4-aminopyridine has been researched along with Epilepsy, Absence in 8 studies
Epilepsy, Absence: A seizure disorder usually occurring in childhood characterized by rhythmic electrical brain discharges of generalized onset. Clinical features include a sudden cessation of ongoing activity usually without loss of postural tone. Rhythmic blinking of the eyelids or lip smacking frequently accompanies the SEIZURES. The usual duration is 5-10 seconds, and multiple episodes may occur daily. Juvenile absence epilepsy is characterized by the juvenile onset of absence seizures and an increased incidence of myoclonus and tonic-clonic seizures. (Menkes, Textbook of Child Neurology, 5th ed, p736)
| Excerpt | Relevance | Reference |
|---|---|---|
| " We compared the epileptiform activities induced by 4-aminopyridine (4-AP) induced in hippocampal-entorhinal cortex slices from genetic absence epilepsy rats of Strasbourg (GAERS, age 6 months) in which absence seizures have been present for about 4 months and from control non epileptic rats (NE)." | 3.70 | Epileptiform activity induced by 4-aminopyridine in entorhinal cortex hippocampal slices of rats with a genetically determined absence epilepsy (GAERS). ( Armand, V; Heinemann, U; Hoffmann, P; Vergnes, M, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (25.00) | 18.2507 |
| 2000's | 6 (75.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Inaba, Y | 1 |
| D'Antuono, M | 4 |
| Bertazzoni, G | 1 |
| Biagini, G | 3 |
| Avoli, M | 4 |
| D'Arcangelo, G | 2 |
| Warren, R | 1 |
| Tancredi, V | 3 |
| Strupp, M | 1 |
| Kalla, R | 1 |
| Freilinger, T | 1 |
| Dichgans, M | 1 |
| Brandt, T | 1 |
| Gigout, S | 1 |
| Louvel, J | 2 |
| Pumain, R | 2 |
| Mihály, A | 1 |
| Szente, M | 1 |
| Dobo, E | 1 |
| Pór, I | 1 |
| Armand, V | 1 |
| Hoffmann, P | 1 |
| Vergnes, M | 1 |
| Heinemann, U | 1 |
8 other studies available for 4-aminopyridine and Epilepsy, Absence
| Article | Year |
|---|---|
Diminished presynaptic GABA(B) receptor function in the neocortex of a genetic model of absence epilepsy.
Topics: 4-Aminopyridine; Animals; Baclofen; Cell Membrane; Disease Models, Animal; Dose-Response Relationshi | 2009 |
Thalamocortical oscillations in a genetic model of absence seizures.
Topics: 4-Aminopyridine; Action Potentials; Animals; Biological Clocks; Cerebral Cortex; Disease Models, Ani | 2002 |
Dysfunction of the brain calcium channel CaV2.1 in absence epilepsy and episodic ataxia--a comment.
Topics: 4-Aminopyridine; Adult; Calcium Channels, N-Type; Cerebellar Ataxia; Epilepsy, Absence; Female; Huma | 2005 |
Effects in vitro and in vivo of a gap junction blocker on epileptiform activities in a genetic model of absence epilepsy.
Topics: 4-Aminopyridine; Animals; Anticonvulsants; Carbenoxolone; Cerebral Cortex; Disease Models, Animal; E | 2006 |
Neocortical hyperexcitability in a genetic model of absence seizures and its reduction by levetiracetam.
Topics: 4-Aminopyridine; Age Factors; Animals; Anticonvulsants; Disease Models, Animal; Electric Stimulation | 2006 |
Early activation of inhibitory neurons in the thalamic reticular nucleus during focal neocortical seizures.
Topics: 4-Aminopyridine; Animals; Cell Count; Electroencephalography; Epilepsy, Absence; Geniculate Bodies; | 1998 |
Epileptiform activity induced by 4-aminopyridine in entorhinal cortex hippocampal slices of rats with a genetically determined absence epilepsy (GAERS).
Topics: 4-Aminopyridine; Animals; Entorhinal Cortex; Epilepsy, Absence; Evoked Potentials; Hippocampus; In V | 1999 |
Spindle-like thalamocortical synchronization in a rat brain slice preparation.
Topics: 4-Aminopyridine; Animals; Barbiturates; Cerebral Cortex; Cortical Synchronization; Electric Stimulat | 2000 |