4-aminopyridine has been researched along with Adult Spinal Muscular Atrophy in 4 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "Hereditary Canine Spinal Muscular Atrophy (HCSMA) is an autosomal dominant disorder of motor neurons that shares features with human motor neuron disease." | 1.30 | Effects of 4-aminopyridine on muscle and motor unit force in canine motor neuron disease. ( Cope, TC; Cork, LC; Pinter, MJ; Waldeck, RF, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 2 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chiriboga, CA | 1 |
| Marra, J | 1 |
| LaMarca, NM | 1 |
| Young, SD | 1 |
| Weimer, LH | 1 |
| Levin, B | 1 |
| McCabe, B | 1 |
| Simon, CM | 1 |
| Blanco-Redondo, B | 1 |
| Buettner, JM | 1 |
| Pagiazitis, JG | 1 |
| Fletcher, EV | 1 |
| Sime Longang, JK | 1 |
| Mentis, GZ | 1 |
| Sleigh, JN | 1 |
| Buckingham, SD | 1 |
| Esmaeili, B | 1 |
| Viswanathan, M | 1 |
| Cuppen, E | 1 |
| Westlund, BM | 1 |
| Sattelle, DB | 1 |
| Pinter, MJ | 1 |
| Waldeck, RF | 1 |
| Cope, TC | 1 |
| Cork, LC | 1 |
1 trial available for 4-aminopyridine and Adult Spinal Muscular Atrophy
| Article | Year |
|---|---|
Lack of effect on ambulation of dalfampridine-ER (4-AP) treatment in adult SMA patients.
Topics: 4-Aminopyridine; Adult; Cross-Over Studies; Double-Blind Method; Fatigue; Female; Humans; Male; Midd | 2020 |
3 other studies available for 4-aminopyridine and Adult Spinal Muscular Atrophy
| Article | Year |
|---|---|
Chronic Pharmacological Increase of Neuronal Activity Improves Sensory-Motor Dysfunction in Spinal Muscular Atrophy Mice.
Topics: 4-Aminopyridine; Animals; Cell Death; Mice; Mice, Knockout; Motor Neurons; Movement Disorders; Muscu | 2021 |
A novel Caenorhabditis elegans allele, smn-1(cb131), mimicking a mild form of spinal muscular atrophy, provides a convenient drug screening platform highlighting new and pre-approved compounds.
Topics: 4-Aminopyridine; Alleles; Amino Acid Sequence; Animals; Caenorhabditis elegans; Disease Models, Anim | 2011 |
Effects of 4-aminopyridine on muscle and motor unit force in canine motor neuron disease.
Topics: 4-Aminopyridine; Animals; Calcium; Disease Models, Animal; Dogs; Electromyography; Female; Homozygot | 1997 |