4-aminopyridine has been researched along with Spastic Paraplegia, Hereditary in 2 studies
Spastic Paraplegia, Hereditary: A group of inherited diseases that share similar phenotypes but are genetically diverse. Different genetic loci for autosomal recessive, autosomal dominant, and x-linked forms of hereditary spastic paraplegia have been identified. Clinically, patients present with slowly progressive distal limb weakness and lower extremity spasticity. Peripheral sensory neurons may be affected in the later stages of the disease. (J Neurol Neurosurg Psychiatry 1998 Jan;64(1):61-6; Curr Opin Neurol 1997 Aug;10(4):313-8)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Selcuk Muhtaroglu, F | 1 |
| Belgen Kaygisiz, B | 1 |
| Usar Incirli, S | 1 |
| Kahraman, T | 1 |
| Béreau, M | 1 |
| Anheim, M | 1 |
| Chanson, JB | 1 |
| Tio, G | 1 |
| Echaniz-Laguna, A | 1 |
| Depienne, C | 1 |
| Collongues, N | 1 |
| de Sèze, J | 1 |
1 trial available for 4-aminopyridine and Spastic Paraplegia, Hereditary
| Article | Year |
|---|---|
Dalfampridine as a promising agent in the management of hereditary spastic paraplegia: A triple-blinded, randomized, placebo-controlled pilot trial.
Topics: 4-Aminopyridine; Humans; Muscle Spasticity; Pilot Projects; Spastic Paraplegia, Hereditary; Walking | 2023 |
1 other study available for 4-aminopyridine and Spastic Paraplegia, Hereditary
| Article | Year |
|---|---|
Dalfampridine in hereditary spastic paraplegia: a prospective, open study.
Topics: 4-Aminopyridine; Adult; Aged; Alkaloids; Analysis of Variance; Female; Follow-Up Studies; Humans; Ma | 2015 |