4-aminopyridine has been researched along with Muscular Atrophy in 3 studies
Muscular Atrophy: Derangement in size and number of muscle fibers occurring with aging, reduction in blood supply, or following immobilization, prolonged weightlessness, malnutrition, and particularly in denervation.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Although muscle atrophy occurs very rapidly after nerve injury, the effect of 4-AP on muscle atrophy and intrinsic muscle contractile function is largely unknown." | 1.51 | 4-Aminopyridine attenuates muscle atrophy after sciatic nerve crush injury in mice. ( Chakkalakal, J; Dirksen, RT; Elfar, JC; Gurjar, A; Lee, JI; Noble, M; Talukder, MAH; Yue, L, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Govindappa, PK | 1 |
| Jagadeeshaprasad, MG | 1 |
| Tortora, P | 1 |
| Talukder, MAH | 2 |
| Elfar, JC | 2 |
| Yue, L | 1 |
| Gurjar, A | 1 |
| Lee, JI | 1 |
| Noble, M | 1 |
| Dirksen, RT | 1 |
| Chakkalakal, J | 1 |
| Morbiato, L | 1 |
| Carli, L | 1 |
| Johnson, EA | 1 |
| Montecucco, C | 1 |
| Molgó, J | 1 |
| Rossetto, O | 1 |
3 other studies available for 4-aminopyridine and Muscular Atrophy
| Article | Year |
|---|---|
Effects of 4-Aminopyridine on Combined Nerve and Muscle Injury and Bone Loss.
Topics: 4-Aminopyridine; Animals; Bone Diseases, Metabolic; Mice; Muscles; Muscular Atrophy; Nerve Regenerat | 2023 |
4-Aminopyridine attenuates muscle atrophy after sciatic nerve crush injury in mice.
Topics: 4-Aminopyridine; Animals; Crush Injuries; Forkhead Box Protein O1; Forkhead Box Protein O3; Mice; Mu | 2019 |
Neuromuscular paralysis and recovery in mice injected with botulinum neurotoxins A and C.
Topics: 4-Aminopyridine; Amifampridine; Animals; Botulinum Toxins; Botulinum Toxins, Type A; Drug Resistance | 2007 |