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4-aminopyridine and Pulmonary Hypertension

4-aminopyridine has been researched along with Pulmonary Hypertension in 10 studies

Research Excerpts

ExcerptRelevanceReference
"4-Aminopyridine (4-AP) is a recent treatment indicated to improve walking in patient with multiple sclerosis."7.91Pulmonary arterial hypertension in patient treated for multiple sclerosis with 4-aminopyridine. ( Chabot, F; Chaouat, A; Gomez, E; Guillaumot, A; Petitpain, N; Ribeiro Baptista, B; Valentin, S; Yelehé-Okouma, M, 2019)
"4-Aminopyridine (4-AP) is a recent treatment indicated to improve walking in patient with multiple sclerosis."3.91Pulmonary arterial hypertension in patient treated for multiple sclerosis with 4-aminopyridine. ( Chabot, F; Chaouat, A; Gomez, E; Guillaumot, A; Petitpain, N; Ribeiro Baptista, B; Valentin, S; Yelehé-Okouma, M, 2019)
"The effects of the outward rectifying potassium channel blocker, 4-aminopyridine, on contractile tone and on contractile responses to the spasmogens, 5-hydroxytryptamine and endothelin-1, were examined in pulmonary arteries (main and intralobar) and systemic vessels (aorta and mesenteric artery) from rats with and without hypoxic pulmonary hypertension."3.70Functional effects of 4-aminopyridine (4-AP) on pulmonary and systemic vessels from normoxic control and hypoxic pulmonary hypertensive rats. ( Doggrell, SA; Gambino, A; Wanstall, JC, 1999)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (10.00)18.2507
2000's6 (60.00)29.6817
2010's3 (30.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ribeiro Baptista, B1
Petitpain, N1
Gomez, E1
Yelehé-Okouma, M1
Valentin, S1
Guillaumot, A1
Chabot, F1
Chaouat, A1
Antigny, F1
Chaumais, MC1
Humbert, M1
Montani, D1
Lv, Y1
Tang, LL1
Wei, JK1
Xu, XF1
Gu, W1
Fu, LC1
Zhang, LY1
Du, LZ1
Hyvelin, JM1
Gautier, M1
Lemaire, MC1
Bonnet, P1
Eder, V1
Olschewski, A1
Hong, Z2
Linden, BC1
Porter, VA1
Weir, EK2
Cornfield, DN1
Brevnova, EE1
Platoshyn, O1
Zhang, S1
Yuan, JX1
Rezaie-Majd, S1
Murar, J1
Nelson, DP1
Kelly, RF1
Lang, IM1
Varghese, A1
Fike, CD1
Kaplowitz, MR1
Zhang, Y1
Madden, JA1
Doggrell, SA1
Wanstall, JC1
Gambino, A1
Bonnet, S1
Dubuis, E1
Vandier, C1
Martin, S1
Marthan, R1
Savineau, JP1

Other Studies

10 other studies available for 4-aminopyridine and Pulmonary Hypertension

ArticleYear
Pulmonary arterial hypertension in patient treated for multiple sclerosis with 4-aminopyridine.
    Fundamental & clinical pharmacology, 2019, Volume: 33, Issue:1

    Topics: 4-Aminopyridine; Antihypertensive Agents; Dyspnea; Female; Humans; Hypertension, Pulmonary; Middle A

2019
Pulmonary arterial hypertension in patient treated for multiple sclerosis with 4-aminopyridine.
    Fundamental & clinical pharmacology, 2019, Volume: 33, Issue:4

    Topics: 4-Aminopyridine; Humans; Hypertension, Pulmonary; Multiple Sclerosis; Pulmonary Arterial Hypertensio

2019
Decreased Kv1.5 expression in intrauterine growth retardation rats with exaggerated pulmonary hypertension.
    American journal of physiology. Lung cellular and molecular physiology, 2013, Volume: 305, Issue:11

    Topics: 4-Aminopyridine; Acetylcholine; Animals; Barium Compounds; Cell Hypoxia; Cells, Cultured; Chlorides;

2013
Adaptative modifications of right coronary myocytes voltage-gated K+ currents in rat with hypoxic pulmonary hypertension.
    Pflugers Archiv : European journal of physiology, 2009, Volume: 457, Issue:4

    Topics: 4-Aminopyridine; Animals; Coronary Vessels; Hypertension, Pulmonary; Hypoxia; Male; Membrane Potenti

2009
Contribution of the K(Ca) channel to membrane potential and O2 sensitivity is decreased in an ovine PPHN model.
    American journal of physiology. Lung cellular and molecular physiology, 2002, Volume: 283, Issue:5

    Topics: 4-Aminopyridine; Animals; Animals, Newborn; Disease Models, Animal; Female; Gestational Age; Hyperte

2002
Overexpression of human KCNA5 increases IK V and enhances apoptosis.
    American journal of physiology. Cell physiology, 2004, Volume: 287, Issue:3

    Topics: 4-Aminopyridine; Animals; Apoptosis; Blotting, Western; Caspase 3; Caspases; Cells, Cultured; Chloro

2004
Increased release of serotonin from rat ileum due to dexfenfluramine.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2004, Volume: 287, Issue:5

    Topics: 4-Aminopyridine; Animals; Caffeine; Calcium; Chromatography, High Pressure Liquid; Cytosol; Dexfenfl

2004
Voltage-gated K+ channels at an early stage of chronic hypoxia-induced pulmonary hypertension in newborn piglets.
    American journal of physiology. Lung cellular and molecular physiology, 2006, Volume: 291, Issue:6

    Topics: 4-Aminopyridine; Animals; Arterioles; Disease Models, Animal; Hypertension, Pulmonary; Hypoxia; In V

2006
Functional effects of 4-aminopyridine (4-AP) on pulmonary and systemic vessels from normoxic control and hypoxic pulmonary hypertensive rats.
    Naunyn-Schmiedeberg's archives of pharmacology, 1999, Volume: 360, Issue:3

    Topics: 4-Aminopyridine; Animals; Aorta; Arteries; Endothelin-1; Hypertension, Pulmonary; Hypoxia; In Vitro

1999
Reversal of chronic hypoxia-induced alterations in pulmonary artery smooth muscle electromechanical coupling upon air breathing.
    Cardiovascular research, 2002, Volume: 53, Issue:4

    Topics: 4-Aminopyridine; Animals; Blood Pressure; Calcium; Cells, Cultured; Chronic Disease; Electrophysiolo

2002