special reference to evaluation of radiation dose and damage to the normal skin.
    Radiation research, 1994, Volume: 138, Issue:3

    Topics: Aged; Boron Compounds; Boron Neutron Capture Therapy; Female; Humans; Male; Melanoma; Middle Aged; Phenylalanine; Radiation-Sensitizing Agents; Radiotherapy Dosage; Skin; Skin Neoplasms

1994
A pharmacokinetic model for the concentration of 10B in blood after boronophenylalanine-fructose administration in humans.
    Radiation research, 2001, Volume: 155, Issue:4

    Topics: Adult; Aged; Boron; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Female; Fructose; Glioblastoma; Humans; Infusions, Intravenous; Male; Melanoma; Middle Aged; Models, Biological; Phenylalanine; Skin Neoplasms

2001

Other Studies

25 other study(ies) available for 4-boronophenylalanine and Melanoma

ArticleYear
Comparison of
    Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 2020, Volume: 157

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Boron Compounds; Child; Female; Fluorodeoxyglucose F18; Humans; Male; Melanoma; Middle Aged; Phenylalanine; Positron-Emission Tomography; Young Adult

2020
A Model for Estimating Dose-Rate Effects on Cell-Killing of Human Melanoma after Boron Neutron Capture Therapy.
    Cells, 2020, 04-30, Volume: 9, Issue:5

    Topics: Boron; Boron Compounds; Boron Neutron Capture Therapy; Cell Death; Cell Line, Tumor; Cell Survival; Cobalt Radioisotopes; Computer Simulation; Dose-Response Relationship, Radiation; Gamma Rays; Humans; Isotopes; Melanoma; Models, Biological; Monte Carlo Method; Neutrons; Phenylalanine; Radiometry; Relative Biological Effectiveness; Time Factors

2020
Effects of l-DOPA pre-loading on the uptake of boronophenylalanine using the F98 glioma and B16 melanoma models.
    Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 2014, Volume: 88

    Topics: Animals; Boron Compounds; Brain Neoplasms; Drug Synergism; Female; Glioma; Levodopa; Melanoma; Metabolic Clearance Rate; Mice; Mice, Inbred C57BL; Organ Specificity; Phenylalanine; Premedication; Tissue Distribution; Treatment Outcome

2014
Assessment of biological effectiveness of boron neutron capture therapy in primary and metastatic melanoma cell lines.
    International journal of radiation biology, 2015, Volume: 91, Issue:1

    Topics: Autoradiography; Biological Transport; Boron Compounds; Boron Neutron Capture Therapy; Cell Line, Tumor; Humans; Intracellular Space; Melanoma; Neoplasm Metastasis; Phenylalanine; Radiation Tolerance; Relative Biological Effectiveness

2015
From the laboratory to the clinic: How translational studies in animals have lead to clinical advances in boron neutron capture therapy.
    Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 2015, Volume: 106

    Topics: Animals; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Melanoma; Phenylalanine; Translational Research, Biomedical

2015
Comparison of BNCT and GdNCT efficacy in treatment of canine cancer.
    Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 2009, Volume: 67, Issue:7-8 Suppl

    Topics: Animals; Bone Neoplasms; Boron Compounds; Boron Neutron Capture Therapy; Combined Modality Therapy; Dog Diseases; Dogs; Gadolinium; Humans; Melanoma; Mouth Neoplasms; Neoplasms; Neutron Capture Therapy; Osteosarcoma; Phenylalanine

2009
[Selective affinity of 10B1-paraboronophenylalanine-HCl to malignant melanoma: thermal neutron capture therapy].
    Nihon Hifuka Gakkai zasshi. The Japanese journal of dermatology, 1983, Volume: 93, Issue:7

    Topics: Animals; Boron; Boron Compounds; Cricetinae; Isotopes; Melanoma; Neoplasms, Experimental; Neutrons; Phenylalanine; Skin; Skin Neoplasms; Spectrometry, Gamma

1983
Specific killing effect of 10B1-para-boronophenylalanine in thermal neutron capture therapy of malignant melanoma: in vitro radiobiological evaluation.
    The Journal of investigative dermatology, 1982, Volume: 78, Issue:3

