4-aminopyridine has been researched along with Brain Injuries in 3 studies
Brain Injuries: Acute and chronic (see also BRAIN INJURIES, CHRONIC) injuries to the brain, including the cerebral hemispheres, CEREBELLUM, and BRAIN STEM. Clinical manifestations depend on the nature of injury. Diffuse trauma to the brain is frequently associated with DIFFUSE AXONAL INJURY or COMA, POST-TRAUMATIC. Localized injuries may be associated with NEUROBEHAVIORAL MANIFESTATIONS; HEMIPARESIS, or other focal neurologic deficits.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Acquired brain injury can cause eye movement disorders which may include: strabismus, gaze deficits and nystagmus, causing visual symptoms of double, blurred or 'juddery' vision and reading difficulties." | 2.58 | Interventions for eye movement disorders due to acquired brain injury. ( Dodridge, CS; Evans, JR; Garcia-Finana, M; Hanna, K; Howard, C; Jarvis, KA; Maan, T; MacDiarmid, SL; Noonan, CP; North, L; Rodgers, H; Rowe, FJ, 2018) |
| "Thus, reactive gliosis and a significant increase in the expression of caspase-9 were found in the aforementioned brain area." | 1.46 | Subacute Fluoxetine Reduces Signs of Hippocampal Damage Induced by a Single Convulsant Dose of 4-Aminopyridine in Rats. ( de la Rosa, RF; Delgado, M; García-García, L; Pozo, MA; Shiha, AA, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rowe, FJ | 1 |
| Hanna, K | 1 |
| Evans, JR | 1 |
| Noonan, CP | 1 |
| Garcia-Finana, M | 1 |
| Dodridge, CS | 1 |
| Howard, C | 1 |
| Jarvis, KA | 1 |
| MacDiarmid, SL | 1 |
| Maan, T | 1 |
| North, L | 1 |
| Rodgers, H | 1 |
| Goddeyne, C | 1 |
| Nichols, J | 1 |
| Wu, C | 1 |
| Anderson, T | 1 |
| Shiha, AA | 1 |
| de la Rosa, RF | 1 |
| Delgado, M | 1 |
| Pozo, MA | 1 |
| García-García, L | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Examining the Effect of Eye Gaze Technology on Children With Cortical Visual Impairment and Its Impact on Occupational Performance[NCT06067607] | 10 participants (Anticipated) | Interventional | 2023-02-01 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for 4-aminopyridine and Brain Injuries
| Article | Year |
|---|---|
Interventions for eye movement disorders due to acquired brain injury.
Topics: 4-Aminopyridine; Abducens Nerve Diseases; Amifampridine; Amines; Baclofen; Botulinum Toxins; Brain I | 2018 |
2 other studies available for 4-aminopyridine and Brain Injuries
| Article | Year |
|---|---|
Repetitive mild traumatic brain injury induces ventriculomegaly and cortical thinning in juvenile rats.
Topics: 4-Aminopyridine; Action Potentials; Animals; Animals, Newborn; Body Weight; Brain Injuries; Cerebral | 2015 |
Subacute Fluoxetine Reduces Signs of Hippocampal Damage Induced by a Single Convulsant Dose of 4-Aminopyridine in Rats.
Topics: 4-Aminopyridine; Animals; Brain Injuries; Caspase 9; Cell Death; Convulsants; Disease Models, Animal | 2017 |