4-aminopyridine has been researched along with Optic Neuritis in 3 studies
Optic Neuritis: Inflammation of the optic nerve. Commonly associated conditions include autoimmune disorders such as MULTIPLE SCLEROSIS, infections, and granulomatous diseases. Clinical features include retro-orbital pain that is aggravated by eye movement, loss of color vision, and contrast sensitivity that may progress to severe visual loss, an afferent pupillary defect (Marcus-Gunn pupil), and in some instances optic disc hyperemia and swelling. Inflammation may occur in the portion of the nerve within the globe (neuropapillitis or anterior optic neuritis) or the portion behind the globe (retrobulbar neuritis or posterior optic neuritis).
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 2 (66.67) | 2.80 |
| Authors | Studies |
|---|---|
| Dietrich, M | 1 |
| Koska, V | 1 |
| Hecker, C | 1 |
| Göttle, P | 1 |
| Hilla, AM | 1 |
| Heskamp, A | 1 |
| Lepka, K | 1 |
| Issberner, A | 1 |
| Hallenberger, A | 1 |
| Baksmeier, C | 1 |
| Steckel, J | 1 |
| Balk, L | 1 |
| Knier, B | 1 |
| Korn, T | 1 |
| Havla, J | 1 |
| Martínez-Lapiscina, EH | 1 |
| Solà-Valls, N | 1 |
| Manogaran, P | 1 |
| Olbert, ED | 1 |
| Schippling, S | 1 |
| Cruz-Herranz, A | 1 |
| Yiu, H | 1 |
| Button, J | 1 |
| Caldito, NG | 1 |
| von Gall, C | 1 |
| Mausberg, AK | 1 |
| Stettner, M | 1 |
| Zimmermann, HG | 1 |
| Paul, F | 1 |
| Brandt, AU | 1 |
| Küry, P | 1 |
| Goebels, N | 1 |
| Aktas, O | 1 |
| Berndt, C | 1 |
| Saidha, S | 1 |
| Green, AJ | 1 |
| Calabresi, PA | 1 |
| Fischer, D | 1 |
| Hartung, HP | 1 |
| Albrecht, P | 1 |
| Boffa, L | 1 |
| Albanese, M | 1 |
| Ziccardi, L | 1 |
| Aiello, F | 1 |
| Cesareo, M | 1 |
| Parisi, V | 1 |
| Mercuri, NB | 1 |
| van Diemen, HA | 1 |
| van Dongen, MM | 1 |
| Dammers, JW | 1 |
| Polman, CH | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Dalfampridine Treatment for Nonarteritic Anterior Ischemic Optic Neuropathy (NAION)[NCT01975324] | Phase 4 | 20 participants (Actual) | Interventional | 2013-07-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 other studies available for 4-aminopyridine and Optic Neuritis
| Article | Year |
|---|---|
Protective effects of 4-aminopyridine in experimental optic neuritis and multiple sclerosis.
Topics: 4-Aminopyridine; Adult; Aged; Animals; Encephalomyelitis, Autoimmune, Experimental; Female; Humans; | 2020 |
Fampridine improves acute optic neuritis contributing to a long-lasting recovery of nerve function.
Topics: 4-Aminopyridine; Humans; Optic Nerve; Optic Neuritis | 2021 |
Increased visual impairment after exercise (Uhthoff's phenomenon) in multiple sclerosis: therapeutic possibilities.
Topics: 4-Aminopyridine; Adult; Exercise; Exercise Test; Female; Humans; Male; Multiple Sclerosis; Optic Ner | 1992 |