4-boronophenylalanine has been researched along with Brain Neoplasms in 50 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 22 (44.00) | 18.2507 |
2000's | 21 (42.00) | 29.6817 |
2010's | 6 (12.00) | 24.3611 |
2020's | 1 (2.00) | 2.80 |
Authors | Studies |
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Adams, DM; Barth, RF; Cai, J; Hariharan, JR; Radcliffe, K; Soloway, AH; Wyzlic, IM | 1 |
Fukuda, H; Hiratsuka, J | 1 |
Hattori, Y; Hermawan, A; Ishimura, M; Kirihata, M; Meiyanto, E; Ohta, Y; Qodria, L; Ramadani, RD; Susidarti, RA; Utomo, RY | 1 |
Moss, RL; Sauerwein, WA; Wittig, A | 1 |
Barth, RF; Chandra, S; Haider, SA; Huo, T; Kabalka, GW; Shaikh, AL; Yang, W | 1 |
Chang, CW; Chang, WY; Chen, JC; Li, JJ; Wang, HE; Yang, FY | 1 |
Barth, RF | 2 |
Cruickshank, GS; Detta, A | 1 |
Bozzali, M; Cametti, C; Capuani, S; D'Amore, E; Gili, T; Lazzarino, G; Maraviglia, B; Muolo, M; Pastore, FS; Porcari, P; Russo, S | 1 |
Kumada, H; Matsuda, M; Matsumura, A; Nakai, K; Shirakawa, M; Tsurubuchi, T; Yamamoto, T | 1 |
Doi, A; Hiramatsu, R; Iida, K; Imahori, Y; Kawabata, S; Kirihata, M; Kumada, H; Kuroda, Y; Kuroiwa, T; Maruhashi, A; Masunaga, S; Michiue, H; Miyata, S; Miyatake, S; Nonoguchi, N; Ono, K; Sakurai, Y; Suzuki, M; Yokoyama, K | 1 |
Boddy, A; Braithwaite, R; Chester, M; Chopra, A; Croswell, G; Cruickshank, GS; Detta, A; Doran, J; Elliot, M; Ford, S; Ghani, Z; Graham, N; Green, S; Halbert, G; Hardie, J; James, ND; Lockyer, N; Ngoga, D; Sheehan, TM; Steinfeldt, H; Sugar, R; Vickerman, J; Wojnecki, C | 1 |
Barth, RF; Binns, P; Riley, K; Tjarks, W; Wu, G; Yang, W | 1 |
Cheng, X; Guo, G; Jiang, X; Mao, X; Wang, P; Zhang, W; Zhang, X; Zhen, H | 1 |
Chandra, S; Coderre, JA; Kabalka, GW; Lorey, DR; Smith, DR | 1 |
Coderre, JA; Micca, PL; Morris, GM; Nawrocky, MM; Weissfloch, LE | 1 |
Al-Madhoun, AS; Barth, RF; Byun, Y; Chandra, S; Eriksson, S; Johnsamuel, J; Smith, DR; Tjarks, W; Yang, W | 1 |
Bergenheim, AT; Capala, J; Henriksson, R; Roslin, M | 1 |
Brun, A; H-Stenstam, B; Pellettieri, L; Rezaei, A; Sköld, K | 1 |
Barth, RF; Chandra, S; Lorey, DR; Tjarks, W | 1 |
Flam, F | 1 |
Fukuda, H; Ichihashi, M; Mishima, Y | 1 |
Bailey, MQ; Barth, RF; Coderre, JA; Matalka, KZ; Moeschberger, ML; Rofstad, EK; Soloway, AH; Staubus, AE | 2 |
Allen, BJ; Jones, R; Mallesch, JL; McCarthy, WH; Moore, DE; Stening, WA | 1 |
Cai, J; Iwamoto, S; Kikuchi, H; Nemoto, H; Oda, Y; Ono, K; Takagaki, M; Yamamoto, Y | 1 |
