4-aminopyridine has been researched along with Blood Pressure, High in 18 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| " Diminished PAME release and its vasorelaxing activity and increased release of angiotensin II in the PVAT suggest a noble role of PVAT in pathogenesis of hypertension." | 7.77 | Role of perivascular adipose tissue-derived methyl palmitate in vascular tone regulation and pathogenesis of hypertension. ( Chang, HH; Chen, MF; Chen, PY; Chiang, CL; Kuo, JS; Lee, TJ; Lee, YC; Liu, CH; Yeh, JI, 2011) |
| " Diminished PAME release and its vasorelaxing activity and increased release of angiotensin II in the PVAT suggest a noble role of PVAT in pathogenesis of hypertension." | 3.77 | Role of perivascular adipose tissue-derived methyl palmitate in vascular tone regulation and pathogenesis of hypertension. ( Chang, HH; Chen, MF; Chen, PY; Chiang, CL; Kuo, JS; Lee, TJ; Lee, YC; Liu, CH; Yeh, JI, 2011) |
| "This study was designed to investigate involvement of potassium channels in the action of nitric oxide facilitating reduction of basal tone by thromboxane A2/prostaglandin H2 receptor blockade with ifetroban in rings of thoracic aorta taken from rats with aortic coarctation-induced hypertension." | 3.70 | Involvement of nitric oxide and potassium channels in the reduction of basal tone produced by blockade of thromboxane A2/prostaglandin H2 receptors in aortic rings of hypertensive rats. ( DelliPizzi, A; Nasjletti, A, 1998) |
| " We tested the effects of inhibitors of calcium-dependent K(+) channels [iberiotoxin (50 nM) and tetraethylammonium (TEA, 1 mM)] on changes in arteriolar diameter during acute hypertension." | 3.70 | Potassium channels modulate cerebral autoregulation during acute hypertension. ( Faraci, FM; Heistad, DD; Paternò, R, 2000) |
| "Nitroxyl anion (HNO) has recently become an emerging candidate in vascular regulation." | 1.46 | Nitroxyl Anion Mediates Relaxation in Mesenteric Arteries from Angiotensin II Hypertensive Mice. ( Labazi, H; Tostes, RC; Webb, RC; Wynne, BM, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 9 (50.00) | 18.2507 |
| 2000's | 7 (38.89) | 29.6817 |
| 2010's | 2 (11.11) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wynne, BM | 1 |
| Labazi, H | 1 |
| Tostes, RC | 1 |
| Webb, RC | 2 |
| Gálvez-Prieto, B | 1 |
| Dubrovska, G | 2 |
| Cano, MV | 1 |
| Delgado, M | 1 |
| Aranguez, I | 2 |
| González, MC | 2 |
| Ruiz-Gayo, M | 1 |
| Gollasch, M | 2 |
| Fernández-Alfonso, MS | 1 |
| Badruddin, A | 1 |
| Menon, RS | 1 |
| Reder, AT | 1 |
| Lee, YC | 1 |
| Chang, HH | 1 |
| Chiang, CL | 1 |
| Liu, CH | 1 |
| Yeh, JI | 1 |
| Chen, MF | 1 |
| Chen, PY | 1 |
| Kuo, JS | 1 |
| Lee, TJ | 1 |
| Sadanaga, T | 1 |
| Ohya, Y | 1 |
| Ohtsubo, T | 1 |
| Goto, K | 1 |
| Fujii, K | 1 |
| Abe, I | 1 |
| Berg, T | 1 |
| Kubo, T | 1 |
| Hagiwara, Y | 1 |
| Gálvez, B | 1 |
| de Castro, J | 1 |
| Herold, D | 1 |
| Arribas, S | 1 |
| Luft, FC | 1 |
| Ramos, MP | 1 |
| Fernández Alfonso, MS | 1 |
| Chapleau, MW | 1 |
| Abboud, FM | 1 |
| Hendriks, MG | 1 |
| Pfaffendorf, M | 1 |
| van Zwieten, PA | 1 |
| Takemoto, T | 1 |
| Eda, M | 1 |
| Okada, T | 1 |
| Sakashita, H | 1 |
| Matzno, S | 1 |
| Gohda, M | 1 |
| Ebisu, H | 1 |
| Nakamura, N | 1 |
| Fukaya, C | 1 |
| Hihara, M | 1 |
| Kolias, TJ | 1 |
| Chai, S | 1 |
| Cox, RH | 1 |
| Hohage, H | 1 |
| Hess, K | 1 |
| Jahl, C | 1 |
| Greven, J | 1 |
| Schlatter, E | 1 |
| DelliPizzi, A | 1 |
| Nasjletti, A | 1 |
| Nand, V | 1 |
| Doggrell, SA | 1 |
| Honda, H | 1 |
| Unemoto, T | 1 |
| Kogo, H | 1 |
| Paternò, R | 1 |
| Heistad, DD | 1 |
| Faraci, FM | 1 |
1 review available for 4-aminopyridine and Blood Pressure, High
| Article | Year |
|---|---|
Modulation of baroreceptor activity by ionic and paracrine mechanisms: an overview.
