4-aminopyridine has been researched along with Arrhythmia in 17 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "The aim of the present experiment was to investigate the possible antiarrhythmic effects of dalfampridine in ouabain-induced arrhythmia in rats." | 7.91 | The potassium channel blocker, dalfampridine diminishes ouabain-induced arrhythmia in isolated rat atria. ( Bakhtiarian, A; Ghebleh Zadeh, N; Mousavi, Z; Nikoui, V; Shiravi, A; Vaezi, G, 2019) |
| " In vivo, cesium-induced EAD, ventricular arrhythmia, and atrioventricular block were suppressed by OPC-88117." | 7.67 | OPC-88117 suppresses early and delayed afterdepolarizations and arrhythmias induced by cesium, 4-aminopyridine and digitalis in canine Purkinje fibers and in the canine heart in situ. ( Gilmour, RF; Graham, B; Stanton, MS; Zipes, DP, 1989) |
| "Flecainide was found to induce extrasystolic activity more readily than other sodium blockers." | 5.29 | Flecainide-induced arrhythmia in canine ventricular epicardium. Phase 2 reentry? ( Antzelevitch, C; Krishnan, SC, 1993) |
| "The aim of the present experiment was to investigate the possible antiarrhythmic effects of dalfampridine in ouabain-induced arrhythmia in rats." | 3.91 | The potassium channel blocker, dalfampridine diminishes ouabain-induced arrhythmia in isolated rat atria. ( Bakhtiarian, A; Ghebleh Zadeh, N; Mousavi, Z; Nikoui, V; Shiravi, A; Vaezi, G, 2019) |
| "The administration of CaCl2 or 4-aminopyridine did not reverse tricyclic antidepressant-induced hypotension in rats." | 3.69 | Effect of calcium chloride and 4-aminopyridine therapy on desipramine toxicity in rats. ( Keyler, DE; Pentel, PR; Wananukul, W, 1996) |
| " In vivo, cesium-induced EAD, ventricular arrhythmia, and atrioventricular block were suppressed by OPC-88117." | 3.67 | OPC-88117 suppresses early and delayed afterdepolarizations and arrhythmias induced by cesium, 4-aminopyridine and digitalis in canine Purkinje fibers and in the canine heart in situ. ( Gilmour, RF; Graham, B; Stanton, MS; Zipes, DP, 1989) |
| "Flecainide was found to induce extrasystolic activity more readily than other sodium blockers." | 1.29 | Flecainide-induced arrhythmia in canine ventricular epicardium. Phase 2 reentry? ( Antzelevitch, C; Krishnan, SC, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (5.88) | 18.7374 |
| 1990's | 5 (29.41) | 18.2507 |
| 2000's | 8 (47.06) | 29.6817 |
| 2010's | 2 (11.76) | 24.3611 |
| 2020's | 1 (5.88) | 2.80 |
| Authors | Studies |
|---|---|
| Holmuhamedov, EL | 1 |
| Chakraborty, P | 1 |
| Oberlin, A | 1 |
| Liu, X | 2 |
| Yousufuddin, M | 1 |
| Shen, WK | 1 |
| Terzic, A | 1 |
| Jahangir, A | 1 |
| Ghebleh Zadeh, N | 1 |
| Vaezi, G | 1 |
| Bakhtiarian, A | 1 |
| Mousavi, Z | 1 |
| Shiravi, A | 1 |
| Nikoui, V | 1 |
| Decker, KF | 1 |
| Heijman, J | 1 |
| Silva, JR | 1 |
| Hund, TJ | 1 |
| Rudy, Y | 1 |
| Zhao, Z | 1 |
| Xie, Y | 1 |
| Wen, H | 1 |
| Xiao, D | 1 |
| Allen, C | 1 |
| Fefelova, N | 1 |
| Dun, W | 1 |
| Boyden, PA | 2 |
| Qu, Z | 1 |
| Xie, LH | 1 |
| Nerbonne, JM | 1 |
| Michels, G | 1 |
| Er, F | 1 |
| Khan, I | 1 |
| Südkamp, M | 1 |
| Herzig, S | 1 |
| Hoppe, UC | 1 |
| Bao, M | 1 |
| Zhang, J | 1 |
| Huang, C | 1 |
| Jiang, H | 1 |
| Liu, J | 1 |
| Zhao, D | 1 |
| Zaniboni, M | 1 |
| Cacciani, F | 1 |
| Salvarani, N | 1 |
| Wang, P | 1 |
| Yang, X | 1 |
| Bao, R | 1 |
| Liu, T | 1 |
| Krishnan, SC | 1 |
| Antzelevitch, C | 1 |
| Wananukul, W | 1 |
| Keyler, DE | 1 |
| Pentel, PR | 1 |
| Pinto, JM | 1 |
| Zhou, J | 1 |
| Jeron, A | 1 |
| London, B | 1 |
| Han, X | 1 |
| Koren, G | 1 |
| Tachibana, H | 1 |
| Yamaki, M | 1 |
| Kubota, I | 1 |
| Watanabe, T | 1 |
| Yamauchi, S | 1 |
| Tomoike, H | 1 |
| Huelsing, DJ | 1 |
| Pollard, AE | 1 |
| Spitzer, KW | 1 |
| Tahara, S | 1 |
| Fukuda, K | 1 |
| Kodama, H | 1 |
| Kato, T | 1 |
| Miyoshi, S | 1 |
| Ogawa, S | 1 |
| Graham, B | 1 |
| Gilmour, RF | 1 |
| Stanton, MS | 1 |
| Zipes, DP | 1 |
1 review available for 4-aminopyridine and Arrhythmia
| Article | Year |
|---|---|
Studying cardiac arrhythmias in the mouse--a reasonable model for probing mechanisms?