Barth, RF; Carpenter, DE; Goodman, JH; Moeschberger, ML; Yang, W | 1 |
Barth, RF; Goodman, JH; Joel, DD; Moeschberger, ML; Nawrocky, MM; Rotaru, JH; Soloway, AH; Yang, W | 1 |
Barth, RF; Goodman, JH; Joel, DD; Moeschberger, ML; Nawrocky, MM; Rotaru, JH; Yang, W | 1 |
Bergland, R; Capala, J; Chadha, M; Chanana, AD; Coderre, JA; Elowitz, EH; Joel, DD; Liu, HB; Slatkin, DN | 1 |
Buonocore, E; Dyke, JP; Hübner, KF; Kabalka, GW; Longford, CP; Reddy, NK; Reid, WS; Roberts, TG; Smith, GT | 1 |
Fujii, R; Ido, T; Imahori, Y; Kusuki, T; Ohmori, Y; Ono, K; Ueda, S | 1 |
Bergland, RM; Chadha, M; Chanana, AD; Coderre, JA; Elowitz, EH; Joel, DD | 1 |
Capala, J; Chadha, M; Chanana, AD; Coderre, JA; Elowitz, EH; Iwai, J; Joel, DD; Liu, HB; Wielopolski, L | 1 |
Barth, RF; Bartus, RT; Goodman, JH; Moeschberger, ML; Yang, W | 1 |
Coderre, JA; Joel, DD; Micca, PL; Nawrocky, MM | 1 |
Ye, SJ | 1 |
Aziz, T; Capala, J; Chanana, A; Diaz, A; Peress, NS | 1 |
Barth, RF; Boesel, CP; Goodman, JH; Joel, DD; Moeschberger, ML; Nawrocky, MM; Ono, K; Rotaru, JH; Soloway, AH; Yang, W | 1 |
Barth, RF; Bartus, RT; Coderre, JA; Ferketich, AK; Goodman, JH; Moeschberger, ML; Nawrocky, MM; Rotaru, JH; Yang, W | 1 |
Barth, RF; Boesel, CP; Bresnahan, JC; Goettl, VM; Hadjiconstantinou, M; Joel, DD; Nawrocky, MM; Rotaru, JH; Wilkie, DA; Yang, W | 1 |
Busse, PM; Kiger, WS; Palmer, MR; Riley, KJ; Zamenhof, RG | 1 |
Barth, RF; Chandra, S; Coderre, JA; Joel, DD; Smith, DR; Yang, W | 1 |
Ehara, K; Hiratsuka, J; Iwakura, M; Kondoh, H; Mishima, Y; Tamaki, N | 1 |
Barth, RF; Bartus, RT; Coderre, JA; Ferketich, AK; Moeschberger, ML; Nawrocky, MM; Rofstad, EK; Rotaru, JH; Yang, W | 1 |
Adelman, LS; Cano, G; Harling, OK; Joyce, MA; Kerley, SE; Madoc-Jones, H; Saris, SC; Solares, GR; Wazer, DE; Zamenhof, RG | 1 |
Coderre, JA; Joel, DD; Micca, PL; Nawrocky, MM; Slatkin, DN | 1 |
Barth, RF; Fairchild, RG; Soloway, AH | 1 |
Coderre, JA; Fairchild, RG; Fand, I; Glass, JD; Joel, DD; Micca, PL | 1 |
2 review(s) available for 4-boronophenylalanine and Brain Neoplasms
Article | Year |
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Pharmacokinetics of
Topics: Boron; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Glioblastoma; Humans; Isotopes; Melanoma; Neoplasms; Phenylalanine; Positron-Emission Tomography | 2020 |
Boron neutron capture therapy at the crossroads: challenges and opportunities.