    Topics: Boron Compounds; Cell Survival; Cells, Cultured; Culture Media; Humans; In Vitro Techniques; Melanoma; Neutrons; Phenylalanine; Premedication; Radiation-Sensitizing Agents; Skin Neoplasms

1982
Selective boron accumulation in human ocular melanoma vs surrounding eye components after 10B1-p-boronophenylalanine administration. Prerequisite for clinical trial of neutron-capture therapy.
    Melanoma research, 1994, Volume: 4, Issue:3

    Topics: Boron; Boron Compounds; Clinical Trials as Topic; Eye Neoplasms; Humans; Isotopes; Mass Spectrometry; Melanoma; Neutron Capture Therapy; Phenylalanine; Radiation-Sensitizing Agents

1994
Preloading with L-tyrosine increases the uptake of boronophenylalanine in mouse melanoma cells.
    Cancer research, 1994, Dec-15, Volume: 54, Issue:24

    Topics: Animals; Boron; Boron Compounds; Boron Neutron Capture Therapy; Melanoma; Mice; Phenylalanine; Radiation-Sensitizing Agents; Time Factors; Tumor Cells, Cultured; Tyrosine

1994
[Neutron capture therapy for cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1994, Volume: 21, Issue:3

    Topics: Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Humans; Infusions, Intravenous; Melanoma; Phenylalanine; Skin Neoplasms

1994
A nude rat model for neutron capture therapy of human intracerebral melanoma.
    International journal of radiation oncology, biology, physics, 1994, Mar-30, Volume: 28, Issue:5

    Topics: Animals; Boron Compounds; Boron Neutron Capture Therapy; Brain; Brain Neoplasms; Female; Humans; Male; Melanoma; Mice; Middle Aged; Neoplasm Transplantation; Phenylalanine; Rats; Rats, Nude; Tumor Cells, Cultured

1994
The pharmacokinetics of p-Boronophenylalanine.fructose in human patients with glioma and metastatic melanoma.
    International journal of radiation oncology, biology, physics, 1994, Mar-30, Volume: 28, Issue:5

    Topics: Boron; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Glioma; Humans; Melanoma; Phenylalanine; Radiation-Sensitizing Agents

1994
Penetration and binding of L- and D-carboranylalanine in human melanoma spheroids.
    Melanoma research, 1993, Volume: 3, Issue:5

    Topics: Boron Compounds; Boron Neutron Capture Therapy; Cell Aggregation; Cell Cycle; Humans; Melanoma; Phenylalanine; Radiation-Sensitizing Agents; Stereoisomerism; Thymidine; Tritium; Tumor Cells, Cultured

1993
Boron neutron capture therapy of intracerebral melanoma using boronophenylalanine as a capture agent.
    Cancer research, 1993, Jul-15, Volume: 53, Issue:14

    Topics: Animals; Boron; Boron Compounds; Boron Neutron Capture Therapy; Brain; Brain Neoplasms; Cell Survival; Humans; Male; Melanoma; Middle Aged; Phenylalanine; Radiation-Sensitizing Agents; Radiotherapy Dosage; Rats; Rats, Nude; Tissue Distribution

1993
Selectivity of boron carriers for boron neutron capture therapy: pharmacological studies with borocaptate sodium, L-boronophenylalanine and boric acid in murine tumors.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 1993, Volume: 27, Issue:1

    Topics: Animals; Boric Acids; Borohydrides; Boron Compounds; Boron Neutron Capture Therapy; Brain; Dose-Response Relationship, Drug; Female; Half-Life; Injections, Intraperitoneal; Kidney; Liver; Male; Melanoma; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Inbred Strains; Phenylalanine; Radiation-Sensitizing Agents; Sarcoma, Experimental; Sulfhydryl Compounds; Time Factors

1993
Cellular effect of thermal neutron capture treatment using 10B1-para-boronophenylalanine: lethal effect on melanoma cells with different degrees of X-ray sensitivity.
    Journal of radiation research, 1996, Volume: 37, Issue:3

