4-aminopyridine has been researched along with Glioma in 9 studies
Glioma: Benign and malignant central nervous system neoplasms derived from glial cells (i.e., astrocytes, oligodendrocytes, and ependymocytes). Astrocytes may give rise to astrocytomas (ASTROCYTOMA) or glioblastoma multiforme (see GLIOBLASTOMA). Oligodendrocytes give rise to oligodendrogliomas (OLIGODENDROGLIOMA) and ependymocytes may undergo transformation to become EPENDYMOMA; CHOROID PLEXUS NEOPLASMS; or colloid cysts of the third ventricle. (From Escourolle et al., Manual of Basic Neuropathology, 2nd ed, p21)
| Excerpt | Relevance | Reference |
|---|---|---|
| " Our previous study proved that the Kv channel blocker 4-aminopyridine (4-AP) could inhibit cell proliferation and induce apoptosis in glioma." | 7.88 | Voltage-gated potassium channel blocker 4-aminopyridine induces glioma cell apoptosis by reducing expression of microRNA-10b-5p. ( Chen, L; Li, CY; Li, WL; Ru, Q; Tian, X; Xiong, Q, 2018) |
| " Our previous study proved that the Kv channel blocker 4-aminopyridine (4-AP) could inhibit cell proliferation and induce apoptosis in glioma." | 3.88 | Voltage-gated potassium channel blocker 4-aminopyridine induces glioma cell apoptosis by reducing expression of microRNA-10b-5p. ( Chen, L; Li, CY; Li, WL; Ru, Q; Tian, X; Xiong, Q, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (22.22) | 18.7374 |
| 1990's | 4 (44.44) | 18.2507 |
| 2000's | 1 (11.11) | 29.6817 |
| 2010's | 2 (22.22) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ru, Q | 2 |
| Li, WL | 1 |
| Xiong, Q | 1 |
| Chen, L | 1 |
| Tian, X | 2 |
| Li, CY | 2 |
| Wu, YX | 1 |
| Wu, RH | 1 |
| Pi, MS | 1 |
| Zakir Hossain, SM | 1 |
| Shinohara, H | 1 |
| Kitano, H | 1 |
| Hu, Q | 2 |
| Shi, YL | 1 |
| Huang, F | 1 |
| Shi, Y | 1 |
| Rouzaire-Dubois, B | 1 |
| Dubois, JM | 1 |
| Robbins, J | 1 |
| Sim, JA | 1 |
| Brismar, T | 2 |
| Collins, VP | 2 |
9 other studies available for 4-aminopyridine and Glioma
| Article | Year |
|---|---|
Voltage-gated potassium channel blocker 4-aminopyridine induces glioma cell apoptosis by reducing expression of microRNA-10b-5p.
Topics: 4-Aminopyridine; Apoptosis; Apoptosis Regulatory Proteins; Apoptotic Protease-Activating Factor 1; C | 2018 |
Voltage-gated and ATP-sensitive K+ channels are associated with cell proliferation and tumorigenesis of human glioma.
Topics: 4-Aminopyridine; Animals; Apoptosis; Calcium; Calcium Signaling; Cell Line, Tumor; Cell Proliferatio | 2014 |
Drug assessment based on detection of L-glutamate released from C6 glioma cells using an enzyme-luminescence method.
Topics: 4-Aminopyridine; Animals; Brain Neoplasms; Carbamazepine; Cell Line, Tumor; Enzymes; Flunarizine; Gl | 2008 |
Characterization of an inward-rectifying potassium current in NG108-15 neuroblastoma x glioma cells.
Topics: 4-Aminopyridine; Barium; Bucladesine; Cadmium; Calcium; Cell Differentiation; Cesium; Cobalt; Cyclic | 1997 |
Inhibition of Toosendanin on the delayed rectifier potassium current in neuroblastoma x glioma NG108-15 cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1997 |
Modification of electrophysiological and pharmacological properties of K channels in neuroblastoma cells induced by the oxidant chloramine-T.
Topics: 4-Aminopyridine; Animals; Calcium Channels; Chloramines; Electrophysiology; Glioma; Hybrid Cells; Io | 1990 |
A transient outward current in NG108-15 neuroblastoma x glioma hybrid cells.
Topics: 4-Aminopyridine; Action Potentials; Adrenergic Fibers; Animals; Barium; Calcium; Elapid Venoms; Glio | 1990 |
Inward rectifying potassium channels in human malignant glioma cells.
Topics: 4-Aminopyridine; Aminopyridines; Cell Line; Glioma; Humans; Ion Channels; Membrane Potentials; Potas | 1989 |
Potassium and sodium channels in human malignant glioma cells.
Topics: 4-Aminopyridine; Aminopyridines; Calcium; Cell Line; Glioma; Humans; Ion Channels; Potassium; Sodium | 1989 |