4-aminopyridine has been researched along with Dystonia in 2 studies
Dystonia: An attitude or posture due to the co-contraction of agonists and antagonist muscles in one region of the body. It most often affects the large axial muscles of the trunk and limb girdles. Conditions which feature persistent or recurrent episodes of dystonia as a primary manifestation of disease are referred to as DYSTONIC DISORDERS. (Adams et al., Principles of Neurology, 6th ed, p77)
| Excerpt | Relevance | Reference |
|---|---|---|
| "4-Aminopyridine (4-AP) is an investigational drug for the treatment of neurologic disorders including multiple sclerosis (MS)." | 3.69 | Atypical presentation of 4-aminopyridine overdose. ( Enns, R; Pickett, TA, 1996) |
| "AMPA receptor agonists induced dystonia, and AMPA receptor antagonists reduced the dystonia induced by glutamate receptor agonists." | 1.38 | Selective and sustained α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor activation in cerebellum induces dystonia in mice. ( Fan, X; Hess, EJ; Hughes, KE; Jinnah, HA, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fan, X | 1 |
| Hughes, KE | 1 |
| Jinnah, HA | 1 |
| Hess, EJ | 1 |
| Pickett, TA | 1 |
| Enns, R | 1 |
2 other studies available for 4-aminopyridine and Dystonia
| Article | Year |
|---|---|
Selective and sustained α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor activation in cerebellum induces dystonia in mice.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 2012 |
Atypical presentation of 4-aminopyridine overdose.
Topics: 4-Aminopyridine; Adult; Drug Overdose; Dystonia; Female; Humans; Multiple Sclerosis | 1996 |