Topics: 4-Aminopyridine; Animals; Arteriosclerosis; Blood Pressure; Carotid Sinus; Endothelium, Vascular; Hu | 1994 |
17 other studies available for 4-aminopyridine and Blood Pressure, High
| Article | Year |
|---|---|
Nitroxyl Anion Mediates Relaxation in Mesenteric Arteries from Angiotensin II Hypertensive Mice.
Topics: 4-Aminopyridine; Acetylcholine; Angiotensin II; Animals; Disease Models, Animal; Hypertension; Male; | 2017 |
A reduction in the amount and anti-contractile effect of periadventitial mesenteric adipose tissue precedes hypertension development in spontaneously hypertensive rats.
Topics: 4-Aminopyridine; Adipose Tissue; Animals; Hypertension; Male; Mesenteric Arteries; Nitric Oxide; Nor | 2008 |
4-Aminopyridine toxicity mimics autoimmune-mediated limbic encephalitis.
Topics: 4-Aminopyridine; Diagnosis, Differential; Diagnostic Errors; Drug Overdose; Echocardiography; Electr | 2009 |
Role of perivascular adipose tissue-derived methyl palmitate in vascular tone regulation and pathogenesis of hypertension.
Topics: 4-Aminopyridine; Adipocytes; Adipose Tissue; Angiotensin II; Animals; Aorta; Calcium; Cells, Culture | 2011 |
Decreased 4-aminopyridine sensitive K+ currents in endothelial cells from hypertensive rats.
Topics: 4-Aminopyridine; Animals; Aorta; Apamin; Charybdotoxin; Drug Combinations; Endothelium, Vascular; Ge | 2002 |
The vascular response to the K+ channel inhibitor 4-aminopyridine in hypertensive rats.
Topics: 4-Aminopyridine; Adrenalectomy; Adrenergic Antagonists; Amifampridine; Angiotensin Receptor Antagoni | 2003 |
Protein kinase C activation-induced increases of neural activity are enhanced in the hypothalamus of spontaneously hypertensive rats.
Topics: 4-Aminopyridine; Action Potentials; Angiotensin II; Animals; Dose-Response Relationship, Drug; Enzym | 2005 |
Perivascular adipose tissue and mesenteric vascular function in spontaneously hypertensive rats.
Topics: 4-Aminopyridine; Adipocytes; Adipose Tissue; Animals; Blood Vessels; Cell Size; Hypertension; In Vit | 2006 |
The role of nitric oxide and potassium channels in endothelium-dependent vasodilation in SHR.
Topics: 4-Aminopyridine; Animals; Arginine; Biological Factors; Endothelium, Vascular; Hypertension; In Vitr | 1993 |
Novel potassium channel openers: synthesis and pharmacological evaluation of new N-(substituted-3-pyridyl)-N'-alkylthioureas and related compounds.
Topics: 4-Aminopyridine; Amifampridine; Animals; Antihypertensive Agents; Biomechanical Phenomena; Glyburide | 1994 |
Potassium channel antagonists and vascular reactivity in stroke-prone spontaneously hypertensive rats.
Topics: 4-Aminopyridine; Amifampridine; Animals; Apamin; Barium; Cardiovascular System; Carotid Arteries; Ce | 1993 |
Comparison of K+ channel properties in freshly isolated myocytes from thoracic aorta of WKY and SHR.
Topics: 4-Aminopyridine; Animals; Aorta, Thoracic; Hypertension; In Vitro Techniques; Male; Muscle Fibers, S | 1996 |
Renal and blood pressure effects of moxonidine and clonidine in spontaneously hypertensive rats.
Topics: 4-Aminopyridine; Adrenergic alpha-Antagonists; Aminoacridines; Angiotensin Receptor Antagonists; Ani | 1997 |
Involvement of nitric oxide and potassium channels in the reduction of basal tone produced by blockade of thromboxane A2/prostaglandin H2 receptors in aortic rings of hypertensive rats.
Topics: 4-Aminopyridine; Animals; Aorta; Basal Metabolism; Bridged Bicyclo Compounds, Heterocyclic; Hyperten | 1998 |
Effects of tetraethylammonium, 4-aminopyridine and bretylium on cardiovascular tissues from normo- and hypertensive rats.
Topics: 4-Aminopyridine; Action Potentials; Animals; Arteries; Bretylium Compounds; Cardiovascular System; H | 1999 |
Different mechanisms for testosterone-induced relaxation of aorta between normotensive and spontaneously hypertensive rats.
Topics: 4-Aminopyridine; Acetylcholine; Animals; Aorta, Thoracic; Cyclooxygenase Inhibitors; Dose-Response R | 1999 |
Potassium channels modulate cerebral autoregulation during acute hypertension.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 4-Aminopyridine; Acute Disease; | 2000 |