Topics: Animals; Borohydrides; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Fast Neutrons; Glioma; Humans; Nuclear Reactors; Phenylalanine; Radiation-Sensitizing Agents; Radiotherapy Planning, Computer-Assisted; Randomized Controlled Trials as Topic; Rats; Sulfhydryl Compounds | 2009 |
5 trial(s) available for 4-boronophenylalanine and Brain Neoplasms
Article | Year |
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A cancer research UK pharmacokinetic study of BPA-mannitol in patients with high grade glioma to optimise uptake parameters for clinical trials of BNCT.
Topics: Aged; Blood-Brain Barrier; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Glioma; Humans; Male; Mannitol; Phenylalanine; Radiation-Sensitizing Agents; United Kingdom | 2009 |
Neuropathological postmortem evaluation of BNCT for GBM.
Topics: Aged; Boron Compounds; Boron Neutron Capture Therapy; Brain; Brain Neoplasms; Follow-Up Studies; Glioblastoma; Humans; Middle Aged; Phenylalanine; Radiotherapy Dosage; Treatment Outcome | 2007 |
Boron neutron capture therapy for glioblastoma multiforme using p-boronophenylalanine and epithermal neutrons: trial design and early clinical results.
Topics: Adult; Boron Compounds; Boron Neutron Capture Therapy; Brain; Brain Neoplasms; Glioblastoma; Humans; Magnetic Resonance Imaging; Neutrons; Nuclear Reactors; Phenylalanine; Tissue Distribution | 1997 |
Boron neutron-capture therapy (BNCT) for glioblastoma multiforme (GBM) using the epithermal neutron beam at the Brookhaven National Laboratory.
Topics: Aged; Boron; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Dose-Response Relationship, Radiation; Feasibility Studies; Glioblastoma; Humans; Middle Aged; Phenylalanine; Radiation-Sensitizing Agents; Radiotherapy Dosage; Treatment Outcome | 1998 |
A pharmacokinetic model for the concentration of 10B in blood after boronophenylalanine-fructose administration in humans.
Topics: Adult; Aged; Boron; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Female; Fructose; Glioblastoma; Humans; Infusions, Intravenous; Male; Melanoma; Middle Aged; Models, Biological; Phenylalanine; Skin Neoplasms | 2001 |
43 other study(ies) available for 4-boronophenylalanine and Brain Neoplasms
Article | Year |
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Boron-containing polyamines as DNA targeting agents for neutron capture therapy of brain tumors: synthesis and biological evaluation.
Topics: Animals; Antineoplastic Agents; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; DNA; Female; Glioma; Pregnancy; Rats; Rats, Inbred F344; Spermidine; Spermine; Structure-Activity Relationship; Tumor Cells, Cultured | 1997 |
Cellular uptake evaluation of pentagamaboronon-0 (PGB-0) for boron neutron capture therapy (BNCT) against breast cancer cells.
Topics: Biological Transport; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Curcumin; Female; Humans; Phenylalanine; Radiation-Sensitizing Agents | 2019 |
Glioblastoma, brain metastases and soft tissue sarcoma of extremities: candidate tumors for BNCT.
Topics: Animals; Borohydrides; Boron Compounds; Brain Neoplasms; Cell Line, Tumor; Extremities; Glioblastoma; Humans; Male; Mice; Mice, Nude; Phenylalanine; Radiotherapy Dosage; Sarcoma; Sulfhydryl Compounds; Tissue Distribution | 2014 |
Effects of l-DOPA pre-loading on the uptake of boronophenylalanine using the F98 glioma and B16 melanoma models.
Topics: Animals; Boron Compounds; Brain Neoplasms; Drug Synergism; Female; Glioma; Levodopa; Melanoma; Metabolic Clearance Rate; Mice; Mice, Inbred C57BL; Organ Specificity; Phenylalanine; Premedication; Tissue Distribution; Treatment Outcome | 2014 |
Pharmacokinetic analysis and uptake of 18F-FBPA-Fr after ultrasound-induced blood-brain barrier disruption for potential enhancement of boron delivery for neutron capture therapy.
