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4-aminopyridine and Degenerative Diseases, Central Nervous System

4-aminopyridine has been researched along with Degenerative Diseases, Central Nervous System in 5 studies

Research Excerpts

ExcerptRelevanceReference
"The voltage-gated K(+) (Kv) channel blocker 4-aminopyridine (4-AP) is used to target symptoms of the neuroinflammatory disease multiple sclerosis (MS)."7.79Inhibition of neuronal degenerin/epithelial Na+ channels by the multiple sclerosis drug 4-aminopyridine. ( Boiko, N; Eaton, BA; Kucher, V; Stockand, JD, 2013)
"The voltage-gated K(+) (Kv) channel blocker 4-aminopyridine (4-AP) is used to target symptoms of the neuroinflammatory disease multiple sclerosis (MS)."3.79Inhibition of neuronal degenerin/epithelial Na+ channels by the multiple sclerosis drug 4-aminopyridine. ( Boiko, N; Eaton, BA; Kucher, V; Stockand, JD, 2013)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (60.00)29.6817
2010's2 (40.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Boiko, N1
Kucher, V1
Eaton, BA1
Stockand, JD1
Ayala, GX1
Tapia, R2
Flynn, JM1
Choi, SW1
Day, NU1
Gerencser, AA1
Hubbard, A1
Melov, S1
Tebano, MT1
Pintor, A1
Frank, C1
Domenici, MR1
Martire, A1
Pepponi, R1
Potenza, RL1
Grieco, R1
Popoli, P1
Mora, G1

Other Studies

5 other studies available for 4-aminopyridine and Degenerative Diseases, Central Nervous System

ArticleYear
Inhibition of neuronal degenerin/epithelial Na+ channels by the multiple sclerosis drug 4-aminopyridine.
    The Journal of biological chemistry, 2013, Mar-29, Volume: 288, Issue:13

    Topics: 4-Aminopyridine; Animals; Animals, Newborn; CHO Cells; Cricetinae; Degenerin Sodium Channels; Drosop

2013
HSP70 expression protects against hippocampal neurodegeneration induced by endogenous glutamate in vivo.
    Neuropharmacology, 2008, Volume: 55, Issue:8

    Topics: 4-Aminopyridine; Animals; Cell Count; Disease Models, Animal; Dizocilpine Maleate; Electroencephalog

2008
Impaired spare respiratory capacity in cortical synaptosomes from Sod2 null mice.
    Free radical biology & medicine, 2011, Apr-01, Volume: 50, Issue:7

    Topics: 4-Aminopyridine; Animals; Biomimetics; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Cerebral

2011
Adenosine A2A receptor blockade differentially influences excitotoxic mechanisms at pre- and postsynaptic sites in the rat striatum.
    Journal of neuroscience research, 2004, Jul-01, Volume: 77, Issue:1

    Topics: 4-Aminopyridine; Adenosine; Adenosine A2 Receptor Antagonists; Animals; Calcium; Corpus Striatum; Do

2004
Effects of retigabine on the neurodegeneration and extracellular glutamate changes induced by 4-aminopyridine in rat hippocampus in vivo.
    Neurochemical research, 2005, Volume: 30, Issue:12

    Topics: 4-Aminopyridine; Animals; Anticonvulsants; Carbamates; Drug Interactions; Electroencephalography; Ex

2005