4-aminopyridine has been researched along with Trigeminal Neuralgia in 3 studies
Trigeminal Neuralgia: A syndrome characterized by recurrent episodes of excruciating pain lasting several seconds or longer in the sensory distribution of the TRIGEMINAL NERVE. Pain may be initiated by stimulation of trigger points on the face, lips, or gums or by movement of facial muscles or chewing. Associated conditions include MULTIPLE SCLEROSIS, vascular anomalies, ANEURYSMS, and neoplasms. (Adams et al., Principles of Neurology, 6th ed, p187)
| Excerpt | Relevance | Reference |
|---|---|---|
| "To determine the effect of dalfampridine (4-aminopyridine), a broad-spectrum, voltage-dependent potassium channel blocker, on patients with trigeminal nerve dysfunction due to multiple sclerosis (MS)." | 3.80 | Dalfampridine may activate latent trigeminal neuralgia in patients with multiple sclerosis. ( Birnbaum, G; Iverson, J, 2014) |
| "Trigeminal neuralgia is a paroxysmal disorder with severely disabling facial pain and thus continues to be a real therapeutic challenge." | 1.36 | [BK(Ca) channel agonist NS1619 and Kv channel antagonist 4-AP on the facial mechanical pain threshold in a rat model of chronic constriction injury of the infraorbital nerve]. ( Li, N; Liu, CY; Ma, B; Zhao, YF, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Birnbaum, G | 1 |
| Iverson, J | 1 |
| Montcuquet, A | 1 |
| Magy, L | 1 |
| Liu, CY | 1 |
| Li, N | 1 |
| Zhao, YF | 1 |
| Ma, B | 1 |
3 other studies available for 4-aminopyridine and Trigeminal Neuralgia
| Article | Year |
|---|---|
Dalfampridine may activate latent trigeminal neuralgia in patients with multiple sclerosis.
Topics: 4-Aminopyridine; Female; Humans; Male; Middle Aged; Multiple Sclerosis; Potassium Channel Blockers; | 2014 |
[Recurrence and de novo trigeminal neuralgia induced by fampridine].
Topics: 4-Aminopyridine; Adult; Aged; Female; Humans; Multiple Sclerosis; Recurrence; Trigeminal Neuralgia | 2015 |
[BK(Ca) channel agonist NS1619 and Kv channel antagonist 4-AP on the facial mechanical pain threshold in a rat model of chronic constriction injury of the infraorbital nerve].
Topics: 4-Aminopyridine; Animals; Benzimidazoles; Constriction; Facial Pain; Injections, Intralesional; Kv1. | 2010 |