Topics: Animals; Apoptosis; Blood-Brain Barrier; Boron Compounds; Brain Neoplasms; Drug Delivery Systems; Glioma; Glycopeptides; In Situ Nick-End Labeling; Male; Neoplasm Transplantation; Neutron Capture Therapy; Phenylalanine; Positron-Emission Tomography; Radiopharmaceuticals; Rats; Rats, Inbred F344; Ultrasonics | 2014 |
From the laboratory to the clinic: How translational studies in animals have lead to clinical advances in boron neutron capture therapy.
Topics: Animals; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Melanoma; Phenylalanine; Translational Research, Biomedical | 2015 |
L-amino acid transporter-1 and boronophenylalanine-based boron neutron capture therapy of human brain tumors.
Topics: Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Cell Proliferation; Humans; Immunohistochemistry; Large Neutral Amino Acid-Transporter 1; Phenylalanine; Proliferating Cell Nuclear Antigen | 2009 |
Boronophenylalanine uptake in C6 glioma model is dramatically increased by L-DOPA preloading.
Topics: Animals; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Cell Line, Tumor; Glioma; In Vitro Techniques; Levodopa; Magnetic Resonance Imaging; Male; Phenylalanine; Radiation-Sensitizing Agents; Rats; Rats, Wistar | 2009 |
Dose distribution and clinical response of glioblastoma treated with boron neutron capture therapy.
Topics: Adult; Aged; Borohydrides; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Disease-Free Survival; Female; Glioblastoma; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Phenylalanine; Photons; Radiotherapy Dosage; Retrospective Studies; Sulfhydryl Compounds; Survival Rate; Treatment Failure | 2009 |
Survival benefit from boron neutron capture therapy for the newly diagnosed glioblastoma patients.
Topics: Borohydrides; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Clinical Protocols; Combined Modality Therapy; Glioblastoma; Humans; Japan; Phenylalanine; Prognosis; Radiation-Sensitizing Agents; Sulfhydryl Compounds; Survival Rate | 2009 |
Boron neutron capture therapy of EGFR or EGFRvIII positive gliomas using either boronated monoclonal antibodies or epidermal growth factor as molecular targeting agents.
Topics: Animals; Antibodies, Monoclonal; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Cell Line, Tumor; ErbB Receptors; Glioma; Head and Neck Neoplasms; Humans; Phenylalanine; Radiation-Sensitizing Agents; Radiometry; Rats; Rats, Inbred F344 | 2009 |
Boron neutron capture therapy induces apoptosis of glioma cells through Bcl-2/Bax.
Topics: Apoptosis; bcl-2-Associated X Protein; Blotting, Western; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Shape; Cell Survival; Cobalt Radioisotopes; Dose-Response Relationship, Radiation; Flow Cytometry; Gamma Rays; Glioblastoma; Humans; Microscopy, Electron, Transmission; Neutrons; Phenylalanine; Proto-Oncogene Proteins c-bcl-2; Radiation-Sensitizing Agents; Time Factors | 2010 |
Imaging of fluorine and boron from fluorinated boronophenylalanine in the same cell at organelle resolution by correlative ion microscopy and confocal laser scanning microscopy.
Topics: Boron; Boron Compounds; Brain Neoplasms; Fluorine; Glioblastoma; Humans; Image Processing, Computer-Assisted; Ions; Microscopy, Confocal; Mitochondria; Models, Chemical; Phenylalanine; Radiation-Sensitizing Agents; Time Factors; Tomography, Emission-Computed; Tumor Cells, Cultured | 2002 |
Long-term infusions of p-boronophenylalanine for boron neutron capture therapy: evaluation using rat brain tumor and spinal cord models.
Topics: Animals; Boron Compounds; Boron Neutron Capture Therapy; Brain; Brain Neoplasms; Dose-Response Relationship, Radiation; Male; Phenylalanine; Radiation-Sensitizing Agents; Radiometry; Rats; Rats, Inbred F344; Spinal Cord; Time Factors; X-Rays | 2002 |
Boron-containing nucleosides as potential delivery agents for neutron capture therapy of brain tumors.