Topics: 4-Aminopyridine; Action Potentials; Animals; Arrhythmias, Cardiac; Disease Models, Animal; ERG1 Pota | 2004 |
16 other studies available for 4-aminopyridine and Arrhythmia
| Article | Year |
|---|---|
Aging-associated susceptibility to stress-induced ventricular arrhythmogenesis is attenuated by tetrodotoxin.
Topics: 4-Aminopyridine; Action Potentials; Aging; Animals; Arrhythmias, Cardiac; Isoproterenol; Male; Myocy | 2022 |
The potassium channel blocker, dalfampridine diminishes ouabain-induced arrhythmia in isolated rat atria.
Topics: 4-Aminopyridine; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Dose-Response Relationship, | 2019 |
Properties and ionic mechanisms of action potential adaptation, restitution, and accommodation in canine epicardium.
Topics: 4-Aminopyridine; Action Potentials; Animals; Arrhythmias, Cardiac; Calcium; Calcium Channels, L-Type | 2009 |
Role of the transient outward potassium current in the genesis of early afterdepolarizations in cardiac cells.
Topics: 4-Aminopyridine; Action Potentials; Animals; Arrhythmias, Cardiac; Calcium; Calcium Channels, L-Type | 2012 |
Single-channel properties support a potential contribution of hyperpolarization-activated cyclic nucleotide-gated channels and If to cardiac arrhythmias.
Topics: 4-Aminopyridine; Aged; Animals; Arrhythmias, Cardiac; Atrial Appendage; Cells, Cultured; CHO Cells; | 2005 |
Abnormal intracellular calcium handling underlying T-wave alternans and its hysteresis.
Topics: 4-Aminopyridine; Animals; Arrhythmias, Cardiac; Calcium; Calcium Signaling; Electrocardiography; End | 2007 |
Temporal variability of repolarization in rat ventricular myocytes paced with time-varying frequencies.
Topics: 4-Aminopyridine; Action Potentials; Animals; Arrhythmias, Cardiac; Calcium Channel Blockers; Calcium | 2007 |
The characteristics of action potential and nonselective cation current of cardiomyocytes in rabbit superior vena cava.
Topics: 4-Aminopyridine; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Action Potentials; Animals; Arrhy | 2008 |
Flecainide-induced arrhythmia in canine ventricular epicardium. Phase 2 reentry?
Topics: 4-Aminopyridine; Action Potentials; Animals; Arrhythmias, Cardiac; Dogs; Endocardium; Flecainide; He | 1993 |
Effect of calcium chloride and 4-aminopyridine therapy on desipramine toxicity in rats.
Topics: 4-Aminopyridine; Animals; Antidepressive Agents, Tricyclic; Arrhythmias, Cardiac; Blood Pressure; Br | 1996 |
Reduced inward rectifying and increased E-4031-sensitive K+ current density in arrhythmogenic subendocardial purkinje myocytes from the infarcted heart.
Topics: 4-Aminopyridine; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Calcium Channel Blockers; Ce | 1998 |
Characterization of a slowly inactivating outward current in adult mouse ventricular myocytes.
Topics: 4-Aminopyridine; Action Potentials; Animals; Arrhythmias, Cardiac; Cesium; Heart Ventricles; Ion Cha | 1998 |
Intracoronary flecainide induces ST alternans and reentrant arrhythmia on intact canine heart: A role of 4-aminopyridine-sensitive current.
Topics: 4-Aminopyridine; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Coronary Vessels; Disopyrami | 1999 |
Transient outward current modulates discontinuous conduction in rabbit ventricular cell pairs.
Topics: 4-Aminopyridine; Action Potentials; Animals; Arrhythmias, Cardiac; Cell Communication; Cell Separati | 2001 |
Potassium channel blocker activates extracellular signal-regulated kinases through Pyk2 and epidermal growth factor receptor in rat cardiomyocytes.
Topics: 4-Aminopyridine; Action Potentials; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Calcium C | 2001 |
OPC-88117 suppresses early and delayed afterdepolarizations and arrhythmias induced by cesium, 4-aminopyridine and digitalis in canine Purkinje fibers and in the canine heart in situ.
Topics: 4-Aminopyridine; Action Potentials; Animals; Arrhythmias, Cardiac; Cardiovascular Agents; Cesium; Di | 1989 |