Page last updated: 2024-08-23

4-boronophenylalanine and Glioma

4-boronophenylalanine has been researched along with Glioma in 26 studies

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's14 (53.85)18.2507
2000's9 (34.62)29.6817
2010's2 (7.69)24.3611
2020's1 (3.85)2.80

Authors

AuthorsStudies
Adams, DM; Barth, RF; Cai, J; Hariharan, JR; Radcliffe, K; Soloway, AH; Wyzlic, IM1
Azab, AK; Confalonieri, L; Del Grosso, E; Fallarini, S; Imperio, D; Muz, B; Panza, L1
Barth, RF; Chandra, S; Haider, SA; Huo, T; Kabalka, GW; Shaikh, AL; Yang, W1
Chang, CW; Chang, WY; Chen, JC; Li, JJ; Wang, HE; Yang, FY1
Bozzali, M; Cametti, C; Capuani, S; D'Amore, E; Gili, T; Lazzarino, G; Maraviglia, B; Muolo, M; Pastore, FS; Porcari, P; Russo, S1
Boddy, A; Braithwaite, R; Chester, M; Chopra, A; Croswell, G; Cruickshank, GS; Detta, A; Doran, J; Elliot, M; Ford, S; Ghani, Z; Graham, N; Green, S; Halbert, G; Hardie, J; James, ND; Lockyer, N; Ngoga, D; Sheehan, TM; Steinfeldt, H; Sugar, R; Vickerman, J; Wojnecki, C1
Barth, RF1
Barth, RF; Binns, P; Riley, K; Tjarks, W; Wu, G; Yang, W1
Al-Madhoun, AS; Barth, RF; Byun, Y; Chandra, S; Eriksson, S; Johnsamuel, J; Smith, DR; Tjarks, W; Yang, W1
Betti, M; Carlos, R; Cionini, L; de las Heras, LA; Lazzerini, G; Menichetti, L; Pitois, A; Salvatori, PA; Zampolli, A1
Asano, T; Hattori, Y; Kirihata, M; Kondoh, H; Kurihara, K; Wakamiya, T; Yamaguchi, Y1
Allen, BJ; Jones, R; Mallesch, JL; McCarthy, WH; Moore, DE; Stening, WA1
Barth, RF; Coderre, JA; Matalka, KZ; Moeschberger, ML; Staubus, AE1
Cai, J; Iwamoto, S; Kikuchi, H; Nemoto, H; Oda, Y; Ono, K; Takagaki, M; Yamamoto, Y1
Barth, RF; Carpenter, DE; Goodman, JH; Moeschberger, ML; Yang, W1
Barth, RF; Goodman, JH; Joel, DD; Moeschberger, ML; Nawrocky, MM; Rotaru, JH; Soloway, AH; Yang, W1
Barth, RF; Goodman, JH; Joel, DD; Moeschberger, ML; Nawrocky, MM; Rotaru, JH; Yang, W1
Fujii, R; Ido, T; Imahori, Y; Kusuki, T; Ohmori, Y; Ono, K; Ueda, S1
Fujii, R; Ido, T; Imahori, Y; Kobayashi, T; Kusuki, T; Ohmori, Y; Ono, K; Sakae, K; Takagaki, M; Ueda, S2
Barth, RF; Bartus, RT; Goodman, JH; Moeschberger, ML; Yang, W1
Barth, RF; Boesel, CP; Goodman, JH; Joel, DD; Moeschberger, ML; Nawrocky, MM; Ono, K; Rotaru, JH; Soloway, AH; Yang, W1
Barth, RF; Bartus, RT; Coderre, JA; Ferketich, AK; Goodman, JH; Moeschberger, ML; Nawrocky, MM; Rotaru, JH; Yang, W1
Adelman, LS; Cano, G; Harling, OK; Joyce, MA; Kerley, SE; Madoc-Jones, H; Saris, SC; Solares, GR; Wazer, DE; Zamenhof, RG1
Coderre, JA; Joel, DD; Micca, PL; Nawrocky, MM; Slatkin, DN1
Coderre, JA; Fairchild, RG; Fand, I; Glass, JD; Joel, DD; Micca, PL1

Reviews

1 review(s) available for 4-boronophenylalanine and Glioma

ArticleYear
Boron neutron capture therapy at the crossroads: challenges and opportunities.
    Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 2009, Volume: 67, Issue:7-8 Suppl