Topics: Animals; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Cell Division; Glioma; Humans; Male; Mice; Mice, Inbred C3H; Mice, Nude; Middle Aged; Phenylalanine; Phosphorylation; Rats; Rats, Inbred F344; Spectrometry, Mass, Secondary Ion; Subcellular Fractions; Thymidine; Thymidine Kinase | 2004 |
Distribution of BPA and metabolic assessment in glioblastoma patients during BNCT treatment: a microdialysis study.
Topics: Blood Glucose; Boron Compounds; Boron Neutron Capture Therapy; Brain; Brain Neoplasms; Glioblastoma; Humans; Microdialysis; Phenylalanine; Radiation-Sensitizing Agents | 2005 |
Quantitative subcellular imaging of boron compounds in individual mitotic and interphase human glioblastoma cells with imaging secondary ion mass spectrometry (SIMS).
Topics: Boron; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Cell Line; Glioblastoma; Humans; Interphase; Mitosis; Phenylalanine; Spectrometry, Mass, Secondary Ion | 2008 |
Cancer treatment. Will history repeat for boron capture therapy?
Topics: Animals; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Clinical Trials as Topic; Glioblastoma; Humans; Japan; Phenylalanine; Radiation-Sensitizing Agents; United States | 1994 |
[Neutron capture therapy for cancer].
Topics: Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Humans; Infusions, Intravenous; Melanoma; Phenylalanine; Skin Neoplasms | 1994 |
A nude rat model for neutron capture therapy of human intracerebral melanoma.
Topics: Animals; Boron Compounds; Boron Neutron Capture Therapy; Brain; Brain Neoplasms; Female; Humans; Male; Melanoma; Mice; Middle Aged; Neoplasm Transplantation; Phenylalanine; Rats; Rats, Nude; Tumor Cells, Cultured | 1994 |
The pharmacokinetics of p-Boronophenylalanine.fructose in human patients with glioma and metastatic melanoma.
Topics: Boron; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Glioma; Humans; Melanoma; Phenylalanine; Radiation-Sensitizing Agents | 1994 |
Boron neutron capture therapy of intracerebral melanoma using boronophenylalanine as a capture agent.
Topics: Animals; Boron; Boron Compounds; Boron Neutron Capture Therapy; Brain; Brain Neoplasms; Cell Survival; Humans; Male; Melanoma; Middle Aged; Phenylalanine; Radiation-Sensitizing Agents; Radiotherapy Dosage; Rats; Rats, Nude; Tissue Distribution | 1993 |
Hydroxylforms of p-boronophenylalanine as potential boron carriers on boron neutron capture therapy for malignant brain tumors.
Topics: Animals; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Cell Survival; Glioma; Humans; Hydroxylation; Male; Phenylalanine; Radiation-Sensitizing Agents; Rats; Rats, Inbred F344 | 1996 |
Enhanced delivery of boronophenylalanine for neutron capture therapy by means of intracarotid injection and blood-brain barrier disruption.
Topics: Animals; Blood-Brain Barrier; Boron Compounds; Brain; Brain Neoplasms; Carotid Arteries; Dominance, Cerebral; Glioma; Injections, Intra-Arterial; Mannitol; Neoplasm Transplantation; Neutron Capture Therapy; Phenylalanine; Radiation-Sensitizing Agents; Rats; Rats, Inbred F344; Tissue Distribution; Tumor Cells, Cultured | 1996 |
Boron neutron capture therapy of brain tumors: enhanced survival following intracarotid injection of either sodium borocaptate or boronophenylalanine with or without blood-brain barrier disruption.
