4-aminopyridine has been researched along with Arrhythmias, Cardiac in 17 studies
Arrhythmias, Cardiac: Any disturbances of the normal rhythmic beating of the heart or MYOCARDIAL CONTRACTION. Cardiac arrhythmias can be classified by the abnormalities in HEART RATE, disorders of electrical impulse generation, or impulse conduction.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The aim of the present experiment was to investigate the possible antiarrhythmic effects of dalfampridine in ouabain-induced arrhythmia in rats." | 7.91 | The potassium channel blocker, dalfampridine diminishes ouabain-induced arrhythmia in isolated rat atria. ( Bakhtiarian, A; Ghebleh Zadeh, N; Mousavi, Z; Nikoui, V; Shiravi, A; Vaezi, G, 2019) |
| " In vivo, cesium-induced EAD, ventricular arrhythmia, and atrioventricular block were suppressed by OPC-88117." | 7.67 | OPC-88117 suppresses early and delayed afterdepolarizations and arrhythmias induced by cesium, 4-aminopyridine and digitalis in canine Purkinje fibers and in the canine heart in situ. ( Gilmour, RF; Graham, B; Stanton, MS; Zipes, DP, 1989) |
| "Flecainide was found to induce extrasystolic activity more readily than other sodium blockers." | 5.29 | Flecainide-induced arrhythmia in canine ventricular epicardium. Phase 2 reentry? ( Antzelevitch, C; Krishnan, SC, 1993) |
| "The aim of the present experiment was to investigate the possible antiarrhythmic effects of dalfampridine in ouabain-induced arrhythmia in rats." | 3.91 | The potassium channel blocker, dalfampridine diminishes ouabain-induced arrhythmia in isolated rat atria. ( Bakhtiarian, A; Ghebleh Zadeh, N; Mousavi, Z; Nikoui, V; Shiravi, A; Vaezi, G, 2019) |
| "The administration of CaCl2 or 4-aminopyridine did not reverse tricyclic antidepressant-induced hypotension in rats." | 3.69 | Effect of calcium chloride and 4-aminopyridine therapy on desipramine toxicity in rats. ( Keyler, DE; Pentel, PR; Wananukul, W, 1996) |
| " In vivo, cesium-induced EAD, ventricular arrhythmia, and atrioventricular block were suppressed by OPC-88117." | 3.67 | OPC-88117 suppresses early and delayed afterdepolarizations and arrhythmias induced by cesium, 4-aminopyridine and digitalis in canine Purkinje fibers and in the canine heart in situ. ( Gilmour, RF; Graham, B; Stanton, MS; Zipes, DP, 1989) |
| "Flecainide was found to induce extrasystolic activity more readily than other sodium blockers." | 1.29 | Flecainide-induced arrhythmia in canine ventricular epicardium. Phase 2 reentry? ( Antzelevitch, C; Krishnan, SC, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (5.88) | 18.7374 |
| 1990's | 5 (29.41) | 18.2507 |
| 2000's | 8 (47.06) | 29.6817 |
| 2010's | 2 (11.76) | 24.3611 |
| 2020's | 1 (5.88) | 2.80 |
| Authors | Studies |
|---|---|
| Holmuhamedov, EL | 1 |
| Chakraborty, P | 1 |
| Oberlin, A | 1 |
| Liu, X | 2 |
| Yousufuddin, M | 1 |
| Shen, WK | 1 |
| Terzic, A | 1 |
| Jahangir, A | 1 |
| Ghebleh Zadeh, N | 1 |
| Vaezi, G | 1 |
| Bakhtiarian, A | 1 |
| Mousavi, Z | 1 |
| Shiravi, A | 1 |
| Nikoui, V | 1 |
| Decker, KF | 1 |
| Heijman, J | 1 |
| Silva, JR | 1 |
| Hund, TJ | 1 |
| Rudy, Y | 1 |
| Zhao, Z | 1 |
| Xie, Y | 1 |
| Wen, H | 1 |
| Xiao, D | 1 |
| Allen, C | 1 |
| Fefelova, N | 1 |
| Dun, W | 1 |
| Boyden, PA | 2 |
| Qu, Z | 1 |
| Xie, LH | 1 |
| Nerbonne, JM | 1 |
| Michels, G | 1 |
| Er, F | 1 |
| Khan, I | 1 |
| Südkamp, M | 1 |
| Herzig, S | 1 |
| Hoppe, UC | 1 |
| Bao, M | 1 |
| Zhang, J | 1 |
| Huang, C | 1 |
| Jiang, H | 1 |
| Liu, J | 1 |
| Zhao, D | 1 |
| Zaniboni, M | 1 |
| Cacciani, F | 1 |
| Salvarani, N | 1 |
| Wang, P | 1 |
| Yang, X | 1 |
| Bao, R | 1 |
| Liu, T | 1 |
| Krishnan, SC | 1 |
| Antzelevitch, C | 1 |
| Wananukul, W | 1 |
| Keyler, DE | 1 |
| Pentel, PR | 1 |
| Pinto, JM | 1 |
| Zhou, J | 1 |
| Jeron, A | 1 |
| London, B | 1 |
| Han, X | 1 |
| Koren, G | 1 |
| Tachibana, H | 1 |
| Yamaki, M | 1 |
| Kubota, I | 1 |
| Watanabe, T | 1 |
| Yamauchi, S | 1 |
| Tomoike, H | 1 |
| Huelsing, DJ | 1 |
| Pollard, AE | 1 |
| Spitzer, KW | 1 |
| Tahara, S | 1 |
| Fukuda, K | 1 |
| Kodama, H | 1 |
| Kato, T | 1 |
| Miyoshi, S | 1 |
| Ogawa, S | 1 |
| Graham, B | 1 |
| Gilmour, RF | 1 |
| Stanton, MS | 1 |
| Zipes, DP | 1 |
1 review available for 4-aminopyridine and Arrhythmias, Cardiac
| Article | Year |
|---|---|
Studying cardiac arrhythmias in the mouse--a reasonable model for probing mechanisms?
