4-aminopyridine has been researched along with Benign Psychomotor Epilepsy, Childhood in 24 studies
Excerpt | Relevance | Reference |
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" In this study we used the pilocarpine-induced status epilepticus model of TLE (i." | 3.91 | Altered A-type potassium channel function in the nucleus tractus solitarii in acquired temporal lobe epilepsy. ( Derera, ID; Smith, BN; Smith, KC, 2019) |
"Limbic seizures can be mimicked in vitro using preparations of combined hippocampus-entorhinal cortex slices perfused with artificial cerebrospinal fluid containing convulsants or nominally zero Mg(2+), in order to produce epileptiform synchronization." | 2.41 | Network and pharmacological mechanisms leading to epileptiform synchronization in the limbic system in vitro. ( Avoli, M; Biagini, G; D'Antuono, M; D'Arcangelo, G; Köhling, R; Louvel, J; Pumain, R; Tancredi, V, 2002) |
"To investigate the abortion of seizure generation using "minimal" intervention in hippocampi using two rat models of human temporal lobe epilepsy." | 1.42 | Rapid brief feedback intracerebral stimulation based on real-time desynchronization detection preceding seizures stops the generation of convulsive paroxysms. ( Genov, R; Kassiri, H; Perez Velazquez, JL; Salam, MT, 2015) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 3 (12.50) | 18.2507 |
2000's | 10 (41.67) | 29.6817 |
2010's | 9 (37.50) | 24.3611 |
2020's | 2 (8.33) | 2.80 |
Authors | Studies |
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Scalmani, P | 1 |
Paterra, R | 1 |
Mantegazza, M | 1 |
Avoli, M | 11 |
de Curtis, M | 1 |
Kong, S | 1 |
Chen, TX | 1 |
Jia, XL | 1 |
Cheng, XL | 1 |
Zeng, ML | 1 |
Liang, JY | 1 |
He, XH | 1 |
Yin, J | 1 |
Han, S | 1 |
Liu, WH | 1 |
Fan, YT | 1 |
Zhou, T | 1 |
Liu, YM | 1 |
Peng, BW | 1 |
Derera, ID | 1 |
Smith, KC | 1 |
Smith, BN | 1 |
Lévesque, M | 1 |
Salami, P | 1 |
Behr, C | 1 |
Tang, Y | 1 |
Durand, DM | 2 |
Grosser, S | 1 |
Queenan, BN | 1 |
Lalchandani, RR | 1 |
Vicini, S | 1 |
Salam, MT | 1 |
Kassiri, H | 1 |
Genov, R | 1 |
Perez Velazquez, JL | 1 |
Ahn, S | 1 |
Jun, SB | 1 |
Lee, HW | 1 |
Lee, S | 1 |
Panuccio, G | 1 |
D'Antuono, M | 5 |
de Guzman, P | 1 |
De Lannoy, L | 1 |
Biagini, G | 3 |
Jung, S | 1 |
Yang, H | 1 |
Kim, BS | 1 |
Chu, K | 1 |
Lee, SK | 1 |
Jeon, D | 1 |
Toprani, S | 1 |
Moe, MC | 1 |
Berg-Johnsen, J | 2 |
Larsen, GA | 1 |
Røste, GK | 2 |
Vinje, ML | 2 |
Louvel, J | 3 |
Köhling, R | 2 |
Pumain, R | 3 |
D'Arcangelo, G | 3 |
Tancredi, V | 3 |
Niittykoski, M | 1 |
Nissinen, J | 1 |
Penttonen, M | 1 |
Pitkänen, A | 1 |
Mattia, D | 2 |
Bernasconi, A | 2 |
Olivier, A | 3 |
Turak, B | 2 |
Devaux, A | 1 |
Bernard, C | 1 |
Anderson, A | 1 |
Becker, A | 1 |
Poolos, NP | 1 |
Beck, H | 1 |
Johnston, D | 1 |
Gigout, S | 1 |
Kawasaki, H | 1 |
Armand, V | 1 |
Kurcewicz, I | 1 |
Laschet, J | 1 |
Devaux, B | 1 |
Sudbury, JR | 1 |
Barbarosie, M | 2 |
Valø, ET | 1 |
Hwa, GG | 1 |
Ohno, K | 1 |
Higashima, M | 1 |
Benini, R | 1 |
1 review available for 4-aminopyridine and Benign Psychomotor Epilepsy, Childhood
Article | Year |
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Network and pharmacological mechanisms leading to epileptiform synchronization in the limbic system in vitro.
Topics: 4-Aminopyridine; Action Potentials; Animals; Electric Stimulation; Electrophysiology; Entorhinal Cor | 2002 |
1 trial available for 4-aminopyridine and Benign Psychomotor Epilepsy, Childhood
Article | Year |
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Sevoflurane reduces synaptic glutamate release in human synaptosomes.
Topics: 4-Aminopyridine; Adult; Anesthetics, Inhalation; Calcium; Cytosol; Epilepsy, Temporal Lobe; Glutamic | 2002 |
22 other studies available for 4-aminopyridine and Benign Psychomotor Epilepsy, Childhood
Article | Year |
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Involvement of GABAergic Interneuron Subtypes in 4-Aminopyridine-Induced Seizure-Like Events in Mouse Entorhinal Cortex
Topics: 4-Aminopyridine; Action Potentials; Animals; Entorhinal Cortex; Epilepsy, Temporal Lobe; Interneuron | 2023 |
Cell-specific NFIA upregulation promotes epileptogenesis by TRPV4-mediated astrocyte reactivity.