Topics: Alpha Particles; Animals; Blood-Brain Barrier; Borohydrides; Boron Compounds; Boron Neutron Capture Therapy; Brain; Brain Neoplasms; Carotid Arteries; Glioma; Injections, Intra-Arterial; Mannitol; Phenylalanine; Rats; Rats, Inbred F344; Sulfhydryl Compounds | 1997 |
Enhanced survival of glioma bearing rats following boron neutron capture therapy with blood-brain barrier disruption and intracarotid injection of boronophenylalanine.
Topics: Animals; Blood-Brain Barrier; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Carotid Arteries; Fructose; Glioma; Humans; Infusions, Intra-Arterial; Injections, Intra-Arterial; Male; Mannitol; Phenylalanine; Rats; Rats, Inbred F344; Survival Rate; Tissue Distribution | 1997 |
Evaluation of fluorine-18-BPA-fructose for boron neutron capture treatment planning.
Topics: Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Female; Fluorine Radioisotopes; Fructose; Glioblastoma; Humans; Middle Aged; Phenylalanine; Radiation-Sensitizing Agents; Tomography, Emission-Computed | 1997 |
Fluorine-18-labeled fluoroboronophenylalanine PET in patients with glioma.
Topics: Astrocytoma; Boron Compounds; Brain Neoplasms; Cerebrovascular Circulation; Fluorine Radioisotopes; Glioblastoma; Glioma; Humans; Phenylalanine; Radiopharmaceuticals; Tomography, Emission-Computed | 1998 |
Biodistribution of p-boronophenylalanine in patients with glioblastoma multiforme for use in boron neutron capture therapy.
Topics: Boron Compounds; Brain; Brain Neoplasms; Craniotomy; Glioblastoma; Humans; Injections, Intravenous; Neutron Capture Therapy; Osmolar Concentration; Phenylalanine; Radiation-Sensitizing Agents; Scalp; Tissue Distribution | 1998 |
Enhanced delivery of boronophenylalanine for neutron capture therapy of brain tumors using the bradykinin analog Cereport (Receptor-Mediated Permeabilizer-7).
Topics: Animals; Boron Compounds; Boron Neutron Capture Therapy; Bradykinin; Brain Neoplasms; Carotid Arteries; Dose-Response Relationship, Drug; Glioma; Injections, Intra-Arterial; Injections, Intravenous; Phenylalanine; Radiation-Sensitizing Agents; Rats; Rats, Inbred F344; Tissue Distribution | 1999 |
Effect of dose and infusion time on the delivery of p-boronophenylalanine for neutron capture therapy.
Topics: Animals; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Glioblastoma; Gliosarcoma; Infusions, Intravenous; Metabolic Clearance Rate; Phenylalanine; Radiation-Sensitizing Agents; Rats; Tissue Distribution; Tumor Cells, Cultured | 1999 |
Boron self-shielding effects on dose delivery of neutron capture therapy using epithermal beam and boronophenylalanine.
Topics: Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Humans; Models, Statistical; Monte Carlo Method; Phantoms, Imaging; Phenylalanine; Radiation Protection; Radiation-Sensitizing Agents; Radiotherapy Dosage | 1999 |
Postmortem neuropathological features secondary to boron neutron capture therapy for glioblastoma multiforme.
Topics: Adult; Aged; Boron Compounds; Boron Neutron Capture Therapy; Brain; Brain Neoplasms; Dose-Response Relationship, Radiation; Female; Glioblastoma; Humans; Lewy Bodies; Male; Middle Aged; Nerve Degeneration; Neurofibrillary Tangles; Neurons; Phenylalanine; Radiation-Sensitizing Agents | 2000 |
Boron neutron capture therapy of brain tumors: enhanced survival and cure following blood-brain barrier disruption and intracarotid injection of sodium borocaptate and boronophenylalanine.
Topics: Animals; Blood-Brain Barrier; Borohydrides; Boron Compounds; Boron Neutron Capture Therapy; Brain; Brain Neoplasms; Drug Screening Assays, Antitumor; Drug Therapy, Combination; Glioma; Injections, Intra-Arterial; Phenylalanine; Radiation-Sensitizing Agents; Radiobiology; Radiotherapy Dosage; Rats; Rats, Inbred F344; Sulfhydryl Compounds; Time Factors | 2000 |
Improved survival after boron neutron capture therapy of brain tumors by Cereport-mediated blood-brain barrier modulation to enhance delivery of boronophenylalanine.
