4-aminopyridine has been researched along with Epilepsies, Partial in 10 studies
Epilepsies, Partial: Conditions characterized by recurrent paroxysmal neuronal discharges which arise from a focal region of the brain. Partial seizures are divided into simple and complex, depending on whether consciousness is unaltered (simple partial seizure) or disturbed (complex partial seizure). Both types may feature a wide variety of motor, sensory, and autonomic symptoms. Partial seizures may be classified by associated clinical features or anatomic location of the seizure focus. A secondary generalized seizure refers to a partial seizure that spreads to involve the brain diffusely. (From Adams et al., Principles of Neurology, 6th ed, pp317)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Focal neocortical seizures, induced by injection of 4-aminopyridine, were imaged in the rat neocortex using the intrinsic optical signal, with incident light at various wavelengths." | 3.73 | Intrinsic optical signal imaging of neocortical seizures: the 'epileptic dip'. ( Bahar, S; Schwartz, TH; Suh, M; Zhao, M, 2006) |
| "Because our seizure model is very severe, it is probable that this technique would have a robust effect in human focal epilepsy." | 1.36 | Optical suppression of experimental seizures in rat brain slices. ( Rode, DL; Rothman, SM; Schmidt, BF; Yang, XF, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (30.00) | 18.2507 |
| 2000's | 6 (60.00) | 29.6817 |
| 2010's | 1 (10.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Panuccio, G | 1 |
| Curia, G | 1 |
| Colosimo, A | 1 |
| Cruccu, G | 1 |
| Avoli, M | 5 |
| Yang, XF | 1 |
| Schmidt, BF | 1 |
| Rode, DL | 1 |
| Rothman, SM | 1 |
| Barbarosie, M | 1 |
| Louvel, J | 2 |
| D'Antuono, M | 2 |
| Kurcewicz, I | 1 |
| Köhling, R | 1 |
| Mattia, D | 3 |
| Bernasconi, A | 2 |
| Olivier, A | 3 |
| Turak, B | 1 |
| Devaux, A | 1 |
| Pumain, R | 1 |
| Bracci, E | 1 |
| Centonze, D | 1 |
| Bernardi, G | 1 |
| Calabresi, P | 1 |
| Bahar, S | 1 |
| Suh, M | 1 |
| Zhao, M | 1 |
| Schwartz, TH | 1 |
| Karpova, MN | 1 |
| Pankov, OIu | 1 |
| Germane, SK | 1 |
| Klusha, VE | 1 |
| Duburs, G | 1 |
| Hwa, GG | 1 |
| Brückner, C | 1 |
| Heinemann, U | 1 |
10 other studies available for 4-aminopyridine and Epilepsies, Partial
| Article | Year |
|---|---|
Epileptiform synchronization in the cingulate cortex.
Topics: 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Anticonvulsants; Cortical Synchroniz | 2009 |
Optical suppression of experimental seizures in rat brain slices.
Topics: 4-Aminopyridine; Animals; Convulsants; Disease Models, Animal; Epilepsies, Partial; GABA Agents; gam | 2010 |
Masking synchronous GABA-mediated potentials controls limbic seizures.
Topics: 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Culture Techniques; Electroencephalo | 2002 |
GABAA receptor-dependent synchronization leads to ictogenesis in the human dysplastic cortex.
Topics: 4-Aminopyridine; Adolescent; Adult; Analysis of Variance; Baclofen; Child; Electrophysiology; Epilep | 2004 |
Engagement of rat striatal neurons by cortical epileptiform activity investigated with paired recordings.
Topics: 4-Aminopyridine; Animals; Bicuculline; Cerebral Cortex; Corpus Striatum; Epilepsies, Partial; Male; | 2004 |
Intrinsic optical signal imaging of neocortical seizures: the 'epileptic dip'.
Topics: 4-Aminopyridine; Animals; Data Interpretation, Statistical; Electrophysiology; Epilepsies, Partial; | 2006 |
Seizure-like discharges recorded in human dysplastic neocortex maintained in vitro.
Topics: 4-Aminopyridine; Action Potentials; Cells, Cultured; Cerebral Cortex; Epilepsies, Partial; Humans | 1995 |
[The antiepileptic effects of the combined action of the new 1,4-dihydropyridine derivative glutapyrone with sodium valproate and phenobarbital].
Topics: 4-Aminopyridine; Animals; Anticonvulsants; Dihydropyridines; Drug Evaluation, Preclinical; Drug Ther | 1993 |
Epileptiform discharges in the human dysplastic neocortex: in vitro physiology and pharmacology.
Topics: 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Adolescent; Adult; Anticonvulsants; Cerebral | 1999 |
Effects of standard anticonvulsant drugs on different patterns of epileptiform discharges induced by 4-aminopyridine in combined entorhinal cortex-hippocampal slices.
Topics: 4-Aminopyridine; Animals; Anticonvulsants; Carbamazepine; Entorhinal Cortex; Epilepsies, Partial; Fe | 2000 |