4-aminopyridine has been researched along with Autism-Dementia-Ataxia-Loss of Purposeful Hand Use Syndrome in 2 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "Rett syndrome is a neurodevelopmental disorder caused by mutations in the X-chromosomal MECP2 gene encoding for the transcriptional regulator methyl CpG binding protein 2 (MeCP2)." | 1.35 | Enhanced hypoxia susceptibility in hippocampal slices from a mouse model of rett syndrome. ( Fischer, M; Gerich, FJ; Hägele, S; Hildebrandt, B; Katschinski, D; Müller, M; Reuter, J, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fischer, M | 1 |
| Reuter, J | 1 |
| Gerich, FJ | 1 |
| Hildebrandt, B | 1 |
| Hägele, S | 1 |
| Katschinski, D | 1 |
| Müller, M | 1 |
| McLeod, F | 1 |
| Ganley, R | 1 |
| Williams, L | 1 |
| Selfridge, J | 1 |
| Bird, A | 1 |
| Cobb, SR | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Rett Syndrome, MECP2 Duplication, and Rett-Related Disorders Consortium, Rare Disease Clinical Research Network: Neurophysiologic Correlates[NCT03077308] | 185 participants (Actual) | Observational | 2017-01-02 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 other studies available for 4-aminopyridine and Autism-Dementia-Ataxia-Loss of Purposeful Hand Use Syndrome
| Article | Year |
|---|---|
Enhanced hypoxia susceptibility in hippocampal slices from a mouse model of rett syndrome.
Topics: 4-Aminopyridine; Adenosine Triphosphate; Animals; Bicuculline; Disease Models, Animal; Disease Susce | 2009 |
Reduced seizure threshold and altered network oscillatory properties in a mouse model of Rett syndrome.
Topics: 4-Aminopyridine; Animals; Bicuculline; Brain Waves; Disease Models, Animal; Excitatory Amino Acid Ag | 2013 |