4-aminopyridine has been researched along with Anesthesia in 22 studies
Anesthesia: A state characterized by loss of feeling or sensation. This depression of nerve function is usually the result of pharmacologic action and is induced to allow performance of surgery or other painful procedures.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Antagonism of ketamine-xylazine (85 mg of ketamine/kg of body weight and 15 mg of xylazine/kg, IM) anesthesia in rats by yohimbine (YOH; 1, 5, 10, and 20 mg/kg, IP), tolazoline (TOL; 10, 20, or 50 mg/kg, IP), 4-aminopyridine (4-AP; 1 or 5 mg/kg, IP), or a combination of yohimbine and 4-aminopyridine (YOH:4-AP, 1 mg/kg:1 mg/kg or 5 mg/kg:1 mg/kg, IP) was studied." | 7.68 | Antagonism of ketamine-xylazine anesthesia in rats by administration of yohimbine, tolazoline, or 4-aminopyridine. ( Komulainen, A; Olson, ME, 1991) |
| " Using a dosage of 3-5 mg/kg there is a marked negative effect on the cardio-vascular system." | 5.28 | [The antagonism of ketamine/xylazine anesthesia ("Hellabrunn mixture") in wild zoo ruminants]. ( Erhardt, W; Hafner, S; Halm, S; von Hegel, G; Wiesner, H, 1989) |
| "Suramin was without effect on heart rate or blood pressure in the doses used." | 1.29 | Reversal by suramin of neuromuscular block produced by pancuronium in the anaesthetized rat. ( Agoston, S; Henning, RH; Houwertjes, M; Nelemans, A, 1993) |
| " Using a dosage of 3-5 mg/kg there is a marked negative effect on the cardio-vascular system." | 1.28 | [The antagonism of ketamine/xylazine anesthesia ("Hellabrunn mixture") in wild zoo ruminants]. ( Erhardt, W; Hafner, S; Halm, S; von Hegel, G; Wiesner, H, 1989) |
| " Serum data best fit a three-compartment pharmacokinetic model." | 1.27 | Pharmacokinetics and pharmacodynamics of 4-aminopyridine in anesthetized dogs. ( Castagnoli, N; Fisher, DM; Miller, RD; Rupp, SM; Shinohara, Y, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (45.45) | 18.7374 |
| 1990's | 6 (27.27) | 18.2507 |
| 2000's | 4 (18.18) | 29.6817 |
| 2010's | 2 (9.09) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ueoka, N | 2 |
| Hikasa, Y | 2 |
| Canning, BJ | 1 |
| Mori, N | 1 |
| Ma, HC | 1 |
| Wang, YF | 1 |
| Feng, CS | 1 |
| Zhao, H | 1 |
| Dohi, S | 1 |
| Rensing, N | 1 |
| Ouyang, Y | 1 |
| Yang, XF | 1 |
| Yamada, KA | 1 |
| Rothman, SM | 1 |
| Wong, M | 1 |
| Wirtavuori, K | 1 |
| Salmenperä, M | 1 |
| Tammisto, T | 1 |
| Langrehr, D | 2 |
| Agoston, S | 3 |
| Sia, R | 1 |
| Durant, NN | 1 |
| Nguyen, N | 1 |
| Lee, C | 1 |
| Katz, RL | 1 |
| Schmutzler, S | 1 |
| Uges, D | 1 |
| Rupp, SM | 1 |
| Shinohara, Y | 1 |
| Fisher, DM | 1 |
| Miller, RD | 1 |
| Castagnoli, N | 1 |
| Casamenti, F | 1 |
| Corradetti, R | 1 |
| Löffelholz, K | 2 |
| Mantovani, P | 1 |
| Pepeu, G | 1 |
| Kontani, H | 1 |
| Ginkawa, M | 1 |
| Sakai, T | 1 |
| Henning, RH | 1 |
| Nelemans, A | 1 |
| Houwertjes, M | 1 |
| Matsumoto, S | 2 |
| Takahashi, T | 1 |
| Tanimoto, T | 2 |
| Saiki, C | 2 |
| Takeda, M | 2 |
| Ikeda, M | 1 |
| Nishikawa, T | 1 |
| Yoshida, S | 1 |
| Ito, M | 1 |
| Misgeld, U | 1 |
| Bijak, M | 1 |
| Brunner, H | 1 |
| Dembowsky, K | 1 |
| Verstegen, J | 1 |
| Fargetton, X | 1 |
| Zanker, S | 1 |
| Donnay, I | 1 |
| Ectors, F | 1 |
| Komulainen, A | 1 |
| Olson, ME | 1 |
| Hafner, S | 1 |
| Wiesner, H | 1 |
| von Hegel, G | 1 |
| Halm, S | 1 |
| Erhardt, W | 1 |
| Uchiyama, T | 1 |
| Lemeignan, M | 1 |
| Lechat, P | 1 |
| Böhmer, G | 1 |
| Schmid, K | 1 |
| Raach, M | 1 |
| Gouzoulis, E | 1 |
| Hatch, RC | 1 |
| Jernigan, AD | 1 |
| Wilson, RC | 1 |
| Lipham, IB | 1 |
| Booth, NH | 1 |
| Clark, JD | 1 |
| Brown, J | 1 |
1 review available for 4-aminopyridine and Anesthesia
| Article | Year |
|---|---|
Ataranalgesia. A review.
Topics: 4-Aminopyridine; Aminopyridines; Anesthesia; Animals; Anti-Anxiety Agents; Benzodiazepines; Drug Com | 1984 |
21 other studies available for 4-aminopyridine and Anesthesia
| Article | Year |
|---|---|
Effects in cats of atipamezole, flumazenil and 4-aminopyridine on stress-related neurohormonal and metabolic responses induced by medetomidine, midazolam and ketamine.