    Topics: Antibiotics, Antineoplastic; Bleomycin; Boron Compounds; Boron Neutron Capture Therapy; Humans; Melanoma; Phenylalanine; Radiation Tolerance; Radiation-Sensitizing Agents; Tumor Cells, Cultured

1996
Pharmacokinetics of 10B-p-boronophenylalanine in tumours, skin and blood of melanoma patients: a study of boron neutron capture therapy for malignant melanoma.
    Melanoma research, 1999, Volume: 9, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Boron Compounds; Boron Neutron Capture Therapy; Female; Humans; Male; Melanoma; Middle Aged; Phenylalanine; Skin; Skin Neoplasms; Time Factors

1999
Uptake and washout of borocaptate sodium and borono-phenylalanine in cultured melanoma cells: a multi-nuclear NMR study.
    Radiation research, 2000, Volume: 154, Issue:1

    Topics: Animals; Biological Transport; Borohydrides; Boron Compounds; Culture Media; Melanoma; Mice; Nuclear Magnetic Resonance, Biomolecular; Perfusion; Phenylalanine; Radiation-Sensitizing Agents; Signal Transduction; Sulfhydryl Compounds; Tumor Cells, Cultured

2000
Dual control of melanogenesis and melanoma growth: overview molecular to clinical level and the reverse.
    Pigment cell research, 2000, Volume: 13 Suppl 8

    Topics: Animals; Boron Compounds; Humans; Indolequinones; Indoles; Melanins; Melanoma; Melanosis; Phenylalanine; Quinones; Skin Pigmentation; Subcellular Fractions

2000
Evaluation of the genotoxic effects of the boron neutron capture reaction in human melanoma cells using the cytokinesis block micronucleus assay.
    Mutagenesis, 2001, Volume: 16, Issue:5

    Topics: Animals; Boron; Boron Compounds; Boron Neutron Capture Therapy; Cell Division; Cell Line; Cells, Cultured; Cricetinae; Drug Carriers; Fast Neutrons; Humans; Isotopes; Melanoma; Micronucleus Tests; Phenylalanine; Radiation-Sensitizing Agents; Tumor Cells, Cultured

2001
Neutron capture therapy of intracerebral melanoma: enhanced survival and cure after blood-brain barrier opening to improve delivery of boronophenylalanine.
    International journal of radiation oncology, biology, physics, 2002, Mar-01, Volume: 52, Issue:3

    Topics: Animals; Blood-Brain Barrier; Boron Compounds; Boron Neutron Capture Therapy; Bradykinin; Brain Neoplasms; Humans; Mannitol; Melanoma; Osmosis; Phenylalanine; Radiation-Sensitizing Agents; Rats; Rats, Nude

2002
In situ detection of cutaneous melanoma by prompt gamma-ray spectrometry using melanoma-seeking 10B-dopa analogue.
    Journal of dermatological science, 1990, Volume: 1, Issue:1

    Topics: Aged; Animals; Boron; Boron Compounds; Cricetinae; Disease Models, Animal; Female; Humans; Isotopes; Male; Melanoma; Mesocricetus; Phenylalanine; Skin Neoplasms; Spectrometry, Gamma; Time Factors

1990
Boron neutron capture therapy for cancer.
    Scientific American, 1990, Volume: 263, Issue:4

    Topics: Alpha Particles; Animals; Antibodies, Monoclonal; Boron; Boron Compounds; Brain Neoplasms; Glioblastoma; Humans; Immunotoxins; Isotopes; Melanoma; Mice; Neoplasms; Neutrons; Phenylalanine; Radiation Dosage

1990
Selective targeting of boronophenylalanine to melanoma in BALB/c mice for neutron capture therapy.
    Cancer research, 1987, Dec-01, Volume: 47, Issue:23

    Topics: Animals; Boron Compounds; Mammary Neoplasms, Experimental; Melanins; Melanoma; Mice; Mice, Inbred BALB C; Neutrons; Phenylalanine; Stereoisomerism; Tissue Distribution

1987