Topics: Animals; Blood-Brain Barrier; Boron Compounds; Boron Neutron Capture Therapy; Bradykinin; Brain Neoplasms; Glioma; Phenylalanine; Radiation-Sensitizing Agents; Rats; Rats, Inbred F344; Survival Rate; Tissue Distribution | 2000 |
Boron neutron capture therapy of brain tumors: functional and neuropathologic effects of blood-brain barrier disruption and intracarotid injection of sodium borocaptate and boronophenylalanine.
Topics: Animals; Blood-Brain Barrier; Borohydrides; Boron Compounds; Boron Neutron Capture Therapy; Brain; Brain Neoplasms; Carotid Artery, Internal; Cerebral Hemorrhage; Cognition; Eye; Eye Diseases; Injections, Intra-Arterial; Male; Motor Activity; Neurotoxins; Neutrons; Phenylalanine; Radiation-Sensitizing Agents; Rats; Rats, Inbred F344; Sulfhydryl Compounds; Tissue Distribution | 2000 |
Quantitative imaging and microlocalization of boron-10 in brain tumors and infiltrating tumor cells by SIMS ion microscopy: relevance to neutron capture therapy.
Topics: Animals; Boron; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Drug Administration Schedule; Gliosarcoma; Infusions, Intravenous; Isotopes; Male; Phenylalanine; Rats; Rats, Inbred F344; Spectrometry, Mass, Secondary Ion | 2001 |
Effect of boron neutron capture therapy for melanotic and amelanotic melanoma transplanted into mouse brain.
Topics: Animals; Boron; Boron Compounds; Boron Neutron Capture Therapy; Brain; Brain Neoplasms; Isotopes; Melanins; Melanoma, Amelanotic; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Neoplasm Transplantation; Phenylalanine; Radiation-Sensitizing Agents; Tumor Cells, Cultured | 2002 |
Neutron capture therapy of intracerebral melanoma: enhanced survival and cure after blood-brain barrier opening to improve delivery of boronophenylalanine.
Topics: Animals; Blood-Brain Barrier; Boron Compounds; Boron Neutron Capture Therapy; Bradykinin; Brain Neoplasms; Humans; Mannitol; Melanoma; Osmosis; Phenylalanine; Radiation-Sensitizing Agents; Rats; Rats, Nude | 2002 |
Boron neutron capture therapy for murine malignant gliomas.
Topics: Animals; Boron Compounds; Brain; Brain Neoplasms; Glioma; Mice; Mice, Inbred C57BL; Neutrons; Phenylalanine; Radiation-Sensitizing Agents; Survival Analysis | 1992 |
Control of intracerebral gliosarcomas in rats by boron neutron capture therapy with p-boronophenylalanine.
Topics: Animals; Boron Compounds; Brain Neoplasms; Glioma; Male; Neoplasm Transplantation; Neutrons; Phenylalanine; Rats; Rats, Inbred F344 | 1992 |
Boron neutron capture therapy for cancer.
Topics: Alpha Particles; Animals; Antibodies, Monoclonal; Boron; Boron Compounds; Brain Neoplasms; Glioblastoma; Humans; Immunotoxins; Isotopes; Melanoma; Mice; Neoplasms; Neutrons; Phenylalanine; Radiation Dosage | 1990 |
Selective delivery of boron by the melanin precursor analogue p-boronophenylalanine to tumors other than melanoma.
Topics: Animals; Boron Compounds; Brain Neoplasms; Cell Line; Drug Carriers; Glioma; Humans; Isotopes; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Mice, Nude; Neutrons; Phenylalanine; Rats; Tissue Distribution; Transplantation, Heterologous | 1990 |