Topics: 4-Aminopyridine; Action Potentials; Animals; Arrhythmias, Cardiac; Disease Models, Animal; ERG1 Pota | 2004 |
16 other studies available for 4-aminopyridine and Arrhythmias, Cardiac
| Article | Year |
|---|---|
Aging-associated susceptibility to stress-induced ventricular arrhythmogenesis is attenuated by tetrodotoxin.
Topics: 4-Aminopyridine; Action Potentials; Aging; Animals; Arrhythmias, Cardiac; Isoproterenol; Male; Myocy | 2022 |
The potassium channel blocker, dalfampridine diminishes ouabain-induced arrhythmia in isolated rat atria.
Topics: 4-Aminopyridine; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Dose-Response Relationship, | 2019 |
Properties and ionic mechanisms of action potential adaptation, restitution, and accommodation in canine epicardium.
Topics: 4-Aminopyridine; Action Potentials; Animals; Arrhythmias, Cardiac; Calcium; Calcium Channels, L-Type | 2009 |
Role of the transient outward potassium current in the genesis of early afterdepolarizations in cardiac cells.
Topics: 4-Aminopyridine; Action Potentials; Animals; Arrhythmias, Cardiac; Calcium; Calcium Channels, L-Type | 2012 |
Single-channel properties support a potential contribution of hyperpolarization-activated cyclic nucleotide-gated channels and If to cardiac arrhythmias.
Topics: 4-Aminopyridine; Aged; Animals; Arrhythmias, Cardiac; Atrial Appendage; Cells, Cultured; CHO Cells; | 2005 |
Abnormal intracellular calcium handling underlying T-wave alternans and its hysteresis.
Topics: 4-Aminopyridine; Animals; Arrhythmias, Cardiac; Calcium; Calcium Signaling; Electrocardiography; End | 2007 |
Temporal variability of repolarization in rat ventricular myocytes paced with time-varying frequencies.
Topics: 4-Aminopyridine; Action Potentials; Animals; Arrhythmias, Cardiac; Calcium Channel Blockers; Calcium | 2007 |
The characteristics of action potential and nonselective cation current of cardiomyocytes in rabbit superior vena cava.
Topics: 4-Aminopyridine; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Action Potentials; Animals; Arrhy | 2008 |
Flecainide-induced arrhythmia in canine ventricular epicardium. Phase 2 reentry?
Topics: 4-Aminopyridine; Action Potentials; Animals; Arrhythmias, Cardiac; Dogs; Endocardium; Flecainide; He | 1993 |
Effect of calcium chloride and 4-aminopyridine therapy on desipramine toxicity in rats.
Topics: 4-Aminopyridine; Animals; Antidepressive Agents, Tricyclic; Arrhythmias, Cardiac; Blood Pressure; Br | 1996 |
Reduced inward rectifying and increased E-4031-sensitive K+ current density in arrhythmogenic subendocardial purkinje myocytes from the infarcted heart.
Topics: 4-Aminopyridine; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Calcium Channel Blockers; Ce | 1998 |
Characterization of a slowly inactivating outward current in adult mouse ventricular myocytes.
Topics: 4-Aminopyridine; Action Potentials; Animals; Arrhythmias, Cardiac; Cesium; Heart Ventricles; Ion Cha | 1998 |
Intracoronary flecainide induces ST alternans and reentrant arrhythmia on intact canine heart: A role of 4-aminopyridine-sensitive current.
Topics: 4-Aminopyridine; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Coronary Vessels; Disopyrami | 1999 |
Transient outward current modulates discontinuous conduction in rabbit ventricular cell pairs.
Topics: 4-Aminopyridine; Action Potentials; Animals; Arrhythmias, Cardiac; Cell Communication; Cell Separati | 2001 |
Potassium channel blocker activates extracellular signal-regulated kinases through Pyk2 and epidermal growth factor receptor in rat cardiomyocytes.
Topics: 4-Aminopyridine; Action Potentials; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Calcium C | 2001 |
OPC-88117 suppresses early and delayed afterdepolarizations and arrhythmias induced by cesium, 4-aminopyridine and digitalis in canine Purkinje fibers and in the canine heart in situ.
Topics: 4-Aminopyridine; Action Potentials; Animals; Arrhythmias, Cardiac; Cardiovascular Agents; Cesium; Di | 1989 |