4-aminopyridine has been researched along with Long QT Syndrome in 4 studies
Long QT Syndrome: A condition that is characterized by episodes of fainting (SYNCOPE) and varying degree of ventricular arrhythmia as indicated by the prolonged QT interval. The inherited forms are caused by mutation of genes encoding cardiac ion channel proteins. The two major forms are ROMANO-WARD SYNDROME and JERVELL-LANGE NIELSEN SYNDROME.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Spontaneous and stimulation-induced polymorphic ventricular tachycardia with characteristics of torsade de pointes (TdP) developed in the presence of dl-sotalol." | 3.70 | Cellular basis for the normal T wave and the electrocardiographic manifestations of the long-QT syndrome. ( Antzelevitch, C; Yan, GX, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (50.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Brunner, M | 1 |
| Kodirov, SA | 1 |
| Mitchell, GF | 2 |
| Buckett, PD | 1 |
| Shibata, K | 1 |
| Folco, EJ | 1 |
| Baker, L | 1 |
| Salama, G | 1 |
| Chan, DP | 1 |
| Zhou, J | 2 |
| Koren, G | 2 |
| Nerbonne, JM | 1 |
| London, B | 1 |
| Jeron, A | 1 |
| Buckett, P | 1 |
| Han, X | 1 |
| Yan, GX | 1 |
| Antzelevitch, C | 1 |
1 review available for 4-aminopyridine and Long QT Syndrome
| Article | Year |
|---|---|
Studying cardiac arrhythmias in the mouse--a reasonable model for probing mechanisms?
Topics: 4-Aminopyridine; Action Potentials; Animals; Arrhythmias, Cardiac; Disease Models, Animal; ERG1 Pota | 2004 |
3 other studies available for 4-aminopyridine and Long QT Syndrome
| Article | Year |
|---|---|
In vivo gene transfer of Kv1.5 normalizes action potential duration and shortens QT interval in mice with long QT phenotype.
Topics: 4-Aminopyridine; Action Potentials; Adenoviridae; Animals; Blotting, Western; Cells, Cultured; Cloni | 2003 |
Long QT and ventricular arrhythmias in transgenic mice expressing the N terminus and first transmembrane segment of a voltage-gated potassium channel.
Topics: 4-Aminopyridine; Animals; Biological Transport; Electric Conductivity; Electrophysiology; Endoplasmi | 1998 |
Cellular basis for the normal T wave and the electrocardiographic manifestations of the long-QT syndrome.
Topics: 4-Aminopyridine; Action Potentials; Animals; Anti-Arrhythmia Agents; Dogs; Electrocardiography; Endo | 1998 |