4-aminopyridine has been researched along with Neurodegenerative Diseases in 5 studies
Neurodegenerative Diseases: Hereditary and sporadic conditions which are characterized by progressive nervous system dysfunction. These disorders are often associated with atrophy of the affected central or peripheral nervous system structures.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The voltage-gated K(+) (Kv) channel blocker 4-aminopyridine (4-AP) is used to target symptoms of the neuroinflammatory disease multiple sclerosis (MS)." | 7.79 | Inhibition of neuronal degenerin/epithelial Na+ channels by the multiple sclerosis drug 4-aminopyridine. ( Boiko, N; Eaton, BA; Kucher, V; Stockand, JD, 2013) |
| "The voltage-gated K(+) (Kv) channel blocker 4-aminopyridine (4-AP) is used to target symptoms of the neuroinflammatory disease multiple sclerosis (MS)." | 3.79 | Inhibition of neuronal degenerin/epithelial Na+ channels by the multiple sclerosis drug 4-aminopyridine. ( Boiko, N; Eaton, BA; Kucher, V; Stockand, JD, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (60.00) | 29.6817 |
| 2010's | 2 (40.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Boiko, N | 1 |
| Kucher, V | 1 |
| Eaton, BA | 1 |
| Stockand, JD | 1 |
| Ayala, GX | 1 |
| Tapia, R | 2 |
| Flynn, JM | 1 |
| Choi, SW | 1 |
| Day, NU | 1 |
| Gerencser, AA | 1 |
| Hubbard, A | 1 |
| Melov, S | 1 |
| Tebano, MT | 1 |
| Pintor, A | 1 |
| Frank, C | 1 |
| Domenici, MR | 1 |
| Martire, A | 1 |
| Pepponi, R | 1 |
| Potenza, RL | 1 |
| Grieco, R | 1 |
| Popoli, P | 1 |
| Mora, G | 1 |
5 other studies available for 4-aminopyridine and Neurodegenerative Diseases
| Article | Year |
|---|---|
Inhibition of neuronal degenerin/epithelial Na+ channels by the multiple sclerosis drug 4-aminopyridine.
Topics: 4-Aminopyridine; Animals; Animals, Newborn; CHO Cells; Cricetinae; Degenerin Sodium Channels; Drosop | 2013 |
HSP70 expression protects against hippocampal neurodegeneration induced by endogenous glutamate in vivo.
Topics: 4-Aminopyridine; Animals; Cell Count; Disease Models, Animal; Dizocilpine Maleate; Electroencephalog | 2008 |
Impaired spare respiratory capacity in cortical synaptosomes from Sod2 null mice.
Topics: 4-Aminopyridine; Animals; Biomimetics; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Cerebral | 2011 |
Adenosine A2A receptor blockade differentially influences excitotoxic mechanisms at pre- and postsynaptic sites in the rat striatum.
Topics: 4-Aminopyridine; Adenosine; Adenosine A2 Receptor Antagonists; Animals; Calcium; Corpus Striatum; Do | 2004 |
Effects of retigabine on the neurodegeneration and extracellular glutamate changes induced by 4-aminopyridine in rat hippocampus in vivo.
Topics: 4-Aminopyridine; Animals; Anticonvulsants; Carbamates; Drug Interactions; Electroencephalography; Ex | 2005 |