Topics: 4-Aminopyridine; Animals; Astrocytes; Brain; Central Nervous System; Epilepsy; Epilepsy, Temporal Lo | 2023 |
Altered A-type potassium channel function in the nucleus tractus solitarii in acquired temporal lobe epilepsy.
Topics: 4-Aminopyridine; Action Potentials; Animals; Brugada Syndrome; Disease Models, Animal; Epilepsy, Tem | 2019 |
Temporal lobe epileptiform activity following systemic administration of 4-aminopyridine in rats.
Topics: 4-Aminopyridine; Animals; Behavior, Animal; CA3 Region, Hippocampal; Electrodes, Implanted; Electroe | 2013 |
A novel electrical stimulation paradigm for the suppression of epileptiform activity in an in vivo model of mesial temporal lobe status epilepticus.
Topics: 4-Aminopyridine; Animals; Biophysics; Disease Models, Animal; Electric Stimulation; Epilepsy, Tempor | 2012 |
Hilar somatostatin interneurons contribute to synchronized GABA activity in an in vitro epilepsy model.
Topics: 4-Aminopyridine; Action Potentials; Animals; Calcium; Epilepsy, Temporal Lobe; gamma-Aminobutyric Ac | 2014 |
Rapid brief feedback intracerebral stimulation based on real-time desynchronization detection preceding seizures stops the generation of convulsive paroxysms.
Topics: 4-Aminopyridine; Animals; CA1 Region, Hippocampal; Disease Models, Animal; Electric Stimulation; Ele | 2015 |
Computational modeling of epileptiform activities in medial temporal lobe epilepsy combined with in vitro experiments.
Topics: 4-Aminopyridine; Entorhinal Cortex; Epilepsy; Epilepsy, Temporal Lobe; Hippocampus; Humans; In Vitro | 2016 |
In vitro ictogenesis and parahippocampal networks in a rodent model of temporal lobe epilepsy.
Topics: 4-Aminopyridine; Action Potentials; Amygdala; Animals; Disease Models, Animal; Electrophysiology; Ep | 2010 |
The immunosuppressant cyclosporin A inhibits recurrent seizures in an experimental model of temporal lobe epilepsy.
Topics: 4-Aminopyridine; Animals; Cyclosporine; Electroencephalography; Epilepsy, Temporal Lobe; Hippocampus | 2012 |
Fiber tract stimulation can reduce epileptiform activity in an in-vitro bilateral hippocampal slice preparation.
Topics: 4-Aminopyridine; Animals; CA1 Region, Hippocampal; CA3 Region, Hippocampal; Electric Stimulation The | 2013 |
Electrophysiologic changes in the lateral and basal amygdaloid nuclei in temporal lobe epilepsy: an in vitro study in epileptic rats.
Topics: 4-Aminopyridine; Amygdala; Animals; Disease Models, Animal; Electric Stimulation; Electroencephalogr | 2004 |
GABAA receptor-dependent synchronization leads to ictogenesis in the human dysplastic cortex.
Topics: 4-Aminopyridine; Adolescent; Adult; Analysis of Variance; Baclofen; Child; Electrophysiology; Epilep | 2004 |
Acquired dendritic channelopathy in temporal lobe epilepsy.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 4-Aminopyridine; Action Potentials; Animals; Butadien | 2004 |
Effects of gap junction blockers on human neocortical synchronization.
Topics: 4-Aminopyridine; Adolescent; Adult; Aged; Brain Diseases; Carbenoxolone; Child; Cortical Synchroniza | 2006 |
Epileptiform synchronization in the rat insular and perirhinal cortices in vitro.
Topics: 4-Aminopyridine; Action Potentials; Animals; Cerebral Cortex; Cortical Synchronization; Epilepsy, Te | 2007 |
CA3-driven hippocampal-entorhinal loop controls rather than sustains in vitro limbic seizures.
Topics: 4-Aminopyridine; Action Potentials; Animals; Convulsants; Dentate Gyrus; Electric Stimulation; Entor | 1997 |
Measured increase in intracellular Ca(2+) during stimulated release of endogenous glutamate from human cerebrocortical synaptosomes.
Topics: 4-Aminopyridine; Animals; Calcium; Cerebral Cortex; Cytosol; Epilepsy, Temporal Lobe; Glutamic Acid; | 1999 |
Epileptiform discharges in the human dysplastic neocortex: in vitro physiology and pharmacology.
Topics: 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Adolescent; Adult; Anticonvulsants; Cerebral | 1999 |
Intrinsic optical signals and electrographic seizures in the rat limbic system.
Topics: 4-Aminopyridine; Action Potentials; Animals; Anticonvulsants; Axotomy; Electric Stimulation; Electro | 2001 |
Effects of antiepileptic drugs on afterdischarge generation in rat hippocampal slices.
Topics: 4-Aminopyridine; Action Potentials; Animals; Anticonvulsants; Bicuculline; Carbamazepine; Dose-Respo | 2002 |
Limbic network interactions leading to hyperexcitability in a model of temporal lobe epilepsy.
Topics: 4-Aminopyridine; Animals; Disease Models, Animal; Entorhinal Cortex; Epilepsy, Temporal Lobe; Hippoc | 2002 |