    Topics: Animals; Borohydrides; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Fast Neutrons; Glioma; Humans; Nuclear Reactors; Phenylalanine; Radiation-Sensitizing Agents; Radiotherapy Planning, Computer-Assisted; Randomized Controlled Trials as Topic; Rats; Sulfhydryl Compounds

2009

Trials

1 trial(s) available for 4-boronophenylalanine and Glioma

ArticleYear
A cancer research UK pharmacokinetic study of BPA-mannitol in patients with high grade glioma to optimise uptake parameters for clinical trials of BNCT.
    Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 2009, Volume: 67, Issue:7-8 Suppl

    Topics: Aged; Blood-Brain Barrier; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Glioma; Humans; Male; Mannitol; Phenylalanine; Radiation-Sensitizing Agents; United Kingdom

2009

Other Studies

24 other study(ies) available for 4-boronophenylalanine and Glioma

ArticleYear
Boron-containing polyamines as DNA targeting agents for neutron capture therapy of brain tumors: synthesis and biological evaluation.
    Journal of medicinal chemistry, 1997, Nov-21, Volume: 40, Issue:24

    Topics: Animals; Antineoplastic Agents; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; DNA; Female; Glioma; Pregnancy; Rats; Rats, Inbred F344; Spermidine; Spermine; Structure-Activity Relationship; Tumor Cells, Cultured

1997
Synthesis, equilibrium, and biological study of a C-7 glucose boronic acid derivative as a potential candidate for boron neutron capture therapy.
    Bioorganic & medicinal chemistry, 2022, 04-01, Volume: 59

    Topics: Boron; Boron Compounds; Boron Neutron Capture Therapy; Boronic Acids; Carbohydrates; Cell Line, Tumor; Glioma; Glucose; Humans

2022
Effects of l-DOPA pre-loading on the uptake of boronophenylalanine using the F98 glioma and B16 melanoma models.
    Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 2014, Volume: 88

    Topics: Animals; Boron Compounds; Brain Neoplasms; Drug Synergism; Female; Glioma; Levodopa; Melanoma; Metabolic Clearance Rate; Mice; Mice, Inbred C57BL; Organ Specificity; Phenylalanine; Premedication; Tissue Distribution; Treatment Outcome

2014
Pharmacokinetic analysis and uptake of 18F-FBPA-Fr after ultrasound-induced blood-brain barrier disruption for potential enhancement of boron delivery for neutron capture therapy.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2014, Volume: 55, Issue:4

    Topics: Animals; Apoptosis; Blood-Brain Barrier; Boron Compounds; Brain Neoplasms; Drug Delivery Systems; Glioma; Glycopeptides; In Situ Nick-End Labeling; Male; Neoplasm Transplantation; Neutron Capture Therapy; Phenylalanine; Positron-Emission Tomography; Radiopharmaceuticals; Rats; Rats, Inbred F344; Ultrasonics

2014
Boronophenylalanine uptake in C6 glioma model is dramatically increased by L-DOPA preloading.
    Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 2009, Volume: 67, Issue:7-8 Suppl

    Topics: Animals; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Cell Line, Tumor; Glioma; In Vitro Techniques; Levodopa; Magnetic Resonance Imaging; Male; Phenylalanine; Radiation-Sensitizing Agents; Rats; Rats, Wistar

2009
Boron neutron capture therapy of EGFR or EGFRvIII positive gliomas using either boronated monoclonal antibodies or epidermal growth factor as molecular targeting agents.
    Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 2009, Volume: 67, Issue:7-8 Suppl

    Topics: Animals; Antibodies, Monoclonal; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Cell Line, Tumor; ErbB Receptors; Glioma; Head and Neck Neoplasms; Humans; Phenylalanine; Radiation-Sensitizing Agents; Radiometry; Rats; Rats, Inbred F344

2009
Boron-containing nucleosides as potential delivery agents for neutron capture therapy of brain tumors.
    Cancer research, 2004, Sep-01, Volume: 64, Issue:17

    Topics: Animals; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Cell Division; Glioma; Humans; Male; Mice; Mice, Inbred C3H; Mice, Nude; Middle Aged; Phenylalanine; Phosphorylation; Rats; Rats, Inbred F344; Spectrometry, Mass, Secondary Ion; Subcellular Fractions; Thymidine; Thymidine Kinase