Topics: 4-Aminopyridine; Anesthesia; Anesthetics, Combined; Animals; Arousal; Cats; Dose-Response Relationsh | 2015 |
Encoding of the cough reflex in anesthetized guinea pigs.
Topics: 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Anesthesia; Animals; Biphenyl Compounds; Citr | 2011 |
Effects of adenosine agonist R-phenylisopropyl-adenosine on halothane anesthesia and antinociception in rats.
Topics: 4-Aminopyridine; Adenosine; Adenosine A1 Receptor Antagonists; Analgesia; Analgesics; Anesthesia; An | 2005 |
In vivo imaging of dendritic spines during electrographic seizures.
Topics: 4-Aminopyridine; Anesthesia; Animals; Convulsants; Dendritic Spines; Electroencephalography; Epileps | 2005 |
Antagonistic effects of atipamezole, flumazenil and 4-aminopyridine against anaesthesia with medetomidine, midazolam and ketamine combination in cats.
Topics: 4-Aminopyridine; Anesthesia; Anesthetics, Combined; Anesthetics, Dissociative; Anesthetics, Intraven | 2008 |
Antagonism of d-tubocurarine-induced neuromuscular blockade with a mixture of 4-aminopyridine and neostigmine in man.
Topics: 4-Aminopyridine; Adult; Aminopyridines; Anesthesia; Blood Pressure; Electromyography; Female; Heart | 1984 |
A comparison of 3,4-diaminopyridine and 4-aminopyridine in the anaesthetized cat.
Topics: 4-Aminopyridine; Amifampridine; Aminopyridines; Anesthesia; Animals; Blood Pressure; Cats; Female; H | 1982 |
[Rohypnol poisoning as a cause of postanesthetic coma and the success of 4-aminopyridine therapy].
Topics: 4-Aminopyridine; Adult; Aminopyridines; Anesthesia; Coma; Female; Flunitrazepam; Humans; Naloxone; P | 1984 |
Pharmacokinetics and pharmacodynamics of 4-aminopyridine in anesthetized dogs.
Topics: 4-Aminopyridine; Aminopyridines; Anesthesia; Animals; Dogs; Half-Life; Kinetics; Muscle Contraction; | 1983 |
Effects of 4-aminopyridine on acetylcholine output from the cerebral cortex of the rat in vivo.
Topics: 4-Aminopyridine; Acetylcholine; Aminopyridines; Anesthesia; Animals; Blood Pressure; Cerebral Cortex | 1982 |
A simple method for measurement of ureteric peristaltic function in vivo and the effects of drugs acting on ion channels applied from the ureter lumen in anesthetized rats.
Topics: 4-Aminopyridine; Anesthesia; Animals; Benzopyrans; Cromakalim; Glyburide; Ion Channels; Lidocaine; M | 1993 |
Reversal by suramin of neuromuscular block produced by pancuronium in the anaesthetized rat.
Topics: 4-Aminopyridine; Anesthesia; Animals; Electric Stimulation; Isometric Contraction; Male; Neostigmine | 1993 |
Effects of potassium channel blockers on CO2-induced slowly adapting pulmonary stretch receptor inhibition.
Topics: 4-Aminopyridine; Adaptation, Physiological; Administration, Inhalation; Anesthesia; Animals; Carbon | 1999 |
Excitatory mechanism of deflationary slowly adapting pulmonary stretch receptors in the rat lung.
Topics: 4-Aminopyridine; Anesthesia; Animals; Anti-Arrhythmia Agents; Flecainide; Injections, Intravenous; L | 2002 |
K-dependent inhibition in the dentate-CA3 network of guinea pig hippocampal slices.
Topics: 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Anesthesia; Animals; Cytoplasmic Granules; Gu | 1992 |
Antagonistic activities of atipamezole, 4-aminopyridine and yohimbine against medetomidine/ketamine-induced anaesthesia in cats.
Topics: 4-Aminopyridine; Anesthesia; Animals; Cats; Heart Rate; Imidazoles; Injections, Intramuscular; Ketam | 1991 |
Antagonism of ketamine-xylazine anesthesia in rats by administration of yohimbine, tolazoline, or 4-aminopyridine.
Topics: 4-Aminopyridine; Anesthesia; Animals; Body Temperature; Female; Ketamine; Rats; Rats, Inbred Strains | 1991 |
[The antagonism of ketamine/xylazine anesthesia ("Hellabrunn mixture") in wild zoo ruminants].
Topics: 4-Aminopyridine; Aminopyridines; Anesthesia; Animals; Animals, Zoo; Central Nervous System Stimulant | 1989 |
Equipotency of anti-curare activity of 4-aminopyridine and 3,4-diaminopyridine in anesthetized rats.
Topics: 4-Aminopyridine; Amifampridine; Aminopyridines; Anesthesia; Animals; In Vitro Techniques; Male; Musc | 1985 |
Dopaminergic control of respiration as shown by effects of 4-aminopyridine.
Topics: 4-Aminopyridine; Aminopyridines; Anesthesia; Animals; Atropine; Domperidone; Dopamine; Haloperidol; | 1986 |
Prompt arousal from fentanyl-droperidol-pentobarbital anesthesia in dogs: a preliminary study.
Topics: 4-Aminopyridine; Aminopyridines; Anesthesia; Anesthetics; Animals; Arousal; Dogs; Doxapram; Droperid | 1986 |