2004
Capillary electrophoresis-electrospray mass spectrometry and HR-ICP-MS for the detection and quantification of 10B-boronophenylalanine (10B-BPA) used in boron neutron capture therapy.
    Analytical and bioanalytical chemistry, 2006, Volume: 384, Issue:3

    Topics: Animals; Boron Compounds; Boron Neutron Capture Therapy; Cell Line, Tumor; Electrophoresis, Capillary; Endothelial Cells; Glioma; Humans; Isotopes; Mass Spectrometry; Molecular Structure; Phenylalanine; Rats; Sensitivity and Specificity; Time Factors

2006
Biological evaluation of fluorinated p-boronophenylalanine derivatives as a boron carrier.
    Protein and peptide letters, 2007, Volume: 14, Issue:3

    Topics: Animals; Antineoplastic Agents; Boron; Boron Compounds; Cell Survival; Drug Evaluation, Preclinical; Drug Screening Assays, Antitumor; Glioma; Hydrocarbons, Fluorinated; Ion Transport; Models, Biological; Phenylalanine; Rats; Solubility; Tumor Cells, Cultured

2007
The pharmacokinetics of p-Boronophenylalanine.fructose in human patients with glioma and metastatic melanoma.
    International journal of radiation oncology, biology, physics, 1994, Mar-30, Volume: 28, Issue:5

    Topics: Boron; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Glioma; Humans; Melanoma; Phenylalanine; Radiation-Sensitizing Agents

1994
Neutron capture therapy of a rat glioma using boronophenylalanine as a capture agent.
    Radiation research, 1994, Volume: 137, Issue:1

    Topics: Animals; Boron Compounds; Brain; Cell Survival; Dose-Response Relationship, Radiation; Glioma; Male; Neutron Capture Therapy; Phenylalanine; Radiation-Sensitizing Agents; Rats; Rats, Inbred F344; Survival Analysis; Time Factors; Tissue Distribution; Tumor Cells, Cultured; X-Rays

1994
Hydroxylforms of p-boronophenylalanine as potential boron carriers on boron neutron capture therapy for malignant brain tumors.
    Cancer research, 1996, May-01, Volume: 56, Issue:9

    Topics: Animals; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Cell Survival; Glioma; Humans; Hydroxylation; Male; Phenylalanine; Radiation-Sensitizing Agents; Rats; Rats, Inbred F344

1996
Enhanced delivery of boronophenylalanine for neutron capture therapy by means of intracarotid injection and blood-brain barrier disruption.
    Neurosurgery, 1996, Volume: 38, Issue:5

    Topics: Animals; Blood-Brain Barrier; Boron Compounds; Brain; Brain Neoplasms; Carotid Arteries; Dominance, Cerebral; Glioma; Injections, Intra-Arterial; Mannitol; Neoplasm Transplantation; Neutron Capture Therapy; Phenylalanine; Radiation-Sensitizing Agents; Rats; Rats, Inbred F344; Tissue Distribution; Tumor Cells, Cultured

1996
Boron neutron capture therapy of brain tumors: enhanced survival following intracarotid injection of either sodium borocaptate or boronophenylalanine with or without blood-brain barrier disruption.
    Cancer research, 1997, Mar-15, Volume: 57, Issue:6

    Topics: Alpha Particles; Animals; Blood-Brain Barrier; Borohydrides; Boron Compounds; Boron Neutron Capture Therapy; Brain; Brain Neoplasms; Carotid Arteries; Glioma; Injections, Intra-Arterial; Mannitol; Phenylalanine; Rats; Rats, Inbred F344; Sulfhydryl Compounds

1997
Enhanced survival of glioma bearing rats following boron neutron capture therapy with blood-brain barrier disruption and intracarotid injection of boronophenylalanine.
    Journal of neuro-oncology, 1997, Volume: 33, Issue:1-2

    Topics: Animals; Blood-Brain Barrier; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Carotid Arteries; Fructose; Glioma; Humans; Infusions, Intra-Arterial; Injections, Intra-Arterial; Male; Mannitol; Phenylalanine; Rats; Rats, Inbred F344; Survival Rate; Tissue Distribution

1997
Fluorine-18-labeled fluoroboronophenylalanine PET in patients with glioma.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1998, Volume: 39, Issue:2

    Topics: Astrocytoma; Boron Compounds; Brain Neoplasms; Cerebrovascular Circulation; Fluorine Radioisotopes; Glioblastoma; Glioma; Humans; Phenylalanine; Radiopharmaceuticals; Tomography, Emission-Computed

1998
Positron emission tomography-based boron neutron capture therapy using boronophenylalanine for high-grade gliomas: part I.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1998, Volume: 4, Issue:8

    Topics: Boron; Boron Compounds; Boron Neutron Capture Therapy; Fluorine Radioisotopes; Glioma; Humans; Isotopes; Phenylalanine; Radiation-Sensitizing Agents; Tomography, Emission-Computed

1998
Positron emission tomography-based boron neutron capture therapy using boronophenylalanine for high-grade gliomas: part II.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1998, Volume: 4, Issue:8

    Topics: Boron; Boron Compounds; Boron Neutron Capture Therapy; Fluorine Radioisotopes; Glioma; Humans; Isotopes; Mathematical Computing; Phenylalanine; Radiation-Sensitizing Agents; Tomography, Emission-Computed

1998
Enhanced delivery of boronophenylalanine for neutron capture therapy of brain tumors using the bradykinin analog Cereport (Receptor-Mediated Permeabilizer-7).
    Neurosurgery, 1999, Volume: 44, Issue:2

    Topics: Animals; Boron Compounds; Boron Neutron Capture Therapy; Bradykinin; Brain Neoplasms; Carotid Arteries; Dose-Response Relationship, Drug; Glioma; Injections, Intra-Arterial; Injections, Intravenous; Phenylalanine; Radiation-Sensitizing Agents; Rats; Rats, Inbred F344; Tissue Distribution

1999
Boron neutron capture therapy of brain tumors: enhanced survival and cure following blood-brain barrier disruption and intracarotid injection of sodium borocaptate and boronophenylalanine.
    International journal of radiation oncology, biology, physics, 2000, Apr-01, Volume: 47, Issue:1

    Topics: Animals; Blood-Brain Barrier; Borohydrides; Boron Compounds; Boron Neutron Capture Therapy; Brain; Brain Neoplasms; Drug Screening Assays, Antitumor; Drug Therapy, Combination; Glioma; Injections, Intra-Arterial; Phenylalanine; Radiation-Sensitizing Agents; Radiobiology; Radiotherapy Dosage; Rats; Rats, Inbred F344; Sulfhydryl Compounds; Time Factors

2000
Improved survival after boron neutron capture therapy of brain tumors by Cereport-mediated blood-brain barrier modulation to enhance delivery of boronophenylalanine.
    Neurosurgery, 2000, Volume: 47, Issue:1

    Topics: Animals; Blood-Brain Barrier; Boron Compounds; Boron Neutron Capture Therapy; Bradykinin; Brain Neoplasms; Glioma; Phenylalanine; Radiation-Sensitizing Agents; Rats; Rats, Inbred F344; Survival Rate; Tissue Distribution

2000
Boron neutron capture therapy for murine malignant gliomas.
    Cancer research, 1992, Sep-01, Volume: 52, Issue:17

    Topics: Animals; Boron Compounds; Brain; Brain Neoplasms; Glioma; Mice; Mice, Inbred C57BL; Neutrons; Phenylalanine; Radiation-Sensitizing Agents; Survival Analysis

1992
Control of intracerebral gliosarcomas in rats by boron neutron capture therapy with p-boronophenylalanine.
    Radiation research, 1992, Volume: 129, Issue:3

    Topics: Animals; Boron Compounds; Brain Neoplasms; Glioma; Male; Neoplasm Transplantation; Neutrons; Phenylalanine; Rats; Rats, Inbred F344

1992
Selective delivery of boron by the melanin precursor analogue p-boronophenylalanine to tumors other than melanoma.
    Cancer research, 1990, Jan-01, Volume: 50, Issue:1

    Topics: Animals; Boron Compounds; Brain Neoplasms; Cell Line; Drug Carriers; Glioma; Humans; Isotopes; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Mice, Nude; Neutrons; Phenylalanine; Rats; Tissue Distribution; Transplantation, Heterologous

1990